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Wyszukujesz frazę ""Ubiquitination"" wg kryterium: Temat


Tytuł :
Ubiquitination of PPAR-gamma by pVHL inhibits ACLY expression and lipid metabolism, is implicated in tumor progression.
Autorzy :
Noh KH; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Daejeon, Republic of Korea. Electronic address: .
Kang HM; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Daejeon, Republic of Korea.
Yoo W; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Daejeon, Republic of Korea.
Min Y; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Daejeon, Republic of Korea; Department of Biology, Chungnam National University, 34134 Daejeon, Republic of Korea.
Kim D; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Daejeon, Republic of Korea; Department of Functional Genomics, Korea University of Science and Technology (UST), 217 Gajeong-ro, Daejeon, Republic of Korea.
Kim M; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Daejeon, Republic of Korea; Department of Microbiology, Chungbuk National University, 28644, Chungbuk, Republic of Korea.
Wang S; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Daejeon, Republic of Korea.
Lim JH; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Daejeon, Republic of Korea. Electronic address: .
Jung CR; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Daejeon, Republic of Korea; Department of Functional Genomics, Korea University of Science and Technology (UST), 217 Gajeong-ro, Daejeon, Republic of Korea. Electronic address: .
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Źródło :
Metabolism: clinical and experimental [Metabolism] 2020 Sep; Vol. 110, pp. 154302. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination*
ATP Citrate (pro-S)-Lyase/*genetics
Lipid Metabolism/*drug effects
Neoplasms/*metabolism
PPAR gamma/*metabolism
Von Hippel-Lindau Tumor Suppressor Protein/*physiology
Animals ; Cell Line, Tumor ; Disease Progression ; Fatty Liver/metabolism ; Humans ; Mice ; Proteasome Endopeptidase Complex/physiology ; Von Hippel-Lindau Tumor Suppressor Protein/genetics
Czasopismo naukowe
Tytuł :
Ubiquitination in rheumatoid arthritis.
Autorzy :
Behl T; Chitkara College of Pharmacy, Chitkara University, Punjab, India. Electronic address: .
Chadha S; Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Sachdeva M; Fatima College of Health Sciences, Al Ain, United Arab Emirates.
Kumar A; Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Hafeez A; Glocal School of Pharmacy, Glocal University, Mirzapur Pole, Uttar Pradesh, India.
Mehta V; Department of Pharmacology, Government College of Pharmacy, Rohru, Ditt. Shimla, Himachal Pradesh, India.
Bungau S; Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
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Źródło :
Life sciences [Life Sci] 2020 Nov 15; Vol. 261, pp. 118459. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Ubiquitination*
Arthritis, Rheumatoid/*metabolism
Animals ; Arthritis, Rheumatoid/pathology ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Proteasome Endopeptidase Complex/metabolism ; Proteolysis ; Ubiquitin/metabolism
Czasopismo naukowe
Tytuł :
MDM2-Mediated Ubiquitination of Angiotensin-Converting Enzyme 2 Contributes to the Development of Pulmonary Arterial Hypertension.
Autorzy :
Shen H; Department of Cardiology, the Affiliated Hospital of Yangzhou University, Yangzhou University, China (H.S., K.G.).
Zhang J; Department of Cardiology, First Affiliated Hospital of Xi'an Jiaotong University, China (J.Z., C.W., Y.L., Z.-Y.Y.).; Division of Cardiology, Department of Medicine (J.Z., J.Y.-J.S.), University of California, San Diego, La Jolla.; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China (J.Z., C.W., Y.L., S.C., Q.Y.).
Wang C; Department of Cardiology, First Affiliated Hospital of Xi'an Jiaotong University, China (J.Z., C.W., Y.L., Z.-Y.Y.).; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China (J.Z., C.W., Y.L., S.C., Q.Y.).
Jain PP; Division of Pulmonary, Critical Care and Sleep Medicine (P.P.J., M.X., J.W., J.X.-J.Y.), University of California, San Diego, La Jolla.
Xiong M; Division of Pulmonary, Critical Care and Sleep Medicine (P.P.J., M.X., J.W., J.X.-J.Y.), University of California, San Diego, La Jolla.; Department of Critical Medicine, The Third Affiliated Hospital of Guangzhou Medical University, China (M.X.).
