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Wyszukujesz frazę ""Tumor Necrosis Factor-alpha"" wg kryterium: Temat


Starter badań:

Tytuł:
STAT3 regulates inflammatory cytokine production downstream of TNFR1 by inducing expression of TNFAIP3/A20.
Autorzy:
Antonia RJ; Department of Surgery, University of California, San Francisco, San Francisco, California, USA.; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
Karelehto E; Department of Surgery, University of California, San Francisco, San Francisco, California, USA.; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
Toriguchi K; Department of Surgery, University of California, San Francisco, San Francisco, California, USA.; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
Matli M; Department of Surgery, University of California, San Francisco, San Francisco, California, USA.; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
Warren RS; Department of Surgery, University of California, San Francisco, San Francisco, California, USA.; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
Pfeffer LM; Department of Pathology and Laboratory Medicine (College of Medicine), and the Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Donner DB; Department of Surgery, University of California, San Francisco, San Francisco, California, USA.; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
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Źródło:
Journal of cellular and molecular medicine [J Cell Mol Med] 2022 Aug; Vol. 26 (16), pp. 4591-4601. Date of Electronic Publication: 2022 Jul 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Tumor Necrosis Factor, Type I*/genetics
Tumor Necrosis Factor-alpha*/metabolism
Animals ; Gene Expression ; Inflammation ; Janus Kinase 2/metabolism ; Mice ; Mice, Knockout ; NF-kappa B/metabolism ; STAT3 Transcription Factor/metabolism ; Tumor Necrosis Factor alpha-Induced Protein 3/genetics ; Tumor Necrosis Factor alpha-Induced Protein 3/metabolism
Czasopismo naukowe
Tytuł:
YAP9/A20 complex suppresses proinflammatory responses and provides novel anti-inflammatory therapeutic potentials.
Autorzy:
Yang FM; State Key Laboratory of Respiratory Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Shen L; State Key Laboratory of Respiratory Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Fan DD; State Key Laboratory of Respiratory Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Bai Y; State Key Laboratory of Respiratory Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Li B; State Key Laboratory of Respiratory Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Lee J; State Key Laboratory of Respiratory Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Aug 15; Vol. 13, pp. 914381. Date of Electronic Publication: 2022 Aug 15 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Lipopolysaccharides*/metabolism
Inflammation/*metabolism
Tumor Necrosis Factor alpha-Induced Protein 3/*metabolism
YAP-Signaling Proteins/*metabolism
Animals ; Inflammation/drug therapy ; Mice ; Protein Isoforms/metabolism ; Signal Transduction ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Increased protein phosphatase 5 expression in inflammation-induced left ventricular dysfunction in rats.
Autorzy:
Manilall A; Integrated Molecular Physiology Research Initiative, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa.
Mokotedi L; Integrated Molecular Physiology Research Initiative, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa.
Gunter S; Integrated Molecular Physiology Research Initiative, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa.
Le Roux R; Integrated Molecular Physiology Research Initiative, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa.
Fourie S; Integrated Molecular Physiology Research Initiative, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa.
Flanagan CA; Integrated Molecular Physiology Research Initiative, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa.
Millen AME; Integrated Molecular Physiology Research Initiative, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa. .
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Źródło:
BMC cardiovascular disorders [BMC Cardiovasc Disord] 2022 Dec 09; Vol. 22 (1), pp. 539. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Necrosis Factor-alpha*/pharmacology
Tumor Necrosis Factor-alpha*/metabolism
Ventricular Dysfunction, Left*/genetics
Rats ; Animals ; Soluble Guanylyl Cyclase ; Rats, Sprague-Dawley ; Cyclic GMP/metabolism ; Inflammation ; Collagen ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Autorzy:
Li B; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Lu Y; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Wang R; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Xu T; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Lei X; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Jin H; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Gao X; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Xie Y; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Liu X; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Zeng J; Department of Physiology, Zunyi Medical University, Zunyi, 563000, Guizhou, China. .
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Źródło:
Neurochemical research [Neurochem Res] 2023 Feb; Vol. 48 (2), pp. 519-536. Date of Electronic Publication: 2022 Oct 30.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Necrosis Factor-alpha*/pharmacology
Tumor Necrosis Factor-alpha*/metabolism
MicroRNAs*/metabolism
Mice ; Animals ; Reactive Oxygen Species/metabolism ; Caspase 3/metabolism ; Caspase 8/metabolism ; Caspase 8/pharmacology ; Receptors, Tumor Necrosis Factor, Type I ; bcl-2-Associated X Protein/metabolism ; GAP-43 Protein/metabolism ; Cell Line ; Apoptosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Hippocampus/metabolism
Czasopismo naukowe
Tytuł:
Expression of interleukin-1β, interleukin-4, interferon-γ and tumour necrosis factor α in different tissue in a dinitrochlorobenzene-induced ear swelling test in mice.
