Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Tryptophan Hydroxylase"" wg kryterium: Temat


Tytuł :
Reduction of Tryptophan Hydroxylase Expression in the Brain of Medaka Fish After Repeated Heat Stress.
Autorzy :
Shimomura Y; Department of Life Science, Faculty of Science and Technology, Kindai University, Higashiosaka, Osaka 577-8502, Japan.
Inahata M; Department of Life Science, Faculty of Science and Technology, Kindai University, Higashiosaka, Osaka 577-8502, Japan.
Komori M; Department of Life Science, Faculty of Science and Technology, Kindai University, Higashiosaka, Osaka 577-8502, Japan.
Kagawa N; Department of Life Science, Faculty of Science and Technology, Kindai University, Higashiosaka, Osaka 577-8502, Japan, .
Pokaż więcej
Źródło :
Zoological Science [Zoolog Sci] 2019 Jun 01; Vol. 36 (3), pp. 223-230.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Zoological Society of Japan Country of Publication: Japan NLM ID: 8702287 Publication Model: Print Cited Medium: Internet ISSN: 0289-0003 (Print) Linking ISSN: 02890003 NLM ISO Abbreviation: Zool. Sci.
MeSH Terms :
Heat-Shock Response*
Brain/*enzymology
Oryzias/*metabolism
Tryptophan Hydroxylase/*metabolism
Animals ; Female ; Gene Expression Regulation, Enzymologic ; Male ; Real-Time Polymerase Chain Reaction ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł :
Serotonergic neurotransmission manipulation for the understanding of brain development and function: Learning from Tph2 genetic models.
Autorzy :
Pratelli M; Neurobiology Section, Division of Biological Sciences, University of California San Diego, La Jolla, 92093, California, USA.
Pasqualetti M; Department of Biology, Unit of Cell and Developmental Biology, University of Pisa, Pisa, 56127, Italy; Istituto Italiano di Tecnologia, Center for Neuroscience and Cognitive Systems @UniTn, Rovereto, 38068, Italy. Electronic address: .
Pokaż więcej
Źródło :
Biochimie [Biochimie] 2019 Jun; Vol. 161, pp. 3-14. Date of Electronic Publication: 2018 Dec 01.
Typ publikacji :
Journal Article; Review
Journal Info :
Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 1264604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1638-6183 (Electronic) Linking ISSN: 03009084 NLM ISO Abbreviation: Biochimie Subsets: MEDLINE
MeSH Terms :
Models, Genetic*
Synaptic Transmission*
Brain/*growth & development
Receptors, Serotonin/*metabolism
Serotonin/*metabolism
Tryptophan Hydroxylase/*metabolism
Animals ; Brain/metabolism ; Humans ; Polymorphism, Single Nucleotide ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł :
Expression Analysis of Serotonin Receptors, Serotonin Transporter and l-Amino Acid Decarboxylase in the Mouse Sphenopalatine Ganglion by RT-PCR, Northern Blot Analysis and In Situ Hybridization.
Autorzy :
Ishida Y; Division of Anatomy and Cell Biology, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyagino-ku, Sendai 983-8536, Japan; Department of Neuroscience and Cell Biology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan; Division of Otorhinolaryngology, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyagino-ku, Sendai 983-8536, Japan. Electronic address: .
Sugiura Y; Department of Neuroscience and Cell Biology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Magome T; Department of medicine for Sports and Performing Arts, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Kamakura T; Department of Neuroscience and Cell Biology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan; Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Takimoto Y; Department of Neuroscience and Cell Biology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan; Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Hanada Y; Department of Neuroscience and Cell Biology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan; Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Kitayama K; Department of Neuroscience and Cell Biology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Nakamura Y; Department of Neuroscience and Cell Biology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Shimada S; Department of Neuroscience and Cell Biology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Ohta N; Division of Otorhinolaryngology, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyagino-ku, Sendai 983-8536, Japan.
Naono-Nakayama R; Division of Anatomy and Cell Biology, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyagino-ku, Sendai 983-8536, Japan.