Shi X
Lei Y; Department of Cardiology, First Affiliated Hospital of Xi'an Jiaotong University, China (J.Z., C.W., Y.L., Z.-Y.Y.).; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China (J.Z., C.W., Y.L., S.C., Q.Y.).
Chen S; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China (J.Z., C.W., Y.L., S.C., Q.Y.).
Yin Q; Cardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, China (J.Z., C.W., Y.L., S.C., Q.Y.).
Thistlethwaite PA; Division of Cardiothoracic Surgery, Department of Surgery (P.A.T.), University of California, San Diego, La Jolla.
Wang J; Division of Pulmonary, Critical Care and Sleep Medicine (P.P.J., M.X., J.W., J.X.-J.Y.), University of California, San Diego, La Jolla.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, China (J.W.).
Gong K; Department of Cardiology, the Affiliated Hospital of Yangzhou University, Yangzhou University, China (H.S., K.G.).
Yuan ZY; Department of Cardiology, First Affiliated Hospital of Xi'an Jiaotong University, China (J.Z., C.W., Y.L., Z.-Y.Y.).
Yuan JX; Division of Pulmonary, Critical Care and Sleep Medicine (P.P.J., M.X., J.W., J.X.-J.Y.), University of California, San Diego, La Jolla.
Shyy JY; Division of Cardiology, Department of Medicine (J.Z., J.Y.-J.S.), University of California, San Diego, La Jolla.
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Źródło :
Circulation [Circulation] 2020 Sep 22; Vol. 142 (12), pp. 1190-1204. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination*
Peptidyl-Dipeptidase A/*metabolism
Proto-Oncogene Proteins c-mdm2/*metabolism
Pulmonary Arterial Hypertension/*pathology
AMP-Activated Protein Kinases/deficiency ; AMP-Activated Protein Kinases/genetics ; Animals ; Disease Susceptibility ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Lung/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Peptidyl-Dipeptidase A/genetics ; Polymorphism, Single Nucleotide ; Proto-Oncogene Proteins c-mdm2/antagonists & inhibitors ; Proto-Oncogene Proteins c-mdm2/genetics ; RNA Interference ; RNA, Small Interfering/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Envelope protein ubiquitination drives entry and pathogenesis of Zika virus.
Autorzy :
Giraldo MI; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.; Centro de Investigaciones Biomédicas, Universidad del Quindío, Armenia, Colombia.
Xia H; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Aguilera-Aguirre L; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.
Hage A; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.
van Tol S; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.
Shan C; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Xie X; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Sturdevant GL; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Robertson SJ; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
McNally KL; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Meade-White K; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Azar SR; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX, USA.; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.
Rossi SL; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
Maury W; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
Woodson M; Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA.
Ramage H; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.
Johnson JR; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California San Francisco, San Francisco, CA, USA.; Gladstone Institute for Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Krogan NJ; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California San Francisco, San Francisco, CA, USA.; Gladstone Institute for Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Morais MC; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.; Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA.
Best SM; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Shi PY; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA. .; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA. .; Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA. .; Sealy Institute for Vaccine Sciences, University of Texas Medical Branch, Galveston, TX, USA. .; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, USA. .
Rajsbaum R; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA. .; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA. .
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Źródło :
Nature [Nature] 2020 Sep; Vol. 585 (7825), pp. 414-419. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination*
Virus Internalization*
Viral Envelope Proteins/*chemistry
Viral Envelope Proteins/*metabolism
Zika Virus/*metabolism
Zika Virus/*pathogenicity
Animals ; Antibodies, Monoclonal/immunology ; Antibodies, Neutralizing/immunology ; Brain/metabolism ; Cell Line ; Culicidae/cytology ; Culicidae/virology ; Endosomes/metabolism ; Female ; Hepatitis A Virus Cellular Receptor 1/metabolism ; Humans ; Male ; Membrane Fusion ; Mice ; Organ Specificity ; Polyubiquitin/immunology ; Polyubiquitin/metabolism ; Tripartite Motif Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Viral Tropism ; Viremia/immunology ; Viremia/prevention & control ; Viremia/virology ; Virus Replication ; Zika Virus/chemistry ; Zika Virus/genetics ; Zika Virus Infection/prevention & control ; Zika Virus Infection/virology
Czasopismo naukowe
Tytuł :
The AlRabring7 E3-Ub-ligase mediates AlRab7 ubiquitination and improves ionic and oxidative stress tolerance in Saccharomyces cerevisiae.