Autorzy:
Li CL; Department of Dermatology, Shijingshan teaching hospital of Capital Medical University, Beijing Shijingshan Hospital, Beijing, China.
Liu N; Department of Dermatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
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Źródło:
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) [Skin Res Technol] 2023 Jan; Vol. 29 (1), pp. e13255.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Necrosis Factor-alpha*/metabolism
Tumor Necrosis Factor-alpha*/pharmacology
Dinitrochlorobenzene*/toxicity
Mice ; Animals ; Interferon-gamma/metabolism ; Interleukin-4 ; Interleukin-1beta ; Cytokines/metabolism
Czasopismo naukowe
Tytuł:
Sex differences in the associations between psychological symptoms and tumor necrosis factor-alpha levels among obese and nonobese children aged 6-13 in Taiwan.
Autorzy:
Chen YH; School of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan; Research Center of Health Equity, College of Public Health, Taipei Medical University, Taipei, Taiwan.
Chiou HY; School of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan.
Wang HY; School of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan.
Chung KH; Department of Psychiatry and Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address: .
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Źródło:
Journal of affective disorders [J Affect Disord] 2023 Jan 01; Vol. 320, pp. 241-246. Date of Electronic Publication: 2022 Sep 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Overweight*/psychology
Tumor Necrosis Factor-alpha*
Humans ; Child ; Adolescent ; Female ; Male ; Cross-Sectional Studies ; Sex Characteristics ; Taiwan/epidemiology ; Obesity/epidemiology ; Body Mass Index
Czasopismo naukowe
Tytuł:
Intricate role of sleep deprivation in modulating depression: focusing on BDNF, VEGF, serotonin, cortisol, and TNF-α.
Autorzy:
Vaseghi S; Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran. .
Mostafavijabbari A; East Los Angeles College, Monterey Park, CA, USA.
Alizadeh MS; Department of Cognitive Neuroscience, Institute for Cognitive Science Studies (ICSS), Tehran, Iran.; Department of Cellular and Molecular Sciences, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Ghaffarzadegan R; Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran.
Kholghi G; Department of Psychology, Faculty of Human Sciences, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran.
Zarrindast MR; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
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Źródło:
Metabolic brain disease [Metab Brain Dis] 2023 Jan; Vol. 38 (1), pp. 195-219. Date of Electronic Publication: 2022 Nov 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Sleep Deprivation*
Tumor Necrosis Factor-alpha*/metabolism
Humans ; Vascular Endothelial Growth Factor A ; Hydrocortisone ; Depression/etiology ; Brain-Derived Neurotrophic Factor/metabolism ; Serotonin
Czasopismo naukowe
Tytuł:
Tumor necrosis factor-α-primed mesenchymal stem cell-derived exosomes promote M2 macrophage polarization via Galectin-1 and modify intrauterine adhesion on a novel murine model.
Autorzy:
Li J; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, China.
Pan Y; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, China.; Jiangsu International Laboratory of Immunity and Metabolism, The Department of Pathogenic Biology and Immunology, Xuzhou Medical University, Xuzhou, China.
Yang J; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, China.
Wang J; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, China.
Jiang Q; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, China.
Dou H; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, China.
Hou Y; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 16; Vol. 13, pp. 945234. Date of Electronic Publication: 2022 Dec 16 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Galectin 1*/genetics
Galectin 1*/metabolism
Macrophages*/metabolism
Mesenchymal Stem Cells*/metabolism
Tissue Adhesions*/genetics
Tissue Adhesions*/metabolism
Tissue Adhesions*/pathology
Tumor Necrosis Factor-alpha*/genetics
Tumor Necrosis Factor-alpha*/metabolism
Uterine Diseases*/genetics
Uterine Diseases*/metabolism
Uterine Diseases*/pathology
Animals ; Female ; Humans ; Mice ; Disease Models, Animal ; Exosomes/genetics ; Exosomes/metabolism
Czasopismo naukowe
Tytuł:
Akkermansia muciniphila ameliorates depressive disorders in a murine alcohol-LPS (mALPS) model.
