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Tytuł :
miR-125b promotes the NF-κB-mediated inflammatory response in NAFLD via directly targeting TNFAIP3.
Autorzy :
Zhang Q; Department of geriatrics, the third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yu K; Medical General Laboratory, the third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Cao Y; Department of Cardiology Ward, The First Hospital of Shijiazhuang, Shijiazhuang, Hebei, China.
Luo Y; Department of geriatrics, the third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Liu Y; Department of geriatrics, the third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Zhao C; Department of Infectious diseases, the third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Apr 01; Vol. 270, pp. 119071. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs/*genetics
Non-alcoholic Fatty Liver Disease/*genetics
Tumor Necrosis Factor alpha-Induced Protein 3/*metabolism
Animals ; Female ; Hep G2 Cells ; Humans ; Inflammation/pathology ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis/pathology ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/metabolism ; Middle Aged ; Models, Animal ; NF-KappaB Inhibitor alpha/metabolism ; NF-kappa B/metabolism ; Non-alcoholic Fatty Liver Disease/metabolism ; Signal Transduction/physiology ; Tumor Necrosis Factor alpha-Induced Protein 3/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Second-generation TNFα turnover model for improved analysis of test compound interventions in LPS challenge studies.
Autorzy :
Larsson J; Fraunhofer-Chalmers Centre, Chalmers Science Park, 412 88 Gothenburg, Sweden.; Department of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, 412 96 Gothenburg, Sweden.. Electronic address: .
Hoppe E; Grünenthal GmbH, Aachen, Germany.
Gautrois M; Grünenthal GmbH, Aachen, Germany.
Cvijovic M; Department of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, 412 96 Gothenburg, Sweden.
Jirstrand M; Fraunhofer-Chalmers Centre, Chalmers Science Park, 412 88 Gothenburg, Sweden.
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Oct 01; Vol. 165, pp. 105937. Date of Electronic Publication: 2021 Jul 11.
Typ publikacji :
Journal Article
MeSH Terms :
Lipopolysaccharides*
Tumor Necrosis Factor-alpha*
Anti-Inflammatory Agents/pharmacology ; Humans
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Polygenetic risk scores do not add predictive power to clinical models for response to anti-TNFα therapy in inflammatory bowel disease.
Autorzy :
Karmi N; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Bangma A; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Spekhorst LM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
van Dullemen HM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Visschedijk MC; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Dijkstra G; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Weersma RK; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Voskuil MD; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Festen EAM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
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Źródło :
PloS one [PLoS One] 2021 Sep 17; Vol. 16 (9), pp. e0256860. Date of Electronic Publication: 2021 Sep 17 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adalimumab/*therapeutic use
Colitis, Ulcerative/*drug therapy
Crohn Disease/*drug therapy
Gastrointestinal Agents/*therapeutic use
Immunologic Factors/*therapeutic use
Infliximab/*therapeutic use
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Adult ; Colitis, Ulcerative/genetics ; Colitis, Ulcerative/immunology ; Colitis, Ulcerative/pathology ; Crohn Disease/genetics ; Crohn Disease/immunology ; Crohn Disease/pathology ; Female ; Gene Expression ; Humans ; Immunotherapy/methods ; Male ; Middle Aged ; Multifactorial Inheritance ; Remission Induction ; Retrospective Studies ; Treatment Outcome ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Association between tumor necrosis factor alpha and lymphotoxin alpha gene polymorphisms and migraine occurrence among Jordanians.
Autorzy :
Hamad N; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Alzoubi KH; Department of Clinical Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan. .
Swedan SF; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Khabour OF; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, 22110, Jordan.
El-Salem K; Department of Neurosciences, Jordan University of Science and Technology, Irbid, 22110, Jordan.
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Źródło :
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2021 Sep; Vol. 42 (9), pp. 3625-3630. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article
MeSH Terms :
Lymphotoxin-alpha*/genetics
Migraine Disorders*/epidemiology
Migraine Disorders*/genetics
Tumor Necrosis Factor-alpha*/genetics
Case-Control Studies ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Male ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Functional characterization of TNF-α in pufferfish (Takifugu obscurus) in immune response and apoptosis against Aeromonas hydrophila.