Autorzy :
Agarwal P; Plant Omics Division, CSIR-Central Salt and Marine Chemicals Research Institute (CSIR-CSMCRI), Council of Scientific & Industrial Research (CSIR), Gijubhai Badheka Marg, Bhavnagar, 364 002, Gujarat, India. Electronic address: .
Patel K; Plant Omics Division, CSIR-Central Salt and Marine Chemicals Research Institute (CSIR-CSMCRI), Council of Scientific & Industrial Research (CSIR), Gijubhai Badheka Marg, Bhavnagar, 364 002, Gujarat, India.
More P; Plant Omics Division, CSIR-Central Salt and Marine Chemicals Research Institute (CSIR-CSMCRI), Council of Scientific & Industrial Research (CSIR), Gijubhai Badheka Marg, Bhavnagar, 364 002, Gujarat, India; Academy of Scientific and Innovative Research, (AcSIR), Ghaziabad, 201002, India.
Sapara KK; Plant Omics Division, CSIR-Central Salt and Marine Chemicals Research Institute (CSIR-CSMCRI), Council of Scientific & Industrial Research (CSIR), Gijubhai Badheka Marg, Bhavnagar, 364 002, Gujarat, India; Academy of Scientific and Innovative Research, (AcSIR), Ghaziabad, 201002, India.
Singh VK; Centre for Bioinformatics, School of Biotechnology, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India.
Agarwal PK; Plant Omics Division, CSIR-Central Salt and Marine Chemicals Research Institute (CSIR-CSMCRI), Council of Scientific & Industrial Research (CSIR), Gijubhai Badheka Marg, Bhavnagar, 364 002, Gujarat, India; Academy of Scientific and Innovative Research, (AcSIR), Ghaziabad, 201002, India.
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Źródło :
Plant physiology and biochemistry : PPB 2020 Jun; Vol. 151, pp. 689-704. Date of Electronic Publication: 2020 Apr 21.
Typ publikacji :
Journal Article
MeSH Terms :
Oxidative Stress*/genetics
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Ubiquitin-Protein Ligases*/metabolism
Ubiquitination*/genetics
Hydrogen Peroxide
Czasopismo naukowe
Tytuł :
Site-specific ubiquitination affects protein energetics and proteasomal degradation.
Autorzy :
Carroll EC; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Greene ER; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Martin A; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA. .; Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA. .; QB3 Institute for Quantitative Biosciences, University of California Berkeley, Berkeley, CA, USA. .
Marqusee S; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA. .; QB3 Institute for Quantitative Biosciences, University of California Berkeley, Berkeley, CA, USA. .; Department of Chemistry, University of California Berkeley, Berkeley, CA, USA. .; Chan Zuckerberg Biohub, San Francisco, CA, USA. .
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Źródło :
Nature chemical biology [Nat Chem Biol] 2020 Aug; Vol. 16 (8), pp. 866-875. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Proteasome Endopeptidase Complex/*metabolism
Ubiquitin/*chemistry
Ubiquitination/*genetics
Animals ; Bacterial Proteins/metabolism ; Humans ; Mice ; Polyubiquitin/metabolism ; Proteasome Endopeptidase Complex/chemistry ; Proteasome Endopeptidase Complex/genetics ; Protein Binding/physiology ; Proteolysis ; Ribonucleases/metabolism ; Ubiquitin/metabolism ; Ubiquitination/physiology
Czasopismo naukowe
Tytuł :
Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development.
Autorzy :
Green JL; Malaria Parasitology Laboratory, The Francis Crick Institute, London, United Kingdom.
Wu Y; Malaria Parasitology Laboratory, The Francis Crick Institute, London, United Kingdom.
Encheva V; Mass Spectrometry Proteomics, The Francis Crick Institute, London, United Kingdom.
Lasonder E; School of Biomedical Science, University of Plymouth, Plymouth, United Kingdom.
