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Tytuł :
Prognostic Value of Fractional Excretion of Urea Nitrogen at Discharge in Acute Decompensated Heart Failure.
Autorzy :
Nogi K; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Kawakami R; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Ueda T; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Nogi M; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Ishihara S; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Nakada Y; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Hashimoto Y; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Nakagawa H; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Nishida T; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Seno A; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Onoue K; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Soeda T; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Watanabe M; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
Saito Y; Department of Cardiovascular Medicine Nara Medical University Kashihara Japan.
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Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2021 Aug 17; Vol. 10 (16), pp. e020480. Date of Electronic Publication: 2021 Aug 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Urea Nitrogen*
Patient Discharge*
Creatinine/*metabolism
Heart Failure/*metabolism
Urea/*metabolism
Acute Disease ; Aged ; Aged, 80 and over ; Biomarkers/blood ; Biomarkers/urine ; Creatinine/blood ; Creatinine/urine ; Disease Progression ; Diuretics/therapeutic use ; Female ; Heart Failure/diagnosis ; Heart Failure/drug therapy ; Heart Failure/mortality ; Humans ; Male ; Patient Readmission ; Predictive Value of Tests ; Prognosis ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Urea/blood ; Urea/urine
Czasopismo naukowe
Tytuł :
Does admission order form design really matter? A reduction in urea blood test ordering.
Autorzy :
Mathura P; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Boettger C; Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada .
Hagtvedt R; Alberta School of Business, University of Alberta, Edmonton, Alberta, Canada.
Suranyi Y; Emergency Department, University of Alberta Hospital, Edmonton, Alberta, Canada.
Kassam N; Medicine, University of Alberta, Edmonton, Alberta, Canada.
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Źródło :
BMJ open quality [BMJ Open Qual] 2021 Jul; Vol. 10 (3).
Typ publikacji :
Journal Article
MeSH Terms :
General Practitioners*
Urea*
Blood Urea Nitrogen ; Hematologic Tests ; Hospitals, Teaching ; Humans
Czasopismo naukowe
Tytuł :
The context-specific roles of urea cycle enzymes in tumorigenesis.
Autorzy :
Hajaj E; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
Sciacovelli M; Medical Research Council Cancer Unit, University of Cambridge, Box 197, Biomedical Campus, Cambridge CB2 0XZ, UK.
Frezza C; Medical Research Council Cancer Unit, University of Cambridge, Box 197, Biomedical Campus, Cambridge CB2 0XZ, UK. Electronic address: .
Erez A; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Sep 16; Vol. 81 (18), pp. 3749-3759. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Carcinogenesis/*metabolism
Cell Transformation, Neoplastic/*metabolism
Urea/*metabolism
Ammonia/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Gene Expression/genetics ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Urea Cycle Disorders, Inborn/metabolism ; Urea Cycle Disorders, Inborn/physiopathology
Czasopismo naukowe
Tytuł :
Routine online assessment of dialysis dose: Ionic dialysance or UV-absorbance monitoring?
Autorzy :
Petitclerc T; Hemodialysis centers, AURA, Paris, France.
Ridel C; Hemodialysis centers, AURA, Paris, France.
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Źródło :
Seminars in dialysis [Semin Dial] 2021 Mar; Vol. 34 (2), pp. 116-122. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Renal Dialysis*
Urea*
Blood Urea Nitrogen ; Dialysis Solutions ; Female ; Humans ; Ions ; Male ; Monitoring, Physiologic
Czasopismo naukowe
Tytuł :
Evaluation of Residual Kidney Function during Once-Weekly Incremental Hemodialysis.
Autorzy :
Bolasco P; Treatment Study Group of Chronic Renal Disease of Italian Society of Nephrology, Italy Official Nephrologist Consultant of Regional Health Institution of Sardinia, Cagliari, Italy, .
Casula L; Department of Public Health, Clinical and Molecular Medicine-University of Cagliari, Cagliari, Italy.
Contu R; Department of Hemodialysis, ASSL di Cagliari, Cagliari, Italy.
Cadeddu M; Department of Hemodialysis, ASSL di Cagliari, Cagliari, Italy.
Murtas S; Department of Hemodialysis, ASSL di Cagliari, Cagliari, Italy.
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Źródło :
Blood purification [Blood Purif] 2021; Vol. 50 (2), pp. 246-253. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Urea Nitrogen*
Renal Dialysis*
Creatine/*blood
Kidney/*physiopathology
Aged ; Aged, 80 and over ; Creatine/urine ; Female ; Glomerular Filtration Rate ; Humans ; Kidney Failure, Chronic/blood ; Kidney Failure, Chronic/physiopathology ; Kidney Failure, Chronic/urine ; Male ; Middle Aged ; Urea/blood ; Urea/urine
Czasopismo naukowe
Tytuł :
Fifteen years of urea cycle disorders brain research: Looking back, looking forward.
Autorzy :
Sen K; Division of Neurogenetics and Neurodevelopmental Pediatrics, Children's National Hospital, Washington D.C., United States.
Whitehead M; Division of Radiology, Children's National Hospital, Washington D.C., United States.
Castillo Pinto C; Division of Neurology, Children's National Hospital, Washington D.C., United States.
Caldovic L; Childrens' Research Institute, Children's National Hospital, Washington D.C., United States.
Gropman A; Division of Neurogenetics and Neurodevelopmental Pediatrics, Children's National Hospital, Washington D.C., United States. Electronic address: .
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Źródło :
Analytical biochemistry [Anal Biochem] 2022 Jan 01; Vol. 636, pp. 114343. Date of Electronic Publication: 2021 Oct 09.
Typ publikacji :
Historical Article; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Brain*/diagnostic imaging
Brain*/metabolism
Brain*/physiopathology
Electroencephalography*
Hyperammonemia*/diagnostic imaging
Hyperammonemia*/history
Hyperammonemia*/metabolism
Hyperammonemia*/physiopathology
Magnetic Resonance Imaging*
Proton Magnetic Resonance Spectroscopy*
Urea Cycle Disorders, Inborn*/diagnostic imaging
Urea Cycle Disorders, Inborn*/history
Urea Cycle Disorders, Inborn*/metabolism
Urea Cycle Disorders, Inborn*/physiopathology
Animals ; History, 21st Century
Czasopismo naukowe
Tytuł :
Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicity and CDK inhibitory activities.
Autorzy :
Shawky AM; Science and Technology Unit (STU), Umm Al-Qura University, Makkah, Saudi Arabia.
Ibrahim NA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Abourehab MAS; Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Abdalla AN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Gouda AM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.; Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 15-33.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Docking Simulation*
Antineoplastic Agents/*pharmacology
Cyclin-Dependent Kinase 2/*antagonists & inhibitors
Protein Kinase Inhibitors/*pharmacology
Pyrroles/*pharmacology
Urea/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cyclin-Dependent Kinase 2/metabolism ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Pyrroles/chemical synthesis ; Pyrroles/chemistry ; Structure-Activity Relationship ; Urea/analogs & derivatives ; Urea/chemistry
Czasopismo naukowe
Tytuł :
Synthesis, biological activities and docking studies of pleuromutilin derivatives with piperazinyl urea linkage.
Autorzy :
Zhang Y; Department of Chemistry, School of Science, Xihua University, Chengdu, China.; Yibin Key Laboratory of Research and Application of Small Organic Chiral Molecules, Yibin Research Institute of Xihua University, Yibin, China.
Xie C; Department of Chemistry, School of Science, Xihua University, Chengdu, China.
Liu Y; Department of Chemistry, School of Science, Xihua University, Chengdu, China.
Shang F; Department of Chemistry, School of Science, Xihua University, Chengdu, China.
Shao R; Department of Chemistry, School of Science, Xihua University, Chengdu, China.
Yu J; Kampo Medicine Pharmacology Research Laboratory, Graduate School of Pharmaceutical Sciences, Yokohama University of Pharmacy, Yokohama-shi, Japan.
Wu C; Department of Chemistry, School of Science, Xihua University, Chengdu, China.
Yao X; Department of Chemistry, School of Science, Xihua University, Chengdu, China.
Liu D; Department of Chemistry, School of Science, Xihua University, Chengdu, China.
Wang Z; Department of Chemistry, School of Science, Xihua University, Chengdu, China.; Yibin Key Laboratory of Research and Application of Small Organic Chiral Molecules, Yibin Research Institute of Xihua University, Yibin, China.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 764-775.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Docking Simulation*
Anti-Bacterial Agents/*pharmacology
Diterpenes/*pharmacology
Methicillin-Resistant Staphylococcus aureus/*drug effects
Polycyclic Compounds/*pharmacology
Urea/*pharmacology
Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Diterpenes/chemical synthesis ; Diterpenes/chemistry ; HEK293 Cells ; Humans ; Microbial Sensitivity Tests ; Molecular Structure ; Polycyclic Compounds/chemical synthesis ; Polycyclic Compounds/chemistry ; Urea/analogs & derivatives ; Urea/chemistry
Czasopismo naukowe
Tytuł :
Thiophen urea derivatives as a new class of hepatitis C virus entry inhibitors.
Autorzy :
Ryu HC; R&D Center, J2H Biotech, Suwon, Gyeonggi-do, Republic of Korea.
Windisch M; Medicinal Chemistry, Institut Pasteur Korea, Seongnam, Gyeonggi-do, Republic of Korea.
Lim JW; R&D Center, J2H Biotech, Suwon, Gyeonggi-do, Republic of Korea.
Choi I; Medicinal Chemistry, Institut Pasteur Korea, Seongnam, Gyeonggi-do, Republic of Korea.
Lee EK; Institute of Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do, Republic of Korea.
Yoo HH; Institute of Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do, Republic of Korea.
Kim TK; College of Science and Engineering, Jungwon University, Geosan-gun, Chungbuk, Republic of Korea.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 462-468.
Typ publikacji :
Journal Article; Retracted Publication
MeSH Terms :
Antiviral Agents/*pharmacology
Hepacivirus/*drug effects
Thiophenes/*pharmacology
Urea/*pharmacology
Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Dose-Response Relationship, Drug ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship ; Thiophenes/chemical synthesis ; Thiophenes/chemistry ; Urea/analogs & derivatives ; Urea/chemistry ; Viral Envelope Proteins/antagonists & inhibitors ; Viral Envelope Proteins/metabolism ; Virus Internalization/drug effects
Czasopismo naukowe
Tytuł :
The addition of magnesium sulfate and borax to urea reduced soil NH 3 emissions but increased N 2 O emissions from soil with grass.
Autorzy :
Wang H; Department of Crop Science, Section of Plant Nutrition and Crop Physiology, University of Göttingen, Carl-Sprengel-Weg 1, 37075 Göttingen, Germany. Electronic address: .
Oertelt L; Department of Crop Science, Section of Plant Nutrition and Crop Physiology, University of Göttingen, Carl-Sprengel-Weg 1, 37075 Göttingen, Germany.
Dittert K; Department of Crop Science, Section of Plant Nutrition and Crop Physiology, University of Göttingen, Carl-Sprengel-Weg 1, 37075 Göttingen, Germany.
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Źródło :
The Science of the total environment [Sci Total Environ] 2022 Jan 10; Vol. 803, pp. 149902. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Soil*
Urea*
Agriculture ; Borates ; Fertilizers/analysis ; Magnesium Sulfate ; Nitrogen/analysis ; Nitrous Oxide/analysis ; Poaceae
Czasopismo naukowe
Tytuł :
Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects.
Autorzy :
AlNajjar YT; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, 11835, Egypt.
Gabr M; Department of Radiology, Stanford University, CA, 94305, United States.
ElHady AK; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, 11835, Egypt; School of Life and Medical Sciences, University of Hertfordshire Hosted by Global Academic Foundation, New Administrative Capital, Cairo, Egypt.
Salah M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, October University for Modern Sciences and Arts, Cairo, 12451, Egypt.
Wilms G; Institute of Pharmacology and Toxicology, Medical Faculty of the RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.
Abadi AH; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, 11835, Egypt.
Becker W; Institute of Pharmacology and Toxicology, Medical Faculty of the RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.
Abdel-Halim M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, 11835, Egypt. Electronic address: .
Engel M; Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2.3, D-66123, Saarbrücken, Germany. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2022 Jan 05; Vol. 227, pp. 113911. Date of Electronic Publication: 2021 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Discovery*
Neuroprotective Agents/*pharmacology
Protein Serine-Threonine Kinases/*antagonists & inhibitors
Protein-Tyrosine Kinases/*antagonists & inhibitors
Thiazoles/*pharmacology
Urea/*pharmacology
alpha-Synuclein/*antagonists & inhibitors
Cell Survival/drug effects ; Dose-Response Relationship, Drug ; HEK293 Cells ; Humans ; Molecular Structure ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; Protein Aggregates/drug effects ; Protein Serine-Threonine Kinases/metabolism ; Protein-Tyrosine Kinases/metabolism ; Structure-Activity Relationship ; Thiazoles/chemical synthesis ; Thiazoles/chemistry ; Urea/analogs & derivatives ; Urea/chemistry ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Pimavanserin for negative symptoms of schizophrenia: results from the ADVANCE phase 2 randomised, placebo-controlled trial in North America and Europe.
Autorzy :
Bugarski-Kirola D; Acadia Pharmaceuticals GmbH, Basel, Switzerland. Electronic address: .
Arango C; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM. CIBERSAM, Universidad Complutense, School of Medicine, Madrid, Spain.
Fava M; Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Nasrallah H; University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Liu IY; Acadia Pharmaceuticals, San Diego, CA, USA.
Abbs B; Acadia Pharmaceuticals, San Diego, CA, USA.
Stankovic S; Acadia Pharmaceuticals, San Diego, CA, USA.
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Źródło :
The lancet. Psychiatry [Lancet Psychiatry] 2022 Jan; Vol. 9 (1), pp. 46-58. Date of Electronic Publication: 2021 Nov 30.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Piperidines/*pharmacology
Schizophrenia/*drug therapy
Schizophrenia/*physiopathology
Serotonin 5-HT2 Receptor Antagonists/*pharmacology
Urea/*analogs & derivatives
Adolescent ; Adult ; Double-Blind Method ; Europe ; Female ; Humans ; Male ; Middle Aged ; North America ; Outcome Assessment, Health Care ; Piperidines/administration & dosage ; Piperidines/adverse effects ; Serotonin 5-HT2 Receptor Antagonists/administration & dosage ; Serotonin 5-HT2 Receptor Antagonists/adverse effects ; Urea/administration & dosage ; Urea/adverse effects ; Urea/pharmacology ; Young Adult
Czasopismo naukowe
Tytuł :
Potentiometric urea biosensors.
Autorzy :
Özbek O; Science and Technology, Application and Research Center, Zonguldak Bülent Ecevit University, 67600 Zonguldak, Turkey. Electronic address: .
Berkel C; Department of Molecular Biology and Genetics, Faculty of Science and Arts, Tokat Gaziosmanpasa University, 60250 Tokat, Turkey. Electronic address: .
Isildak Ö; Department of Chemistry, Faculty of Science and Arts, Tokat Gaziosmanpasa University, 60250 Tokat, Turkey.
Isildak I; Department of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, 34220 Istanbul, Turkey.
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Źródło :
Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2022 Jan 01; Vol. 524, pp. 154-163. Date of Electronic Publication: 2021 Nov 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biosensing Techniques*
Urea*
Humans ; Urease
Czasopismo naukowe
Tytuł :
Synthesis, functional proteomics and biological evaluation of new 5-pyrazolyl ureas as potential anti-angiogenic compounds.
Autorzy :
Morretta E; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 84084, Fisciano, Salerno, Italy.
Sidibè A; Department of Cell Physiology and Metabolism, University of Geneva, Rue Michel-Servet 1, CH - 1211, Geneva, Switzerland.
Spallarossa A; Department of Pharmacy, School of Medical and Pharmaceutical Sciences, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.
Petrella A; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 84084, Fisciano, Salerno, Italy.
Meta E; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Vlaams Instituut voor Biotechnologie, Leuven, Belgium.
Bruno O; Department of Pharmacy, School of Medical and Pharmaceutical Sciences, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.
Monti MC; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 84084, Fisciano, Salerno, Italy.
Brullo C; Department of Pharmacy, School of Medical and Pharmaceutical Sciences, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Dec 15; Vol. 226, pp. 113872. Date of Electronic Publication: 2021 Sep 25.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors/*pharmacology
Neovascularization, Physiologic/*drug effects
Pyrazoles/*pharmacology
Urea/*pharmacology
Angiogenesis Inhibitors/chemical synthesis ; Angiogenesis Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Humans ; Molecular Structure ; Protein Phosphatase 1/antagonists & inhibitors ; Protein Phosphatase 1/metabolism ; Proteolysis/drug effects ; Pyrazoles/chemical synthesis ; Pyrazoles/chemistry ; Structure-Activity Relationship ; Urea/analogs & derivatives ; Urea/chemistry
Czasopismo naukowe
Tytuł :
Novel diarylamides and diarylureas with N-substitution dependent activity against medulloblastoma.
Autorzy :
Lawson C; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, Lancashire, PR1 2HE, UK.
Ahmed Alta TB; School of Science, Engineering and Environment, University of Salford, Salford, M5 4WT, UK.
Moschou G; School of Science, Engineering and Environment, University of Salford, Salford, M5 4WT, UK.
Skamnaki V; Department of Biochemistry and Biotechnology, University of Thessaly, Biopolis, 41500, Larisa, Greece.
Solovou TGA; Department of Biochemistry and Biotechnology, University of Thessaly, Biopolis, 41500, Larisa, Greece.
Topham C; School of Science, Engineering and Environment, University of Salford, Salford, M5 4WT, UK.
Hayes J; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, Lancashire, PR1 2HE, UK.
Snape TJ; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, Lancashire, PR1 2HE, UK; Leicester School of Pharmacy, De Montfort University, Leicester, LE1 9BH, UK. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Dec 05; Vol. 225, pp. 113751. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article
MeSH Terms :
Amides/*pharmacology
Antineoplastic Agents/*pharmacology
Cerebellar Neoplasms/*drug therapy
Medulloblastoma/*drug therapy
Urea/*pharmacology
Amides/chemical synthesis ; Amides/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cerebellar Neoplasms/pathology ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Medulloblastoma/pathology ; Molecular Structure ; Structure-Activity Relationship ; Urea/analogs & derivatives ; Urea/chemistry
Czasopismo naukowe
Tytuł :
Higher blood urea nitrogen level is independently linked with the presence and severity of neonatal sepsis.
Autorzy :
Li X; Zhengzhou Key Laboratory of Children's Infection and Immunity, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Li T; Zhengzhou Key Laboratory of Children's Infection and Immunity, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Wang J; Department of Neonatology, Ordos Central Hospital, Ordos, China.
Dong G; Zhengzhou Key Laboratory of Children's Infection and Immunity, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Zhang M; Zhengzhou Key Laboratory of Children's Infection and Immunity, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Xu Z; Zhengzhou Key Laboratory of Children's Infection and Immunity, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Hu Y; Zhengzhou Key Laboratory of Children's Infection and Immunity, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Xie B; Zhengzhou Key Laboratory of Children's Infection and Immunity, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Yang J; Zhengzhou Key Laboratory of Children's Infection and Immunity, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Wang Y; The Engineering Research Center for New Drug Screening, Inner Mongolia Medical University, Hohhot, China.
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Źródło :
Annals of medicine [Ann Med] 2021 Dec; Vol. 53 (1), pp. 2192-2198.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Urea Nitrogen*
Biomarkers/*blood
Neonatal Sepsis/*diagnosis
C-Reactive Protein ; Female ; Humans ; Hyperbilirubinemia ; Infant, Newborn ; Male ; Neonatal Sepsis/blood ; Neonatal Sepsis/epidemiology ; Predictive Value of Tests ; Prognosis ; ROC Curve
Czasopismo naukowe
Tytuł :
Supraphysiological concentration of urea affects the functional competence of Holstein-Friesian (Bos taurus) sperm.
Autorzy :
Lavanya M; Reproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560 030, India; Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, 243 122, India.
Swathi D; Reproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560 030, India.
Archana SS; Reproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560 030, India.
Ramya L; Reproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560 030, India.
Ranjithkumaran R; Reproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560 030, India.
Krishnaswamy N; ICAR-Indian Veterinary Research Institute, Bengaluru, 560 024, India.
Singh SK; Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, 243 122, India.
Krishnappa B; Reproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560 030, India.
Rajendran D; Feed Resources and Informatics Laboratory, Animal Nutrition Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560 030, India.
Kumar H; Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, 243 122, India.
Selvaraju S; Reproductive Physiology Laboratory, Animal Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bengaluru, 560 030, India. Electronic address: .
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Źródło :
Theriogenology [Theriogenology] 2021 Dec; Vol. 176, pp. 104-114. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji :
Journal Article
MeSH Terms :
Sperm Motility*
Urea*
Acrosome ; Animals ; Cattle ; Cryopreservation/veterinary ; Male ; Semen ; Spermatozoa
Czasopismo naukowe
Tytuł :
Nickel phosphide on Ni foam as anode and peroxymonosulfate as the chemical oxidizer for effective direct urea fuel cell.
Autorzy :
Hao J; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Zhao S; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Mao R; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. Electronic address: .
Zhao X; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło :
Journal of environmental sciences (China) [J Environ Sci (China)] 2021 Dec; Vol. 110, pp. 84-91. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Nickel*
Urea*
Electrodes ; Humans ; Hydrogen Peroxide ; Peroxides
Czasopismo naukowe
Tytuł :
Development of light-degradable poly(urethane-urea) hydrogel films.
Autorzy :
Paula CTB; CEMMPRE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Pólo II, 3030-790 Coimbra, Portugal.
Pereira P; CEMMPRE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Pólo II, 3030-790 Coimbra, Portugal; IPN, Instituto Pedro Nunes, Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Rua Pedro Nunes, 3030-199 Coimbra, Portugal.
Coelho JFJ; CEMMPRE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Pólo II, 3030-790 Coimbra, Portugal.
Fonseca AC; CEMMPRE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Pólo II, 3030-790 Coimbra, Portugal.
Serra AC; CEMMPRE, Department of Chemical Engineering, University of Coimbra, Rua Sílvio Lima-Pólo II, 3030-790 Coimbra, Portugal. Electronic address: .
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Źródło :
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2021 Dec; Vol. 131, pp. 112520. Date of Electronic Publication: 2021 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Hydrogels*
Urea*
Methylgalactosides ; Polyethylene Glycols
Czasopismo naukowe
Tytuł :
Synthesis and Preclinical Evaluation of [ F]SiFA-PSMA Inhibitors in a Prostate Cancer Model.
Autorzy :
Bailey JJ; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta T6G 1Z2, Canada.
Wuest M; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta T6G 1Z2, Canada.
Wagner M; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta T6G 1Z2, Canada.
Bhardwaj A; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta T6G 1Z2, Canada.
Wängler C; Clinic of Radiology and Nuclear Medicine, Biomedical Chemistry and Clinic of Radiology and Nuclear Medicine, Molecular Imaging and Radiochemistry, Medical Faculty Mannheim of Heidelberg University, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.
Wängler B; Clinic of Radiology and Nuclear Medicine, Biomedical Chemistry and Clinic of Radiology and Nuclear Medicine, Molecular Imaging and Radiochemistry, Medical Faculty Mannheim of Heidelberg University, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.
Valliant JF; Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street, Hamilton, Ontario L8S 4K1, Canada.
Schirrmacher R; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta T6G 1Z2, Canada.
Wuest F; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta T6G 1Z2, Canada.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Nov 11; Vol. 64 (21), pp. 15671-15689. Date of Electronic Publication: 2021 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Positron-Emission Tomography*
Prostate-Specific Antigen/*antagonists & inhibitors
Prostatic Neoplasms/*diagnostic imaging
Radiopharmaceuticals/*pharmacology
Urea/*analogs & derivatives
Animals ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Fluorine Radioisotopes ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Molecular Structure ; Neoplasms, Experimental/diagnostic imaging ; Neoplasms, Experimental/metabolism ; Prostate-Specific Antigen/analysis ; Prostate-Specific Antigen/metabolism ; Prostatic Neoplasms/metabolism ; Radiopharmaceuticals/chemical synthesis ; Radiopharmaceuticals/chemistry ; Structure-Activity Relationship ; Urea/chemical synthesis ; Urea/chemistry ; Urea/pharmacology
Czasopismo naukowe

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