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Tytuł:
DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status.
Autorzy:
Jurmeister P; Institute of Pathology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117, Berlin, Germany. .; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), 69210, Heidelberg, Germany. .; Berlin Institute of Health, Anna-Louisa-Karsch-Straße 2, 10178, Berlin, Germany. .; Institute of Pathology, Ludwig Maximilians University Hospital Munich, Thalkirchner Str. 36, 80337, Munich, Germany. .
Weber K; German Breast Group, 63263, Neu-Isenburg, Germany.
Villegas S; Institute of Pathology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117, Berlin, Germany.
Karn T; Department of Gynecology and Obstetrics, Goethe University, Frankfurt, Germany.
Untch M; Department of Gynecology and Obstetrics, Breast Cancer Center, Helios-Klinikum Berlin, Buch, Germany.
Thieme A; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), 69210, Heidelberg, Germany.
Müller V; Department of Obstetrics and Gynecology, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Hamburg, Germany.
Taube E; Institute of Pathology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117, Berlin, Germany.
Fasching P; Brustzentrum, Universitätsklinikum Erlangen, Erlangen, Germany.
Schmitt WD; Institute of Pathology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117, Berlin, Germany.
Marmé F; Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany.
Stickeler E; Klinik für Gynäkologie und Geburtsmedizin, Universitätsklinikum Aachen, Aachen, Germany.
Sinn BV; Institute of Pathology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117, Berlin, Germany.
Jank P; Institute of Pathology, Philipps-University Marburg and University Hospital Marburg, Marburg, Germany.
Schem C; Mammazentrum Hamburg, Hamburg, Germany.
Klauschen F; Institute of Pathology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), 69210, Heidelberg, Germany.; Berlin Institute of Health, Anna-Louisa-Karsch-Straße 2, 10178, Berlin, Germany.
van Mackelenbergh M; University Hospital of Schleswig-Holstein, Campus Kiel, Germany.
Denkert C; Institute of Pathology, Philipps-University Marburg and University Hospital Marburg, Marburg, Germany.
Loibl S; German Breast Group, 63263, Neu-Isenburg, Germany.
Capper D; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), 69210, Heidelberg, Germany.; Berlin Institute of Health, Anna-Louisa-Karsch-Straße 2, 10178, Berlin, Germany.; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, 10117, Berlin, Germany.
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Źródło:
Clinical epigenetics [Clin Epigenetics] 2021 Oct 03; Vol. 13 (1), pp. 184. Date of Electronic Publication: 2021 Oct 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms/*genetics
Receptor, ErbB-2/*metabolism
Adult ; Breast Neoplasms/classification ; DNA Methylation/genetics ; DNA Methylation/physiology ; Female ; Gene Expression/genetics ; Humans ; Middle Aged ; Receptor, ErbB-2/analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
Autorzy:
Liu J; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China.
Prager-van der Smissen WJC; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Collée JM; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Biostatistics Unit, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus.; Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus.
Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Ahearn TU; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
Aittomäki K; Department of Clinical Genetics, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Ambrosone CB; Roswell Park Cancer Institute, Buffalo, NY, USA.
Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA.
Antonenkova NN; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.
Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Arnold N; Department of Gynaecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany.; Institute of Clinical Molecular Biology, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany.
Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute, Queen's University, Kingston, ON, Canada.
Augustinsson A; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Auvinen P; Cancer Center, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine, Oncology, University of Eastern Finland, Kuopio, Finland.; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.
Becher H; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Biometry and Clinical Epidemiology, Charité -Universitätsmedizin Berlin, Berlin, Germany.
Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Bermisheva M; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.
Bernstein L; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Bogdanova NV; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Bogdanova-Markov N; Institute of Human Genetics, University of Münster, Münster, Germany.
Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; iFIT-Cluster of Excellence, University of Tübingen, Tübingen, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Partner Site Tübingen, Tübingen, Germany.
Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Partner Site Tübingen, Tübingen, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
Briceno I; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.; Medical Faculty, Universidad de La Sabana, Bogota, Colombia.
Brucker SY; Department of Gynecology and Obstetrics, University of Tübingen, Tübingen, Germany.
Brüning T; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany.
Burwinkel B; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.
Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Cai H; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Campa D; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Biology, University of Pisa, Pisa, Italy.
Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Castelao JE; Oncology and Genetics Unit, Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain.
Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
Choi JY; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea.
Christiaens M; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Clarke CL; Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA.
Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Dwek M; School of Life Sciences, University of Westminster, London, UK.
Eccles DM; Faculty of Medicine, University of Southampton, Southampton, UK.
Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, USA.
Figueroa J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK.; Cancer Research UK Edinburgh Centre, The University of Edinburgh, Edinburgh, UK.
Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
Fritschi L; School of Public Health, Curtin University, Perth, Western Australia, Australia.
Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.
Gapstur SM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA.
García-Closas M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Gaudet MM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA.
Giles GG; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
Goldberg MS; Department of Medicine, McGill University, Montréal, QC, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montréal, QC, Canada.
Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Guénel P; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France.
Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden.
Harrington PA; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Hart SN; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Hartman M; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Surgery, National University Health System, Singapore, Singapore.
Hillemanns P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
Hou MF; Department of Surgery, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung, Taiwan.
Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Huo D; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.
Ito H; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Iwasaki M; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Jakimovska M; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', MASA, Skopje, Republic of North Macedonia.
Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland.
John EM; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.
Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kang D; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Keeman R; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.; Saint Petersburg State University, Saint-Petersburg, Russia.
Kim SW; Department of Surgery, Daerim Saint Mary's Hospital, Seoul, Korea.
Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Kristensen VN; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.
Kurian AW; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA, USA.
Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA.
Li J; Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore.
Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.
Lophatananon A; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Luben RN; Clinical Gerontology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland.
Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Margolin S; Department of Oncology, Södersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Mariapun S; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia.
Matsuo K; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Maurer T; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece.
Meindl A; Department of Gynecology and Obstetrics, University of Munich, Campus Großhadern, Munich, Germany.
Menon U; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials & Methodology, University College London, London, UK.
Milne RL; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
Muir K; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Laboratory Medicine Program, University Health Network, Toronto, ON, Canada.
Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.
Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Orr N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Ireland, UK.
Park SK; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Peterlongo P; Genome Diagnostics Program, IFOM - the FIRC Institute for Molecular Oncology, Milan, Italy.
Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', MASA, Skopje, Republic of North Macedonia.
Presneau N; School of Life Sciences, University of Westminster, London, UK.
Rack B; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany.
Rau-Murthy R; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Rennert G; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.
Rennert HS; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.
Rhenius V; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Ruebner M; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Saloustros E; Department of Oncology, University Hospital of Larissa, Larissa, Greece.
Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Schneeweiss A; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.; National Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany.
Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Shen CY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Public Health, China Medical University, Taichung, Taiwan.
Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC, Canada.
Sohn C; National Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany.
Southey MC; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia.
Spinelli JJ; Population Oncology, BC Cancer, Vancouver, BC, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Tamimi RM; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, UK.
Teo SH; Breast Cancer Research Programme, Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia.; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Torres D; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Truong T; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France.
Untch M; Department of Gynecology and Obstetrics, Helios Clinics Berlin-Buch, Berlin, Germany.
Vachon CM; Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA.
van Asperen CJ; Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Yamaji T; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Ziogas A; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA.
Ziv E; Department of Medicine, Institute for Human Genetics, UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
Torres-Mejía G; Center for Population Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.
Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands.
Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Martens JWM; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Hollestelle A; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands. .
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Corporate Authors:
NBCS Collaborators
ABCTB Investigators
Źródło:
Scientific reports [Sci Rep] 2020 Jun 16; Vol. 10 (1), pp. 9688. Date of Electronic Publication: 2020 Jun 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Breast Neoplasms/*genetics
Germ-Line Mutation/*genetics
Homeodomain Proteins/*genetics
Female ; Genetic Predisposition to Disease/genetics ; Genotyping Techniques ; Humans ; Middle Aged ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy.
Autorzy:
Di Cosimo S; Biomarker Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.
Appierto V; Biomarker Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.
Pizzamiglio S; Bioinformatics and Biostatistics Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.
Silvestri M; Biomarker Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.
Baselga J; Vall D'Hebron Institute of Oncology, 08035 Barcelona, Spain.
Piccart M; Department of Medical Oncology, Institut Jules Bordet and l'Université Libre de Bruxelles (U.L.B), 1000 Brussels, Belgium.
