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Wyszukujesz frazę ""Trypsin inhibitor"" wg kryterium: Temat


Tytuł:
Elemental sulfur concentration can be used as a rapid, reliable, and cost-effective predictor of sulfur amino acid content of soybean seeds.
Autorzy:
Kim W; Division of Plant Science and Technology, University of Missouri, Columbia, MO, 65211, USA.
Kim S; Division of Plant Science and Technology, University of Missouri, Columbia, MO, 65211, USA.
Mawhinney TP; Department of Biochemistry, University of Missouri, Columbia, MO, 65211, USA.
Krishnan HB; Division of Plant Science and Technology, University of Missouri, Columbia, MO, 65211, USA. .; Plant Genetics Research Unit, USDA, Agricultural Research Service, University of Missouri, 108 Curtis Hall, Columbia, MO, 65211, USA. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3093. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Trypsin Inhibitor, Bowman-Birk Soybean*/chemistry
Amino Acids, Sulfur*/metabolism
Glycine max ; Cysteine/metabolism ; Cost-Benefit Analysis ; Methionine/metabolism ; Seeds/metabolism ; Protease Inhibitors/metabolism
Czasopismo naukowe
Tytuł:
SPINK1 Overexpression Correlates with Hepatocellular Carcinoma Treatment Resistance Revealed by Single Cell RNA-Sequencing and Spatial Transcriptomics.
Autorzy:
Yang C; Institute of Systems Biomedicine, Department of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
Guo L; Institute of Systems Biomedicine, Department of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
Du J; Institute of Systems Biomedicine, Department of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
Zhang Q; Institute of Systems Biomedicine, Department of Pathology, School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
Zhang L; Department of General Surgery, Peking University Third Hospital, Beijing 100191, China.
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Źródło:
Biomolecules [Biomolecules] 2024 Feb 22; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Liver Neoplasms*/metabolism
Humans ; Trypsin Inhibitor, Kazal Pancreatic/genetics ; Trypsin Inhibitor, Kazal Pancreatic/metabolism ; Trypsin Inhibitor, Kazal Pancreatic/therapeutic use ; Cytochrome P-450 CYP3A/genetics ; Gene Expression Profiling ; RNA ; Drug Resistance, Neoplasm/genetics ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
The Preventive Effect of Urinary Trypsin Inhibitor on Postoperative Cognitive Dysfunction, on the Aspect of Behavior, Evaluated by Y-Maze Test, via Modulation of Microglial Activity.
Autorzy:
Cho, Eun-Hwa (AUTHOR)
In, Chi-Bum (AUTHOR)
Lee, Gyu-Won (AUTHOR)
Hong, Seung-Wan (AUTHOR)
Seo, Eun-Hye (AUTHOR)
Lee, Won Hyung (AUTHOR)
Kim, Seong-Hyop (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 5, p2708. 12p.
Czasopismo naukowe
Tytuł:
Tumor microenvironment deconvolution identifies cell-type-independent aberrant DNA methylation and gene expression in prostate cancer.
Autorzy:
Reynolds SR; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA. .
Zhang Z; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Salas LA; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Christensen BC; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
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Źródło:
Clinical epigenetics [Clin Epigenetics] 2024 Jan 03; Vol. 16 (1), pp. 5. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
DNA Methylation*
Prostatic Neoplasms*/pathology
Male ; Humans ; Epigenesis, Genetic ; Tumor Microenvironment/genetics ; CpG Islands ; Gene Expression ; Trypsin Inhibitor, Kazal Pancreatic/genetics ; Trypsin Inhibitor, Kazal Pancreatic/metabolism
Czasopismo naukowe
Tytuł:
Pancreatic Secretory Trypsin Inhibitor (SPINK1) Gene Mutation in Patients with Acute Alcohol Pancreatitis (AAP) Compared to Healthy Controls and Heavy Alcohol Users without Pancreatitis.
Autorzy:
Nikkola A; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, 33520 Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland.
Mäkelä KA; Research Unit of Biomedicine, Oulu University, 90220 Oulu, Finland.
Herzig KH; Research Unit of Biomedicine, Oulu University, 90220 Oulu, Finland.; Medical Research Center Oulu, Oulu University, Oulu University Hospital, 90220 Oulu, Finland.; Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, 60-572 Poznan, Poland.