Kamijo K; Division of Anatomy and Cell Biology, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyagino-ku, Sendai 983-8536, Japan.
Pokaż więcej
Źródło :
Neuroscience [Neuroscience] 2019 Jul 15; Vol. 411, pp. 23-36. Date of Electronic Publication: 2019 May 23.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE
MeSH Terms :
Ganglia, Parasympathetic/*metabolism
Neurons/*metabolism
Receptors, Serotonin/*metabolism
Serotonin Plasma Membrane Transport Proteins/*metabolism
Tryptophan Hydroxylase/*metabolism
Animals ; Blotting, Northern ; In Situ Hybridization ; Male ; Mice ; Receptors, Serotonin/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Serotonin Plasma Membrane Transport Proteins/genetics ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł :
Effect of photoperiodic alterations on depression-like behavior and the brain serotonin system in mice genetically different in tryptophan hydroxylase 2 activity.
Autorzy :
Bazhenova EY; Department of Genetic Models of Neurological Disorders, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk, 630090, Russia. Electronic address: .
Fursenko DV; Department of Genetic Models of Neurological Disorders, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk, 630090, Russia.
Kulikova EA; Laboratory of Behavioral Neurogenomics, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk, 630090, Russia.
Khotskin NV; Department of Genetic Models of Neurological Disorders, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk, 630090, Russia.
Sinyakova NA; Department of Genetic Models of Neurological Disorders, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk, 630090, Russia.
Kulikov AA; Department of Genetic Models of Neurological Disorders, Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk, 630090, Russia.
Pokaż więcej
Źródło :
Neuroscience Letters [Neurosci Lett] 2019 Apr 23; Vol. 699, pp. 91-96. Date of Electronic Publication: 2019 Jan 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7972 (Electronic) Linking ISSN: 03043940 NLM ISO Abbreviation: Neurosci. Lett. Subsets: MEDLINE
MeSH Terms :
Photoperiod*
Depression/*physiopathology
Serotonin/*metabolism
Tryptophan Hydroxylase/*genetics
Animals ; Depression/genetics ; Exploratory Behavior/physiology ; Hippocampus/metabolism ; Hydroxyindoleacetic Acid/metabolism ; Immobility Response, Tonic/physiology ; Male ; Mesencephalon/metabolism ; Mice ; Motor Activity/physiology ; Polymorphism, Single Nucleotide ; Receptor, Serotonin, 5-HT2A/biosynthesis ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł :
Molecular Evolution of Tryptophan Hydroxylases in Vertebrates: A Comparative Genomic Survey.
Autorzy :
Xu J; School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu 069-8501, Japan. .
Li Y; BGI-Shenzhen, Shenzhen 518083, China. .; Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Academy of Marine Sciences, BGI Marine, BGI, Shenzhen 518083, China. .
Lv Y; Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Academy of Marine Sciences, BGI Marine, BGI, Shenzhen 518083, China. .; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen 518083, China. .
Bian C; Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Academy of Marine Sciences, BGI Marine, BGI, Shenzhen 518083, China. .
You X; Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Academy of Marine Sciences, BGI Marine, BGI, Shenzhen 518083, China. .; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen 518083, China. .
Endoh D; School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu 069-8501, Japan. .
Teraoka H; School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu 069-8501, Japan. .
Shi Q; BGI-Shenzhen, Shenzhen 518083, China. .; Shenzhen Key Lab of Marine Genomics, Guangdong Provincial Key Lab of Molecular Breeding in Marine Economic Animals, BGI Academy of Marine Sciences, BGI Marine, BGI, Shenzhen 518083, China. .; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen 518083, China. .
Pokaż więcej
Źródło :
Genes [Genes (Basel)] 2019 Mar 08; Vol. 10 (3). Date of Electronic Publication: 2019 Mar 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Print ISSN: 2073-4425 (Print) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE
MeSH Terms :
Evolution, Molecular*
Tryptophan Hydroxylase/*genetics
Animals ; Chickens ; Humans ; Protein Conformation ; Selection, Genetic ; Tryptophan Hydroxylase/chemistry ; Turtles ; Xenopus ; Zebrafish
Czasopismo naukowe
Tytuł :
The journey from gene knockout to clinical medicine: telotristat and sotagliflozin.
