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    Tytuł:
    Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core.
    Autorzy:
    Poumbourios P; Burnet Institute, Melbourne, Australia.; Department of Microbiology, Monash University, Clayton, Australia.
    Langer C; Burnet Institute, Melbourne, Australia.
    Boo I; Burnet Institute, Melbourne, Australia.
    Zakir T; Burnet Institute, Melbourne, Australia.
    Center RJ; Burnet Institute, Melbourne, Australia.; Department of Microbiology at The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia.
    Akerman A; Kirby Institute, University of New South Wales, Kensington, Australia.
    Milogiannakis V; Kirby Institute, University of New South Wales, Kensington, Australia.
    Aggarwal A; Kirby Institute, University of New South Wales, Kensington, Australia.
    Johnstone BA; Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
    Ha J; Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
    Coulibaly F; Infection Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.
    Turville SG; Kirby Institute, University of New South Wales, Kensington, Australia.
    Drummer HE; Burnet Institute, Melbourne, Australia.; Department of Microbiology, Monash University, Clayton, Australia.; Department of Microbiology at The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, Australia.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2023 May 18; Vol. 19 (5), pp. e1010981. Date of Electronic Publication: 2023 May 18 (Print Publication: 2023).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Severe Acute Respiratory Syndrome*
    COVID-19*
    Humans ; Spike Glycoprotein, Coronavirus ; Angiotensin-Converting Enzyme 2 ; Antibodies, Neutralizing
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants.
    Autorzy:
    Tea F; Brain Autoimmunity Group, Kids Neuroscience Centre, Kids Research at the Children's Hospital at Westmead, Sydney, New South Wales, Australia.
    Ospina Stella A; The Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia.
    Aggarwal A; The Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia.
    Ross Darley D; St Vincent's Hospital, Sydney, New South Wales, Australia.; School of Medicine, St Vincent's Clinical School, The University of New South Wales, Sydney, New South Wales, Australia.
    Pilli D; Brain Autoimmunity Group, Kids Neuroscience Centre, Kids Research at the Children's Hospital at Westmead, Sydney, New South Wales, Australia.
    Vitale D; Westmead Institute for Medical Research, Sydney, New South Wales, Australia.
    Merheb V; Brain Autoimmunity Group, Kids Neuroscience Centre, Kids Research at the Children's Hospital at Westmead, Sydney, New South Wales, Australia.
    Lee FXZ; Brain Autoimmunity Group, Kids Neuroscience Centre, Kids Research at the Children's Hospital at Westmead, Sydney, New South Wales, Australia.
    Cunningham P; St Vincent's Applied Medical Research, Sydney, New South Wales, Australia.
    Walker GJ; New South Wales Health Pathology, Sydney, Australia.
    Fichter C; The Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia.
    Brown DA; Westmead Institute for Medical Research, Sydney, New South Wales, Australia.; New South Wales Health Pathology, Sydney, Australia.
    Rawlinson WD; New South Wales Health Pathology, Sydney, Australia.; School of Medical Sciences, Biotechnology and Biomolecular Sciences and School of Women's and Children's Health, The University of New South Wales Sydney, New South Wales, Australia.; Serology and Virology Division (SAViD), NSW HP SEALS, Randwick, Australia.
    Isaacs SR; New South Wales Health Pathology, Sydney, Australia.
    Mathivanan V; The Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia.
    Hoffmann M; Infection Biology Unit, German Primate Center, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany.
    Pöhlman S; Infection Biology Unit, German Primate Center, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany.
    Mazigi O; School of Medicine, St Vincent's Clinical School, The University of New South Wales, Sydney, New South Wales, Australia.; Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
    Christ D; School of Medicine, St Vincent's Clinical School, The University of New South Wales, Sydney, New South Wales, Australia.; Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
    Dwyer DE; New South Wales Health Pathology, Sydney, Australia.; Centre for Infectious Diseases & Microbiology, Public Health, New South Wales Health Pathology, Institute of Clinical Pathology & Medical Research (ICPMR), Westmead, Sydney, New South Wales, Australia.; Marie Bashir Institute for Biosecurity, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
    Rockett RJ; Centre for Infectious Diseases & Microbiology, Public Health, New South Wales Health Pathology, Institute of Clinical Pathology & Medical Research (ICPMR), Westmead, Sydney, New South Wales, Australia.; Marie Bashir Institute for Biosecurity, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
    Sintchenko V; New South Wales Health Pathology, Sydney, Australia.; Centre for Infectious Diseases & Microbiology, Public Health, New South Wales Health Pathology, Institute of Clinical Pathology & Medical Research (ICPMR), Westmead, Sydney, New South Wales, Australia.; Marie Bashir Institute for Biosecurity, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
    Hoad VC; Australian Red Cross Lifeblood, Melbourne, Victoria, Australia.