Autorzy:
Guo D; Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu road, Hongshan district, Wuhan, China. .
Park C; Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu road, Hongshan district, Wuhan, China. .
Li Y; Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-imaging, Center for Artificial Biology, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China.
Li B; Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu road, Hongshan district, Wuhan, China. .
Yang Q; Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu road, Hongshan district, Wuhan, China. .
Deng Y; Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu road, Hongshan district, Wuhan, China. .
Gao NL; Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-imaging, Center for Artificial Biology, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China.
Li R; Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu road, Hongshan district, Wuhan, China. .
Wang X; Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu road, Hongshan district, Wuhan, China. .
Yi L; Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu road, Hongshan district, Wuhan, China. .
Liu Z; Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu road, Hongshan district, Wuhan, China. .
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Źródło:
Food & function [Food Funct] 2022 Dec 13; Vol. 13 (24), pp. 12766-12776. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Depressive Disorder*/chemically induced
Depressive Disorder*/therapy
Tumor Necrosis Factor-alpha*/genetics
Tumor Necrosis Factor-alpha*/metabolism
Akkermansia*
Probiotics*/therapeutic use
Complementary Therapies*/methods
Ethanol*/adverse effects
Animals ; Mice ; Dysbiosis/drug therapy ; Inflammation/drug therapy ; Inflammation/metabolism ; Lipopolysaccharides ; Serotonin
SCR Organism:
Akkermansia muciniphila
Czasopismo naukowe
Tytuł:
Selective Role of TNFα and IL10 in Regulation of Barrier Properties of the Colon in DMH-Induced Tumor and Healthy Rats.
Autorzy:
Bekusova V; Department of General Physiology, Faculty of Biology, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
Zudova T; Department of General Physiology, Faculty of Biology, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
Fatyykhov I; Department of General Physiology, Faculty of Biology, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
Fedorova A; Department of General Physiology, Faculty of Biology, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
Amasheh S; Department of Veterinary Medicine, Institute of Veterinary Physiology, Freie Universität Berlin, 14163 Berlin, Germany.
Markov AG; Department of General Physiology, Faculty of Biology, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 09; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Colonic Neoplasms*/chemically induced
Colonic Neoplasms*/metabolism
Interleukin-10*/metabolism
Tumor Necrosis Factor-alpha*/metabolism
Animals ; Rats ; Colon/metabolism ; Cytokines/metabolism ; Tight Junction Proteins/metabolism ; Tight Junctions/metabolism
Czasopismo naukowe
Tytuł:
Bifunctional effect of the inflammatory cytokine tumor necrosis factor α on megakaryopoiesis and platelet production.
Autorzy:
Chu T; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Hu S; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
Qi J; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Li X; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Zhang X; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China.
Tang Y; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yang M; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xu Y; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China.
Ruan CG; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China.
Han Y; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China.
Wu DP; National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China.
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Źródło:
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2022 Dec; Vol. 20 (12), pp. 2998-3010. Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Thrombopoiesis*
Tumor Necrosis Factor-alpha*/pharmacology
Tumor Necrosis Factor-alpha*/metabolism
Mice ; Animals ; Humans ; Megakaryocytes/metabolism ; Cytokines/metabolism ; Blood Platelets/metabolism
Czasopismo naukowe
Tytuł:
N-desulfated and reacetylated modification of heparin modulates macrophage polarization.
Autorzy:
Zhu M; Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Wu X; School of Life Sciences and Heath Engineering, Jiangnan University, Wuxi 214122, China.
Sun J; Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Zhou Z; Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Kang M; School of Life Sciences and Heath Engineering, Jiangnan University, Wuxi 214122, China.
Hu Y; Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Teng L; Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Feb 28; Vol. 229, pp. 354-362. Date of Electronic Publication: 2022 Dec 22.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Necrosis Factor-alpha*/pharmacology
Heparin*/pharmacology
Mice ; Animals ; Macrophages ; RAW 264.7 Cells ; Interleukin-6 ; Lipopolysaccharides/pharmacology
Czasopismo naukowe
Tytuł:
Combining high throughput array synthesis and growth algorithm to discover TNF-α binders with new structures and properties.
Autorzy:
Lin W; B CUBE Center for Molecular Bioengineering, Technische Universität Dresden, Tatzberg 41, 01307, Dresden, Germany; Suzhou Institute of Systems Medicine, Suzhou, Jiangsu, China.
Gandhi S; B CUBE Center for Molecular Bioengineering, Technische Universität Dresden, Tatzberg 41, 01307, Dresden, Germany.
