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Tytuł:
Utilizing Proteomic Approaches to Uncover the Neuroprotective Effects of ACE Inhibitors: Implications for Alzheimer's Disease Treatment.
Autorzy:
Yang MH; Division of General & Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Ho TC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chang CC; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; School of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Su YS; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Yuan CH; Mass Spectrometry Laboratory, Department of Chemistry, National University of Singapore, Singapore 119077, Singapore.
Chuang KP; School of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; International Degree Program in Animal Vaccine Technology, International College, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.; Graduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.; Companion Animal Research Center, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
Tyan YC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Graduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Center for Tropical Medicine and Infectious Disease Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 08; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 08.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Humans ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Proteomics ; Antihypertensive Agents
Czasopismo naukowe
Tytuł:
Reversal of High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Metformin Combined with PGG, an Inducer of Glycine N-Methyltransferase.
Autorzy:
Yang MH; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.; Center of General Education, Shu-Zen Junior College of Medicine and Management, Kaohsiung 821, Taiwan.
Li WY; Laboratory of Important Infectious Diseases and Cancer, Graduate Institute of Biomedical and Pharmacological Science, School of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan.
Wu CF; Department of Veterinary Medicine, National Chiayi University, Chiayi City 600, Taiwan.
Lee YC; Laboratory of Important Infectious Diseases and Cancer, Graduate Institute of Biomedical and Pharmacological Science, School of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan.
Chen AY; School of Medicine, University of California, Davis, Sacramento, CA 95817, USA.
Tyan YC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Graduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.; School of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Research Center for Precision Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Chen YA; Laboratory of Important Infectious Diseases and Cancer, Graduate Institute of Biomedical and Pharmacological Science, School of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan.; National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County 350, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 03; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 03.
Typ publikacji:
Journal Article
MeSH Terms:
Metformin*/metabolism
Metformin*/pharmacology
Metformin*/therapeutic use
Non-alcoholic Fatty Liver Disease*/drug therapy
Non-alcoholic Fatty Liver Disease*/etiology
Non-alcoholic Fatty Liver Disease*/metabolism
Animals ; Diet, High-Fat/adverse effects ; Glycine N-Methyltransferase/genetics ; Glycine N-Methyltransferase/metabolism ; Liver/metabolism ; Mice ; Mice, Inbred C57BL ; Mitochondrial Proteins/metabolism ; Proteomics
Czasopismo naukowe
Tytuł:
Pigeon Circovirus over Three Decades of Research: Bibliometrics, Scoping Review, and Perspectives.
Autorzy:
Silva BBI; International Degree Program in Animal Vaccine Technology, International College, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
Urzo MLR; Microbiology Division, Institute of Biological Sciences, College of Arts and Sciences, University of the Philippines Los Baños, Los Baños 4031, Laguna, Philippines.; Graduate School, University of the Philippines Los Baños, Los Baños 4031, Laguna, Philippines.
Encabo JR; Microbiology Division, Institute of Biological Sciences, College of Arts and Sciences, University of the Philippines Los Baños, Los Baños 4031, Laguna, Philippines.
Simbulan AM; Microbiology Division, Institute of Biological Sciences, College of Arts and Sciences, University of the Philippines Los Baños, Los Baños 4031, Laguna, Philippines.
Lunaria AJD; Microbiology Division, Institute of Biological Sciences, College of Arts and Sciences, University of the Philippines Los Baños, Los Baños 4031, Laguna, Philippines.
Sedano SA; Veterinary Vaccines Laboratory, National Institute of Molecular Biology and Biotechnology, University of the Philippines Los Baños, Los Baños 4031, Laguna, Philippines.
Hsu KC; Language Center, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
Chen CC; Language Center, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.; You Guan Yi Biotechnology Company, Kaohsiung 807, Taiwan.
Tyan YC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; School of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung 804, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Graduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
Chuang KP; International Degree Program in Animal Vaccine Technology, International College, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.; School of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Graduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.; School of Dentistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Companion Animal Research Center, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
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Źródło:
Viruses [Viruses] 2022 Jul 08; Vol. 14 (7). Date of Electronic Publication: 2022 Jul 08.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Bird Diseases*
Circoviridae Infections*
Circovirus*
Animals ; Bibliometrics ; Capsid Proteins ; Columbidae
Czasopismo naukowe
Tytuł:
Hydrogels: Properties and Applications in Biomedicine.
Autorzy:
Ho TC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chang CC; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; School of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Neuroscience Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Electrical Engineering, I-Shou University, Kaohsiung 840, Taiwan.
Chan HP; Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.