Autorzy :
Rendell MS; Association of Diabetes Investigators, Omaha, NE 68131, USA, .; Rose Salter Medical Research Foundation, Newport Coast, CA 92657, USA, .
Pokaż więcej
Źródło :
Drug Design, Development And Therapy [Drug Des Devel Ther] 2019 Mar 06; Vol. 13, pp. 817-824. Date of Electronic Publication: 20190306 (Print Publication: 2019).
Typ publikacji :
Journal Article; Review
Journal Info :
Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther
MeSH Terms :
Gene Knockout Techniques*
Enzyme Inhibitors/*pharmacology
Glycosides/*pharmacology
Hypoglycemic Agents/*pharmacology
Phenylalanine/*analogs & derivatives
Pyrimidines/*pharmacology
Sodium-Glucose Transporter 1/*antagonists & inhibitors
Sodium-Glucose Transporter 2/*metabolism
Tryptophan Hydroxylase/*antagonists & inhibitors
Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 1/metabolism ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Glucose/metabolism ; Humans ; Phenylalanine/pharmacology ; Serotonin/biosynthesis ; Serotonin/metabolism ; Sodium-Glucose Transporter 1/genetics ; Sodium-Glucose Transporter 1/metabolism ; Sodium-Glucose Transporter 2/genetics ; Tryptophan Hydroxylase/genetics ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł :
Tryptophan hydroxylase-2 polymorphism is associated with white matter integrity in first-episode, medication-naïve major depressive disorder patients.
Autorzy :
Ping L; Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang RD, Kunming 650032, Kunming, Yunnan, China.
Xu J; Department of Rheumatology and Immunology, First Affiliated Hospital of Kunming Medical Unversity, Kunming, Yunnan, China.
Zhou C; Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang RD, Kunming 650032, Kunming, Yunnan, China.
Lu J; Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang RD, Kunming 650032, Kunming, Yunnan, China.
Lu Y; Imaging Center, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Shen Z; Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang RD, Kunming 650032, Kunming, Yunnan, China.
Jiang L; Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang RD, Kunming 650032, Kunming, Yunnan, China.
Dai N; Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang RD, Kunming 650032, Kunming, Yunnan, China.
Xu X; Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang RD, Kunming 650032, Kunming, Yunnan, China.
Cheng Y; Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang RD, Kunming 650032, Kunming, Yunnan, China. Electronic address: .
Pokaż więcej
Źródło :
Psychiatry Research. Neuroimaging [Psychiatry Res Neuroimaging] 2019 Apr 30; Vol. 286, pp. 4-10. Date of Electronic Publication: 2019 Feb 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101723001 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7506 (Electronic) Linking ISSN: 09254927 NLM ISO Abbreviation: Psychiatry Res Neuroimaging Subsets: MEDLINE
MeSH Terms :
Corpus Callosum/*diagnostic imaging
Depressive Disorder, Major/*diagnostic imaging
Depressive Disorder, Major/*genetics
Polymorphism, Single Nucleotide/*genetics
Tryptophan Hydroxylase/*genetics
White Matter/*diagnostic imaging
Adult ; Corpus Callosum/enzymology ; Depressive Disorder, Major/enzymology ; Diffusion Tensor Imaging/methods ; Female ; Humans ; Internal Capsule/diagnostic imaging ; Internal Capsule/enzymology ; Male ; Middle Aged ; Tryptophan Hydroxylase/metabolism ; White Matter/enzymology ; Young Adult
Czasopismo naukowe
Tytuł :
Antidepressant mechanisms of venlafaxine involving increasing histone acetylation and modulating tyrosine hydroxylase and tryptophan hydroxylase expression in hippocampus of depressive rats.
Autorzy :
Qiao M; Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University.
Jiang QS; Department of Pharmacology, School of Pharmacy of Chongqing Medical University, Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing, China.
Liu YJ; Department of Pharmacology, School of Pharmacy of Chongqing Medical University, Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing, China.