Prommaban A; Malaria Parasitology Laboratory, The Francis Crick Institute, London, United Kingdom.; Department of Biochemistry, Chiang Mai University, Chiang Mai, Thailand.
Kunzelmann S; Structural Biology Science Technology Platform, The Francis Crick Institute, London, United Kingdom.
Christodoulou E; Structural Biology Science Technology Platform, The Francis Crick Institute, London, United Kingdom.
Grainger M; Malaria Parasitology Laboratory, The Francis Crick Institute, London, United Kingdom.
Truongvan N; Rudolf Virchow Center for Experimental Biomedicine, Universität Würzburg, Würzburg, Germany.
Bothe S; Department of Chemistry and Pharmacy, University of Würzburg, Würzburg, Germany.
Sharma V; School of Biomedical Science, University of Plymouth, Plymouth, United Kingdom.
Song W; School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom.
Pinzuti I; School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom.
Uthaipibull C; National Center for Genetic Engineering and Biotechnology, Khlong Luang, Thailand.
Srichairatanakool S; Department of Biochemistry, Chiang Mai University, Chiang Mai, Thailand.
Birault V; Translation, The Francis Crick Institute, London, United Kingdom.
Langsley G; Laboratoire de Biologie Cellulaire Comparative des Apicomplexes, Institut Cochin, Université Paris Descartes, Paris, France.
Schindelin H; Rudolf Virchow Center for Experimental Biomedicine, Universität Würzburg, Würzburg, Germany.
Stieglitz B; School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom.
Snijders AP; Mass Spectrometry Proteomics, The Francis Crick Institute, London, United Kingdom.
Holder AA; Malaria Parasitology Laboratory, The Francis Crick Institute, London, United Kingdom.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Jun 22; Vol. 16 (6), pp. e1008640. Date of Electronic Publication: 2020 Jun 22 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination*
Merozoites/*metabolism
Plasmodium falciparum/*metabolism
Protozoan Proteins/*metabolism
Ubiquitin/*metabolism
Humans ; Plasmodium falciparum/genetics ; Protozoan Proteins/genetics ; Ubiquitin/genetics
Czasopismo naukowe
Tytuł :
Essential roles for deubiquitination in Leishmania life cycle progression.
Autorzy :
Damianou A; York Biomedical Research Institute and Department of Biology, University of York, United Kingdom.; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Burge RJ; York Biomedical Research Institute and Department of Biology, University of York, United Kingdom.
Catta-Preta CMC; York Biomedical Research Institute and Department of Biology, University of York, United Kingdom.
Geoghegan V; York Biomedical Research Institute and Department of Biology, University of York, United Kingdom.
Nievas YR; York Biomedical Research Institute and Department of Biology, University of York, United Kingdom.
Newling K; York Biomedical Research Institute and Department of Biology, University of York, United Kingdom.
Brown E; York Biomedical Research Institute and Department of Biology, University of York, United Kingdom.
Burchmore R; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Rodenko B; UbiQ Bio BV, Amsterdam Science Park, The Netherlands.
Mottram JC; York Biomedical Research Institute and Department of Biology, University of York, United Kingdom.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Jun 16; Vol. 16 (6), pp. e1008455. Date of Electronic Publication: 2020 Jun 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle*
Ubiquitination*
Deubiquitinating Enzymes/*metabolism
Leishmania mexicana/*enzymology
Protozoan Proteins/*metabolism
Animals ; Deubiquitinating Enzymes/genetics ; Female ; Gene Deletion ; Leishmania mexicana/genetics ; Mice ; Mice, Inbred BALB C ; Protozoan Proteins/genetics
Czasopismo naukowe
Tytuł :
Mass Spectrometry Analysis to Identify Ubiquitylation of EYFP-tagged CENP-A (EYFP-CENP-A).
Autorzy :
Niikura Y; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University; .
Fang L; Jiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University.
Kitagawa R; Greehey Children's Cancer Institute, Department of Molecular Medicine, UT Health Science Center San Antonio.
Li P; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University.
Xi Y; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University.
You J; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University.
Guo Y; Jiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University.
Kitagawa K; Greehey Children's Cancer Institute, Department of Molecular Medicine, UT Health Science Center San Antonio; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 Jun 10 (160). Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Mass Spectrometry*
Ubiquitination*
Bacterial Proteins/*metabolism
Centromere Protein A/*metabolism
Luminescent Proteins/*metabolism
Recombinant Fusion Proteins/*metabolism
Cell Survival ; Centromere ; HEK293 Cells ; Humans ; Mutant Proteins/metabolism ; Peptides/metabolism
Czasopismo naukowe
Tytuł :
H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes.
Autorzy :
Kwon M; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
Park K; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
Hyun K; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
Lee JH; Biology Department, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA.
Zhou L; Department of Chemistry, Princeton University, Frick Laboratory, Princeton, NJ 08544, USA.
Cho YW; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Ge K; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Skalnik DG; Biology Department, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA.
Muir TW; Department of Chemistry, Princeton University, Frick Laboratory, Princeton, NJ 08544, USA.
Kim J; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Jun 04; Vol. 48 (10), pp. 5442-5456.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination*
Histone-Lysine N-Methyltransferase/*metabolism
Histones/*metabolism
DNA-Binding Proteins/metabolism ; Histone-Lysine N-Methyltransferase/chemistry ; Humans ; Methylation ; Myeloid-Lymphoid Leukemia Protein/metabolism ; Neoplasm Proteins/metabolism ; Nucleosomes/enzymology ; Protein Domains ; Protein Subunits/metabolism
Czasopismo naukowe
Tytuł :
Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Autorzy :
Wang Y; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Zhan Q; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Wang X; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Li P; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Liu S; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Gao G; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Gao P; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. .; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 02; Vol. 11 (1), pp. 2751. Date of Electronic Publication: 2020 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination*
Bacteria/*metabolism
Ubiquitin/*metabolism
Ubiquitin-Conjugating Enzymes/*chemistry
Ubiquitin-Conjugating Enzymes/*metabolism
Catalysis ; Crystallography, X-Ray ; Humans ; Models, Molecular ; NF-kappa B/metabolism ; Protein Conformation ; Protein Interaction Domains and Motifs
Czasopismo naukowe
Tytuł :
[Research Progress of the Roles of Ubiquitination/Deubiquitination in Androgen Receptor Abnormalities and Prostate Cancer].
Autorzy :
Zhang WY; Department of Urology, Peking University People's Hospital,Beijing 100045,China.
Zhou JH; Department of Central Laboratory and Institute of Clinical Molecular Biology, Peking University People's Hospital,Beijing 100045,China.
Wang HR; Department of Urology, Peking University People's Hospital,Beijing 100045,China.
Mu Q; Department of Central Laboratory and Institute of Clinical Molecular Biology, Peking University People's Hospital,Beijing 100045,China.
Wang Q; Department of Urology, Peking University People's Hospital,Beijing 100045,China.
Xu KX; Department of Urology, Peking University People's Hospital,Beijing 100045,China.
Xu T; Department of Urology, Peking University People's Hospital,Beijing 100045,China.
Hu H; Department of Urology, Peking University People's Hospital,Beijing 100045,China.
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Źródło :
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae [Zhongguo Yi Xue Ke Xue Yuan Xue Bao] 2020 Apr 28; Vol. 42 (2), pp. 251-256.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Proteolysis*
Ubiquitination*
Prostatic Neoplasms/*pathology
Receptors, Androgen/*metabolism
Cell Line, Tumor ; Humans ; Male ; Prostatic Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Lysosomal integral membrane protein LGP85 (LIMP-2) is ubiquitinated at the N-terminal cytoplasmic domain.
Autorzy :
Fujimoto K; Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, 812-8582, Japan. Electronic address: .
Uchida S; Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, 812-8582, Japan.
Amen RNS; Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, 812-8582, Japan.
Ishii Y; Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, 812-8582, Japan.
Tanaka Y; Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, 812-8582, Japan.
Hirota Y; Division of Pharmaceutical Cell Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, 812-8582, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Apr 02; Vol. 524 (2), pp. 424-430. Date of Electronic Publication: 2020 Jan 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination*
CD36 Antigens/*metabolism
Lysosome-Associated Membrane Glycoproteins/*metabolism
Animals ; CD36 Antigens/chemistry ; COS Cells ; Chlorocebus aethiops ; Lysosome-Associated Membrane Glycoproteins/chemistry ; Lysosomes/metabolism ; Protein Domains ; Rats ; Ubiquitinated Proteins/chemistry ; Ubiquitinated Proteins/metabolism
Czasopismo naukowe
Tytuł :
Ufmylation Is Activated in Renal Cancer and Is Not Associated with von Hippel-Lindau Mutation.
