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Tytuł:
Correction: Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states.
Autorzy:
Heimann AS
Gupta A
Gomes I
Rahman R
Schlessinger A
Ferro ES
Unterwald EM
Devi LA
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Źródło:
PloS one [PLoS One] 2018 Feb 15; Vol. 13 (2), pp. e0193322. Date of Electronic Publication: 2018 Feb 15 (Print Publication: 2018).
Typ publikacji:
Journal Article; Published Erratum
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states.
Autorzy:
Heimann AS; Proteimax Biotechnology LTDA, Av Corifeu de Azevedo Marques, São Paulo, SP, Brazil.
Gupta A; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, United States of America.
Gomes I; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, United States of America.
Rayees R; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, United States of America.
Schlessinger A; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, United States of America.
Ferro ES; Department of Pharmacology, Biomedical Science Institute, University of São Paulo, São Paulo, SP, Brazil.
Unterwald EM; Department of Pharmacology, Temple University School of Medicine, Philadelphia, United States of America.
Devi LA; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Nov 01; Vol. 12 (11), pp. e0187306. Date of Electronic Publication: 2017 Nov 01 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies/*immunology
Receptors, G-Protein-Coupled/*immunology
Animals ; Enzyme-Linked Immunosorbent Assay ; Epitopes/chemistry ; Epitopes/immunology ; HEK293 Cells ; Humans ; Male ; Protein Conformation ; Rabbits ; Rats ; Rats, Wistar ; Receptors, G-Protein-Coupled/agonists ; Receptors, G-Protein-Coupled/antagonists & inhibitors ; Receptors, G-Protein-Coupled/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Long-term effects of chronic nicotine on emotional and cognitive behaviors and hippocampus cell morphology in mice: comparisons of adult and adolescent nicotine exposure.
Autorzy:
Holliday ED; Department of Psychology, Neuroscience Program, Temple University, Philadelphia, PA 19122, USA.
Nucero P; Center for Substance Abuse Research and Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, U.S.A.
Kutlu MG; Department of Psychology, Neuroscience Program, Temple University, Philadelphia, PA 19122, USA.
Oliver C; Department of Psychology, Neuroscience Program, Temple University, Philadelphia, PA 19122, USA.
Connelly KL; Center for Substance Abuse Research and Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, U.S.A.
Gould TJ; Department of Psychology, Neuroscience Program, Temple University, Philadelphia, PA 19122, USA.
Unterwald EM; Center for Substance Abuse Research and Department of Pharmacology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, U.S.A.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2016 Nov; Vol. 44 (10), pp. 2818-2828. Date of Electronic Publication: 2016 Oct 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Cognition/*drug effects
Depression/*etiology
Emotions/*drug effects
Hippocampus/*drug effects
Nicotine/*toxicity
Nicotinic Agonists/*toxicity
Animals ; Conditioning, Classical ; Hippocampus/cytology ; Hippocampus/growth & development ; Mice ; Mice, Inbred C57BL ; Nicotine/pharmacology ; Nicotinic Agonists/pharmacology ; Pyramidal Cells/cytology ; Pyramidal Cells/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ceftriaxone attenuates acute cocaine-evoked dopaminergic neurotransmission in the nucleus accumbens of the rat.
Autorzy:
Barr JL; Department of Pharmacology and Centre for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA, USA.
Rasmussen BA; Department of Pharmacology and Centre for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA, USA.
Tallarida CS; Department of Pharmacology and Centre for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA, USA.
Scholl JL; Centre for Brain and Behaviour Research, Division of Basic Biomedical Sciences, Sanford School of Medicine at the University of South Dakota, Vermillion, SD, USA.
Forster GL; Centre for Brain and Behaviour Research, Division of Basic Biomedical Sciences, Sanford School of Medicine at the University of South Dakota, Vermillion, SD, USA.
Unterwald EM; Department of Pharmacology and Centre for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA, USA.
Rawls SM; Department of Pharmacology and Centre for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA, USA.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2015 Nov; Vol. 172 (22), pp. 5414-24. Date of Electronic Publication: 2015 Oct 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Ceftriaxone/*pharmacology
Dopamine/*physiology
Nucleus Accumbens/*drug effects
Synaptic Transmission/*drug effects
Animals ; Cocaine ; Glycogen Synthase Kinase 3/metabolism ; Glycogen Synthase Kinase 3 beta ; Male ; Motor Activity/drug effects ; Nucleus Accumbens/metabolism ; Nucleus Accumbens/physiology ; Proto-Oncogene Proteins c-akt/metabolism ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition.
Autorzy:
Shi X; Department of Pharmacology and the Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA, 19140, USA.