Hu XY; Department of Pharmacology, School of Pharmacy of Chongqing Medical University, Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing, China.
Wang LJ; Department of Pharmacology, School of Pharmacy of Chongqing Medical University, Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing, China.
Zhou QX; Department of Pharmacology, School of Pharmacy of Chongqing Medical University, Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing, China.
Qiu HM; Department of Pharmacology, School of Pharmacy of Chongqing Medical University, Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing, China.
Pokaż więcej
Źródło :
Neuroreport [Neuroreport] 2019 Mar 06; Vol. 30 (4), pp. 255-261.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9100935 Publication Model: Print Cited Medium: Internet ISSN: 1473-558X (Electronic) Linking ISSN: 09594965 NLM ISO Abbreviation: Neuroreport Subsets: MEDLINE
MeSH Terms :
Antidepressive Agents/*pharmacology
Hippocampus/*drug effects
Tryptophan Hydroxylase/*drug effects
Tyrosine 3-Monooxygenase/*drug effects
Venlafaxine Hydrochloride/*pharmacology
Acetylation/drug effects ; Animals ; Depression/metabolism ; Hippocampus/metabolism ; Histones/drug effects ; Histones/metabolism ; Male ; Rats ; Rats, Sprague-Dawley ; Tryptophan Hydroxylase/metabolism ; Tyrosine 3-Monooxygenase/metabolism
Czasopismo naukowe
Tytuł :
Absence of Stress Response in Dorsal Raphe Nucleus in Modulator of Apoptosis 1-Deficient Mice.
Autorzy :
Zhao H; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 16, Medical Drive, #04-01, Singapore, 117600, Singapore.
Mohamed NE; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 16, Medical Drive, #04-01, Singapore, 117600, Singapore.
Chan SJ; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 16, Medical Drive, #04-01, Singapore, 117600, Singapore.; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.; Institute of Medical Biology, Glycotherapeutics Group, 8A Biomedical Grove, #06-06 Immunos, A*STAR, Singapore, 138648, Singapore.
Tan CT; Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore.
Tao R; Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore.
Yu VC; Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore.
Wong PT; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 16, Medical Drive, #04-01, Singapore, 117600, Singapore. .
Pokaż więcej
Źródło :
Molecular Neurobiology [Mol Neurobiol] 2019 Mar; Vol. 56 (3), pp. 2185-2201. Date of Electronic Publication: 2018 Jul 12.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol. Neurobiol. Subsets: MEDLINE
MeSH Terms :
Adaptor Proteins, Signal Transducing/*metabolism
Apoptosis Regulatory Proteins/*metabolism
Brain-Derived Neurotrophic Factor/*metabolism
Dorsal Raphe Nucleus/*metabolism
Stress, Physiological/*physiology
Stress, Psychological/*metabolism
Tryptophan Hydroxylase/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Animals ; Apoptosis Regulatory Proteins/genetics ; Behavior, Animal/physiology ; Brain-Derived Neurotrophic Factor/genetics ; Depression/genetics ; Depression/metabolism ; Down-Regulation ; Mice ; Mice, Knockout ; Stress, Psychological/genetics ; Swimming ; Tryptophan Hydroxylase/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Dissociation between hypothermia and neurotoxicity caused by mephedrone and methcathinone in TPH2 knockout mice.
Autorzy :
Anneken JH; Research & Development Service, John D. Dingell VA Medical Center, R&D Service (11R), 4646 John R, Detroit, MI, 48201, USA.; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Angoa-Perez M; Research & Development Service, John D. Dingell VA Medical Center, R&D Service (11R), 4646 John R, Detroit, MI, 48201, USA.; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Sati GC; Department of Chemistry, Wayne State University, Detroit, MI, 48201, USA.
Crich D; Department of Chemistry, Wayne State University, Detroit, MI, 48201, USA.
Kuhn DM; Research & Development Service, John D. Dingell VA Medical Center, R&D Service (11R), 4646 John R, Detroit, MI, 48201, USA. .; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, 48201, USA. .
