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Wyszukujesz frazę ""Tsuboi, Takashi"" wg kryterium: Autor


Tytuł :
Bitter tastant quinine modulates glucagon-like peptide-1 exocytosis from clonal GLUTag enteroendocrine L cells via actin reorganization.
Autorzy :
Harada K; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo 153-8902, Japan.
Sakaguchi H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-0033, Japan.
Sada S; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo 153-8902, Japan.
Ishida R; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo 153-8902, Japan.
Hayasaka Y; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo 153-8902, Japan.
Tsuboi T; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo 153-8902, Japan; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-0033, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 Jun 07; Vol. 500 (3), pp. 723-730. Date of Electronic Publication: 2018 Apr 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis*/drug effects
Taste*
Actins/*metabolism
Enteroendocrine Cells/*metabolism
Glucagon-Like Peptide 1/*metabolism
Quinine/*pharmacology
Actin Cytoskeleton/drug effects ; Actin Cytoskeleton/metabolism ; Calcium/metabolism ; Cell Line ; Cyclic AMP/metabolism ; Enteroendocrine Cells/drug effects ; GTP-Binding Protein alpha Subunits, Gq-G11/metabolism ; Humans ; Intracellular Space/metabolism ; KATP Channels/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Integrative function of adrenaline receptors for glucagon-like peptide-1 exocytosis in enteroendocrine L cell line GLUTag.
Autorzy :
Harada K; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo 153-8902, Japan.
Kitaguchi T; Cell Signaling Group, Waseda Bioscience Research Institute in Singapore (WABIOS), 11 Biopolis Way #05-02 Helios, Singapore 138667, Singapore; Organization for University Research Initiatives, Waseda University, #304, Block 120-4, 513 Wasedatsurumaki-cho, Shinjuku-ku, Tokyo 162-0041, Japan.
Tsuboi T; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo 153-8902, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2015 May 15; Vol. 460 (4), pp. 1053-8. Date of Electronic Publication: 2015 Apr 03.
Typ publikacji :
Journal Article
MeSH Terms :
Exocytosis*
Enteroendocrine Cells/*metabolism
Epinephrine/*metabolism
Glucagon-Like Peptide 1/*metabolism
Receptors, Adrenergic/*physiology
Animals ; Base Sequence ; Calcium/metabolism ; Cell Line ; Cyclic AMP/metabolism ; DNA Primers ; Enteroendocrine Cells/cytology ; Mice ; Microscopy, Fluorescence ; Polymerase Chain Reaction ; Receptors, Adrenergic/metabolism
Czasopismo naukowe
Tytuł :
The small GTPase Cdc42 modulates the number of exocytosis-competent dense-core vesicles in PC12 cells.
Autorzy :
Sato M; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo 153-8902, Japan.
Kitaguchi T
Numano R
Ikematsu K
Kakeyama M
Murata M
Sato K
Tsuboi T
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2012 Apr 06; Vol. 420 (2), pp. 417-21. Date of Electronic Publication: 2012 Mar 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis*
Secretory Vesicles/*physiology
cdc42 GTP-Binding Protein/*physiology
Animals ; PC12 Cells ; Rats ; Secretory Vesicles/genetics ; Secretory Vesicles/ultrastructure ; cdc42 GTP-Binding Protein/genetics
Czasopismo naukowe
Tytuł :
Duration of fusion pore opening and the amount of hormone released are regulated by myosin II during kiss-and-run exocytosis.
Autorzy :
Aoki R; Department of Life Sciences, The University of Tokyo, Meguro, Japan.