Mutt SJ; Research Unit of Biomedicine, Oulu University, 90220 Oulu, Finland.
Prasannan A; Research Unit of Biomedicine, Oulu University, 90220 Oulu, Finland.
Seppänen H; Department of Surgery, Helsinki University Hospital, 00260 Helsinki, Finland.
Lehtimäki T; Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland.; Fimlab Laboratories, Department of Clinical Chemistry, 33520 Tampere, Finland.; Finnish Cardiovascular Research Center, 33520 Tampere, Finland.
Kähönen M; Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland.; Finnish Cardiovascular Research Center, 33520 Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, 33520 Tampere, Finland.
Raitakari O; Centre for Population Health Research, University of Turku and Turku University Hospital, 20521 Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20014 Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, 20521 Turku, Finland.
Seppälä I; Fimlab Laboratories, Department of Clinical Chemistry, 33520 Tampere, Finland.
Pakkanen P; Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland.; Department of Otorhinolaryngology-Head and Neck Surgery, Helsinki University Hospital, 00260 Helsinki, Finland.
Nordback I; Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland.
Sand J; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, 33520 Tampere, Finland.
Laukkarinen J; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, 33520 Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 11; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatitis*/genetics
Trypsin Inhibitor, Kazal Pancreatic*/genetics
Alcohol Drinking*/adverse effects
Humans ; Genetic Predisposition to Disease ; Mutation ; Risk Factors ; Trypsin/genetics
Czasopismo naukowe
Tytuł:
血必净联合乌司他丁对坏死性小肠结肠炎新生儿炎性反应 和心肌保护作用研究.
Autorzy:
莫力
贾杰
黄景思
肖尚杰
黎昆伟
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Alternatywny tytuł:
Study on the Effect of Xuebijing Combined with Ulinastatin on Inflammatory Response and Myocardial Protection of Neonatus with Necrotizing Enterocolitis.
Źródło:
Progress in Modern Biomedicine. Oct2023, Vol. 23 Issue 19, p3763-3703. 6p.
Czasopismo naukowe
Tytuł:
Raised SPINK1 levels play a role in angiogenesis and the transendothelial migration of ALL cells.
Autorzy:
Luo D; Medical Laboratory, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan City, Guangdong Province, China.; Department of Medical and Molecular Genetics, Dongguan Institute of Pediatrics, Dongguan, Guangdong, China.
Liu D; Department of Hematology, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan City, Guangdong Province, China.
Rao C; Medical Laboratory, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan City, Guangdong Province, China.; Department of Medical and Molecular Genetics, Dongguan Institute of Pediatrics, Dongguan, Guangdong, China.
Shi S; Department of Neurology, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan, Guangdong, China.
Zeng X; Medical Laboratory, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan City, Guangdong Province, China.; Department of Medical and Molecular Genetics, Dongguan Institute of Pediatrics, Dongguan, Guangdong, China.
Liu S; Department of Hematology-Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China.
Jiang H; Department of Hematology-Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China.
Liu L; Department of Hematology, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan City, Guangdong Province, China.
Zhang Z; Department of Hematology, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan City, Guangdong Province, China. .
Lu X; Medical Laboratory, Dongguan Children's Hospital Affiliated to Guangdong Medical University, Dongguan City, Guangdong Province, China. .; Department of Medical and Molecular Genetics, Dongguan Institute of Pediatrics, Dongguan, Guangdong, China. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 22; Vol. 12 (1), pp. 2999. Date of Electronic Publication: 2022 Feb 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Movement/*genetics
Gene Expression/*genetics
Gene Expression/*physiology
Neovascularization, Pathologic/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*pathology
Trypsin Inhibitor, Kazal Pancreatic/*genetics
Trypsin Inhibitor, Kazal Pancreatic/*physiology
Animals ; Coculture Techniques ; Disease Models, Animal ; Endothelial Cells/pathology ; Female ; Human Umbilical Vein Endothelial Cells ; Humans ; Intercellular Adhesion Molecule-1/genetics ; Intercellular Adhesion Molecule-1/metabolism ; Interleukin-8/genetics ; Interleukin-8/metabolism ; MAP Kinase Signaling System/genetics ; MAP Kinase Signaling System/physiology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neovascularization, Pathologic/pathology ; Trypsin Inhibitor, Kazal Pancreatic/metabolism ; Vascular Cell Adhesion Molecule-1/genetics ; Vascular Cell Adhesion Molecule-1/metabolism
Czasopismo naukowe
Tytuł:
Prevalence and Risk Factors of Germline Pathogenic Variants in Pancreatic Ductal Adenocarcinoma.
