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Tytuł:
EGFR-targeted bacteriophage lambda penetrates model stromal and colorectal carcinoma tissues, is taken up into carcinoma cells, and interferes with 3-dimensional tumor formation.
Autorzy:
Huh H; School of Pharmacy, University of Waterloo, Waterloo, ON, Canada.
Chen DW; School of Pharmacy, University of Waterloo, Waterloo, ON, Canada.
Foldvari M; School of Pharmacy, University of Waterloo, Waterloo, ON, Canada.
Slavcev R; School of Pharmacy, University of Waterloo, Waterloo, ON, Canada.
Blay J; School of Pharmacy, University of Waterloo, Waterloo, ON, Canada.; Department of Pathology, Dalhousie University, Halifax, NS, Canada.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 16; Vol. 13, pp. 957233. Date of Electronic Publication: 2022 Dec 16 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacteriophage lambda*/genetics
Bacteriophage lambda*/immunology
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/immunology
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/therapy
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Carcinogenesis*/genetics
Carcinogenesis*/immunology
Humans ; Epidermal Growth Factor/genetics ; Epidermal Growth Factor/immunology ; ErbB Receptors/genetics ; ErbB Receptors/immunology
Czasopismo naukowe
Szczegóły
Tytuł:
Infiltration of LPAR5 macrophages in osteosarcoma tumor microenvironment predicts better outcomes.
Autorzy:
He Y; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhou H; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Huang X; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Qu Y; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wang Y; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Pei W; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhang R; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Chen S; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
You H; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 15; Vol. 13, pp. 909932. Date of Electronic Publication: 2022 Dec 15 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone Neoplasms*/genetics
Bone Neoplasms*/immunology
Macrophages*/immunology
Osteosarcoma*/genetics
Osteosarcoma*/immunology
Receptors, Lysophosphatidic Acid*/genetics
Receptors, Lysophosphatidic Acid*/immunology
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Humans ; Phagocytosis/genetics ; Phagocytosis/immunology ; Prognosis ; Antigen Presentation/genetics ; Antigen Presentation/immunology
Czasopismo naukowe
Szczegóły
Tytuł:
Fatty acid metabolism is related to the immune microenvironment changes of gastric cancer and RGS2 is a new tumor biomarker.
Autorzy:
Yang S; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.; The Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin, China.
Sun B; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Li W; Department of Otorhinolaryngology, Head and Neck Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Yang H; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Li N; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhang X; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 14; Vol. 13, pp. 1065927. Date of Electronic Publication: 2022 Dec 14 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers, Tumor*/genetics
Biomarkers, Tumor*/immunology
Fatty Acids*/genetics
Fatty Acids*/immunology
Fatty Acids*/metabolism
RGS Proteins*/genetics
RGS Proteins*/immunology
Stomach Neoplasms*/drug therapy
Stomach Neoplasms*/genetics
Stomach Neoplasms*/immunology
Tumor Microenvironment*/drug effects
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Humans ; Blotting, Western ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Prognosis ; Machine Learning
Czasopismo naukowe
Szczegóły
Tytuł:
Expression of TRX1 optimizes the antitumor functions of human CAR T cells and confers resistance to a pro-oxidative tumor microenvironment.
Autorzy:
Balta E; Section of Molecular Immunology, Institute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Janzen N; Section of Molecular Immunology, Institute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Kirchgessner H; Section of Molecular Immunology, Institute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Toufaki V; Section of Molecular Immunology, Institute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Orlik C; Section of Molecular Immunology, Institute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Liang J; Section of Molecular Immunology, Institute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Lairikyengbam D; Section of Molecular Immunology, Institute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Abken H; Leibniz Institute for Immunotherapy, Division of Genetic Immunotherapy, University Regensburg, Regensburg, Germany.
Niesler B; Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.; Counter Core Facility, Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany.
Müller-Decker K; Core Facility Tumor Models, German Cancer Research Center, Heidelberg, Germany.
Ruppert T; Mass Spectrometry Core Facility, Center for Molecular Biology, Heidelberg University, Heidelberg, Germany.
Samstag Y; Section of Molecular Immunology, Institute of Immunology, Heidelberg University Hospital, Heidelberg, Germany.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 14; Vol. 13, pp. 1063313. Date of Electronic Publication: 2022 Dec 14 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunotherapy, Adoptive*/methods
Neoplasms*/immunology
Neoplasms*/therapy
Oxidative Stress*/genetics
Oxidative Stress*/immunology
T-Lymphocytes*/immunology
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Humans ; Antioxidants/metabolism ; Oxidation-Reduction ; Thioredoxins/genetics ; Thioredoxins/immunology
Czasopismo naukowe
Szczegóły
Tytuł:
Monocytes educated by cancer-associated fibroblasts secrete exosomal miR-181a to activate AKT signaling in breast cancer cells.