Huober J; Department of Obstetrics and Gynecology, University of Ulm, 89081 Ulm, Germany.
Izquierdo M; Novartis Pharmaceutical, 4002 Basel, Switzerland.
de la Pena L; SOLTI-Breast Cancer Research Group, 08035 Barcelona, Spain.
Hilbers FS; Breast International Group (BIG)-aisbl, 1000 Bruxelles, Belgium.
de Azambuja E; Department of Medical Oncology, Institut Jules Bordet and l'Université Libre de Bruxelles (U.L.B), 1000 Brussels, Belgium.
Untch M; Department of Gynecology and Obstetrics, Helios Klinikum Berlin-Buch, 13125 Berlin, Germany.
Pusztai L; Yale Cancer Center, Yale School of Medicine, New Haven, CT 06511, USA.
Pritchard K; Division of Medical Oncology, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, M4N 3M5 ON, Canada.
Nuciforo P; Vall D'Hebron Institute of Oncology, 08035 Barcelona, Spain.
Vincent-Salomon A; Groupe d'étude des facteurs pronostiques immunohistochimiques dans le cancer du sein, 75013 Unicancer, France.
Symmans F; Department of Pathology, The UT M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Apolone G; Scientific Directorate, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.
de Braud FG; Department of Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.
Iorio MV; Molecular Targeting Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.
Verderio P; Bioinformatics and Biostatistics Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.
Daidone MG; Biomarker Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Feb 18; Vol. 21 (4). Date of Electronic Publication: 2020 Feb 18.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Neoadjuvant Therapy*
Breast Neoplasms/*blood
Breast Neoplasms/*drug therapy
Circulating MicroRNA/*blood
Receptor, ErbB-2/*metabolism
Trastuzumab/*therapeutic use
Adult ; Aged ; Breast Neoplasms/genetics ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Humans ; Logistic Models ; Middle Aged ; Multivariate Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neutropenic complications in the PANTHER phase III study of adjuvant tailored dose-dense chemotherapy in early breast cancer.
Autorzy:
Papakonstantinou A; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; Breast Cancer, Endocrine Tumours and Sarcoma Section, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
Hedayati E; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; Breast Cancer, Endocrine Tumours and Sarcoma Section, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
Hellström M; CKC, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
Johansson H; CKC, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
Gnant M; Department of Surgery, Medical University of Vienna, Vienna, Austria.; Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria.
Steger G; Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria.; Department of Medical Oncology, Medical University, Vienna, Austria.; Gaston H. Glock Research Center, Medical University, Vienna, Austria.
Greil R; Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria.; IIIrd Medical Department, Cancer Cluster Salzburg, Salzburg Cancer Research Institute, Paracelsus Medical University Salzburg, Salzburg, Austria.
Untch M; Department of Obstetrics and Gynecology, Helios Klinikum Berlin-Buch, Berlin, Germany.
Moebus V; Department of Gynecology and Obstetrics, Klinikum Frankfurt Höchst, Academic Hospital of the Goethe University, Frankfurt, Germany.
Loibl S; German Breast Group, Neu-Isenburg, Germany.
Foukakis T; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; Breast Cancer, Endocrine Tumours and Sarcoma Section, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
Bergh J; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; Breast Cancer, Endocrine Tumours and Sarcoma Section, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
Matikas A; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; Breast Cancer, Endocrine Tumours and Sarcoma Section, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.
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Źródło:
Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2020 Jan; Vol. 59 (1), pp. 75-81. Date of Electronic Publication: 2019 Oct 04.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Antineoplastic Combined Chemotherapy Protocols/*adverse effects
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Breast Neoplasms/*blood
Breast Neoplasms/*drug therapy
Neutropenia/*chemically induced
Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Chemotherapy, Adjuvant ; Cyclophosphamide/administration & dosage ; Cyclophosphamide/adverse effects ; Docetaxel/administration & dosage ; Docetaxel/adverse effects ; Epirubicin/administration & dosage ; Epirubicin/adverse effects ; Female ; Fluorouracil/administration & dosage ; Fluorouracil/adverse effects ; Granulocyte Colony-Stimulating Factor/therapeutic use ; Humans ; Middle Aged ; Neutropenia/drug therapy ; Patient Safety ; Treatment Outcome ; Young Adult
SCR Protocol:
FEC protocol
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Two truncating variants in FANCC and breast cancer risk.