Autorzy :
Wang S; Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Jia M; Department of Clinical Laboratory, Peking University People's Hospital, Beijing, People's Republic of China.
Su M; Department of Clinical Laboratory, Peking University People's Hospital, Beijing, People's Republic of China.
Hu X; Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Li J; Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Xu Y; Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Qiu W; Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2020 Apr; Vol. 39 (4), pp. 654-660. Date of Electronic Publication: 2020 Jan 30.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Renal Cell/*genetics
Kidney Neoplasms/*genetics
Ubiquitination/*genetics
Von Hippel-Lindau Tumor Suppressor Protein/*genetics
Autophagy/physiology ; Carcinoma, Renal Cell/pathology ; Cell Line, Tumor ; China ; Endoplasmic Reticulum Stress/physiology ; Humans ; Kidney Neoplasms/pathology ; Protein Kinase Inhibitors/pharmacology ; Proteins/metabolism ; Sunitinib/pharmacology ; Ubiquitination/physiology
Czasopismo naukowe
Tytuł :
Inhibition of XBP1s ubiquitination enhances its protein stability and improves glucose homeostasis.
Autorzy :
Sun H; Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China.
Wei G; Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China. Electronic address: .
Liu H; Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China.
Xiao D; Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200032, China.
Huang J; Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China.
Lu J; Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China.
Miao J; Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200032, China; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address: .
Liu J; Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China. Electronic address: .
Chen S; Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China. Electronic address: .
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Źródło :
Metabolism: clinical and experimental [Metabolism] 2020 Apr; Vol. 105, pp. 154046. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination/*genetics
X-Box Binding Protein 1/*genetics
Animals ; Diet, High-Fat ; Endoplasmic Reticulum Stress/drug effects ; Endoplasmic Reticulum Stress/genetics ; Forkhead Box Protein O1/biosynthesis ; Forkhead Box Protein O1/genetics ; Glucose/metabolism ; Glucose Tolerance Test ; HEK293 Cells ; Homeostasis ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mutation/genetics ; Obesity/genetics ; Proteasome Endopeptidase Complex ; Translocation, Genetic ; Ubiquitination/physiology
Czasopismo naukowe
Tytuł :
Five enzymes of the Arg/N-degron pathway form a targeting complex: The concept of superchanneling.
Autorzy :
Oh JH; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
Hyun JY; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
Chen SJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
Varshavsky A; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 May 19; Vol. 117 (20), pp. 10778-10788. Date of Electronic Publication: 2020 May 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Proteolysis*
Ubiquitination*
Ubiquitin-Protein Ligase Complexes/*metabolism
Amidohydrolases/metabolism ; Aminoacyltransferases/metabolism ; Proteasome Endopeptidase Complex/metabolism ; Saccharomyces cerevisiae ; Saccharomyces cerevisiae Proteins/metabolism ; Ubiquitin-Conjugating Enzymes/metabolism ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination.
Autorzy :
Kelliher JL; Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, United States.
West KL; Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, United States.
Gong Q; Hefei National Laboratory for Physical Science at the Microscale, School of Life Sciences, University of Science and Technology of China, 96 Jinzhai Road, 230027, Hefei, Anhui, China.
Leung JWC; Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, United States. .
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Źródło :
Nature communications [Nat Commun] 2020 May 18; Vol. 11 (1), pp. 2462. Date of Electronic Publication: 2020 May 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination*
Histones/*chemistry
Histones/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Amino Acid Sequence ; Evolution, Molecular ; HEK293 Cells ; Histones/genetics ; Humans ; Lysine/metabolism ; Protein Structure, Secondary ; Substrate Specificity ; Tumor Suppressor p53-Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł :
Modification of the host ubiquitome by bacterial enzymes.
Autorzy :
Berglund J; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, 1355 Museum Drive, Gainesville, 32611-0700, FL USA.
