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Wyszukujesz frazę ""Urease"" wg kryterium: Temat


Tytuł :
Paper-based analytical device with colorimetric detection for urease activity determination in soils and evaluation of potential inhibitors.
Autorzy :
Tavares MC; Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, Campus A.C. Simões, 57072-900, Maceió, Alagoas, Brazil.
Oliveira KA; Instituto de Química, Universidade Federal de Goiás, Goiânia, GO 74690-900, Brazil.
de Fátima Â; Departmento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627, Pampulha, Belo Horizonte, MG 31270-901, Brazil.
Coltro WKT; Instituto de Química, Universidade Federal de Goiás, Goiânia, GO 74690-900, Brazil. Electronic address: .
Santos JCC; Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, Campus A.C. Simões, 57072-900, Maceió, Alagoas, Brazil. Electronic address: .
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Źródło :
Talanta [Talanta] 2021 Aug 01; Vol. 230, pp. 122301. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Soil*
Urease*
Colorimetry ; Fertilizers ; Nitrogen ; Urea
Czasopismo naukowe
Tytuł :
Proteus mirabilis Urease: Unsuspected Non-Enzymatic Properties Relevant to Pathogenicity.
Autorzy :
Grahl MVC; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BRAINS) and Graduate Program in Medicine and Health Sciences, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre CEP 90610-000, RS, Brazil.
Uberti AF; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BRAINS) and Graduate Program in Medicine and Health Sciences, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre CEP 90610-000, RS, Brazil.
Broll V; Graduate Program in Cellular and Molecular Biology, Center of Biotechnology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre CEP 91501-970, RS, Brazil.
Bacaicoa-Caruso P; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BRAINS) and Graduate Program in Cellular and Molecular Biology, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre CEP 90610-000, RS, Brazil.
Meirelles EF; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BRAINS), Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre CEP 90610-000, RS, Brazil.
Carlini CR; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BRAINS) and School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre CEP 90610-000, RS, Brazil.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 04; Vol. 22 (13). Date of Electronic Publication: 2021 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
Proteus mirabilis/*enzymology
Proteus mirabilis/*pathogenicity
Urease/*metabolism
Urease/*toxicity
Amino Acid Sequence ; Animals ; Calcium/metabolism ; Cell Line ; Cell Nucleus/metabolism ; HEK293 Cells ; Humans ; In Vitro Techniques ; Mice ; Microglia/drug effects ; Microglia/metabolism ; Microglia/microbiology ; Models, Molecular ; Neurons/drug effects ; Neurons/metabolism ; Neurons/microbiology ; Neurotoxins/chemistry ; Neurotoxins/metabolism ; Neurotoxins/toxicity ; Nuclear Localization Signals ; Platelet Aggregation/drug effects ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Recombinant Proteins/toxicity ; Urease/chemistry ; Virulence/physiology
Czasopismo naukowe
Tytuł :
Exploring biologically active hybrid pharmacophore N-substituted hydrazine-carbothioamides for urease inhibition: In vitro and in silico approach.
Autorzy :
Naseem S; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
Ashraf M; Institute of Chemistry, The Islamia University Bahawalpur, Bahawalpur 63100, Pakistan.
Khan S; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan; Department of Chemistry, The Women University, Multan 60000, Pakistan.
Rafiq M; School of Chemistry and Chemical Engineering, South China University of Technology, Guanzhou 510640, China.
Kashif M; Department of Chemistry, Emerson University Multan, Bosan Road, Multan, Pakistan.
Rahman J; Institute of Chemistry, The Islamia University Bahawalpur, Bahawalpur 63100, Pakistan.
Rauf MK; Department of Chemistry, Govt. Post-Graduate Gordon College Rawalpindi, Pakistan.
Halim SA; Natural and Medical Sciences Research Center, University of Nizwa, PO Box 33, 616 Birkat Al Mauz, Nizwa, Oman.
Uddin J; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.
Khan A; Natural and Medical Sciences Research Center, University of Nizwa, PO Box 33, 616 Birkat Al Mauz, Nizwa, Oman. Electronic address: .
Al-Harrasi A; Natural and Medical Sciences Research Center, University of Nizwa, PO Box 33, 616 Birkat Al Mauz, Nizwa, Oman. Electronic address: .
Shafiq Z; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 01; Vol. 182, pp. 534-544. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Quantitative Structure-Activity Relationship*
Enzyme Inhibitors/*chemistry
Hydrazines/*chemistry
Thioamides/*chemistry
Urease/*antagonists & inhibitors
Binding Sites ; Enzyme Inhibitors/pharmacology ; Hydrazines/pharmacology ; Molecular Docking Simulation ; Protein Binding ; Thioamides/pharmacology ; Urease/chemistry ; Urease/metabolism
Czasopismo naukowe
Tytuł :
Urease Inhibitory Kinetic Studies of Various Extracts and Pure Compounds from Cinnamomum Genus.