Autorzy:
Ryu KH; Center for Cancer Prevention and Detection, National Cancer Center, Goyang, Korea.
Park S; Targeted Therapy Branch, Center for Rare Cancers, National Cancer Center, Goyang, Korea.
Chun JW; Center for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang, Korea.
Cho E; GC Genome, Green Cross Laboratories, Yongin, Korea.
Choi J; GC Genome, Green Cross Laboratories, Yongin, Korea.
Lee DE; Biostatics Collaboration Team, Research Institute, National Cancer Center, Goyang, Korea.
Shim H; Department of Laboratory Medicine, Hospital, National Cancer Center, Goyang, Korea.
Kim YH; Cancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang, Korea.; Division of Convergence Technology, Research Institute, National Cancer Center, Goyang, Korea.
Han SS; Center for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang, Korea.
Park SJ; Center for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang, Korea.
Woo SM; Center for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang, Korea.; Cancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang, Korea.
Kong SY; Targeted Therapy Branch, Center for Rare Cancers, National Cancer Center, Goyang, Korea.; Department of Laboratory Medicine, Hospital, National Cancer Center, Goyang, Korea.; Cancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang, Korea.
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Źródło:
Cancer research and treatment [Cancer Res Treat] 2023 Oct; Vol. 55 (4), pp. 1303-1312. Date of Electronic Publication: 2023 Apr 03.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatic Neoplasms*/epidemiology
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/pathology
Carcinoma, Pancreatic Ductal*/epidemiology
Carcinoma, Pancreatic Ductal*/genetics
Humans ; Male ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Prevalence ; Risk Factors ; Trypsin Inhibitor, Kazal Pancreatic ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Autorzy:
Nagel F; Biophysical Chemistry, Institute of Biochemistry, University of Greifswald, 17489 Greifswald, Germany.
Palm GJ; Synthetic and Structural Biochemistry, Institute of Biochemistry, University of Greifswald, 17489 Greifswald, Germany.
Geist N; Biophysical Chemistry, Institute of Biochemistry, University of Greifswald, 17489 Greifswald, Germany.
McDonnell TCR; Biochemical Engineering Department, University College London, Bernard Katz, London WC1E 6BT, UK.
Susemihl A; Biophysical Chemistry, Institute of Biochemistry, University of Greifswald, 17489 Greifswald, Germany.; Department of Hematology and Oncology, Internal Medicine C, University of Greifswald, 17489 Greifswald, Germany.
Girbardt B; Synthetic and Structural Biochemistry, Institute of Biochemistry, University of Greifswald, 17489 Greifswald, Germany.
Mayerle J; Department of Medicine II, University Hospital Munich, Ludwig-Maximillian University Munich, 81377 Munich, Germany.
Lerch MM; Department of Medicine A, University Medicine Greifswald, 17489 Greifswald, Germany.
Lammers M; Synthetic and Structural Biochemistry, Institute of Biochemistry, University of Greifswald, 17489 Greifswald, Germany.
Delcea M; Biophysical Chemistry, Institute of Biochemistry, University of Greifswald, 17489 Greifswald, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Mar 23; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 23.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatitis, Chronic*/genetics
Trypsin Inhibitor, Kazal Pancreatic*/genetics
Escherichia coli ; Genetic Predisposition to Disease ; Humans ; Mutation ; Trypsin/genetics
Czasopismo naukowe
Tytuł:
High SPINK1 Expression Predicts Poor Prognosis and Promotes Cell Proliferation and Metastasis of Hepatocellular Carcinoma.
Autorzy:
Huang K; Department of Hepatic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Xie W; Department of Hepatic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Wang S; Department of Hepatic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Li Q; Department of Hepatic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Wei X; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Chen B; Department of Hepatic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Hua Y; Department of Hepatic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Li S; Department of Hepatic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Peng B; Department of Hepatic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Shen S; Department of Hepatic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
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Źródło:
Journal of investigative surgery : the official journal of the Academy of Surgical Research [J Invest Surg] 2021 Sep; Vol. 34 (9), pp. 1011-1020. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Liver Neoplasms*/genetics
Trypsin Inhibitor, Kazal Pancreatic*/genetics
Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Humans ; Prognosis
Czasopismo naukowe
Tytuł:
Gastrobodies are engineered antibody mimetics resilient to pepsin and hydrochloric acid.