Gjondrekaj R; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, 1355 Museum Drive, Gainesville, 32611-0700, FL USA.
Verney E; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, 1355 Museum Drive, Gainesville, 32611-0700, FL USA.
Maupin-Furlow JA; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, 1355 Museum Drive, Gainesville, 32611-0700, FL USA.
Edelmann MJ; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, 1355 Museum Drive, Gainesville, 32611-0700, FL USA. Electronic address: .
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Źródło :
Microbiological research [Microbiol Res] 2020 May; Vol. 235, pp. 126429. Date of Electronic Publication: 2020 Feb 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Host-Pathogen Interactions*
Ubiquitination*
Bacteria/*enzymology
Animals ; Bacteria/pathogenicity ; Bacterial Infections ; Bacterial Proteins/metabolism ; Humans ; Protein Processing, Post-Translational ; Ubiquitin/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Virulence Factors
Czasopismo naukowe
Tytuł :
Ligand-induced monoubiquitination of BIK1 regulates plant immunity.
Autorzy :
Ma X; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA.; Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX, USA.
Claus LAN; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Ghent, Belgium.
Leslie ME; Department of Biochemistry, Interdisciplinary Plant Group, University of Missouri-Columbia, Columbia, MO, USA.; Elemental Enzymes, St Louis, MO, USA.
Tao K; Center for Genome Research and Biocomputing and Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR, USA.
Wu Z; Department of Structural Biology, Center for Proteomics and Metabolomics, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Developmental Neurobiology, Center for Proteomics and Metabolomics, St Jude Children's Research Hospital, Memphis, TN, USA.
Liu J; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA.; Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX, USA.
Yu X; Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX, USA.; Department of Plant Pathology and Microbiology, Texas A&M University, College Station, TX, USA.
Li B; Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX, USA.; Department of Plant Pathology and Microbiology, Texas A&M University, College Station, TX, USA.
Zhou J; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA.; Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX, USA.
Savatin DV; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Ghent, Belgium.
Peng J; Department of Structural Biology, Center for Proteomics and Metabolomics, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Developmental Neurobiology, Center for Proteomics and Metabolomics, St Jude Children's Research Hospital, Memphis, TN, USA.
Tyler BM; Center for Genome Research and Biocomputing and Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR, USA.
Heese A; Department of Biochemistry, Interdisciplinary Plant Group, University of Missouri-Columbia, Columbia, MO, USA.
Russinova E; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Ghent, Belgium.
He P; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA. .; Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX, USA. .
Shan L; Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX, USA. .; Department of Plant Pathology and Microbiology, Texas A&M University, College Station, TX, USA. .
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Źródło :
Nature [Nature] 2020 May; Vol. 581 (7807), pp. 199-203. Date of Electronic Publication: 2020 Apr 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Ubiquitination*
Arabidopsis/*immunology
Arabidopsis/*metabolism
Arabidopsis Proteins/*chemistry
Arabidopsis Proteins/*metabolism
Plant Immunity/*immunology
Protein-Serine-Threonine Kinases/*chemistry
Protein-Serine-Threonine Kinases/*metabolism
Receptors, Pattern Recognition/*immunology
Ubiquitin-Protein Ligases/*chemistry
Ubiquitin-Protein Ligases/*metabolism
Arabidopsis/enzymology ; Endocytosis ; Ligands ; Pathogen-Associated Molecular Pattern Molecules/immunology ; Phosphorylation ; Protein Kinases/metabolism
Czasopismo naukowe
Tytuł :
Ubiquitination of renal ENaC subunits in vivo.
Autorzy :
Frindt G; Department of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Bertog M; Institut für Zelluläre und Molekulare Physiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Korbmacher C; Institut für Zelluläre und Molekulare Physiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Palmer LG; Department of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 May 01; Vol. 318 (5), pp. F1113-F1121. Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ubiquitination*
Epithelial Sodium Channels/*metabolism
Kidney/*metabolism
Liddle Syndrome/*metabolism
Aldosterone/blood ; Animals ; Disease Models, Animal ; Epithelial Sodium Channels/genetics ; Female ; Liddle Syndrome/genetics ; Male ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Mutation ; Proteolysis ; Rats, Sprague-Dawley
Czasopismo naukowe

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