Chung TW; Biomedical Engineering Research and Development Center, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Shu CW; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chuang KP; Graduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
Duh TH; Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Yang MH; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.; Center of General Education, Shu-Zen Junior College of Medicine and Management, Kaohsiung 821, Taiwan.
Tyan YC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; School of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Graduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 May 02; Vol. 27 (9). Date of Electronic Publication: 2022 May 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hydrogels*/chemistry
Hydrogels*/therapeutic use
Tissue Engineering*
Biocompatible Materials/chemistry ; Drug Delivery Systems ; Polymers/chemistry
Czasopismo naukowe
Tytuł:
The Evaluation of Left Ventricle Ischemic Extent in Patients with Significantly Suspicious Cardiovascular Disease by Tc-Sestamibi Dynamic SPECT/CT and Myocardial Perfusion Imaging: A Head-to-Head Comparison.
Autorzy:
Chan HP; Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.
Chang CC; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; School of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Electrical Engineering, I-Shou University, Kaohsiung 840, Taiwan.
Hu C; Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.
Wang WH; Department of Internal Medicine, Division of Cardiology, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.
Peng NJ; Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.; National Yang-Ming University, School of Medicine, Taipei 112, Taiwan.
Tyan YC; Research Center for Environmental Medicine, Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Graduate Institute of Animal Vaccine Technology, National Pingtung University of Science and Technology, Pingtung 900, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Yang MH; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.; Center of General Education, Shu-Zen Junior College of Medicine and Management, Kaohsiung 821, Taiwan.
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Źródło:
Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2021 Jun 16; Vol. 11 (6). Date of Electronic Publication: 2021 Jun 16.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Relationship between Semi-Quantitative Parameters of Thallium-201 Myocardial Perfusion Imaging and Coronary Artery Disease.
Autorzy:
Chang CC; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.; Department of Electrical Engineering, I-Shou University, Kaohsiung 84001, Taiwan.; School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Neuroscience Research Center, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Yang MH; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 81362, Taiwan.
Liu CT; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Chu HL; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Lin CY; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Yen WJ; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Chung CY; Department of Chemistry, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.
Ho SY; Department of Radiation Oncology, Chi Mei Medical Center, Tainan 71004, Taiwan.; Graduate Institute of Medical Science, Chang Jung Christian University, Tainan 71101, Taiwan.
Tyan YC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Graduate Institute of Animal Vaccine Technology, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan.
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Źródło:
Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2020 Sep 30; Vol. 10 (10). Date of Electronic Publication: 2020 Sep 30.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Does Routine Triple-Time-Point FDG PET/CT Imaging Improve the Detection of Liver Metastases?
Autorzy:
Yen YA; Department of Nuclear Medicine, Chi Mei Medical Center, No.901, Zhonghua Rd., Yongkang Dist., Tainan City 710, Taiwan.
Huang WS; Department of Nuclear Medicine, Taipei Veterans General Hospital, No.201, Section 2, Shipai Rd., Beitou Dist., Taipei City 112, Taiwan.
Chiu CH; Department of Nuclear Medicine, National Defense Medical Center/Tri-Service General Hospital, No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei City 114, Taiwan.
Tyan YC; Department of Medical Imaging and Radiological Sciences, Center for Infectious Disease and Cancer Research, Research Center for Environmental Medicine, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Wang JJ; Department of Medical Research, Chi Mei Medical Center, No.901, Zhonghua Rd., Yongkang Dist., Tainan City 710, Taiwan.
Wu LC; Department of Nuclear Medicine, Chi Mei Medical Center, No.901, Zhonghua Rd., Yongkang Dist., Tainan City 710, Taiwan.
Feng IJ; Department of Medical Research, Chi Mei Medical Center, No.901, Zhonghua Rd., Yongkang Dist., Tainan City 710, Taiwan.
Lee CH; Department of Nuclear Medicine, Chi Mei Medical Center, No.901, Zhonghua Rd., Yongkang Dist., Tainan City 710, Taiwan.
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Źródło:
Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2020 Aug 19; Vol. 10 (9). Date of Electronic Publication: 2020 Aug 19.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Utilizing Experimental Mouse Model to Identify Effectors of Hepatocellular Carcinoma Induced by HBx Antigen.
Autorzy:
Yang MH; National Mosquito-Borne Diseases Control Research Center, National Health Research Institutes, Miaoli 350, Taiwan.; Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.; Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.
Chen M; Department of Urology, Mackay Memorial Hospital, Taipei 104, Taiwan.; Department of Cosmetic Applications and Management, Mackay Junior College of Medicine, Nursing and Management, Taipei 112, Taiwan.; School of Medicine, Mackay Medical College, New Taipei City 252, Taiwan.