Pokaż więcej
Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2019 Mar; Vol. 236 (3), pp. 1097-1106. Date of Electronic Publication: 2018 Aug 03.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl.)
MeSH Terms :
Hypothermia/*metabolism
Methamphetamine/*analogs & derivatives
Neurotoxicity Syndromes/*metabolism
Propiophenones/*toxicity
Street Drugs/*toxicity
Tryptophan Hydroxylase/*deficiency
Animals ; Female ; Hypothermia/chemically induced ; Hypothermia/physiopathology ; Methamphetamine/toxicity ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nerve Endings/drug effects ; Nerve Endings/metabolism ; Neurotoxicity Syndromes/etiology ; Neurotoxicity Syndromes/physiopathology ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł :
Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice.
Autorzy :
Russo AM; School of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia.
Lawther AJ; School of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia.
Prior BM; School of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia.
Isbel L; School of Molecular Sciences, La Trobe University, Melbourne, VIC, 3086, Australia.
Somers WG; Olga Tennison Autism Research Centre, La Trobe University, Melbourne, VIC, 3086, Australia.
Lesku JA; School of Life Sciences, La Trobe University, Melbourne, VIC, 3086, Australia.
Richdale AL; School of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia; Olga Tennison Autism Research Centre, La Trobe University, Melbourne, VIC, 3086, Australia.
Dissanayake C; School of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia; Olga Tennison Autism Research Centre, La Trobe University, Melbourne, VIC, 3086, Australia.
Kent S; School of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia.
Lowry CA; Department of Integrative Physiology and Center for Neuroscience, University of Colorado Boulder, Boulder, CO 80309, USA.
Hale MW; School of Psychology and Public Health, La Trobe University, Melbourne, VIC, 3086, Australia. Electronic address: .
Pokaż więcej
Źródło :
Behavioural Brain Research [Behav Brain Res] 2019 Feb 01; Vol. 359, pp. 918-926. Date of Electronic Publication: 2018 Jun 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info :
Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav. Brain Res. Subsets: MEDLINE
MeSH Terms :
Social Behavior*
Anxiety/*metabolism
Raphe Nuclei/*metabolism
Tryptophan Hydroxylase/*metabolism
Age Factors ; Analysis of Variance ; Animals ; Animals, Newborn ; Anxiety/drug therapy ; Enzyme Inhibitors/pharmacology ; Gene Expression Regulation/drug effects ; Genotype ; Humans ; Hydrazines/therapeutic use ; Male ; Maze Learning/drug effects ; Maze Learning/physiology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Species Specificity ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł :
Physiological dosages of estradiol and diarylpropionitrile decrease depressive behavior and increase tryptophan hydroxylase expression in the dorsal raphe nucleus of rats subjected to the forced swim test.
Autorzy :
Yang F; Shanghai Mental Health Center.
Cheung A; Department of Neurobiology, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Tao J; Shanghai Mental Health Center.
Zhao N; Shanghai Pudong New Area Mental Health Center, Shanghai, People's Republic of China.
Wan W; Department of Neurology, Renji Hospital, Shanghai Jiao Tong University School of Medicine.
Sheng J; Shanghai Mental Health Center.
Pokaż więcej
Źródło :
Neuroreport [Neuroreport] 2019 Jan 16; Vol. 30 (2), pp. 66-70.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9100935 Publication Model: Print Cited Medium: Internet ISSN: 1473-558X (Electronic) Linking ISSN: 09594965 NLM ISO Abbreviation: Neuroreport Subsets: MEDLINE
MeSH Terms :
Depression/*drug therapy
Depression/*enzymology
Dorsal Raphe Nucleus/*enzymology
Estradiol/*administration & dosage
Nitriles/*administration & dosage
Propionates/*administration & dosage
Tryptophan Hydroxylase/*biosynthesis
Animals ; Antidepressive Agents/administration & dosage ; Depression/psychology ; Dorsal Raphe Nucleus/drug effects ; Estradiol/physiology ; Female ; Gene Expression Regulation, Enzymologic ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Swimming/psychology ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł :
Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model.