    Irving DO; Australian Red Cross Lifeblood, Melbourne, Victoria, Australia.; Faculty of Health, University of Technology, Sydney, New South Wales, Australia.
    Dore GJ; The Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia.; St Vincent's Hospital, Sydney, New South Wales, Australia.
    Gosbell IB; Australian Red Cross Lifeblood, Melbourne, Victoria, Australia.; School of Medicine, Western Sydney University, Sydney, New South Wales, Australia.
    Kelleher AD; The Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia.
    Matthews GV; The Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia.; St Vincent's Hospital, Sydney, New South Wales, Australia.
    Brilot F; Brain Autoimmunity Group, Kids Neuroscience Centre, Kids Research at the Children's Hospital at Westmead, Sydney, New South Wales, Australia.; Marie Bashir Institute for Biosecurity, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
    Turville SG; The Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia.
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    Źródło:
    PLoS medicine [PLoS Med] 2021 Jul 06; Vol. 18 (7), pp. e1003656. Date of Electronic Publication: 2021 Jul 06 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Neutralizing/*immunology
    SARS-CoV-2/*pathogenicity
    Adult ; Antibodies, Viral/immunology ; Female ; Humans ; Male ; Middle Aged ; Nucleocapsid Proteins/immunology ; SARS-CoV-2/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    HIV infection is influenced by dynamin at 3 independent points in the viral life cycle.
    Autorzy:
    Aggarwal A; The Kirby Institute, University of New South Wales, New South Wales, Australia.
    Hitchen TL; The Kirby Institute, University of New South Wales, New South Wales, Australia.
    Ootes L; The Kirby Institute, University of New South Wales, New South Wales, Australia.
    McAllery S; The Kirby Institute, University of New South Wales, New South Wales, Australia.
    Wong A; The Kirby Institute, University of New South Wales, New South Wales, Australia.
    Nguyen K; The Kirby Institute, University of New South Wales, New South Wales, Australia.
    McCluskey A; Centre for Chemical Biology, Chemistry, School of Environmental and Life Sciences, The University of Newcastle, Callaghan, Australia.
    Robinson PJ; Children's Medical Research Institute, The University of Sydney, New South Wales, Australia.
    Turville SG; The Kirby Institute, University of New South Wales, New South Wales, Australia.
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    Źródło:
    Traffic (Copenhagen, Denmark) [Traffic] 2017 Jun; Vol. 18 (6), pp. 392-410. Date of Electronic Publication: 2017 Apr 11.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Dynamins/*metabolism
    Endocytosis/*physiology
    Endosomes/*metabolism
    HIV Infections/*virology
    HIV-1/*physiology
    Cell Membrane/metabolism ; Cells, Cultured ; Humans ; Virus Internalization
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    HIV-1 entry and trans-infection of astrocytes involves CD81 vesicles.
    Autorzy:
    Gray LR; Centre for Biomedical Research, Burnet Institute, Melbourne, Victoria, Australia ; Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia.
    Turville SG; The Kirby Institute, Darlinghurst, New South Wales, Australia.
    Hitchen TL; The Kirby Institute, Darlinghurst, New South Wales, Australia.
    Cheng WJ; Centre for Biomedical Research, Burnet Institute, Melbourne, Victoria, Australia.
    Ellett AM; Centre for Biomedical Research, Burnet Institute, Melbourne, Victoria, Australia.
    Salimi H; Centre for Biomedical Research, Burnet Institute, Melbourne, Victoria, Australia.
    Roche MJ; Centre for Biomedical Research, Burnet Institute, Melbourne, Victoria, Australia.
    Wesselingh SL; Centre for Biomedical Research, Burnet Institute, Melbourne, Victoria, Australia ; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
    Gorry PR; Centre for Biomedical Research, Burnet Institute, Melbourne, Victoria, Australia ; Department of Infectious Diseases, Monash University, Victoria, Australia ; Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria, Australia.
    Churchill MJ; Centre for Biomedical Research, Burnet Institute, Melbourne, Victoria, Australia ; Department of Microbiology, Monash University, Victoria, Australia ; Department of Medicine, Monash University, Victoria, Australia.