Kitaguchi T
Oya M
Yanagihara Y
Sato M
Miyawaki A
Tsuboi T
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Źródło :
The Biochemical journal [Biochem J] 2010 Aug 01; Vol. 429 (3), pp. 497-504.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis*
Membrane Fusion*
Brain-Derived Neurotrophic Factor/*metabolism
Myosin Type II/*physiology
Tissue Plasminogen Activator/*metabolism
Animals ; Base Sequence ; DNA Primers ; Immunohistochemistry ; Kinetics ; Luminescent Proteins/metabolism ; Microscopy, Fluorescence ; PC12 Cells ; Rats
Czasopismo naukowe
Tytuł :
Role of the polybasic sequence in the Doc2alpha C2B domain in dense-core vesicle exocytosis in PC12 cells.
Autorzy :
Sato M; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Meguro, Tokyo, Japan.
Mori Y
Matsui T
Aoki R
Oya M
Yanagihara Y
Fukuda M
Tsuboi T
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Źródło :
Journal of neurochemistry [J Neurochem] 2010 Jul; Vol. 114 (1), pp. 171-81. Date of Electronic Publication: 2010 Apr 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis*
Calcium-Binding Proteins/*physiology
Nerve Tissue Proteins/*physiology
Secretory Vesicles/*metabolism
Amino Acid Sequence ; Animals ; Calcium-Binding Proteins/genetics ; Cell Membrane/metabolism ; Cytosol/metabolism ; Mice ; Molecular Sequence Data ; Mutation ; Nerve Tissue Proteins/genetics ; PC12 Cells ; Protein Binding ; Protein Multimerization ; Protein Structure, Tertiary ; Protein Transport ; Rats ; Synaptosomal-Associated Protein 25/genetics ; Syntaxin 1/genetics
Czasopismo naukowe
Tytuł :
Age-dependent preferential dense-core vesicle exocytosis in neuroendocrine cells revealed by newly developed monomeric fluorescent timer protein.
Autorzy :
Tsuboi T; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Meguro, Tokyo, Japan. />Kitaguchi T
Karasawa S
Fukuda M
Miyawaki A
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Źródło :
Molecular biology of the cell [Mol Biol Cell] 2010 Jan 01; Vol. 21 (1), pp. 87-94. Date of Electronic Publication: 2009 Nov 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis*
Aging/*metabolism
Luminescent Proteins/*metabolism
Neuroendocrine Cells/*cytology
Neuroendocrine Cells/*metabolism
Secretory Vesicles/*metabolism
Animals ; Gene Silencing ; Mice ; Models, Biological ; Neuropeptide Y/metabolism ; PC12 Cells ; RNA, Small Interfering/metabolism ; Rats ; Spectrometry, Fluorescence ; Time Factors ; Tissue Plasminogen Activator/metabolism ; Vesicular Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Molecular mechanism of attachment process of dense-core vesicles to the plasma membrane in neuroendocrine cells.
Autorzy :
Tsuboi T; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Meguro, Tokyo, Japan.
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Źródło :
Neuroscience research [Neurosci Res] 2009 Feb; Vol. 63 (2), pp. 83-8. Date of Electronic Publication: 2008 Nov 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Membrane/*metabolism
Exocytosis/*physiology
Neuroendocrine Cells/*ultrastructure
Secretory Vesicles/*physiology
Animals ; Secretory Vesicles/genetics ; Vesicular Transport Proteins/chemistry ; Vesicular Transport Proteins/metabolism ; rab GTP-Binding Proteins/genetics ; rab GTP-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
Imaging a target of Ca2+ signalling: dense core granule exocytosis viewed by total internal reflection fluorescence microscopy.
Autorzy :
Ravier MA; Unit of Endocrinology and Metabolism, University of Louvain Faculty of Medicine, UCL 55.30 Avenue Hippocrate 55, B-1200 Brussels, Belgium.