Autorzy :
Kim H; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Kim YG; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Choi W; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Moon JH; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Hwang I; Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Kim K; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Yadav VK; Department of Genetics and Development, Columbia University Medical Center, New York, NY, 10032, USA.
Karsenty G; Department of Genetics and Development, Columbia University Medical Center, New York, NY, 10032, USA.
Jeong JS; Center for Bioanalysis, Division of Chemical and Medical Metrology, Korea Research Institute of Standards and Science, Daejeon, 34113, Republic of Korea. .
Kim H; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea. .; Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea. .
Pokaż więcej
Źródło :
Scientific Reports [Sci Rep] 2018 Dec 05; Vol. 8 (1), pp. 17642. Date of Electronic Publication: 2018 Dec 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
MeSH Terms :
Gene Knockout Techniques/*methods
Tryptophan Hydroxylase/*genetics
Animals ; Gene Deletion ; Insulin-Secreting Cells/metabolism ; Intestinal Mucosa/metabolism ; Mice ; Mice, Knockout ; Models, Animal ; Serotonin/metabolism ; Tryptophan Hydroxylase/metabolism
Czasopismo naukowe
Tytuł :
Antidepressant effect of venlafaxine in chronic unpredictable stress: Evidence of the involvement of key enzymes responsible for monoamine neurotransmitter synthesis and metabolism.
Autorzy :
Liu, Dan (AUTHOR)
Hu, Xiao-Ya (AUTHOR)
Xia, Hai-Jian (AUTHOR)
Wang, Li-Jia (AUTHOR)
Shi, Ping (AUTHOR)
Chen, Xiang-Pan (AUTHOR)
Zhou, Qi-Xin (AUTHOR)
Pokaż więcej
Źródło :
Molecular Medicine Reports. Sep2019, Vol. 20 Issue 3, p2954-2962. 9p.
Czasopismo naukowe
Tytuł :
Serotonin signals through a gut-liver axis to regulate hepatic steatosis.
Autorzy :
Choi W; Graduate School of Medical Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea.
Namkung J; Graduate School of Medical Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea.; Department of Biochemistry, Yonsei University Wonju College of Medicine, Wonju, 26426, Republic of Korea.
Hwang I; Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, 34141, Republic of Korea.
Kim H; Graduate School of Medical Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea.
Lim A; Graduate School of Medical Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea.
Park HJ; Department of Internal Medicine, Yonsei University College of Medicine, Yonsei Liver Center, Severance Hospital, Seoul, 03722, Republic of Korea.
Lee HW; Department of Internal Medicine, Yonsei University College of Medicine, Yonsei Liver Center, Severance Hospital, Seoul, 03722, Republic of Korea.
Han KH; Department of Internal Medicine, Yonsei University College of Medicine, Yonsei Liver Center, Severance Hospital, Seoul, 03722, Republic of Korea.
Park S; Graduate School of Medical Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea.
Jeong JS; Center for Bioanalysis, Division of Metrology for Quality of Life, Korea Research Institute of Standards and Science, Daejeon, 34113, Republic of Korea.
Bang G; Biomedical Omics Group, Korea Basic Science Institute, Chungbuk, 28119, Republic of Korea.
Kim YH; Biomedical Omics Group, Korea Basic Science Institute, Chungbuk, 28119, Republic of Korea.
Yadav VK; Department of Genetics and Development, Columbia University Medical Center, New York, NY, 10032, USA.
Karsenty G; Department of Genetics and Development, Columbia University Medical Center, New York, NY, 10032, USA.
Ju YS; Graduate School of Medical Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea.
Choi C; Department of Pathology, Chonnam National University Medical School, Gwangju, 61469, Republic of Korea.
Suh JM; Graduate School of Medical Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea.; Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, 34141, Republic of Korea.
Park JY; Department of Internal Medicine, Yonsei University College of Medicine, Yonsei Liver Center, Severance Hospital, Seoul, 03722, Republic of Korea. .
Park S; Graduate School of Medical Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea. .; Department of Biochemistry, College of Medicine, Catholic Kwandong University, Gangneung, 25601, Republic of Korea. .