Autorzy :
Kong L; Institute of Modern Aquaculture Science and Engineering, School of Life Sciences, South China Normal University, Guangzhou, China.
Qian K; Institute of Modern Aquaculture Science and Engineering, School of Life Sciences, South China Normal University, Guangzhou, China.
Wu S; Institute of Modern Aquaculture Science and Engineering, School of Life Sciences, South China Normal University, Guangzhou, China.
Li B; Institute of Modern Aquaculture Science and Engineering, School of Life Sciences, South China Normal University, Guangzhou, China.
Guo Z; Institute of Modern Aquaculture Science and Engineering, School of Life Sciences, South China Normal University, Guangzhou, China.
Yin X; Institute of Modern Aquaculture Science and Engineering, School of Life Sciences, South China Normal University, Guangzhou, China.; Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Guangdong Ocean University, Zhanjiang, China.
Huang Y; Guangdong South China Sea Key Laboratory of Aquaculture for Aquatic Economic Animals, Guangdong Ocean University, Zhanjiang, China.
Ye J; Institute of Modern Aquaculture Science and Engineering, School of Life Sciences, South China Normal University, Guangzhou, China.
Tu X; Institute of Modern Aquaculture Science and Engineering, School of Life Sciences, South China Normal University, Guangzhou, China.
Fu S; Institute of Modern Aquaculture Science and Engineering, School of Life Sciences, South China Normal University, Guangzhou, China.
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Źródło :
Journal of fish diseases [J Fish Dis] 2021 Sep; Vol. 44 (9), pp. 1343-1353. Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Fish Diseases/*immunology
Takifugu/*immunology
Tumor Necrosis Factor-alpha/*chemistry
Aeromonas hydrophila/physiology ; Amino Acid Sequence ; Animals ; Fish Diseases/microbiology ; Fish Proteins/analysis ; Gene Expression Regulation ; Gram-Negative Bacterial Infections/veterinary ; RNA, Messenger ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Background to new treatments for COVID-19, including its chronicity, through altering elements of the cytokine storm.
Autorzy :
Clark IA; Research School of Biology, Australian National University, Canberra, Australia.
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Źródło :
Reviews in medical virology [Rev Med Virol] 2021 Sep; Vol. 31 (5), pp. 1-13. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*drug therapy
Cytokine Release Syndrome/*drug therapy
Dexamethasone/*administration & dosage
Interleukin-17/*administration & dosage
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Animals ; COVID-19/genetics ; COVID-19/immunology ; Cytokine Release Syndrome/genetics ; Cytokine Release Syndrome/immunology ; Humans ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Association of an expanded inflammatory mediators response with clinical and laboratory data in the postoperative period of pulmonary resection: a prospective clinical study.
Autorzy :
Dias LIN; - Unicamp, Cirurgia Torácica - Campinas - SP - Brasil.
Leite VDP; - Unicamp, Cirurgia Torácica - Campinas - SP - Brasil.
Brandão JM; - Unicamp, Cirurgia Torácica - Campinas - SP - Brasil.
Roso AP; - Unicamp, Cirurgia Torácica - Campinas - SP - Brasil.
Miranda ECM; - Unicamp, Cirurgia Torácica - Campinas - SP - Brasil.
Antunes E; Unicamp, Farmacologia - Campinas - SP - Brasil.
Mussi RK; - Unicamp, Cirurgia Torácica - Campinas - SP - Brasil.
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Źródło :
Revista do Colegio Brasileiro de Cirurgioes [Rev Col Bras Cir] 2021 Nov 22; Vol. 48, pp. e20213008. Date of Electronic Publication: 2021 Nov 22 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Laboratories*
Tumor Necrosis Factor-alpha*
Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Postoperative Period ; Prospective Studies
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Tumour necrosis factor-alpha polymorphism -308 G/a and its protein in subjects with gingivitis.