Tsuboi T
Rutter GA
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Źródło :
Methods (San Diego, Calif.) [Methods] 2008 Nov; Vol. 46 (3), pp. 233-8. Date of Electronic Publication: 2008 Oct 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling*
Calcium/*metabolism
Exocytosis/*physiology
Microscopy, Fluorescence/*methods
Animals ; Cell Membrane/metabolism ; Fluorescent Dyes ; Microscopy, Confocal ; Microscopy, Fluorescence/instrumentation ; PC12 Cells ; Rats
Czasopismo naukowe
Tytuł :
Synaptotagmin VII modulates the kinetics of dense-core vesicle exocytosis in PC12 cells.
Autorzy :
Tsuboi T; Fukuda Initiative Research Unit, RIKEN (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Fukuda M
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Źródło :
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2007 Apr; Vol. 12 (4), pp. 511-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis/*physiology
Secretory Vesicles/*metabolism
Synaptotagmins/*metabolism
Animals ; Calcium/metabolism ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Mutagenesis, Site-Directed ; Neuropeptide Y/genetics ; Neuropeptide Y/metabolism ; PC12 Cells ; Rats ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Synaptotagmins/genetics ; Tissue Plasminogen Activator/genetics ; Tissue Plasminogen Activator/metabolism
Czasopismo naukowe
Tytuł :
The polybasic sequence in the C2B domain of rabphilin is required for the vesicle docking step in PC12 cells.
Autorzy :
Tsuboi T; Fukuda Initiative Research Unit, RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama, Japan.
Kanno E
Fukuda M
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Źródło :
Journal of neurochemistry [J Neurochem] 2007 Feb; Vol. 100 (3), pp. 770-9. Date of Electronic Publication: 2006 Nov 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptor Proteins, Signal Transducing/*chemistry
Cell Membrane/*metabolism
Exocytosis/*physiology
Nerve Tissue Proteins/*chemistry
Neurons/*metabolism
Neurosecretion/*physiology
Secretory Vesicles/*metabolism
Vesicular Transport Proteins/*chemistry
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Amino Acid Sequence/genetics ; Animals ; Binding Sites/genetics ; COS Cells ; Chlorocebus aethiops ; Membrane Fusion/physiology ; Mutation/genetics ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; PC12 Cells ; Protein Binding/genetics ; Protein Structure, Tertiary/genetics ; Rats ; Synaptosomal-Associated Protein 25/metabolism ; Vesicular Transport Proteins/genetics ; Vesicular Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Rab3A and Rab27A cooperatively regulate the docking step of dense-core vesicle exocytosis in PC12 cells.
Autorzy :
Tsuboi T; Fukuda Initiative Research Unit, RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama, Japan.
Fukuda M
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Źródło :
Journal of cell science [J Cell Sci] 2006 Jun 01; Vol. 119 (Pt 11), pp. 2196-203. Date of Electronic Publication: 2006 May 09.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis/*physiology
rab GTP-Binding Proteins/*physiology
rab3A GTP-Binding Protein/*physiology
Animals ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Cells, Cultured ; Exocytosis/drug effects ; PC12 Cells ; RNA, Small Interfering/pharmacology ; Rats ; Secretory Vesicles/drug effects ; Secretory Vesicles/physiology ; rab GTP-Binding Proteins/antagonists & inhibitors ; rab GTP-Binding Proteins/biosynthesis ; rab27 GTP-Binding Proteins ; rab3A GTP-Binding Protein/antagonists & inhibitors ; rab3A GTP-Binding Protein/biosynthesis
Czasopismo naukowe
Tytuł :
The Slp4-a linker domain controls exocytosis through interaction with Munc18-1.syntaxin-1a complex.
Autorzy :
Tsuboi T; Fukuda Initiative Research Unit, Riken (The Institute of Physical and Chemical Research), Wako, Saitama 351-0198, Japan.