Autorzy:
Wicke N; Department of Biochemistry, University of Oxford, Oxford, UK.
Bedford MR; AB Vista, Woodstock Court, Marlborough, UK.
Howarth M; Department of Biochemistry, University of Oxford, Oxford, UK. .
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Źródło:
Communications biology [Commun Biol] 2021 Aug 11; Vol. 4 (1), pp. 960. Date of Electronic Publication: 2021 Aug 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies/*pharmacology
Biomimetic Materials/*chemistry
Clostridioides difficile/*physiology
Hydrochloric Acid/*pharmacology
Pepsin A/*pharmacology
Trypsin Inhibitor, Kunitz Soybean/*chemistry
Animals ; Antibodies/chemistry ; Biomimetic Materials/pharmacology ; Chickens ; Female ; Mice ; Mice, Inbred BALB C ; Trypsin Inhibitor, Kunitz Soybean/pharmacology
Czasopismo naukowe
Tytuł:
Inhibitory effect of Bowman-Birk protease inhibitor on autophagy in MDAMB231 breast cancer cell line.
Autorzy:
Kyani S; Department of Biology, Faculty of Science, Razi University, Kermanshah, Iran.
Akrami H; Department of Biology, Faculty of Science, Razi University, Kermanshah, Iran.
Mostafaei A; Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Akbari S; Department of Biology, Faculty of Science, Razi University, Kermanshah, Iran.
Salehi Z; Department of Biology, Faculty of Science, Razi University, Kermanshah, Iran.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2021 Apr-Jun; Vol. 17 (2), pp. 504-509.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy/*drug effects
Breast Neoplasms/*drug therapy
Trypsin Inhibitor, Bowman-Birk Soybean/*pharmacology
Apoptosis/drug effects ; Breast Neoplasms/pathology ; Cell Cycle ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; Female ; Humans ; Trypsin Inhibitor, Bowman-Birk Soybean/isolation & purification ; Trypsin Inhibitor, Bowman-Birk Soybean/therapeutic use
Czasopismo naukowe
Tytuł:
Development of Breeder-Friendly KASP Markers for Low Concentration of Kunitz Trypsin Inhibitor in Soybean Seeds.
Autorzy:
Rosso ML; School of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.
Shang C; School of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.
Song Q; Beltsville Agricultural Research Center, Soybean Genomics and Improvement Laboratory, USDA-ARS, Beltsville, MD 20705, USA.
Escamilla D; Department of Agronomy, Purdue University, West Lafayette, IN 47907, USA.
Gillenwater J; Department of Crop and Soil Sciences, North Carolina State University, Raleigh, NC 27695, USA.
Zhang B; School of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 06; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 06.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Genes, Plant*
Plant Breeding*
Polymorphism, Single Nucleotide*
Quantitative Trait Loci*
Polymerase Chain Reaction/*methods
Seeds/*enzymology
Glycine max/*genetics
Trypsin Inhibitor, Kunitz Soybean/*genetics
Alleles ; Chromatography, High Pressure Liquid/methods ; DNA, Plant/analysis ; DNA, Plant/genetics ; Genetic Linkage ; Phenotype ; Plant Leaves/chemistry ; Glycine max/enzymology ; Trypsin Inhibitor, Kunitz Soybean/analysis
Czasopismo naukowe
Tytuł:
Extensive structural variation in the Bowman-Birk inhibitor family in common wheat (Triticum aestivum L.).
Autorzy:
Xie Y; Department of Soil and Crop Sciences, Colorado State University, Fort Collins, CO, 80523, USA.
Ravet K; Department of Soil and Crop Sciences, Colorado State University, Fort Collins, CO, 80523, USA.
Pearce S; Department of Soil and Crop Sciences, Colorado State University, Fort Collins, CO, 80523, USA. .
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Źródło:
BMC genomics [BMC Genomics] 2021 Mar 25; Vol. 22 (1), pp. 218. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Oryza*
Trypsin Inhibitor, Bowman-Birk Soybean*/genetics
Plant Breeding ; Stress, Physiological ; Triticum/genetics
Czasopismo naukowe

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