Autorzy :
Becerra-Ruiz JS; Los Altos University Center, University of Guadalajara, Tepatitlán de Morelos, México.
Ramírez-De Los Santos S; Biosciences Research Institute, Los Altos University Center, University of Guadalajara, Tepatitlán de Morelos, México.
Alonso-Sánchez CC; Los Altos University Center, University of Guadalajara, Tepatitlán de Morelos, México.
Martínez-Esquivias F; Los Altos University Center, University of Guadalajara, Tepatitlán de Morelos, México.
Martínez-Pérez LA; Los Altos University Center, University of Guadalajara, Tepatitlán de Morelos, México.
Padilla-González AC; Department of Clinics, Los Altos University Center, University of Guadalajara, Tepatitlán de Morelos, México.
Rivera-Santana GA; Department of Clinics, Los Altos University Center, University of Guadalajara, Tepatitlán de Morelos, México.
Guerrero-Velázquez C; Institute for Research in Dentistry, University Center for Health Sciences, University of Guadalajara, Guadalajara, México.
López-Pulido EI; Biosciences Research Institute, Los Altos University Center, University of Guadalajara, Tepatitlán de Morelos, México.
Guzmán-Flores JM; Biosciences Research Institute, Los Altos University Center, University of Guadalajara, Tepatitlán de Morelos, México.
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Źródło :
Acta odontologica Scandinavica [Acta Odontol Scand] 2021 Nov; Vol. 79 (8), pp. 630-635. Date of Electronic Publication: 2021 May 22.
Typ publikacji :
Journal Article
MeSH Terms :
Gingivitis*/genetics
Tumor Necrosis Factor-alpha*/genetics
Cholesterol, HDL ; Genotype ; Humans ; Polymorphism, Genetic ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Overexpression of Transmembrane TNF Drives Development of Ectopic Lymphoid Structures in the Bone Marrow and B Cell Lineage Alterations in Experimental Spondyloarthritis.
Autorzy :
Kaaij MH; Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands; .; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Rip J; Department of Pulmonary Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
Jeucken KCM; Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Kan YY; Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
van Rooijen CCN; Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Saris J; Department of Gastroenterology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Tytgat Institute for Intestinal and Liver Research, Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Pots D; Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Frey S; Department of Internal Medicine 3, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany; and.
Grootjans J; Department of Gastroenterology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Tytgat Institute for Intestinal and Liver Research, Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Schett G; Department of Internal Medicine 3, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany; and.
van Duivenvoorde LM; Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Nolte MA; Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Hendriks RW; Department of Pulmonary Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
Corneth OBJ; Department of Pulmonary Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
van Hamburg JP; Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Baeten DLP; Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Tas SW; Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands; .; Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Nov 01; Vol. 207 (9), pp. 2337-2346. Date of Electronic Publication: 2021 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes/*immunology
Bone Marrow/*metabolism
Germinal Center/*immunology
Membrane Proteins/*metabolism
Osteitis/*immunology
Spondylitis, Ankylosing/*immunology
T-Lymphocytes/*immunology
Tertiary Lymphoid Structures/*immunology
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Bone Marrow/pathology ; Cell Differentiation ; Cell Lineage ; Cells, Cultured ; Disease Models, Animal ; Humans ; Immunoglobulin A/metabolism ; Membrane Proteins/genetics ; Mice ; Signal Transduction ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
An Anterior Cruciate Ligament Rupture Increases Levels of Urine N-terminal Cross-linked Telopeptide of Type I Collagen, Urine C-terminal Cross-linked Telopeptide of Type II Collagen, Serum Aggrecan ARGS Neoepitope, and Serum Tumor Necrosis Factor-α.
Autorzy :
Hagemans FJA; Department of Orthopaedics and Sports Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Orthopaedics, Center for Orthopaedic Research Alkmaar, Noordwest Ziekenhuisgroep, Alkmaar, the Netherlands.
Larsson S; Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden.
Reijman M; Department of Orthopaedics and Sports Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
Frobell RB; Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden.
Struglics A; Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden.