Miller JS
Harper LJ
Poole RL
Gould TJ
Unterwald EM
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2014 Aug; Vol. 231 (16), pp. 3109-18. Date of Electronic Publication: 2014 Mar 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Reward*
Cocaine-Related Disorders/*psychology
Conditioning, Operant/*drug effects
Glycogen Synthase Kinase 3/*physiology
Multiprotein Complexes/*physiology
Oncogene Protein v-akt/*physiology
Signal Transduction/*drug effects
TOR Serine-Threonine Kinases/*physiology
Animals ; Cues ; Enzyme Inhibitors/pharmacology ; Fear/drug effects ; Fear/psychology ; Glycogen Synthase Kinase 3/antagonists & inhibitors ; Hippocampus/drug effects ; Hippocampus/metabolism ; Indoles/pharmacology ; Limbic System/drug effects ; Limbic System/metabolism ; Male ; Maleimides/pharmacology ; Mechanistic Target of Rapamycin Complex 1 ; Memory/drug effects ; Mice ; Neostriatum/drug effects ; Neostriatum/metabolism ; Phosphorylation ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The GSK3 signaling pathway is activated by cocaine and is critical for cocaine conditioned reward in mice.
Autorzy:
Miller JS; Department of Pharmacology and the Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America.
Barr JL; Department of Pharmacology and the Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America.
Harper LJ; Department of Pharmacology and the Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America.
Poole RL; Department of Psychology, Temple University, Philadelphia, Pennsylvania, United States of America.
Gould TJ; Department of Psychology, Temple University, Philadelphia, Pennsylvania, United States of America.
Unterwald EM; Department of Pharmacology and the Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Feb 04; Vol. 9 (2), pp. e88026. Date of Electronic Publication: 2014 Feb 04 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cocaine/*pharmacology
Conditioning, Psychological/*drug effects
Glycogen Synthase Kinase 3/*metabolism
Signal Transduction/*drug effects
Animals ; Glycogen Synthase Kinase 3 beta ; Male ; Mice ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Dopamine D1/metabolism ; Receptors, Dopamine D2/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons.
Autorzy:
Unterwald EM
Page ME
Brown TB
Miller JS
Ruiz M
Pescatore KA
Xu B
Reichardt LF
Beverley J
Tang B
Steiner H
Thomas EA
Ehrlich ME; Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, PA 19107, USA. .
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2013 Dec 26; Vol. 8, pp. 47. Date of Electronic Publication: 2013 Dec 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Behavior, Animal/*physiology
Corpus Striatum/*metabolism
Neurons/*metabolism
Receptor, trkB/*deficiency
Receptor, trkB/*genetics
Aging ; Animals ; Blotting, Western ; Female ; Gene Knockdown Techniques ; In Situ Hybridization ; Male ; Mice ; Mice, Transgenic ; Oligonucleotide Array Sequence Analysis ; Signal Transduction/genetics ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A role for delta opioid receptors in the central nucleus of the amygdala in anxiety-like behaviors.
Autorzy:
Randall-Thompson JF; Department of Pharmacology and the Center for Substance Abuse Research, Temple University School of Medicine, 3420 N. Broad Street, Philadelphia, PA 19140, USA.
Pescatore KA
Unterwald EM
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2010 Dec; Vol. 212 (4), pp. 585-95. Date of Electronic Publication: 2010 Aug 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Behavior, Animal*/drug effects
Amygdala/*metabolism
Anxiety/*metabolism
Receptors, Opioid, delta/*metabolism
Amygdala/drug effects ; Analgesics, Opioid/administration & dosage ; Animals ; Anxiety/psychology ; Dose-Response Relationship, Drug ; Enkephalin, D-Penicillamine (2,5)-/administration & dosage ; Fear/drug effects ; Male ; Microinjections ; Motor Activity/drug effects ; Naltrexone/administration & dosage ; Naltrexone/analogs & derivatives ; Narcotic Antagonists/administration & dosage ; Rats ; Rats, Sprague-Dawley ; Receptors, Opioid, delta/agonists ; Receptors, Opioid, delta/antagonists & inhibitors ; Swimming ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A role for mu opioid receptors in cocaine-induced activity, sensitization, and reward in the rat.
Autorzy:
Schroeder JA; Department of Pharmacology and the Center for Substance Abuse Research, Temple University School of Medicine, 3420 North Broad Street, Philadelphia, PA 19140, USA.
Hummel M
Simpson AD
Sheikh R
Soderman AR
Unterwald EM
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2007 Dec; Vol. 195 (2), pp. 265-72. Date of Electronic Publication: 2007 Aug 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Reward*
Behavior, Animal/*drug effects
Cocaine/*pharmacology
Motor Activity/*drug effects
Receptors, Opioid, mu/*physiology
Analysis of Variance ; Animals ; Conditioning, Operant/drug effects ; Dose-Response Relationship, Drug ; Male ; Peptide Fragments ; Peptides/administration & dosage ; Peptides/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptors, Opioid, mu/antagonists & inhibitors ; Somatostatin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 24

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