Mo HH; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Tsai WC; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chang YC; Department of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chang CC; Department of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Chen KC; Department of Pathology, Changhua Christian Hospital, Changhua 500, Taiwan.
Wu HY; Instrumentation Center, National Taiwan University, Taipei 106, Taiwan.
Yuan CH; Mass Spectrometry Laboratory, Department of Chemistry, National University of Singapore, Singapore 119077, Singapore.
Lee CH; Department of Biological Science, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Chen YA; Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.; Department of Medical Research and Education, Cheng Hsin General Hospital, Taipei 112, Taiwan.
Tyan YC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
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Źródło:
Cancers [Cancers (Basel)] 2020 Feb 10; Vol. 12 (2). Date of Electronic Publication: 2020 Feb 10.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Prognostic Significance of Metabolic Parameters and Textural Features on F-FDG PET/CT in Invasive Ductal Carcinoma of Breast.
Autorzy:
Chang CC; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Graduate Institute of Clinical Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.; Neuroscience Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chen CJ; Departments of Nuclear Medicine, Yuan's General Hospital, Kaohsiung, Taiwan.; Department of Health Business Administration, Meiho University, Pingtung, Taiwan.
Hsu WL; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chang SM; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Huang YF; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan.
Tyan YC; Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung, Taiwan. .; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2019 Jul 29; Vol. 9 (1), pp. 10946. Date of Electronic Publication: 2019 Jul 29.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms/*diagnostic imaging
Carcinoma, Ductal, Breast/*diagnostic imaging
Positron Emission Tomography Computed Tomography/*standards
Adult ; Aged ; Breast Neoplasms/pathology ; Carcinoma, Ductal, Breast/pathology ; Female ; Fluorodeoxyglucose F18 ; Glycolysis ; Humans ; Middle Aged ; Neoplasm Grading ; Neoplasm Invasiveness ; Predictive Value of Tests ; Radiopharmaceuticals ; Survival Analysis
Czasopismo naukowe
Tytuł:
Reduction of aluminum ion neurotoxicity through a small peptide application - NAP treatment of Alzheimer's disease.
Autorzy:
Yang MH; Institute of Biological Chemistry, Academia Sinica, Taipei, 115, Taiwan.; Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chen SC; Office of Research and Development, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Lin YF; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Lee YC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Huang MY; Department of Radiation Oncology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Department of Radiation Oncology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chen KC; Department of Pathology, Changhua Christian Hospital, Changhua 500, Taiwan.
Wu HY; Instrumentation Center, National Taiwan University, Taipei 106, Taiwan.
Lin PC; Department of Chemistry, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Gozes I; Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Adams Super Center for Brain Studies and Sagol School for Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
Tyan YC; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
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Źródło:
Journal of food and drug analysis [J Food Drug Anal] 2019 Apr; Vol. 27 (2), pp. 551-564. Date of Electronic Publication: 2019 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease/*drug therapy
Neuroprotective Agents/*pharmacology
Peptide Fragments/*pharmacology
Small Molecule Libraries/*pharmacology
Aluminum/toxicity ; Alzheimer Disease/chemically induced ; Alzheimer Disease/pathology ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Humans ; Ions/toxicity ; Neuroprotective Agents/chemistry ; Neurotoxins/toxicity ; Oxidation-Reduction ; Peptide Fragments/chemistry ; Small Molecule Libraries/chemistry ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma.
Autorzy:
Kant R; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Yen CH; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.; Research Center for Natural products and Drug Development (CHY), Kaohsiung Medical University, Kaohsiung, Taiwan.
Hung JH; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.; Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan.
Lu CK; National Research Institute of Chinese Medicine, Taipei, Taiwan.; Department of Life Sciences and Institute of Genome Sciences, College of Life Science, National Yang-Ming University, Taipei, Taiwan.
Tung CY; VYM Genome Research Center, National Yang-Ming University, Taipei, Taiwan.
Chang PC; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan.
Chen YH; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Tyan YC; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan. .; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. .; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung, Taiwan. .; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. .
Chen YA; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan. .; Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, College of Pharmacy, Taipei Medical University, Taipei, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2019 Feb 13; Vol. 9 (1), pp. 1968. Date of Electronic Publication: 2019 Feb 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular/*pathology
Glucosides/*metabolism
Glycine N-Methyltransferase/*metabolism
Liver Neoplasms/*pathology
Proto-Oncogene Proteins c-myc/*genetics
Adult ; Aged ; Aged, 80 and over ; Animals ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Down-Regulation/drug effects ; Female ; Glucosides/pharmacology ; Glycine N-Methyltransferase/genetics ; Hep G2 Cells ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Nude ; Middle Aged ; Promoter Regions, Genetic/genetics ; Proteasome Endopeptidase Complex/metabolism ; Transcriptional Activation/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
MicroRNA-224 down-regulates Glycine N-methyltransferase gene expression in Hepatocellular Carcinoma.