Bhattarai P; Department of Neurology and The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 650 W 168th St, New York, NY, 10032, USA.
Kasa K; B CUBE Center for Molecular Bioengineering, Technische Universität Dresden, Tatzberg 41, 01307, Dresden, Germany.
Kizil C; Department of Neurology and The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 650 W 168th St, New York, NY, 10032, USA. Electronic address: .
Zhang Y; B CUBE Center for Molecular Bioengineering, Technische Universität Dresden, Tatzberg 41, 01307, Dresden, Germany; Cluster of Excellence 'Physics of Life', Technische Universität Dresden, 01062, Dresden, Germany. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2023 Feb 15; Vol. 248, pp. 115078. Date of Electronic Publication: 2023 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Necrosis Factor-alpha*/metabolism
Drug Discovery*
High-Throughput Screening Assays ; Protein Binding ; Small Molecule Libraries/pharmacology ; Small Molecule Libraries/chemistry
Czasopismo naukowe
Tytuł:
Ly-6A-Induced Growth Inhibition and Cell Death in a Transformed CD4 T Cell Line: Role of Tumor Necrosis Factor-α.
Autorzy:
Patel AG; Department of Biology, Villanova University, Villanova, PA, 19085, USA.
Moxham S; Department of Biology, Villanova University, Villanova, PA, 19085, USA.
Bamezai AK; Department of Biology, Villanova University, Villanova, PA, 19085, USA. .
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Źródło:
Archivum immunologiae et therapiae experimentalis [Arch Immunol Ther Exp (Warsz)] 2023 Feb 01; Vol. 71 (1), pp. 4. Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
Tumor Necrosis Factor-alpha*/metabolism
Humans ; Growth Differentiation Factor 10/metabolism ; Lymphocyte Activation ; Cell Line ; Antigens/metabolism ; Apoptosis ; CD4-Positive T-Lymphocytes ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł:
Sex-differences in anxiety, neuroinflammatory markers, and enhanced fear learning following chronic heroin withdrawal.
Autorzy:
Parekh SV; Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, CB#3720, Chapel Hill, NC, 27599-3270, USA.
Adams LO; Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, CB#3720, Chapel Hill, NC, 27599-3270, USA.
Barkell GA; Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, CB#3720, Chapel Hill, NC, 27599-3270, USA.
Lysle DT; Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, CB#3720, Chapel Hill, NC, 27599-3270, USA. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2023 Feb; Vol. 240 (2), pp. 347-359. Date of Electronic Publication: 2023 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Heroin*
Tumor Necrosis Factor-alpha*
Female ; Male ; Rats ; Animals ; Sex Characteristics ; Rats, Sprague-Dawley ; Anxiety ; Narcotics/pharmacology ; Fear
Czasopismo naukowe
Tytuł:
Co-expression of activating and inhibitory receptors on peritoneal fluid NK cells in women with endometriosis.
Autorzy:
Saeki S; Department of Obstetrics and Gynecology, Hyogo Medical University, School of Medicine, Nishinomiya, Hyogo, Japan. Electronic address: .
Fukui A; Department of Obstetrics and Gynecology, Hyogo Medical University, School of Medicine, Nishinomiya, Hyogo, Japan. Electronic address: .
Mai C; Department of Obstetrics and Gynecology, Hyogo Medical University, School of Medicine, Nishinomiya, Hyogo, Japan. Electronic address: .
Takeyama R; Department of Obstetrics and Gynecology, Hyogo Medical University, School of Medicine, Nishinomiya, Hyogo, Japan. Electronic address: .
Yamaya A; Department of Obstetrics and Gynecology, Hyogo Medical University, School of Medicine, Nishinomiya, Hyogo, Japan; Reproductive Medicine and Immunology, Obstetrics and Gynecology, Clinical Science Department, Chicago Medical School, Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA. Electronic address: .
Shibahara H; Department of Obstetrics and Gynecology, Hyogo Medical University, School of Medicine, Nishinomiya, Hyogo, Japan. Electronic address: .
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Źródło:
Journal of reproductive immunology [J Reprod Immunol] 2023 Feb; Vol. 155, pp. 103765. Date of Electronic Publication: 2022 Nov 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tumor Necrosis Factor-alpha*/metabolism
Endometriosis*
Humans ; Female ; Ascitic Fluid/metabolism ; NK Cell Lectin-Like Receptor Subfamily K ; Killer Cells, Natural ; Cytokines/metabolism
Czasopismo naukowe
Tytuł:
Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis.