Autorzy:
Pakravan K; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box: 14115-154, Tehran, Iran.
Mossahebi-Mohammadi M; Department of Hematology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Ghazimoradi MH; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box: 14115-154, Tehran, Iran.
Cho WC; Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong, China.
Sadeghizadeh M; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box: 14115-154, Tehran, Iran. .
Babashah S; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box: 14115-154, Tehran, Iran. .
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Źródło:
Journal of translational medicine [J Transl Med] 2022 Dec 03; Vol. 20 (1), pp. 559. Date of Electronic Publication: 2022 Dec 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/immunology
Cancer-Associated Fibroblasts*/immunology
MicroRNAs*/genetics
MicroRNAs*/immunology
Monocytes*/immunology
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Animals ; Humans ; Mice ; Macrophages/immunology ; Mice, Nude ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/immunology ; Reactive Oxygen Species ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of m A methylation patterns and tumor microenvironment in endometrial cancer.
Autorzy:
Chen J; Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Luo X; Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Wang G; Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Zhang J; Department of Gynecological Oncology, The First Affiliated Hospital of Bengbu Medical College, Anhui, China. Electronic address: .
Zhang Y; Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai 200092, China. Electronic address: .
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Źródło:
Gene [Gene] 2023 Feb 05; Vol. 852, pp. 147052. Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Microenvironment*/genetics
Endometrial Neoplasms*/genetics
Endometrial Neoplasms*/therapy
Female ; Humans ; Methylation ; Epigenesis, Genetic ; Eukaryota
Czasopismo naukowe
Szczegóły
Tytuł:
In-situ cryo-immune engineering of tumor microenvironment with cold-responsive nanotechnology for cancer immunotherapy.
Autorzy:
Ou W; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Stewart S; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
White A; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Kwizera EA; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Xu J; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Fang Y; Department of Medical and Molecular Genetics and Melvin and Bren Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Shamul JG; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Xie C; Thoracic and Gastrointestinal Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Nurudeen S; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD, 21201, USA.
Tirada NP; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD, 21201, USA.
Lu X; Department of Medical and Molecular Genetics and Melvin and Bren Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Tkaczuk KHR; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD, 21201, USA.
He X; Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA. .; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD, 21201, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Jan 24; Vol. 14 (1), pp. 392. Date of Electronic Publication: 2023 Jan 24.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/immunology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Immunotherapy*/methods
Neoplasms*/immunology
Neoplasms*/pathology
Tumor Microenvironment*/drug effects
Tumor Microenvironment*/immunology
Cryotherapy*/methods
Animals ; Female ; Mice ; Cell Line, Tumor ; Nanotechnology/methods
Czasopismo naukowe
Szczegóły
Tytuł:
Single-cell transcriptome analysis reveals heterogeneity and convergence of the tumor microenvironment in colorectal cancer.
Autorzy:
Xie S; Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Cai Y; Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Chen D; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Xiang Y; Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Department of Gastroenterology, Huzhou Central Hospital, Huzhou, Zhejiang, China.
Cai W; Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Mao J; Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Ye J; Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2023 Jan 04; Vol. 13, pp. 1003419. Date of Electronic Publication: 2023 Jan 04 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Microenvironment*/genetics
Colorectal Neoplasms*/genetics
Humans ; Single-Cell Gene Expression Analysis ; Immunosuppression Therapy ; Immunosuppressive Agents ; Lipids
Czasopismo naukowe
Szczegóły
Tytuł:
TYRO3 blockade enhances anti-PD-1 therapy response by modulating expression of CCN1 in tumor microenvironment.
Autorzy:
Park M; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Kuen DS; Laboratory of Immune Regulation, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Park J; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Choi M; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Kim Y; Department of Chemistry, Sungkyunkwan University, Suwon, South Korea.
Roh EC; College of Pharmacy, Dankook University, Cheonan, Chungnam, South Korea.
Choi YJ; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Kim YG; College of Pharmacy, Dankook University, Cheonan, Chungnam, South Korea.
Chung Y; Laboratory of Immune Regulation, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Cho SY; Department of Drug Discovery, Korea Research Institute of Chemical Technology, Daejeon, South Korea.
Kang KW; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea .
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Źródło:
Journal for immunotherapy of cancer [J Immunother Cancer] 2023 Jan; Vol. 11 (1).