Meuffels DE; Department of Orthopaedics and Sports Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
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Źródło :
The American journal of sports medicine [Am J Sports Med] 2021 Nov; Vol. 49 (13), pp. 3534-3543. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anterior Cruciate Ligament Injuries*
Tumor Necrosis Factor-alpha*
Adult ; Aggrecans ; Anterior Cruciate Ligament ; Biomarkers ; Collagen Type I ; Collagen Type II ; Humans ; Synovial Fluid ; Young Adult
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Erythematous plaques with zosteriform distribution in a patient treated with TNF-α inhibitor adalimumab for psoriasis.
Autorzy :
Garcia-Melendo C; Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Cubiró X; Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Tubau C; Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Mozos A; Department of Pathology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Muñoz C; Department of Microbiology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Puig L; Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
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Źródło :
International journal of dermatology [Int J Dermatol] 2021 Nov; Vol. 60 (11), pp. 1366-1367. Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Psoriasis*/drug therapy
Tumor Necrosis Factor-alpha*
Adalimumab/adverse effects ; Etanercept ; Humans ; Infliximab ; Tumor Necrosis Factor Inhibitors
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
IFN-α and TNF-α serum levels and their association with disease severity in Egyptian children and adults with alopecia areata.
Autorzy :
Omar SI; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Hamza AM; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Eldabah N; Department of Clinical and Chemical Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Habiba DA; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
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Źródło :
International journal of dermatology [Int J Dermatol] 2021 Nov; Vol. 60 (11), pp. 1397-1404. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article
MeSH Terms :
Alopecia Areata*/diagnosis
Tumor Necrosis Factor-alpha*/blood
Interferon-alpha/*blood
Adult ; Case-Control Studies ; Child ; Egypt ; Humans ; Severity of Illness Index
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Structural insight into TNF-α inhibitors through combining pharmacophore-based virtual screening and molecular dynamic simulation.
Autorzy :
Qaiser H; Dr. Panjwani Center for Molecular Medicine and Drug Research, ICCBS, University of Karachi, Karachi, Pakistan.; Department of Mathematics, Aston University, Birmingham, United Kingdom.
Saeed M; Dr. Panjwani Center for Molecular Medicine and Drug Research, ICCBS, University of Karachi, Karachi, Pakistan.
Nerukh D; Department of Mathematics, Aston University, Birmingham, United Kingdom.
Ul-Haq Z; Dr. Panjwani Center for Molecular Medicine and Drug Research, ICCBS, University of Karachi, Karachi, Pakistan.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2021 Oct; Vol. 39 (16), pp. 5920-5939. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Dynamics Simulation*
Tumor Necrosis Factor-alpha*
Ligands ; Molecular Docking Simulation ; Small Molecule Libraries/pharmacology
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis.
Autorzy :
Fisher AL; Molecular, Cellular and Integrative Physiology Graduate Program, Graduate Programs in Bioscience, UCLA, Los Angeles, California, USA; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
Srole DN; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA; Molecular and Medical Pharmacology Graduate Program, Graduate Programs in Bioscience, UCLA, Los Angeles, California, USA.
Palaskas NJ; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
Meriwether D; Division of Cardiology, Department of Medicine, UCLA, Los Angeles, California, USA.
Reddy ST; Division of Cardiology, Department of Medicine, UCLA, Los Angeles, California, USA.
Ganz T; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
Nemeth E; Department of Medicine, Center for Iron Disorders, David Geffen School of Medicine, UCLA, Los Angeles, California, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Oct; Vol. 297 (4), pp. 101156. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Apoptosis/*drug effects
Cholesterol/*biosynthesis
Ferric Compounds/*pharmacology
Human Umbilical Vein Endothelial Cells/*metabolism
Iron/*metabolism
Quaternary Ammonium Compounds/*pharmacology
Tumor Necrosis Factor-alpha/*pharmacology
Humans ; Iron Overload/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Silicon, an important exposure marker in vivo in silicosis research.
Autorzy :
Wang H; School of Public Health, North China University of Science and Technology, Tangshan, 063210, China.; Hebei Key Laboratory of Organ Fibrosis, North China University of Science and Technology, Tangshan, 063210, China.