Autorzy:
Jiang X; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China.
Lu Z; College of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.
Zhang Q; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China.
Yu J; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China.
Han D; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China.
Liu J; College of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.
Li P; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China. Electronic address: .
Li F; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China; College of Pharmacy, Xinjiang Medical University, Urumqi 830011, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2023 Feb; Vol. 110, pp. 154640. Date of Electronic Publication: 2023 Jan 01.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Necrosis Factor-alpha*/pharmacology
Arthritis, Rheumatoid*/drug therapy
Rats ; Animals ; Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein ; AMP-Activated Protein Kinases ; Molecular Docking Simulation ; Coumarins/pharmacology ; Inflammation/drug therapy ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Fibroblasts ; Cells, Cultured ; Synovial Membrane
Czasopismo naukowe
Tytuł:
Dark chocolate (70% cocoa) attenuates the inflammatory marker TNF-α in patients on hemodialysis.
Autorzy:
Ribeiro M; Graduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil; Graduate Program in Biological Sciences - Physiology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro (RJ), Brazil.
Fanton S; Graduate Program in Cardiovascular Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil.
Paiva BR; Graduate Program in Cardiovascular Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil.
Baptista BG; Graduate Program in Medical Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil.
Alvarenga L; Graduate Program in Medical Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil.
Ribeiro-Alves M; HIV/AIDS Clinical Research Center, National Institute of Infectology (INI/Fiocruz), Rio de Janeiro, Brazil.
Cardozo LF; Graduate Program in Cardiovascular Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil.
Mafra D; Graduate Program in Nutrition Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil; Graduate Program in Biological Sciences - Physiology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro (RJ), Brazil; Graduate Program in Medical Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil. Electronic address: .
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Źródło:
Clinical nutrition ESPEN [Clin Nutr ESPEN] 2023 Feb; Vol. 53, pp. 189-195. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chocolate*
Renal Dialysis*
Renal Insufficiency, Chronic*
Tumor Necrosis Factor-alpha*/blood
Humans ; Male ; Cacao ; Inflammation ; Female ; Adult ; Middle Aged ; Aged
Czasopismo naukowe
Tytuł:
Murine neonatal dermal fibroblast acquires a lymphoid tissue organizer cell-like activity upon synergistic activation of TNF-α receptor and LTβ receptor.
Autorzy:
Jin L; Medical School of Chinese PLA, Beijing, China; Department & Institute of General Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing, China.
Gao W; Medical School of Chinese PLA, Beijing, China; Department & Institute of General Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing, China.
Chen P; Medical School of Chinese PLA, Beijing, China; Department & Institute of General Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing, China.
Zhao W; School of Medicine, Nankai University, Tianjin, China.
Zhao Y; Medical School of Chinese PLA, Beijing, China; Department & Institute of General Surgery, the Eighth Medical Center of Chinese PLA General Hospital, Beijing, China.
Li D; Medical School of Chinese PLA, Beijing, China; Department & Institute of General Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing, China.
Zhou J; Department & Institute of General Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yu B; School of Life Sciences, Hebei University, Baoding, Hebei Province, China.
Dong G; Department & Institute of General Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing, China. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2023 Feb; Vol. 1870 (2), pp. 119399. Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Tumor Necrosis Factor-alpha*/genetics
Lymphoid Tissue*/metabolism
Mice ; Animals ; Lymphocytes/metabolism ; Lymphotoxin-alpha/genetics ; Lymphotoxin-alpha/metabolism ; Fibroblasts/metabolism
Czasopismo naukowe
Tytuł:
Chondroitin sulfate is not digested at all in the mouse small intestine but may suppress interleukin 6 expression induced by tumor necrosis factor-α.
Autorzy:
Kudo K; Department of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, 036-8564, Japan.
Kobayashi T; Department of Glycotechnology, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan.
Kasai K; Department of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, 036-8564, Japan.
Nozaka H; Department of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, 036-8564, Japan.
Nakamura T; Department of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, 036-8564, Japan. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Jan 29; Vol. 642, pp. 185-191. Date of Electronic Publication: 2022 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Chondroitin Sulfates*/metabolism
Tumor Necrosis Factor-alpha*
Mice ; Humans ; Animals ; Interleukin-6 ; Proteoglycans/metabolism ; Chondroitin ; Disaccharides ; Chondroitin Sulfate Proteoglycans/metabolism
Czasopismo naukowe

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