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Microenvironment*
Mice ; Animals ; c-Mer Tyrosine Kinase ; Cell Line, Tumor ; Disease Models, Animal
Czasopismo naukowe
Szczegóły
Tytuł:
Immunological and Clinico-Molecular Features of Tumor Border Configuration in Colorectal Cancer.
Autorzy:
Sonal S; From the Department of General & Gastrointestinal Surgery (Sonal, Dinaux, Leijssen, Boudreau, Berger), Massachusetts General Hospital & Harvard Medical School, Boston, MA.
Deshpande V; Department of Pathology (Deshpande, Neyaz, Taylor), Massachusetts General Hospital & Harvard Medical School, Boston, MA.
Ting DT; the Massachusetts General Hospital Cancer Center & Harvard Medical School, Boston, MA (Ting, Pankaj).
Neyaz A; Department of Pathology (Deshpande, Neyaz, Taylor), Massachusetts General Hospital & Harvard Medical School, Boston, MA.
Pankaj A; the Massachusetts General Hospital Cancer Center & Harvard Medical School, Boston, MA (Ting, Pankaj).
Taylor MS; Department of Pathology (Deshpande, Neyaz, Taylor), Massachusetts General Hospital & Harvard Medical School, Boston, MA.
Dinaux AM; From the Department of General & Gastrointestinal Surgery (Sonal, Dinaux, Leijssen, Boudreau, Berger), Massachusetts General Hospital & Harvard Medical School, Boston, MA.
Leijssen LG; From the Department of General & Gastrointestinal Surgery (Sonal, Dinaux, Leijssen, Boudreau, Berger), Massachusetts General Hospital & Harvard Medical School, Boston, MA.
Boudreau C; From the Department of General & Gastrointestinal Surgery (Sonal, Dinaux, Leijssen, Boudreau, Berger), Massachusetts General Hospital & Harvard Medical School, Boston, MA.
Berger DL; From the Department of General & Gastrointestinal Surgery (Sonal, Dinaux, Leijssen, Boudreau, Berger), Massachusetts General Hospital & Harvard Medical School, Boston, MA.
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Źródło:
Journal of the American College of Surgeons [J Am Coll Surg] 2023 Jan 01; Vol. 236 (1), pp. 126-134. Date of Electronic Publication: 2022 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/immunology
Colorectal Neoplasms*/pathology
DNA Mismatch Repair*
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Humans ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/immunology ; Forkhead Transcription Factors/metabolism ; Immunohistochemistry ; Mutation
Czasopismo naukowe
Szczegóły
Tytuł:
Breaking the niche: multidimensional nanotherapeutics for tumor microenvironment modulation.
Autorzy:
Swetha KL; Department of Pharmacy, Birla Institute of Technology & Science, Vidya Vihar, Pilani, Rajasthan, 333031, India.
Maravajjala KS; Department of Pharmacy, Birla Institute of Technology & Science, Vidya Vihar, Pilani, Rajasthan, 333031, India.
Li SD; Faculty of Pharmaceutical Sciences, The University of British Columbia, 2405 Westbrook Mall, Vancouver, BC, Canada.
Singh MS; Department of Biotechnology, Bennett University, Greater Noida, Uttar Pradesh, 201310, India. .; Center of Excellence for Nanosensors and Nanomedicine, Bennett University, Greater Noida, Uttar Pradesh, 201310, India. .
Roy A; Department of Pharmacy, Birla Institute of Technology & Science, Vidya Vihar, Pilani, Rajasthan, 333031, India. .
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Źródło:
Drug delivery and translational research [Drug Deliv Transl Res] 2023 Jan; Vol. 13 (1), pp. 105-134. Date of Electronic Publication: 2022 Jun 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Tumor Microenvironment*
Ecosystem*
Nanomedicine ; Drug Combinations
Czasopismo naukowe
Szczegóły
Tytuł:
Characterization of m6A methylation modifications and tumor microenvironment infiltration in thyroid cancer.
Autorzy:
Ji FH; Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yang Z; Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Sun C; AMITA Health Saint Joseph Hospital Chicago, 2900 N. Lake Shore Drive, Chicago, IL, 60657, USA.
Lowe S; College of Osteopathic Medicine, Kansas City University, 1750 Independence Ave, Kansas City, MO, 64106, USA.
Qiu XG; Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. .
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Źródło:
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2023 Jan; Vol. 25 (1), pp. 269-282. Date of Electronic Publication: 2022 Sep 26.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Microenvironment*/genetics
Thyroid Neoplasms*/genetics
Humans ; Methylation ; RNA ; Adenosine
Czasopismo naukowe
Szczegóły
Tytuł:
SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma.