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    Źródło:
    PloS one [PLoS One] 2014 Feb 28; Vol. 9 (2), pp. e90620. Date of Electronic Publication: 2014 Feb 28 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Virus Internalization*
    Astrocytes/*metabolism
    HIV-1/*metabolism
    Tetraspanin 28/*metabolism
    Astrocytes/virology ; Cell Line ; Coculture Techniques ; HEK293 Cells ; HIV-1/physiology ; Host-Pathogen Interactions ; Humans ; Microscopy, Fluorescence ; Protein Binding ; RNA Interference ; T-Lymphocytes/virology ; Temperature ; Tetraspanin 28/genetics ; Time Factors ; Transport Vesicles/metabolism ; Virus Replication
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytes.
    Autorzy:
    Mercier SK; Centre for Virus Research, Westmead Millennium Institute, Westmead, New South Wales, Australia ; University of Sydney, Sydney, New South Wales, Australia.
    Donaghy H
    Botting RA
    Turville SG
    Harman AN
    Nasr N
    Ji H
    Kusebauch U
    Mendoza L
    Shteynberg D
    Sandgren K
    Simpson RJ
    Moritz RL
    Cunningham AL
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2013 Oct; Vol. 9 (10), pp. e1003700. Date of Electronic Publication: 2013 Oct 17.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Lymphocyte Activation*
    Dendritic Cells/*immunology
    Dendritic Cells/*virology
    HIV Infections/*immunology
    HIV-1/*immunology
    T-Lymphocytes/*immunology
    Cell Adhesion/immunology ; Cells, Cultured ; Dendritic Cells/pathology ; HIV Infections/pathology ; Humans ; Monocytes/immunology ; Monocytes/pathology ; T-Lymphocytes/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes.
    Autorzy:
    Gray LR; Centre for Virology, Burnet Institute, Melbourne, Victoria, Australia.
    Tachedjian G
    Ellett AM
    Roche MJ
    Cheng WJ
    Guillemin GJ
    Brew BJ
    Turville SG
    Wesselingh SL
    Gorry PR
    Churchill MJ
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2013 Apr 16; Vol. 8 (4), pp. e62196. Date of Electronic Publication: 2013 Apr 16 (Print Publication: 2013).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Anti-HIV Agents/*pharmacology
    Astrocytes/*virology
    HIV-1/*drug effects
    Stavudine/*pharmacology
    Zidovudine/*pharmacology
    Cell Line ; Humans ; Reverse Transcriptase Inhibitors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells.
    Autorzy:
    Aggarwal A; Laboratory of HIV Biology, Immunovirology and Pathogenesis Program, The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia.
    Iemma TL
    Shih I
    Newsome TP
    McAllery S
    Cunningham AL
    Turville SG
    Pokaż więcej
    Źródło:
    PLoS pathogens [PLoS Pathog] 2012; Vol. 8 (6), pp. e1002762. Date of Electronic Publication: 2012 Jun 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    HIV*
    Carrier Proteins/*metabolism
    Dendritic Cells/*virology
    Host-Parasite Interactions/*physiology
    Pseudopodia/*virology
    CD4-Positive T-Lymphocytes/virology ; Cell Line ; Formins ; Humans ; Microscopy, Electron, Transmission ; Pseudopodia/ultrastructure ; Virion/metabolism ; Virion/ultrastructure
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity.
    Autorzy:
    Turville SG; Center for Biomedical Research, HIV and AIDS Program, Population Council, New York, New York, United States of America.
    Aravantinou M
    Miller T
    Kenney J
    Teitelbaum A
    Hu L
    Chudolij A
    Zydowsky TM
    Piatak M Jr
    Bess JW Jr
    Lifson JD
    Blanchard J
    Gettie A
    Robbiani M
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2008 Sep 08; Vol. 3 (9), pp. e3162. Date of Electronic Publication: 2008 Sep 08.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Anti-Infective Agents/*administration & dosage
    Anti-Infective Agents/*pharmacology
    Carrageenan/*pharmacology
    Reverse Transcriptase Inhibitors/*administration & dosage
    Animals ; CD4 Antigens/metabolism ; CD8 Antigens/metabolism ; Carrageenan/administration & dosage ; Dendritic Cells/virology ; Drug Evaluation, Preclinical ; Drug Resistance, Viral ; HIV Infections/prevention & control ; HIV Infections/transmission ; Humans ; Macaca ; Monocytes/virology ; Reverse Transcriptase Inhibitors/pharmacology ; Simian Acquired Immunodeficiency Syndrome/prevention & control ; Simian Acquired Immunodeficiency Syndrome/transmission ; Simian Immunodeficiency Virus/metabolism ; Viral Load
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics.