Autorzy:
Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany. .
Peterlongo P; Genome Diagnostics Program, IFOM - the FIRC Institute of Molecular Oncology, Milan, Italy.
Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland.
Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Ahearn T; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Anton-Culver H; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA.
Arndt V; Division of Clinical Epidemiology and Aging Research, C070, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute, Queen's University, Kingston, ON, Canada.
Augustinsson A; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Freeman LEB; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Beeghly-Fadiel A; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Bermisheva M; Institute of Biochemistry and Genetics of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.
Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.; Department of Oncology, Örebro University Hospital, Örebro, Sweden.
Bogdanova NV; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus.
Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Brauch H; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; iFIT Cluster of Excellence, University of Tübingen, Tübingen, Germany.
Brenner H; Division of Clinical Epidemiology and Aging Research, C070, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
Burwinkel B; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.
Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Chan TL; Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Centre, Happy Valley, Hong Kong.; Department of Pathology, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong.
Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
Choi JY; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea.
Christiansen H; Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.
Clarke CL; Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA.
Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Dwek M; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK.
Eccles DM; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Eriksson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Evans DG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, USA.
Figueroa J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh Medical School, Edinburgh, UK.; Cancer Research UK Edinburgh Centre, Edinburgh, UK.
Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
Fritschi L; School of Public Health, Curtin University, Perth, Western Australia, Australia.
Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Gago-Dominguez M; Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.
Gao C; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Gapstur SM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA.
García-Closas M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
García-Sáenz JA; Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
Gaudet MM; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA.
Giles GG; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Goldberg MS; Department of Medicine, McGill University, Montréal, QC, Canada.; Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montréal, QC, Canada.
Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
Guénel P; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France.
Haeberle L; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Södersjukhuset, Stockholm, Sweden.
Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hartman M; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Department of Surgery, National University Health System, Singapore, Singapore.
Hauke J; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Hein A; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Hillemanns P; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Hogervorst FBL; Family Cancer Clinic, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands.
Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
Howell T; Division of Cancer Sciences, University of Manchester, Manchester, UK.
Huo D; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.
Ito H; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Iwasaki M; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland.
Janni W; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany.
John EM; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.
Jung A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kang D; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Kapoor PM; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Medicine, University of Heidelberg, Heidelberg, Germany.
Khusnutdinova E; Institute of Biochemistry and Genetics of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russia.
Kim SW; Department of Surgery, Daerim Saint Mary's Hospital, Seoul, Korea.
Kitahara CM; Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Koutros S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Kristensen VN; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Kwong A; Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Centre, Happy Valley, Hong Kong.; Department of Surgery, The University of Hong Kong, Pok Fu Lam, Hong Kong.; Department of Surgery, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong.
Lambrechts D; VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium.
Marchand LL; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA.
Li J; Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore.
Lindström S; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA.; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Linet M; Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Lo WY; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany.
Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Lophatananon A; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Margolin S; Department of Oncology, Södersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Martinez E; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.; Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, USA.
Matsuo K; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece.
Meindl A; Department of Gynecology and Obstetrics, Ludwig Maximilian University of Munich, Munich, Germany.
Menon U; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials & Methodology, University College London, London, UK.
Milne RL; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
Mohd Taib NA; Breast Cancer Research Unit, UM Cancer Research Institute, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
Muir K; Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Mulligan AM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Laboratory Medicine Program, University Health Network, Toronto, ON, Canada.
Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Neven P; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Newman WG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.
Olshan AF; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Park SK; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.; Cancer Research Institute, Seoul National University, Seoul, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', Macedonian Academy of Sciences and Arts, Skopje, Republic of Macedonia.
Pohl-Rescigno E; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Presneau N; Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, UK.
Rack B; Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany.
Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.
Rashid MU; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan.
Rennert G; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.
Rennert HS; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel.
Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Ruebner M; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Saloustros E; Department of Oncology, University Hospital of Larissa, Larissa, Greece.
Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands.
Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Schneider MO; Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany.
Schoemaker MJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Shen CY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Public Health, China Medical University, Taichung, Taiwan.
Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC, Canada.