Autorzy:
Han L; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Zhou J; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Li L; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Wu X; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Shi Y; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Cui W; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Zhang S; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Hu Q; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Wang J; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Bai H; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Liu H; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Guo C; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Cao H; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Chao M; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Hu Y; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Mou Y; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Jiao Y; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Feng D; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Wang L; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. .
Qu Y; Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, China. .
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Źródło:
Cell death & disease [Cell Death Dis] 2022 Dec 24; Vol. 13 (12), pp. 1071. Date of Electronic Publication: 2022 Dec 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amino Acid Transport System ASC*/genetics
Amino Acid Transport System ASC*/physiology
Ferroptosis*/genetics
Glioma*/genetics
Glioma*/immunology
Glioma*/pathology
Minor Histocompatibility Antigens*/genetics
Minor Histocompatibility Antigens*/physiology
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Brain Neoplasms*/genetics
Brain Neoplasms*/immunology
Brain Neoplasms*/pathology
Humans ; Apoptosis/genetics ; Glioblastoma/genetics ; Glioblastoma/immunology ; Glioblastoma/pathology
Czasopismo naukowe
Szczegóły
Tytuł:
Study of epirubicin sustained-release chemoablation in tumor suppression and tumor microenvironment remodeling.
Autorzy:
Meng L; Department of Radiology, Chinese People's Armed Police (PAP) Hospital of Beijing, Beijing, China.
Wang Z; Department of Radiology, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Hou Z; Department of Radiology, Chinese People's Armed Police (PAP) Hospital of Beijing, Beijing, China.
Wang H; National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Zhang X; Department of Radiology, Chinese People's Armed Police (PAP) Hospital of Beijing, Beijing, China.
Zhang X; Department of Radiology, Chinese People's Armed Police (PAP) Hospital of Beijing, Beijing, China.
He X; Department of Radiology, Chinese People's Armed Police (PAP) Hospital of Beijing, Beijing, China.
Zhang X; Department of Radiology, Chinese People's Armed Police (PAP) Hospital of Beijing, Beijing, China.
Qin B; Department of Oncology, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Li J; Department of Radiology, Characteristic Medical Center, Chinese People's Armed Police Force, Tianjin, China.
Zhang Z; Department of Radiology, Chinese People's Armed Police (PAP) Hospital of Beijing, Beijing, China.
Xue X; Department of Radiology, Chinese People's Armed Police (PAP) Hospital of Beijing, Beijing, China.
Wei Y; Department of Radiology, Chinese People's Armed Police (PAP) Hospital of Beijing, Beijing, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 20; Vol. 13, pp. 1064047. Date of Electronic Publication: 2022 Dec 20 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Immunotherapy*/methods
Tumor Microenvironment*
Animals ; Mice ; Epirubicin/therapeutic use ; Programmed Cell Death 1 Receptor/metabolism ; Delayed-Action Preparations/pharmacology ; Neoplasm Recurrence, Local ; Drug Carriers/pharmacology ; Hydrogels/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Interplay of four types of RNA modification writers revealed distinct tumor microenvironment and biological characteristics in pancreatic cancer.
Autorzy:
Gao W; Department of Hepatopancreatobiliary Surgery, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Chen D; Department of Hepatopancreatobiliary Surgery, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.; Department of General Surgery, Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Translational Research for Pancreatic Neoplasms, Research Institute of Pancreatic Diseases, Shanghai Jiaotong University School of Medicine, Shanghai, China.; State Key Laboratory of Oncogenes and Related Genes, Institute of Translational Medicine, Shanghai Jiaotong University, Shanghai, China.
Liu J; Department of Hepatopancreatobiliary Surgery, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.; Department of Nephrology, Institute of Nephrology, 2nd Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Zang L; Department of Hepatopancreatobiliary Surgery, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xiao T; Department of General Surgery, Shaoyang University Affiliated Second Hospital, Shaoyang University, Shaoyang, Hunan, China.
Zhang X; Department of General Surgery, Affiliated Renhe Hospital of China Three Gorges University, Yichang, Hubei, China.
Li Z; Department of General Surgery, Affiliated Renhe Hospital of China Three Gorges University, Yichang, Hubei, China.
Zhu H; Department of Hepatopancreatobiliary Surgery, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yu X; Department of Hepatopancreatobiliary Surgery, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 19; Vol. 13, pp. 1031184. Date of Electronic Publication: 2022 Dec 19 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tumor Microenvironment*/genetics
Pancreatic Neoplasms*/genetics
Humans ; Carcinogenesis ; Cluster Analysis
SCR Disease Name:
Pancreatic Carcinoma
Czasopismo naukowe
Szczegóły
Tytuł:
Characteristics of the immunogenicity and tumor immune microenvironment in HER2 -amplified lung adenocarcinoma.