    Autorzy:
    Schweizer A; Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland.
    Rusert P
    Berlinger L
    Ruprecht CR
    Mann A
    Corthésy S
    Turville SG
    Aravantinou M
    Fischer M
    Robbiani M
    Amstutz P
    Trkola A
    Pokaż więcej
    Źródło:
    PLoS pathogens [PLoS Pathog] 2008 Jul 25; Vol. 4 (7), pp. e1000109. Date of Electronic Publication: 2008 Jul 25.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Ankyrin Repeat/*physiology
    Ankyrins/*pharmacology
    Anti-HIV Agents/*pharmacology
    CD4 Antigens/*immunology
    CD4-Positive T-Lymphocytes/*virology
    HIV/*pathogenicity
    Animals ; Ankyrins/immunology ; CD4-Positive T-Lymphocytes/immunology ; Cell Survival/drug effects ; Cross Reactions ; Dendritic Cells/immunology ; Dose-Response Relationship, Immunologic ; Enzyme-Linked Immunosorbent Assay ; Female ; HIV/immunology ; HIV Envelope Protein gp120/immunology ; Humans ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/immunology ; Leukocytes, Mononuclear/virology ; Lymphocyte Activation ; Macaca mulatta ; Male ; Mice ; Neutralization Tests ; Protein Engineering ; Virus Replication/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Resolution of de novo HIV production and trafficking in immature dendritic cells.
    Autorzy:
    Turville SG; Center for Biomedical Research, Population Council, 1230 York Avenue, New York, New York 10065, USA. stuart_turville@wmi.usyd.edu.au
    Aravantinou M
    Stössel H
    Romani N
    Robbiani M
    Pokaż więcej
    Źródło:
    Nature methods [Nat Methods] 2008 Jan; Vol. 5 (1), pp. 75-85. Date of Electronic Publication: 2007 Dec 02.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Dendritic Cells/*ultrastructure
    Dendritic Cells/*virology
    HIV/*physiology
    HIV/*ultrastructure
    Microscopy, Fluorescence/*methods
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    CD4 is expressed by epidermal Langerhans' cells predominantly as covalent dimers.
    Autorzy:
    Lynch GW; Centre for Virus Research, Westmead Millennium Institute, University of Sydney, Westmead Hospital, Sydney, Australia. Garry_ />Slaytor EK
    Elliott FD
    Saurajen A
    Turville SG
    Sloane AJ
    Cameron PU
    Cunningham AL
    Halliday GM
    Pokaż więcej
    Źródło:
    Experimental dermatology [Exp Dermatol] 2003 Oct; Vol. 12 (5), pp. 700-11.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Epidermal Cells*
    CD4 Antigens/*chemistry
    CD4 Antigens/*metabolism
    Langerhans Cells/*metabolism
    Antigens, CD1/metabolism ; Cell Fractionation ; Cells, Cultured ; Collagenases/pharmacology ; Dimerization ; Endopeptidases/pharmacology ; Humans ; Langerhans Cells/cytology ; Membrane Proteins/chemistry ; Membrane Proteins/metabolism ; Protein Structure, Quaternary ; Trypsin/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Diversity of receptors binding HIV on dendritic cell subsets.
    Autorzy:
    Turville SG; Center for Virus Research, Westmead Millennium Institute, Westmead Hospital and University of Sydney, Sydney, NSW 2145, Australia.
    Cameron PU
    Handley A
    Lin G
    Pöhlmann S
    Doms RW
    Cunningham AL
    Pokaż więcej
    Źródło:
    Nature immunology [Nat Immunol] 2002 Oct; Vol. 3 (10), pp. 975-83. Date of Electronic Publication: 2002 Sep 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Cell Adhesion Molecules*
    Lectins, C-Type*
    Mannose-Binding Lectins*
    Antigens, Surface/*metabolism
    CD4 Antigens/*metabolism
    HIV Envelope Protein gp120/*metabolism
    HIV-1/*metabolism
    Langerhans Cells/*metabolism
    Lectins/*metabolism
    Receptors, Cell Surface/*metabolism
    Receptors, HIV/*metabolism
    Antigens, CD ; CD4-Positive T-Lymphocytes/metabolism ; Cell Line, Transformed ; Cells, Cultured ; Dendritic Cells/cytology ; Dendritic Cells/metabolism ; Humans ; Langerhans Cells/cytology ; Mannose Receptor
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-15 z 15

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