Kim H; Graduate School of Medical Science and Engineering, KAIST, Daejeon, 34141, Republic of Korea. .; Biomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, 34141, Republic of Korea. .; KAIST Institute for the BioCentury, KAIST, Daejeon, 34141, Republic of Korea. .
Pokaż więcej
Źródło :
Nature Communications [Nat Commun] 2018 Nov 16; Vol. 9 (1), pp. 4824. Date of Electronic Publication: 2018 Nov 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
MeSH Terms :
Intestinal Mucosa/*metabolism
Liver/*metabolism
Non-alcoholic Fatty Liver Disease/*genetics
Receptor, Serotonin, 5-HT2A/*genetics
Serotonin/*metabolism
Tryptophan Hydroxylase/*genetics
Animals ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Hypolipidemic Agents/pharmacology ; Insulin Resistance ; Intestinal Mucosa/pathology ; Lipid Metabolism ; Liver/pathology ; Male ; Mice ; Mice, Knockout ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/pathology ; Non-alcoholic Fatty Liver Disease/prevention & control ; Receptor, Serotonin, 5-HT2A/deficiency ; Serotonin Antagonists/pharmacology ; Signal Transduction ; Succinates/pharmacology ; Tryptophan Hydroxylase/deficiency
Czasopismo naukowe
Tytuł :
The Relationship Between Tryptophan Hydroxylase-2 Gene with Primary Insomnia and Depressive Symptoms in the Han Chinese Population
Autorzy :
Mei F; Department of Medical Psychology, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
Wu Y; Department of Neurology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
Wu J; Department of Neurology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
Pokaż więcej
Źródło :
Balkan Medical Journal [Balkan Med J] 2018 Nov 15; Vol. 35 (6), pp. 412-416. Date of Electronic Publication: 2018 Jun 28.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Galenos Publishing House Country of Publication: Turkey NLM ID: 101571817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2146-3131 (Electronic) Linking ISSN: 21463123 NLM ISO Abbreviation: Balkan Med J Subsets: MEDLINE
MeSH Terms :
Asian Continental Ancestry Group/*genetics
Sleep Initiation and Maintenance Disorders/*genetics
Tryptophan Hydroxylase/*analysis
Adult ; Case-Control Studies ; China ; Depression/blood ; Depression/etiology ; Depression/genetics ; Female ; Genetic Predisposition to Disease ; Humans ; Male ; Middle Aged ; Polysomnography/methods ; Psychometrics/instrumentation ; Psychometrics/methods ; Sleep Initiation and Maintenance Disorders/blood ; Sleep Initiation and Maintenance Disorders/complications ; Tryptophan Hydroxylase/blood
Czasopismo naukowe
Tytuł :
Differential anxiety-related behaviours and brain activation in Tph2-deficient female mice exposed to adverse early environment.
Autorzy :
Auth CS; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, Department of Psychiatry, University of Würzburg, Würzburg, Germany.
Weidner MT; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, Department of Psychiatry, University of Würzburg, Würzburg, Germany; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands. Electronic address: .
Popp S; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, Department of Psychiatry, University of Würzburg, Würzburg, Germany.
Strekalova T; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, Department of Psychiatry, University of Würzburg, Würzburg, Germany; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands; Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Schmitt-Böhrer AG; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, Department of Psychiatry, University of Würzburg, Würzburg, Germany.
van den Hove D; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, Department of Psychiatry, University of Würzburg, Würzburg, Germany; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
Lesch KP; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, Department of Psychiatry, University of Würzburg, Würzburg, Germany; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands; Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Waider J; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, Department of Psychiatry, University of Würzburg, Würzburg, Germany.