Cui J; School of Public Health, North China University of Science and Technology, Tangshan, 063210, China.
Hao X; School of Public Health, North China University of Science and Technology, Tangshan, 063210, China.; Hebei Key Laboratory of Organ Fibrosis, North China University of Science and Technology, Tangshan, 063210, China.
Guo L; School of Public Health, North China University of Science and Technology, Tangshan, 063210, China.; Hebei Key Laboratory of Organ Fibrosis, North China University of Science and Technology, Tangshan, 063210, China.
Zhao J; The Occupational Medicine Research Center, Peking University Third Hospital, Beijing, 100191, China.
Wang R; School of Public Health, North China University of Science and Technology, Tangshan, 063210, China.; Hebei Key Laboratory of Organ Fibrosis, North China University of Science and Technology, Tangshan, 063210, China.
Liu H; School of Public Health, North China University of Science and Technology, Tangshan, 063210, China. .; Hebei Key Laboratory of Organ Fibrosis, North China University of Science and Technology, Tangshan, 063210, China. .
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Źródło :
International archives of occupational and environmental health [Int Arch Occup Environ Health] 2021 Oct; Vol. 94 (7), pp. 1513-1522. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Inhalation Exposure*
Occupational Exposure*
Silicon/*blood
Silicosis/*blood
Transforming Growth Factor beta1/*blood
Tumor Necrosis Factor-alpha/*blood
Administration, Inhalation ; Adult ; Aged ; Animals ; Humans ; Iron ; Lung/drug effects ; Lung/immunology ; Lung/pathology ; Male ; Middle Aged ; Mining ; Pulmonary Surfactant-Associated Protein D/blood ; Rats, Wistar ; Silicon/urine ; Silicon Dioxide/administration & dosage ; Silicosis/diagnosis ; Silicosis/immunology ; Transforming Growth Factor beta1/immunology ; Tumor Necrosis Factor-alpha/immunology ; Uteroglobin/blood
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Chronic lymphocytic leukemia cells impair osteoblastogenesis and promote osteoclastogenesis: role of TNFα, IL-6 and IL-11 cytokines.
Autorzy :
Giannoni P; Dept. of Experimental Medicine, Biology Section, University of Genoa, Italy.
Marini C; CNR Institute of Bioimages and Molecular Physiology, Milan, Italy.
Cutrona G; Molecular Pathology Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Matis S; Molecular Pathology Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Capra MC; Molecular Pathology Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Puglisi F; Dept. of Experimental Medicine, Biology Section, University of Genoa, Italy.
Luzzi P; Dept. of Experimental Medicine, Biology Section, University of Genoa, Italy.
Pigozzi S; Pathological Anatomy Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Gaggero G; Pathologycal Anatomy Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Neri A; Dept. of Oncology and Hemato-Oncology,University of Milan, Italy.
Todoerti K; Dept. of Oncology and Hemato-Oncology,University of Milan, Italy.
Morabito F; Biotechnology Research Unit, Azienda Ospedaliera Aprigliano, Cosenza, Italy.
Ibatici A; Hematology Clinic, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Miglino M; Hematology Clinic, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Bergamaschi M; Hematology Clinic, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Bruno S; Dept. of Experimental Medicine, Anatomy Section, University of Genoa, Italy.
Sambuceti GM; Nuclear Medicine Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Ravetti JL; Pathological Anatomy Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
Ferrarini M; Dept. of Experimental Medicine, Anatomy Section, University of Genoa, Italy.
Fais F; Molecular Pathology Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
de Totero D; Molecular Pathology Unit, IRCCS-Ospedale Policlinico San Martino, Genoa, Italy.
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Źródło :
Haematologica [Haematologica] 2021 Oct 01; Vol. 106 (10), pp. 2598-2612. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Interleukin-11*/genetics
Interleukin-6*/genetics
Leukemia, Lymphocytic, Chronic, B-Cell*
Osteogenesis*
Tumor Necrosis Factor-alpha*/genetics
Cell Differentiation ; Cells, Cultured ; Cytokines ; Humans ; Osteoblasts ; Osteoclasts
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Pulmonary injury and oxidative stress in rats induced by inhaled sulfur mustard is ameliorated by anti-tumor necrosis factor-α antibody.
Autorzy :
Malaviya R; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA.
Bellomo A; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA.
Abramova E; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA.
Croutch CR; MRIGlobal, Kansas City, MO 64110, USA.
Roseman J; MRIGlobal, Kansas City, MO 64110, USA.
Tuttle R; MRIGlobal, Kansas City, MO 64110, USA.
Peters E; MRIGlobal, Kansas City, MO 64110, USA.
Casillas RP; Latham BioPharm Group, Cambridge, MA 02142, USA.
Sunil VR; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA.
Laskin JD; Department of Environmental and Occupational Health and Justice, School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.
Laskin DL; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Oct 01; Vol. 428, pp. 115677. Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Acute Lung Injury/*chemically induced
Acute Lung Injury/*drug therapy
Antibodies, Monoclonal/*therapeutic use
Mustard Gas/*toxicity
Oxidative Stress/*drug effects
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Acute Lung Injury/metabolism ; Animals ; Antibodies, Monoclonal/pharmacology ; Chemical Warfare Agents/toxicity ; Inhalation Exposure/adverse effects ; Male ; Mustard Gas/administration & dosage ; Oxidative Stress/physiology ; Rats ; Rats, Wistar ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression.
Autorzy :
Das P; Division of Structural Biology & Bio-informatics, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Mukherjee A; Division of Structural Biology & Bio-informatics, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Adak S; Division of Structural Biology & Bio-informatics, CSIR-Indian Institute of Chemical Biology, Kolkata, India. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Oct; Vol. 297 (4), pp. 101198. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Extracellular Vesicles/*enzymology
Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)/*metabolism
Leishmania major/*enzymology
Macrophages/*metabolism
Protozoan Proteins/*metabolism
Tumor Necrosis Factor-alpha/*biosynthesis
Animals ; Extracellular Vesicles/immunology ; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)/immunology ; Leishmania major/immunology ; Macrophages/immunology ; Mice ; Mice, Inbred BALB C ; Protozoan Proteins/immunology ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Additional large-scale studies are needed to clarify the relationship between TNFα gene and migraine risk.
Autorzy :
Jiang Z; Department of Forensic Medicine, School of Medicine & Forensics, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, 710061, Shaanxi, China.; Department of Neurology, Xijing Hospital of Air Force Medical University, Xi'an, Shaanxi, China.
Zhao L; Department of Forensic Medicine, School of Medicine & Forensics, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, 710061, Shaanxi, China.
Li T; Department of Forensic Medicine, School of Medicine & Forensics, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, 710061, Shaanxi, China. .
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Źródło :
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2021 Oct; Vol. 42 (10), pp. 4333-4334. Date of Electronic Publication: 2021 Jun 29.
Typ publikacji :
Letter
MeSH Terms :
Migraine Disorders*/genetics
Tumor Necrosis Factor-alpha*/genetics
Genetic Predisposition to Disease ; Humans
Opinia redakcyjna
Szczegóły
Podgląd okładki
Tytuł :
Combined effects of cyclic stretch and TNF-α on the osteogenic differentiation in MC3T3-E1 cells.
Autorzy :
Yao W; Shanxi Medical University School and Hospital of Stomatology, Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Taiyuan 030001, China. Electronic address: .
Gong Y; Shanxi Medical University School and Hospital of Stomatology, Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Taiyuan 030001, China.
Zhao B; Shanxi Medical University School and Hospital of Stomatology, Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Taiyuan 030001, China.
Li R; Shanxi Medical University School and Hospital of Stomatology, Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Taiyuan 030001, China.
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Źródło :
Archives of oral biology [Arch Oral Biol] 2021 Oct; Vol. 130, pp. 105222. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :
Journal Article
MeSH Terms :
Osteogenesis*
Tumor Necrosis Factor-alpha*
Cell Differentiation ; NF-kappa B ; Osteoblasts
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 165215

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