Autorzy:
Hung JH; Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan.; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Li CH; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Yeh CH; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Huang PC; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Fang CC; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Chen YF; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Lee KJ; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Chou CH; Institute of Bioinformatics and Systems Biology, National Chiao Tung University, HsinChu, Taiwan.
Cheng HY; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Huang HD; Institute of Bioinformatics and Systems Biology, National Chiao Tung University, HsinChu, Taiwan.; Department of Biological Science and Technology, National Chiao Tung University, HsinChu, Taiwan.
Chen M; Department of Urology, Mackay Memorial Hospital, Taipei, Taiwan.; School of Medicine, Mackay Medical College, New Taipei City, Taiwan.; Department of Cosmetic Applications and Management, Mackay Junior College of Medicine, Nursing and Management, Taipei, Taiwan.
Tsai TF; Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan.
Lin AM; Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan.; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.; Faculty of Pharmacy, Taipei, Taiwan, National Yang-Ming University, Taipei, Taiwan.
Yen CH; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.
Tsou AP; Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan.
Tyan YC; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan.
Chen YA; Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan. .; Gaduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Institute of Biomedical Sciences, National Sun Yat-sen University, Kaohsiung, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2018 Aug 16; Vol. 8 (1), pp. 12284. Date of Electronic Publication: 2018 Aug 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Enzymologic*
Gene Expression Regulation, Neoplastic*
Acyltransferases/*genetics
Carcinoma, Hepatocellular/*enzymology
Down-Regulation/*physiology
Liver Neoplasms/*enzymology
MicroRNAs/*physiology
3' Untranslated Regions ; Animals ; Carcinoma, Hepatocellular/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; HEK293 Cells ; Humans ; Liver Neoplasms/genetics ; Mice ; Mice, Transgenic ; MicroRNAs/genetics ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Multiple Bony Injuries on Bone Scan in a Case of Unsuspected Child Abuse.
Autorzy:
Chuang YW; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Hsu CC; Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan City, Taiwan.
Chang CC; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Lin CY; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Medical Imaging and Radiological Sciences, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chu HL; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Huang YF; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Medical Imaging and Radiological Sciences, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
Tyan YC; Department of Medical Imaging and Radiological Sciences, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan.; Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
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Źródło:
Case reports in medicine [Case Rep Med] 2017; Vol. 2017, pp. 3015941. Date of Electronic Publication: 2017 Jun 27.
Typ publikacji:
Case Reports
Raport
Tytuł:
Preparation and Characterization of Hyaluronic Acid-Polycaprolactone Copolymer Micelles for the Drug Delivery of Radioactive Iodine-131 Labeled Lipiodol.
Autorzy:
Chen SC; Office of Research and Development, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Yang MH; Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chung TW; Department of Biomedical Engineering, National Yang-Ming University, Taipei 112, Taiwan.
Jhuang TS; Invasive Cardiac Laboratory, Tan Tock Seng Hospital, Singapore 308433.
Yang JD; Department of Chemistry, Chung Yuan Christian University, Taoyuan 320, Taiwan.
Chen KC; Department of Pathology, Changhua Christian Hospital, Changhua 500, Taiwan.
Chen WJ; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Huang YF; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Jong SB; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Tsai WC; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Laboratory Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Lin PC; Department of Chemistry, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Tyan YC; Office of Research and Development, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
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Źródło:
BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 4051763. Date of Electronic Publication: 2017 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Delivery Systems*
Ethiodized Oil/*administration & dosage
Iodine Radioisotopes/*administration & dosage
Radiopharmaceuticals/*administration & dosage
Cell Line ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Contrast Media/administration & dosage ; Contrast Media/pharmacokinetics ; Contrast Media/toxicity ; Drug Carriers/chemistry ; Drug Stability ; Ethiodized Oil/pharmacokinetics ; Ethiodized Oil/toxicity ; Hep G2 Cells ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Hepatocytes/radiation effects ; Humans ; Hyaluronic Acid/analogs & derivatives ; Hydrophobic and Hydrophilic Interactions ; Iodine Radioisotopes/pharmacokinetics ; Iodine Radioisotopes/toxicity ; Micelles ; Particle Size ; Polyesters ; Radiopharmaceuticals/pharmacokinetics ; Radiopharmaceuticals/toxicity ; Solubility
Czasopismo naukowe

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