Pokaż więcej
Źródło :
European Neuropsychopharmacology: The Journal Of The European College Of Neuropsychopharmacology [Eur Neuropsychopharmacol] 2018 Nov; Vol. 28 (11), pp. 1270-1283. Date of Electronic Publication: 2018 Aug 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9111390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7862 (Electronic) Linking ISSN: 0924977X NLM ISO Abbreviation: Eur Neuropsychopharmacol Subsets: MEDLINE
MeSH Terms :
Maternal Deprivation*
Anxiety/*physiopathology
Tryptophan Hydroxylase/*physiology
Amygdala/physiology ; Animals ; Behavior, Animal/physiology ; Brain/metabolism ; Female ; Mice ; Mice, Knockout ; Paraventricular Hypothalamic Nucleus/physiology ; Periaqueductal Gray/physiology ; Proto-Oncogene Proteins c-fos/metabolism ; Serotonin/deficiency ; Serotonin/physiology ; Tryptophan Hydroxylase/genetics
Czasopismo naukowe
Tytuł :
Metabolic pathway engineering for high-level production of 5-hydroxytryptophan in Escherichia coli.
Autorzy :
Wang H; Key Laboratory of Biomass Chemical Engineering (Education Ministry), College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China; Institute of Biological Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Liu W; Institute of Biological Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Shi F; Shandong Institute for Food and Drug Control, Jinan 250101, China.
Huang L; Institute of Biological Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Lian J; Key Laboratory of Biomass Chemical Engineering (Education Ministry), College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China; Institute of Biological Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China. Electronic address: .
Qu L; Key Laboratory of Biomass Chemical Engineering (Education Ministry), College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Cai J; Institute of Biological Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Xu Z; Key Laboratory of Biomass Chemical Engineering (Education Ministry), College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China; Institute of Biological Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China; Shandong Institute for Food and Drug Control, Jinan 250101, China. Electronic address: .
Pokaż więcej
Źródło :
Metabolic Engineering [Metab Eng] 2018 Jul; Vol. 48, pp. 279-287. Date of Electronic Publication: 2018 Jun 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Academic Press Country of Publication: Belgium NLM ID: 9815657 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7184 (Electronic) Linking ISSN: 10967176 NLM ISO Abbreviation: Metab. Eng. Subsets: MEDLINE
MeSH Terms :
5-Hydroxytryptophan*/biosynthesis
5-Hydroxytryptophan*/genetics
Escherichia coli*/genetics
Escherichia coli*/metabolism
Metabolic Engineering*
Tryptophan Hydroxylase*/biosynthesis
Tryptophan Hydroxylase*/genetics
Biopterin/*analogs & derivatives
Biopterin/biosynthesis ; Biopterin/genetics ; Humans
Czasopismo naukowe
Tytuł :
Uncovering pharmacological mechanisms of Zhi-Zi-Hou-Po decoction in chronic unpredictable mild stress induced rats through pharmacokinetics, monoamine neurotransmitter and neurogenesis.
Autorzy :
Xing H; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China.
Zhang X; 13 Ward of General Surgery Department, Da Qing Long Nan Hospital, Daqing, China.
Xing N; Department of Pharmacy, Harbin Traditional Chinese Medicine Hospital, Harbin, China.
Qu H; Harbin Normal University, Harbin, China.
Zhang K; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China. Electronic address: .
Pokaż więcej
Źródło :
Journal Of Ethnopharmacology [J Ethnopharmacol] 2019 Oct 28; Vol. 243, pp. 112079. Date of Electronic Publication: 2019 Jul 11.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
MeSH Terms :
Antidepressive Agents/*pharmacology
Depression/*metabolism
Drugs, Chinese Herbal/*pharmacology
Iridoids/*pharmacology
Stress, Psychological/*metabolism
Animals ; Antidepressive Agents/therapeutic use ; Biogenic Monoamines/metabolism ; Chronic Disease ; Depression/drug therapy ; Dopamine Plasma Membrane Transport Proteins/metabolism ; Drugs, Chinese Herbal/pharmacokinetics ; Drugs, Chinese Herbal/therapeutic use ; Hippocampus/drug effects ; Hippocampus/physiology ; Iridoids/pharmacokinetics ; Iridoids/therapeutic use ; Male ; Neurogenesis/drug effects ; Rats, Sprague-Dawley ; Serotonin Plasma Membrane Transport Proteins/metabolism ; Stress, Psychological/drug therapy ; Tryptophan Hydroxylase/metabolism ; Tyrosine 3-Monooxygenase/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies