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Tytuł :
Genome-Wide Identification and Characterization of UTR-Introns of Citrus sinensis .
Autorzy :
Shi X; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Wu J; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Mensah RA; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Tian N; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Liu J; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Liu F; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Chen J; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Che J; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Guo Y; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Wu B; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Zhong G; Institute of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Cheng C; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Apr 27; Vol. 21 (9). Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Genome, Plant*
Genome-Wide Association Study*/methods
Introns*
Untranslated Regions*
Citrus sinensis/*genetics
3' Untranslated Regions ; 5' Untranslated Regions ; Alternative Splicing ; Chromosome Mapping ; Genomics/methods ; Open Reading Frames ; RNA Splice Sites ; Regulatory Sequences, Nucleic Acid
Czasopismo naukowe
Tytuł :
Nuclear export of plant pararetrovirus mRNAs involves the TREX complex, two viral proteins and the highly structured 5' leader region.
Autorzy :
Kubina J; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Geldreich A; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Gales JP; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Baumberger N; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Bouton C; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Ryabova LA; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Grasser KD; Cell Biology & Plant Biochemistry, Biochemistry Centre, University of Regensburg, D-93053 Regensburg, Germany.
Keller M; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
Dimitrova M; Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, Strasbourg, France.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Sep 07; Vol. 49 (15), pp. 8900-8922.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*
Arabidopsis Proteins/*metabolism
Cell Nucleus/*virology
RNA, Messenger/*metabolism
RNA, Viral/*metabolism
Viral Proteins/*metabolism
Active Transport, Cell Nucleus ; Arabidopsis/virology ; Arabidopsis Proteins/physiology ; Capsid Proteins/metabolism ; Caulimovirus/genetics ; Caulimovirus/metabolism ; Cell Nucleus/metabolism ; Plant Diseases/virology ; RNA, Viral/chemistry ; RNA-Directed DNA Polymerase/metabolism
Czasopismo naukowe
Tytuł :
Translational control by DHX36 binding to 5'UTR G-quadruplex is essential for muscle stem-cell regenerative functions.
Autorzy :
Chen X; Department of Orthopaedics and Traumatology, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong SAR, China.
Yuan J; Department of Chemical Pathology, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong SAR, China.
Xue G; Department of Orthopaedics and Traumatology, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong SAR, China.
Campanario S; Department of Experimental & Health Sciences, Universitat Pompeu Fabra (UPF), CIBERNED, ICREA, Barcelona, Spain.; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Wang D; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Wang W; Department of Biology, Southern University of Science and Technology, Shenzhen, China.
Mou X; Department of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Liew SW; Department of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Umar MI; Department of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Isern J; Department of Experimental & Health Sciences, Universitat Pompeu Fabra (UPF), CIBERNED, ICREA, Barcelona, Spain.; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Zhao Y; Department of Orthopaedics and Traumatology, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong SAR, China.
He L; Department of Chemical Pathology, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong SAR, China.
Li Y; Department of Orthopaedics and Traumatology, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong SAR, China.
Mann CJ; Department of Experimental & Health Sciences, Universitat Pompeu Fabra (UPF), CIBERNED, ICREA, Barcelona, Spain.
Yu X; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Wang L; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; College of Life Sciences, Xinyang Normal University, Xinyang, China.
Perdiguero E; Department of Experimental & Health Sciences, Universitat Pompeu Fabra (UPF), CIBERNED, ICREA, Barcelona, Spain.
Chen W; Department of Biology, Southern University of Science and Technology, Shenzhen, China.
Xue Y; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Nagamine Y; Friedrich Miescher Institute for Biomedical Research, Novartis Research Foundation, Basel, Switzerland.
Kwok CK; Department of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.; Shenzhen Research Institute of City University of Hong Kong, Shenzhen, China.
Sun H; Department of Chemical Pathology, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong SAR, China. .
Muñoz-Cánoves P; Department of Experimental & Health Sciences, Universitat Pompeu Fabra (UPF), CIBERNED, ICREA, Barcelona, Spain. .; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain. .
Wang H; Department of Orthopaedics and Traumatology, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong SAR, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 19; Vol. 12 (1), pp. 5043. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*
G-Quadruplexes*
DEAD-box RNA Helicases/*metabolism
Muscles/*cytology
Regeneration/*physiology
Stem Cells/*cytology
Animals ; Animals, Genetically Modified ; Cells, Cultured ; Disease Models, Animal ; GTP-Binding Protein alpha Subunit, Gi2/metabolism ; Gene Expression Regulation ; Humans ; Mice ; Muscles/metabolism ; Myoblasts/metabolism ; Polyribosomes/metabolism ; Protein Biosynthesis ; RNA, Messenger/genetics ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
Supramolecular Cylinders Target Bulge Structures in the 5' UTR of the RNA Genome of SARS-CoV-2 and Inhibit Viral Replication*.
Autorzy :
Melidis L; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Hill HJ; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Coltman NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Davies SP; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Winczura K; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Chauhan T; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Craig JS; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Garai A; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Hooper CAJ; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Egan RT; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
McKeating JA; Nuffield Department of Medicine & Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), Oxford University, Oxford, OX3 7BN, UK.
Hodges NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Stamataki Z; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Grzechnik P; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Hannon MJ; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Aug 09; Vol. 60 (33), pp. 18144-18151. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*
Antiviral Agents/*pharmacology
Macromolecular Substances/*pharmacology
RNA/*metabolism
SARS-CoV-2/*drug effects
Virus Replication/*drug effects
Animals ; Antiviral Agents/chemistry ; Antiviral Agents/metabolism ; Chlorocebus aethiops ; Coordination Complexes/chemistry ; Coordination Complexes/metabolism ; Coordination Complexes/pharmacology ; Genome, Viral/drug effects ; Macromolecular Substances/chemistry ; Macromolecular Substances/metabolism ; Metals, Heavy/chemistry ; Molecular Dynamics Simulation ; RNA/genetics ; SARS-CoV-2/chemistry ; Vero Cells
Czasopismo naukowe
Tytuł :
New markers for predictions of acute and chronic rejection and graft outcomes in kidney transplant recipients; HLA-G gene 3'UTR 14 bp polymorphism and sHLA-G.
Autorzy :
Darbas S; Department of Medical Biology and Genetics, Akdeniz University Faculty of Medicine, Antalya, Turkey. Electronic address: .
Yilmaz VT; Division of Nephrology, Department of Internal Medicine, Akdeniz University Faculty of Medicine, Antalya, Turkey; Tuncer Karpuzoglu Transplantation Center, Akdeniz University Hospital, Antalya, Turkey. Electronic address: .
Kocak H; Division of Nephrology, Department of Internal Medicine, Akdeniz University Faculty of Medicine, Antalya, Turkey; Tuncer Karpuzoglu Transplantation Center, Akdeniz University Hospital, Antalya, Turkey. Electronic address: .
Kisaoglu A; Department of General Surgery, Akdeniz University Faculty of Medicine, Antalya, Turkey; Tuncer Karpuzoglu Transplantation Center, Akdeniz University Hospital, Antalya, Turkey. Electronic address: .
Demiryilmaz I; Department of General Surgery, Akdeniz University Faculty of Medicine, Antalya, Turkey; Tuncer Karpuzoglu Transplantation Center, Akdeniz University Hospital, Antalya, Turkey. Electronic address: .
Aydinli B; Department of General Surgery, Akdeniz University Faculty of Medicine, Antalya, Turkey; Tuncer Karpuzoglu Transplantation Center, Akdeniz University Hospital, Antalya, Turkey. Electronic address: .
Arslan HS; Department of Medical Biology and Genetics, Akdeniz University Faculty of Medicine, Antalya, Turkey. Electronic address: .
Ucar F; Department of Medical Biology and Genetics, Akdeniz University Faculty of Medicine, Antalya, Turkey; Tuncer Karpuzoglu Transplantation Center, Akdeniz University Hospital, Antalya, Turkey. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jul 20; Vol. 790, pp. 145712. Date of Electronic Publication: 2021 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
3' Untranslated Regions*
Polymorphism, Genetic*
Biomarkers/*analysis
Graft Rejection/*diagnosis
HLA-G Antigens/*genetics
Kidney Transplantation/*adverse effects
Renal Insufficiency, Chronic/*surgery
Adolescent ; Adult ; Aged ; Case-Control Studies ; Female ; Graft Rejection/etiology ; Humans ; Male ; Middle Aged ; Renal Insufficiency, Chronic/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication.
Autorzy :
Akiyama BM; Department of Biochemistry and Molecular Genetics, Aurora, CO 80045, USA.
Graham ME; Department of Immunology and Microbiology, Aurora, CO 80045, USA.
O Donoghue Z; Department of Immunology and Microbiology, Aurora, CO 80045, USA.
Beckham JD; Department of Immunology and Microbiology, Aurora, CO 80045, USA.; Department of Medicine Division of Infectious Diseases, Aurora, CO 80045, USA.
Kieft JS; Department of Biochemistry and Molecular Genetics, Aurora, CO 80045, USA.; RNA BioScience Initiative, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jul 09; Vol. 49 (12), pp. 7122-7138.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
3' Untranslated Regions*
Flavivirus/*genetics
RNA, Viral/*chemistry
A549 Cells ; Base Pairing ; Base Sequence ; Conserved Sequence ; Crystallography, X-Ray ; Exoribonucleases/metabolism ; Flavivirus/physiology ; Humans ; Models, Molecular ; Nucleic Acid Conformation ; RNA, Viral/metabolism ; Virus Replication
Czasopismo naukowe
Tytuł :
Characterization of the regulatory 5'-flanking region of bovine mucin 2 (MUC2) gene.
Autorzy :
Yamashita MSA; Graduation Program in Biotechnology, Federal University of Tocantins (UFT), Gurupi, TO, Brazil. .
Vargas LN; Institute of Biotechnology, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Melo EO; Graduation Program in Biotechnology, Federal University of Tocantins (UFT), Gurupi, TO, Brazil.; EMBRAPA Genetic Resources and Biotechnology, Brasília, DF, Brazil.
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Jul; Vol. 476 (7), pp. 2847-2856. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article
MeSH Terms :
5' Untranslated Regions*
Gene Expression Regulation*
Mucin-2*/biosynthesis
Mucin-2*/genetics
Promoter Regions, Genetic*
Animals ; Cattle ; Cell Line, Tumor ; Humans
Czasopismo naukowe
Tytuł :
Non-coding region variants upstream of MEF2C cause severe developmental disorder through three distinct loss-of-function mechanisms.
Autorzy :
Wright CF; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter EX2 5DW, UK.
Quaife NM; National Heart & Lung Institute and MRC London Institute of Medical Sciences, Imperial College London, London W12 0NN, UK; Cardiovascular Research Centre, Royal Brompton & Harefield Hospitals NHS Trust, London SW3 6NP, UK.
Ramos-Hernández L; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain.
Danecek P; Human Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1RQ, UK.
Ferla MP; National Institute for Health Research Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
Samocha KE; Human Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1RQ, UK.
Kaplanis J; Human Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1RQ, UK.
Gardner EJ; Human Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1RQ, UK.
Eberhardt RY; Human Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1RQ, UK.
Chao KR; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Karczewski KJ; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Morales J; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge CB10 1SD, UK.
Gallone G; Human Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1RQ, UK.
Balasubramanian M; Sheffield Clinical Genetics Service, Sheffield Children's NHS Foundation Trust, Sheffield S10 2TH, UK; Academic Unit of Child Health, Department of Oncology & Metabolism, University of Sheffield, Sheffield S10 2TH, UK.
Banka S; Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University Hospitals NHS Foundation Trust, Health Innovation Manchester, Manchester M13 9WL, UK; Division of Evolution and Genomic Sciences, School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, UK.
Gompertz L; Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University Hospitals NHS Foundation Trust, Health Innovation Manchester, Manchester M13 9WL, UK.
Kerr B; Division of Evolution and Genomic Sciences, School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, UK.
Kirby A; Department of Pediatrics, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA.
Lynch SA; UCD Academic Centre on Rare Diseases, School of Medicine and Medical Sciences, University College Dublin, and Clinical Genetics, Temple Street Children's University Hospital, Dublin D01 XD99, Ireland.
Morton JEV; West Midlands Regional Clinical Genetics Service and Birmingham Health Partners, Birmingham Women's and Children's Hospitals NHS Foundation Trust, Birmingham B4 6NH, UK.
Pinz H; Department of Pediatrics, Saint Louis University School of Medicine, Saint Louis, MO 63104, USA.
Sansbury FH; All Wales Medical Genomics Service, NHS Wales Cardiff and Vale University Health Board, Institute of Medical Genetics, University Hospital of Wales, Cardiff CF14 4AY, UK.
Stewart H; Oxford Centre for Genomic Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LE, UK.
Zuccarelli BD; Department of Neurology, University of Kansas School of Medicine-Salina Campus, Salina, KS 67401, USA.
Cook SA; National Heart & Lung Institute and MRC London Institute of Medical Sciences, Imperial College London, London W12 0NN, UK.
Taylor JC; National Institute for Health Research Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
Juusola J; GeneDx, Gaithersburg, MD 20877, USA.
Retterer K; GeneDx, Gaithersburg, MD 20877, USA.
Firth HV; Human Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1RQ, UK; East Anglian Medical Genetics Service, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
Hurles ME; Human Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1RQ, UK.
Lara-Pezzi E; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain; CIBER de enfermedades CardioVasculares (CIBERCV), 28029 Madrid, Spain.
Barton PJR; National Heart & Lung Institute and MRC London Institute of Medical Sciences, Imperial College London, London W12 0NN, UK; Cardiovascular Research Centre, Royal Brompton & Harefield Hospitals NHS Trust, London SW3 6NP, UK.
Whiffin N; Human Genetics Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1RQ, UK; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK. Electronic address: .
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Corporate Authors :
Genomics England Research Consortium
Źródło :
American journal of human genetics [Am J Hum Genet] 2021 Jun 03; Vol. 108 (6), pp. 1083-1094. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*
Genetic Predisposition to Disease*
Loss of Function Mutation*
Developmental Disabilities/*etiology
Child ; Cohort Studies ; DNA Copy Number Variations ; Developmental Disabilities/pathology ; Humans ; MEF2 Transcription Factors/genetics ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Interrogating the 5'UTR tandem repeats of retrotransposon roo of Drosophila about horizontal transfer.
Autorzy :
Domínguez A; Departamento de Biología Funcional, Área de Genética, Universidad de Oviedo, 33071, Oviedo, Spain. .
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Źródło :
Genetica [Genetica] 2021 Jun; Vol. 149 (3), pp. 171-177. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
5' Untranslated Regions*
Gene Transfer, Horizontal*
Retroelements/*genetics
Animals ; Drosophila melanogaster ; Evolution, Molecular ; Gene Duplication ; Tandem Repeat Sequences
Czasopismo naukowe
Tytuł :
Annotating high-impact 5'untranslated region variants with the UTRannotator.
Autorzy :
Zhang X; National Heart and Lung Institute and MRC London Institute of Medical Science, Imperial College London, London W12 0NN, UK.; Royal Brompton Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London SW3 6NP, UK.
Wakeling M; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter EX1 2LU, UK.
Ware J; National Heart and Lung Institute and MRC London Institute of Medical Science, Imperial College London, London W12 0NN, UK.; Royal Brompton Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London SW3 6NP, UK.
Whiffin N; National Heart and Lung Institute and MRC London Institute of Medical Science, Imperial College London, London W12 0NN, UK.; Royal Brompton Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London SW3 6NP, UK.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2021 May 23; Vol. 37 (8), pp. 1171-1173.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*/genetics
Software*
Humans ; Molecular Sequence Annotation ; Open Reading Frames/genetics
Czasopismo naukowe
Tytuł :
DDX3 depletion represses translation of mRNAs with complex 5' UTRs.
Autorzy :
Calviello L; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.
Venkataramanan S; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.
Rogowski KJ; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.
Wyler E; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.
Wilkins K; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.
Tejura M; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.
Thai B; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.
Krol J; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.
Filipowicz W; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Landthaler M; Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.; IRI Life Sciences, Institut für Biologie, Humboldt Universität zu Berlin, Philippstraße 13, 10115 Berlin, Germany.
Floor SN; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 May 21; Vol. 49 (9), pp. 5336-5350.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*
Protein Biosynthesis*
DEAD-box RNA Helicases/*physiology
DEAD-box RNA Helicases/genetics ; DEAD-box RNA Helicases/metabolism ; HEK293 Cells ; Humans ; Mutation ; RNA, Messenger/metabolism ; RNA, Ribosomal/metabolism ; RNA, Small Interfering
Czasopismo naukowe
Tytuł :
The Detection and Bioinformatic Analysis of Alternative 3 UTR Isoforms as Potential Cancer Biomarkers.
Autorzy :
Kandhari N; Development and Stem Cells Program, Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia.
Kraupner-Taylor CA; Development and Stem Cells Program, Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia.
Harrison PF; Development and Stem Cells Program, Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia.; Monash Bioinformatics Platform, Monash University, Melbourne, VIC 3800, Australia.
Powell DR; Monash Bioinformatics Platform, Monash University, Melbourne, VIC 3800, Australia.
Beilharz TH; Development and Stem Cells Program, Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 18; Vol. 22 (10). Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
3' Untranslated Regions*
Biomarkers, Tumor/*genetics
Alternative Splicing ; Biomarkers, Tumor/metabolism ; Computational Biology ; Databases, Nucleic Acid ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; High-Throughput Nucleotide Sequencing ; Humans ; Neoplasms/diagnosis ; Neoplasms/genetics ; Neoplasms/metabolism ; Polyadenylation ; RNA Splice Sites ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA-Seq ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Predicting mean ribosome load for 5'UTR of any length using deep learning.
Autorzy :
Karollus A; Department of Informatics, Technical University of Munich, Garching, Germany.
Avsec Ž; Department of Informatics, Technical University of Munich, Garching, Germany.; Graduate School of Quantitative Biosciences (QBM), Ludwig-Maximilians-Universität München, Munich, Germany.
Gagneur J; Department of Informatics, Technical University of Munich, Garching, Germany.; Institute of Human Genetics, Technical University of Munich, Munich, Germany.; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2021 May 10; Vol. 17 (5), pp. e1008982. Date of Electronic Publication: 2021 May 10 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*
Deep Learning*
Ribosomes/*metabolism
Humans ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
An RNA-binding protein complex regulates the purine-dependent expression of a nucleobase transporter in trypanosomes.
Autorzy :
Rico-Jiménez M; Instituto de Parasitología y Biomedicina 'López-Neyra', IPBLN-CSIC, Parque Tecnológico de Ciencias de la Salud, Avda. del Conocimiento 17, 18016 Armilla, Granada, Spain.
Ceballos-Pérez G; Instituto de Parasitología y Biomedicina 'López-Neyra', IPBLN-CSIC, Parque Tecnológico de Ciencias de la Salud, Avda. del Conocimiento 17, 18016 Armilla, Granada, Spain.
Gómez-Liñán C; Instituto de Parasitología y Biomedicina 'López-Neyra', IPBLN-CSIC, Parque Tecnológico de Ciencias de la Salud, Avda. del Conocimiento 17, 18016 Armilla, Granada, Spain.
Estévez AM; Instituto de Parasitología y Biomedicina 'López-Neyra', IPBLN-CSIC, Parque Tecnológico de Ciencias de la Salud, Avda. del Conocimiento 17, 18016 Armilla, Granada, Spain.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Apr 19; Vol. 49 (7), pp. 3814-3825.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
3' Untranslated Regions*
Protozoan Proteins/*metabolism
RNA-Binding Proteins/*metabolism
Trypanosoma brucei brucei/*genetics
Gene Expression Regulation
Czasopismo naukowe
Tytuł :
Association of ST6GAL1 and CYP19A1 polymorphisms in the 3'-UTR with astrocytoma risk and prognosis in a Chinese Han population.
Autorzy :
Wang T; Department of Neurosurgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Sun Y; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an, 710069, China.
Xiong Z; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an, 710069, China.
Wu J; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an, 710069, China.
Ding X; Department of Neurosurgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Guo X; Department of Neurosurgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Shao Y; Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, 277 YanTa West Road, Xi'an, 710061, Shaanxi, China. .
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Źródło :
BMC cancer [BMC Cancer] 2021 Apr 09; Vol. 21 (1), pp. 391. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
3' Untranslated Regions*
Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide*
Antigens, CD/*genetics
Aromatase/*genetics
Astrocytoma/*epidemiology
Astrocytoma/*genetics
Sialyltransferases/*genetics
Adult ; Alleles ; Asian Continental Ancestry Group/genetics ; Astrocytoma/mortality ; Astrocytoma/therapy ; Case-Control Studies ; China/epidemiology ; Female ; Gene Frequency ; Genotype ; Humans ; Male ; Middle Aged ; Prognosis ; Risk Assessment ; Risk Factors ; Survival Analysis
Czasopismo naukowe
Tytuł :
RNA thermoswitches modulate Staphylococcus aureus adaptation to ambient temperatures.
Autorzy :
Catalan-Moreno A; Instituto de Agrobiotecnología, IdAB, CSIC-Gobierno de Navarra, Avda. de Pamplona 123, 31192 Mutilva, Navarra, Spain.
Cela M; Instituto de Agrobiotecnología, IdAB, CSIC-Gobierno de Navarra, Avda. de Pamplona 123, 31192 Mutilva, Navarra, Spain.
Menendez-Gil P; Instituto de Agrobiotecnología, IdAB, CSIC-Gobierno de Navarra, Avda. de Pamplona 123, 31192 Mutilva, Navarra, Spain.
Irurzun N; Instituto de Agrobiotecnología, IdAB, CSIC-Gobierno de Navarra, Avda. de Pamplona 123, 31192 Mutilva, Navarra, Spain.
Caballero CJ; Instituto de Agrobiotecnología, IdAB, CSIC-Gobierno de Navarra, Avda. de Pamplona 123, 31192 Mutilva, Navarra, Spain.
Caldelari I; Architecture et Réactivité de l'ARN, Université de Strasbourg, CNRS, UPR 9002, F-67000 Strasbourg, France.
Toledo-Arana A; Instituto de Agrobiotecnología, IdAB, CSIC-Gobierno de Navarra, Avda. de Pamplona 123, 31192 Mutilva, Navarra, Spain.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Apr 06; Vol. 49 (6), pp. 3409-3426.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*
Gene Expression Regulation, Bacterial*
Temperature*
Staphylococcus aureus/*genetics
Adaptation, Physiological/genetics ; Bacterial Proteins/biosynthesis ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Heat-Shock Proteins/biosynthesis ; Heat-Shock Proteins/genetics ; Mutation ; Nucleic Acid Conformation ; Staphylococcus aureus/metabolism
Czasopismo naukowe
Tytuł :
Secondary structure of the SARS-CoV-2 5'-UTR.
Autorzy :
Miao Z; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, UK.; Translational Research Institute of Brain and Brain-Like Intelligence and Department of Anesthesiology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Tidu A; Architecture Et Réactivité De l'ARN, Université De Strasbourg, Institut De Biologie Moléculaire Et Cellulaire Du CNRS, Strasbourg, France.
Eriani G; Architecture Et Réactivité De l'ARN, Université De Strasbourg, Institut De Biologie Moléculaire Et Cellulaire Du CNRS, Strasbourg, France.
Martin F; Architecture Et Réactivité De l'ARN, Université De Strasbourg, Institut De Biologie Moléculaire Et Cellulaire Du CNRS, Strasbourg, France.
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Źródło :
RNA biology [RNA Biol] 2021 Apr; Vol. 18 (4), pp. 447-456. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*
RNA, Viral/*chemistry
SARS-CoV-2/*genetics
Codon, Terminator ; Endoribonucleases/chemistry ; Endoribonucleases/metabolism ; Nucleic Acid Conformation ; RNA, Viral/metabolism ; Viral Nonstructural Proteins/genetics
Czasopismo naukowe
Tytuł :
N chemical shift assignment of the stem-loop 5a from the 5'-UTR of SARS-CoV-2.
Autorzy :
Schnieders R; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Peter SA; Department of Biology, Technical University of Darmstadt, Schnittspahnstr. 10, 64287, Darmstadt, Germany.
Banijamali E; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Biomedicum, Solnavägen 9, 17177, Stockholm, Sweden.
Riad M; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Biomedicum, Solnavägen 9, 17177, Stockholm, Sweden.
Altincekic N; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Bains JK; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Ceylan B; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Fürtig B; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Grün JT; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Hengesbach M; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Hohmann KF; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Hymon D; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Knezic B; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Oxenfarth A; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Petzold K; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Biomedicum, Solnavägen 9, 17177, Stockholm, Sweden.
Qureshi NS; EMBL Heidelberg, Meyerhofstraße 1, 69117, Heidelberg, Germany.
Richter C; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Schlagnitweit J; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Biomedicum, Solnavägen 9, 17177, Stockholm, Sweden.
Schlundt A; Institute for Molecular Biosciences, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Schwalbe H; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany. .; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany. .
Stirnal E; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Sudakov A; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Vögele J; Institute for Molecular Biosciences, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Wacker A; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Weigand JE; Department of Biology, Technical University of Darmstadt, Schnittspahnstr. 10, 64287, Darmstadt, Germany.
Wirmer-Bartoschek J; Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 7, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
Wöhnert J; Institute for Molecular Biosciences, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.; Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438, Frankfurt/M., Germany.
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Źródło :
Biomolecular NMR assignments [Biomol NMR Assign] 2021 Apr; Vol. 15 (1), pp. 203-211. Date of Electronic Publication: 2021 Jan 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
5' Untranslated Regions*
Magnetic Resonance Spectroscopy*
Coronavirus Papain-Like Proteases/*chemistry
SARS-CoV-2/*chemistry
SARS-CoV-2/*genetics
Carbon Isotopes ; Genes, Viral ; Hydrogen ; Nitrogen Isotopes ; Protein Binding ; Protein Domains ; Protein Structure, Secondary
Czasopismo naukowe
Tytuł :
Targeted editing of tomato carotenoid isomerase reveals the role of 5' UTR region in gene expression regulation.
Autorzy :
Lakshmi Jayaraj K; AgriGenome Labs Pvt Ltd, 501, 5th Floor, SCK01 Building, SmartCity Kochi, Kakkanad, Kochi, 682042, India.
Thulasidharan N; AgriGenome Labs Pvt Ltd, 501, 5th Floor, SCK01 Building, SmartCity Kochi, Kakkanad, Kochi, 682042, India.
Antony A; SciGenom Labs Pvt. Ltd, Plot no: 43A, SDF, 3rd floor, A Block, CSEZ, Kakkanad, Kochi, 682037, India.
John M; SciGenom Labs Pvt. Ltd, Plot no: 43A, SDF, 3rd floor, A Block, CSEZ, Kakkanad, Kochi, 682037, India.