Autorzy:
Wang Q; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Mao Z; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Li W; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wang S; Department of Pathology, Tangdu Hospital, The Second Affiliated Hospital of Air Force Military Medical University, Xi'an, China.
Wang L; Department of Thoracic Surgery, Tangdu Hospital, The Second Affiliated Hospital of Air Force Military Medical University, Xi'an, China.
Chen L; Department of Pathology, Shaanxi Provincial People's Hospital, Xi'an, China.
Yang Z; Department of Pathology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Fu X; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jiang P; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Bai Y; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xu L; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhang S; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Hou Y; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Jia X; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jiang L; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Liu M; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhang G; Department of Pathology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jiang Y; Department of Pathology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Guo H; Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.; Centre for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.; Key Laboratory of Environment and Genes Related to Diseases, Xi'an Jiaotong University, Ministry of Education of China, Xi'an, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 15; Vol. 13, pp. 1042072. Date of Electronic Publication: 2022 Dec 15 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma of Lung*/genetics
Adenocarcinoma of Lung*/immunology
Adenocarcinoma of Lung*/pathology
Lung Neoplasms*/genetics
Lung Neoplasms*/immunology
Lung Neoplasms*/pathology
Stomach Neoplasms*
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Receptor, ErbB-2*/genetics
Receptor, ErbB-2*/immunology
Humans ; B7-H1 Antigen/metabolism ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/immunology ; DNA Copy Number Variations
Czasopismo naukowe
Szczegóły
Tytuł:
Construction of novel hypoxia-related gene model for prognosis and tumor microenvironment in endometrial carcinoma.
Autorzy:
Chen J; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Wang G; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Zhang D; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Luo X; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Zhang D; Department of Gynecological Oncology, Changchun Center Hospital, Changchun, Jilin, China.
Zhang Y; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
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Źródło:
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Dec 15; Vol. 13, pp. 1075431. Date of Electronic Publication: 2022 Dec 15 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tumor Microenvironment*/genetics
Endometrial Neoplasms*/genetics
Humans ; Female ; Hypoxia/genetics ; Fetal Hypoxia ; Prognosis
Czasopismo naukowe
Szczegóły
Tytuł:
Integration analysis identifies MYBL1 as a novel immunotherapy biomarker affecting the immune microenvironment in clear cell renal cell carcinoma: Evidence based on machine learning and experiments.
Autorzy:
Wang T; Urology Surgery Department, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Jian W; Urology Surgery Department, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Xue W; Urology Surgery Department, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Meng Y; Urology Surgery Department, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Xia Z; Urology Surgery Department, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Li Q; The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.
Xu S; The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.
Dong Y; The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.
Mao A; The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.
Zhang C; Urology Surgery Department, The First Affiliated Hospital of Harbin Medical University, Harbin, China.; The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 14; Vol. 13, pp. 1080403. Date of Electronic Publication: 2022 Dec 14 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/genetics
Carcinoma, Renal Cell*/immunology
Carcinoma, Renal Cell*/therapy
Kidney Neoplasms*/genetics
Kidney Neoplasms*/immunology
Kidney Neoplasms*/therapy
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Humans ; Algorithms ; Proto-Oncogene Proteins ; Trans-Activators ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/immunology
Czasopismo naukowe
Szczegóły
Tytuł:
Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence.
Autorzy:
Dai T; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Rosario SR; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Katsuta E; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Sawant Dessai A; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Paterson EJ; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Novickis AT; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Cortes Gomez E; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Zhu B; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
Liu S; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Wang H; Department of Molecular and Cellular Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Abrams SI; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Seshadri M; Department of Oral Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Bshara W; Department of Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Dasgupta S; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2022 Dec 06; Vol. 41 (10), pp. 111756.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Plasticity*
Tumor Microenvironment*
Animals ; Mice ; Metabolomics
Czasopismo naukowe
Szczegóły
Tytuł:
SnSe Nanosheets Mimic Lactate Dehydrogenase to Reverse Tumor Acid Microenvironment Metabolism for Enhancement of Tumor Therapy.
Autorzy:
Wang H; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Wang B; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Jiang J; State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China.
Wu Y; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Song A; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Wang X; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Yao C; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Dai H; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Xu J; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Zhang Y; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Ma Q; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Xu F; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
Li R; State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China.
Wang C; Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 05; Vol. 27 (23). Date of Electronic Publication: 2022 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Microenvironment*
Neoplasms*/metabolism
Mice ; Animals ; L-Lactate Dehydrogenase/metabolism ; Lactic Acid/metabolism ; Acids
Czasopismo naukowe
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