Slager S; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Smichkoska S; Ss. Cyril and Methodius University in Skopje, Medical Faculty, University Clinic of Radiotherapy and Oncology, Skopje, Republic of Macedonia.
Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia.
Spinelli JJ; Population Oncology, BC Cancer, Vancouver, BC, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Stone J; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; The Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Western Australia, Australia.
Surowy H; Molecular Epidemiology Group, C080, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.
Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.
Tamimi RM; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, UK.
Teo SH; Breast Cancer Research Unit, UM Cancer Research Institute, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia.
Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Toland AE; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.
Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Torres D; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Human Genetics, Pontificia Universidad Javeriana, Bogota, Colombia.
Torres-Mejía G; Center for Population Health Research, National Institute of Public Health, Mexico, Mexico.
Troester MA; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Truong T; Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France.
Tsugane S; Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Untch M; Department of Gynecology and Obstetrics, Helios Clinics Berlin-Buch, Berlin, Germany.
Vachon CM; Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA.
Ouweland AMWVD; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Veen EMV; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.; Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Vijai J; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Wendt C; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Yu JC; Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Ziogas A; Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA.
Ziv E; Department of Medicine, Institute for Human Genetics, UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
Schindler D; Institute of Human Genetics, Biocenter, University of Würzburg, Würzburg, Germany.
Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
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Corporate Authors:
ABCTB Investigators
NBCS Collaborators
Źródło:
Scientific reports [Sci Rep] 2019 Aug 29; Vol. 9 (1), pp. 12524. Date of Electronic Publication: 2019 Aug 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Sequence Deletion*
Breast Neoplasms/*genetics
Fanconi Anemia Complementation Group C Protein/*genetics
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Breast Neoplasms/metabolism ; Case-Control Studies ; Fanconi Anemia/genetics ; Fanconi Anemia Complementation Group C Protein/metabolism ; Female ; Genetic Predisposition to Disease ; Genetic Variation ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intrinsic Subtypes of Primary Breast Cancer--Gene Expression Analysis.
Autorzy:
Schmidt M; Department of Obstetrics and Gynecology, University Hospital, Mainz, Germany.
Thomssen C
Untch M
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Źródło:
Oncology research and treatment [Oncol Res Treat] 2016; Vol. 39 (3), pp. 102-10. Date of Electronic Publication: 2016 Feb 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
Breast Neoplasms/*classification
Breast Neoplasms/*metabolism
Gene Expression Profiling/*methods
Neoplasm Proteins/*metabolism
Breast Neoplasms/pathology ; Female ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Treatment Modification in Young Breast Cancer Patients.
Autorzy:
Scharl A; Frauenklinik, Klinikum St. Marien Amberg, Amberg, Germany.
Salterberg A
Untch M
Liedtke C
Stickeler E
Papathemelis T
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Źródło:
Oncology research and treatment [Oncol Res Treat] 2016; Vol. 39 (3), pp. 122-8. Date of Electronic Publication: 2016 Feb 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents, Hormonal/*administration & dosage
Breast Neoplasms/*therapy
Tamoxifen/*administration & dosage
Adolescent ; Adult ; Breast Neoplasms/diagnosis ; Evidence-Based Medicine ; Female ; Humans ; Risk Factors ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Predictive factors for response to neoadjuvant therapy in breast cancer.
Autorzy:
Loibl S; German Breast Group, Neu-Isenburg, Germany.
von Minckwitz G
Untch M
Denkert C
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Corporate Authors:
German Breast Group
Źródło:
Oncology research and treatment [Oncol Res Treat] 2014; Vol. 37 (10), pp. 563-8. Date of Electronic Publication: 2014 Sep 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Biomarkers, Tumor/*blood
Breast Neoplasms/*mortality
Breast Neoplasms/*therapy
Polymorphism, Single Nucleotide/*genetics
Age Distribution ; Breast Neoplasms/diagnosis ; Chemotherapy, Adjuvant/mortality ; Female ; Genetic Markers/genetics ; Genetic Predisposition to Disease/epidemiology ; Genetic Predisposition to Disease/genetics ; Humans ; Prevalence ; Prognosis ; Risk Factors ; Survival Rate ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prospective validation of immunological infiltrate for prediction of response to neoadjuvant chemotherapy in HER2-negative breast cancer--a substudy of the neoadjuvant GeparQuinto trial.
Autorzy:
Issa-Nummer Y; German Breast Group, Neu-Isenburg, Germany.
Darb-Esfahani S
Loibl S
Kunz G
Nekljudova V
Schrader I
Sinn BV
Ulmer HU
Kronenwett R
Just M
Kühn T
Diebold K
Untch M
Holms F
Blohmer JU
Habeck JO
Dietel M
Overkamp F
Krabisch P
von Minckwitz G
Denkert C
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Źródło:
PloS one [PLoS One] 2013 Dec 02; Vol. 8 (12), pp. e79775. Date of Electronic Publication: 2013 Dec 02 (Print Publication: 2013).
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/immunology
Breast Neoplasms*/mortality
Breast Neoplasms*/pathology
Lymphocytes*/immunology
Lymphocytes*/pathology
Neoadjuvant Therapy*
Receptor, ErbB-2*
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Adult ; Aged ; Anthracyclines/administration & dosage ; Bridged-Ring Compounds/administration & dosage ; Female ; Humans ; Middle Aged ; Prospective Studies ; Taxoids/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Two different sides of 'chemobrain': determinants and nondeterminants of self-perceived cognitive dysfunction in a prospective, randomized, multicenter study.
Autorzy:
Hermelink K; Department of Gynecology and Obstetrics, Ludwig Maximilian University, Munich, Germany. />Küchenhoff H
Untch M
Bauerfeind I
Lux MP
Bühner M
Manitz J
Fensterer V
Münzel K
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Źródło:
Psycho-oncology [Psychooncology] 2010 Dec; Vol. 19 (12), pp. 1321-8.
Typ publikacji:
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Affect*
Antineoplastic Combined Chemotherapy Protocols/*adverse effects
Breast Neoplasms/*drug therapy
Cognition/*drug effects
Cognition Disorders/*chemically induced
Adult ; Aged ; Breast Neoplasms/psychology ; Cognition Disorders/diagnosis ; Cognition Disorders/psychology ; Female ; Follow-Up Studies ; Humans ; Middle Aged ; Neuropsychological Tests ; Perception ; Prospective Studies ; Quality of Life ; Self Report
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical practice decisions in endocrine therapy.
Autorzy:
Untch M; Helios Klinikum Berlin Buch, Academic Hospital of University Charite Berlin, Berlin, Germany. Michael.untch@helios-kliniken.de
Thomssen C
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Źródło:
Cancer investigation [Cancer Invest] 2010; Vol. 28 Suppl 1, pp. 4-13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*drug therapy
Tamoxifen/*therapeutic use
Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Aromatase Inhibitors/administration & dosage ; Clinical Trials as Topic ; Female ; Humans ; Ki-67 Antigen/analysis ; Pharmacogenetics ; Practice Guidelines as Topic ; Receptors, Estrogen/analysis ; Tamoxifen/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Proceedings of the international consensus conference on breast cancer risk, genetics, & risk management, April, 2007.
Autorzy:
Schwartz GF; Jefferson Medical College, 1015 Chestnut Street, Suite 510, Philadelphia, PA 19107-4305, USA. />Hughes KS
Lynch HT
Fabian CJ
Fentiman IS
Robson ME
Domchek SM
Hartmann LC
Holland R
Winchester DJ
Anderson BO
Arun BK
Bartelink H
Bernard P
Bonanni B
Cady B
Clough KB
Feig SA
Heywang-Köbrunner SH
Howell A
Isaacs C
Kopans DB
Mansel RE
Masood S
Palazzo JP
Pressman PI
Solin LJ
Untch M
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Corporate Authors:
Consensus Conference Committee
Źródło:
The breast journal [Breast J] 2009 Jan-Feb; Vol. 15 (1), pp. 4-16.
Typ publikacji:
Journal Article
MeSH Terms:
Risk Management*
Breast Neoplasms/*etiology
Breast Neoplasms/*genetics
Estrogen Replacement Therapy/adverse effects ; Female ; Genes, BRCA1 ; Genes, BRCA2 ; Genes, p53 ; Genetic Counseling ; Humans ; Mutation ; PTEN Phosphohydrolase/genetics ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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