Augustine R; AgriGenome Labs Pvt Ltd, 501, 5th Floor, SCK01 Building, SmartCity Kochi, Kakkanad, Kochi, 682042, India.
Chakravartty N; AgriGenome Labs Pvt. Ltd., DS-10, The Sustainability Innovation Centre (SINC), IKP Knowledge Park, Genome Valley, Hyderabad, 500078, India.
Sukumaran S; AgriGenome Labs Pvt Ltd, 501, 5th Floor, SCK01 Building, SmartCity Kochi, Kakkanad, Kochi, 682042, India.
Uma Maheswari M; AgriGenome Labs Pvt Ltd, 501, 5th Floor, SCK01 Building, SmartCity Kochi, Kakkanad, Kochi, 682042, India.
Abraham S; SciGenom Labs Pvt. Ltd, Plot no: 43A, SDF, 3rd floor, A Block, CSEZ, Kakkanad, Kochi, 682037, India.
Thomas G; AgriGenome Labs Pvt Ltd, 501, 5th Floor, SCK01 Building, SmartCity Kochi, Kakkanad, Kochi, 682042, India.; SciGenom Research Foundation, 3rd Floor, Narayana Nethralaya Building, Narayana Health City, Bangalore, 560099, India.
Lachagari VBR; AgriGenome Labs Pvt. Ltd., DS-10, The Sustainability Innovation Centre (SINC), IKP Knowledge Park, Genome Valley, Hyderabad, 500078, India.
Seshagiri S; SciGenom Research Foundation, 3rd Floor, Narayana Nethralaya Building, Narayana Health City, Bangalore, 560099, India.
Narayanan S; AgriGenome Labs Pvt Ltd, 501, 5th Floor, SCK01 Building, SmartCity Kochi, Kakkanad, Kochi, 682042, India.
Kuriakose B; AgriGenome Labs Pvt Ltd, 501, 5th Floor, SCK01 Building, SmartCity Kochi, Kakkanad, Kochi, 682042, India. .; SciGenom Research Foundation, 3rd Floor, Narayana Nethralaya Building, Narayana Health City, Bangalore, 560099, India. .
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Źródło :
Plant cell reports [Plant Cell Rep] 2021 Apr; Vol. 40 (4), pp. 621-635. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
5' Untranslated Regions*
Lycopersicon esculentum/*genetics
Plant Proteins/*genetics
cis-trans-Isomerases/*genetics
Agrobacterium/genetics ; Carotenoids/metabolism ; Chlorophyll/genetics ; Chlorophyll/metabolism ; Gene Editing/methods ; Gene Expression Regulation, Plant ; Lycopene/metabolism ; Lycopersicon esculentum/physiology ; Mutation ; Plant Leaves/genetics ; Plant Leaves/metabolism ; Plant Proteins/metabolism ; Plants, Genetically Modified ; cis-trans-Isomerases/metabolism
Czasopismo naukowe
Tytuł :
The Untranslated Regions of mRNAs in Cancer.
Autorzy :
Schuster SL; Molecular and Cellular Biology, University of Washington, Seattle, WA 98195, USA; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Hsieh AC; Molecular and Cellular Biology, University of Washington, Seattle, WA 98195, USA; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA; School of Medicine and Genome Sciences, University of Washington, Seattle, WA 98195, USA. Electronic address: .
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Źródło :
Trends in cancer [Trends Cancer] 2019 Apr; Vol. 5 (4), pp. 245-262. Date of Electronic Publication: 2019 Mar 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Genetic Predisposition to Disease*
Untranslated Regions*
Neoplasms/*genetics
RNA, Messenger/*genetics
3' Untranslated Regions ; 5' Untranslated Regions ; Animals ; Binding Sites ; Genetic Association Studies ; Humans ; Internal Ribosome Entry Sites ; MicroRNAs/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Polyadenylation ; Protein Biosynthesis ; Regulatory Sequences, Ribonucleic Acid
Czasopismo naukowe

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