Fukuda M
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Źródło :
Molecular biology of the cell [Mol Biol Cell] 2006 May; Vol. 17 (5), pp. 2101-12. Date of Electronic Publication: 2006 Feb 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis*
Munc18 Proteins/*metabolism
Syntaxin 1/*metabolism
Transport Vesicles/*metabolism
Vesicular Transport Proteins/*chemistry
Vesicular Transport Proteins/*metabolism
Animals ; Carrier Proteins/metabolism ; Cell Membrane/metabolism ; Humans ; Membrane Fusion ; Membrane Proteins/metabolism ; PC12 Cells ; Protein Interaction Mapping ; Protein Structure, Tertiary ; RNA, Small Interfering/genetics ; RNA, Small Interfering/pharmacology ; Rats ; Vesicular Transport Proteins/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
The C2B domain of rabphilin directly interacts with SNAP-25 and regulates the docking step of dense core vesicle exocytosis in PC12 cells.
Autorzy :
Tsuboi T; Fukuda Initiative Research Unit, RIKEN (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Fukuda M
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2005 Nov 25; Vol. 280 (47), pp. 39253-9. Date of Electronic Publication: 2005 Oct 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis/*physiology
GTP-Binding Proteins/*metabolism
Nerve Tissue Proteins/*metabolism
Synaptosomal-Associated Protein 25/*metabolism
Vesicular Transport Proteins/*metabolism
Animals ; Binding Sites/genetics ; GTP-Binding Proteins/chemistry ; GTP-Binding Proteins/genetics ; Mice ; Nerve Tissue Proteins/chemistry ; Nerve Tissue Proteins/genetics ; PC12 Cells ; Protein Binding ; Protein Structure, Tertiary ; Rats ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Secretory Vesicles/physiology ; Synaptosomal-Associated Protein 25/genetics ; Vesicular Transport Proteins/chemistry ; Vesicular Transport Proteins/genetics ; rab GTP-Binding Proteins/genetics ; rab GTP-Binding Proteins/metabolism ; rab27 GTP-Binding Proteins
Czasopismo naukowe
Tytuł :
Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis.
Autorzy :
Tsuboi T; Henry Wellcome Laboratories for Integrated Cell Signalling and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, United Kingdom.
Ravier MA
Xie H
Ewart MA
Gould GW
Baldwin SA
Rutter GA
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2005 Jul 08; Vol. 280 (27), pp. 25565-70. Date of Electronic Publication: 2005 May 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carrier Proteins/*metabolism
Exocytosis/*physiology
Insulin/*metabolism
Islets of Langerhans/*metabolism
Animals ; Carrier Proteins/genetics ; Cell Line, Tumor ; Cell Membrane/metabolism ; Cytoplasm/metabolism ; Gene Expression ; Insulinoma ; Islets of Langerhans/cytology ; Mammals ; Membrane Proteins ; Mice ; Mutagenesis ; Secretory Vesicles/metabolism
Czasopismo naukowe
Tytuł :
Kiss and run exocytosis of dense core secretory vesicles.
Autorzy :
Rutter GA; Henry Wellcome Signalling Laboratories, Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK. />Tsuboi T
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Źródło :
Neuroreport [Neuroreport] 2004 Jan 19; Vol. 15 (1), pp. 79-81.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Exocytosis/*physiology
Secretory Vesicles/*metabolism
Animals ; Endocytosis/physiology ; Humans ; Secretory Vesicles/genetics
Czasopismo naukowe
Tytuł :
Multiple forms of "kiss-and-run" exocytosis revealed by evanescent wave microscopy.
Autorzy :
Tsuboi T; Henry Wellcome Laboratories for Integrated Cell Signalling and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, BS8 1TD, Bristol, United Kingdom.
Rutter GA
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Źródło :
Current biology : CB [Curr Biol] 2003 Apr 01; Vol. 13 (7), pp. 563-7.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium-Binding Proteins*
Exocytosis/*physiology
Islets of Langerhans/*physiology
Membrane Glycoproteins/*metabolism
Nerve Tissue Proteins/*metabolism
Humans ; Islets of Langerhans/metabolism ; Membrane Proteins/metabolism ; Microscopy, Fluorescence ; Neuropeptide Y ; Protein Tyrosine Phosphatases/metabolism ; R-SNARE Proteins ; Receptor-Like Protein Tyrosine Phosphatases, Class 8 ; Synaptotagmins
Czasopismo naukowe
Tytuł :
Water secretion associated with exocytosis in endocrine cells revealed by micro forcemetry and evanescent wave microscopy.
Autorzy :
Tsuboi T; Photon Medical Research Center, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Kikuta T
Sakurai T
Terakawa S
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Źródło :
Biophysical journal [Biophys J] 2002 Jul; Vol. 83 (1), pp. 172-83.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exocytosis*
Chromaffin Cells/*metabolism
Water/*metabolism
Acridine Orange/pharmacology ; Animals ; Cattle ; Cells, Cultured ; Chlorine/metabolism ; Coloring Agents/pharmacology ; Dose-Response Relationship, Drug ; Electrophysiology ; Hydrogen-Ion Concentration ; Immunoblotting ; Lasers ; Microscopy, Confocal ; Microscopy, Fluorescence ; Monte Carlo Method ; Potassium/metabolism ; Rats ; Signal Transduction ; Spectrometry, Fluorescence ; Time Factors
Czasopismo naukowe
Tytuł :
Neuronal calcium sensor-1 binds to regulated secretory organelles and functions in basal and stimulated exocytosis in PC12 cells.
Autorzy :
Scalettar BA; Department of Physics, Lewis and Clark College, Portland, OR 97219, USA. />Rosa P
Taverna E
Francolini M
Tsuboi T
Terakawa S
Koizumi S
Roder J
Jeromin A
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Źródło :
Journal of cell science [J Cell Sci] 2002 Jun 01; Vol. 115 (Pt 11), pp. 2399-412.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Calcium-Binding Proteins/*metabolism
Exocytosis/*physiology
Nervous System/*metabolism
Neurons/*metabolism
Neuropeptides/*metabolism
Organelles/*metabolism
Secretory Vesicles/*metabolism
Animals ; Axonal Transport/physiology ; Bacterial Proteins ; Calcium-Binding Proteins/genetics ; Growth Cones/metabolism ; Growth Cones/ultrastructure ; Immunohistochemistry ; Luminescent Proteins ; Microscopy, Electron ; Nervous System/ultrastructure ; Neuronal Calcium-Sensor Proteins ; Neurons/ultrastructure ; Neuropeptides/genetics ; Neurosecretory Systems/metabolism ; Neurosecretory Systems/ultrastructure ; Organelles/ultrastructure ; PC12 Cells ; Protein Binding/physiology ; Protein Transport/physiology ; Rats ; Recombinant Fusion Proteins ; Secretory Vesicles/ultrastructure ; Synaptic Vesicles/metabolism ; Synaptic Vesicles/ultrastructure ; Synaptophysin
Czasopismo naukowe
Tytuł :
Sweeping model of dynamin activity. Visualization of coupling between exocytosis and endocytosis under an evanescent wave microscope with green fluorescent proteins.
Autorzy :
Tsuboi T; Laboratory of Cell Imaging, Photon Medical Research Center, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Japan.
Terakawa S
Scalettar BA
Fantus C
Roder J
Jeromin A
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2002 May 03; Vol. 277 (18), pp. 15957-61. Date of Electronic Publication: 2002 Feb 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Endocytosis/*physiology
Exocytosis/*physiology
GTP Phosphohydrolases/*metabolism
Luminescent Proteins/*metabolism
Animals ; Cell Line ; Dynamin I ; Dynamins ; Electric Stimulation ; GTP Phosphohydrolases/genetics ; Genes, Reporter ; Green Fluorescent Proteins ; Microscopy, Fluorescence ; Microtubules/metabolism ; PC12 Cells ; Rats ; Recombinant Fusion Proteins/metabolism ; Transfection
Czasopismo naukowe

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