Autorzy :
Kumar M; Department of Biotechnology, Kurukshetra University, Kurukshetra 136119, India.
Sikri N; Department of Biotechnology, Kurukshetra University, Kurukshetra 136119, India.
Chahal S; Department of Biotechnology, Kurukshetra University, Kurukshetra 136119, India.
Sharma J; Department of Biotechnology, Kurukshetra University, Kurukshetra 136119, India.
Sharma B; Department of Biotechnology, Kurukshetra University, Kurukshetra 136119, India.
Yadav P; Department of Zoology, Maharshi Dayanand University, Rohtak 124001, India.
Bhardwaj M; Department of Zoology, Maharshi Dayanand University, Rohtak 124001, India.
Vashishth D; Department of Zoology, Maharshi Dayanand University, Rohtak 124001, India.
Kadyan P; Department of Zoology, Maharshi Dayanand University, Rohtak 124001, India.
Kataria SK; Department of Zoology, Maharshi Dayanand University, Rohtak 124001, India.
Dalal S; Department of Biotechnology, Kurukshetra University, Kurukshetra 136119, India.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 22; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 22.
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Proteins*/antagonists & inhibitors
Bacterial Proteins*/chemistry
Molecular Docking Simulation*
Urease*/antagonists & inhibitors
Urease*/chemistry
Cinnamomum/*chemistry
Enzyme Inhibitors/*chemistry
Plant Extracts/*chemistry
Czasopismo naukowe
Tytuł :
Urea-Urease Reaction in Controlling Properties of Supramolecular Hydrogels: Pros and Cons.
Autorzy :
Panja S; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK.
Adams DJ; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Jun 21; Vol. 27 (35), pp. 8928-8939. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Urea*
Urease*
Hydrogels ; Hydrogen-Ion Concentration ; Kinetics
Czasopismo naukowe
Tytuł :
NQS-Doped PDMS Solid Sensor: From Water Matrix to Urine Enzymatic Application.
Autorzy :
Martínez-Aviñó A; MINTOTA Research Group, Department of Analytical Chemistry, University of Valencia, Dr. Moliner 50, Burjassot, 46100 Valencia, Spain.
Hakobyan L; MINTOTA Research Group, Department of Analytical Chemistry, University of Valencia, Dr. Moliner 50, Burjassot, 46100 Valencia, Spain.
Ballester-Caudet A; MINTOTA Research Group, Department of Analytical Chemistry, University of Valencia, Dr. Moliner 50, Burjassot, 46100 Valencia, Spain.
Moliner-Martínez Y; MINTOTA Research Group, Department of Analytical Chemistry, University of Valencia, Dr. Moliner 50, Burjassot, 46100 Valencia, Spain.
Molins-Legua C; MINTOTA Research Group, Department of Analytical Chemistry, University of Valencia, Dr. Moliner 50, Burjassot, 46100 Valencia, Spain.
Campíns-Falcó P; MINTOTA Research Group, Department of Analytical Chemistry, University of Valencia, Dr. Moliner 50, Burjassot, 46100 Valencia, Spain.
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Źródło :
Biosensors [Biosensors (Basel)] 2021 Jun 08; Vol. 11 (6). Date of Electronic Publication: 2021 Jun 08.
Typ publikacji :
Journal Article
MeSH Terms :
Naphthoquinones/*chemistry
Urea/*metabolism
Urease/*metabolism
Colorimetry ; Dimethylpolysiloxanes ; Polymers ; Urease/analysis ; Water/chemistry
Czasopismo naukowe
Tytuł :
Zerumbone Inhibits Helicobacter pylori Urease Activity.
Autorzy :
Woo HJ; Department of Clinical Laboratory Science, Semyung University, Jecheon 27136, Korea.
Yang JY; Division of Crop Foundation, National Institute of Crop Science (NICS), Rural Development Administration (RDA), Wanju 55365, Korea.
Lee P; School of Oriental Medicine and Bio Convergence Sciences, Semyung University, Jecheon 27136, Korea.
Kim JB; Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University, Wonju 26493, Korea.
Kim SH; Department of Clinical Laboratory Science, Semyung University, Jecheon 27136, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 May 01; Vol. 26 (9). Date of Electronic Publication: 2021 May 01.
Typ publikacji :
Journal Article
MeSH Terms :
Helicobacter pylori/*drug effects
Sesquiterpenes/*pharmacology
Urease/*antagonists & inhibitors
Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents/pharmacology ; Dimerization ; Microbial Sensitivity Tests ; Protein Domains ; Reproducibility of Results ; Urease/metabolism
Czasopismo naukowe
Tytuł :
Synthesis, X-ray, Hirshfeld surface analysis, exploration of DNA binding, urease enzyme inhibition and anticancer activities of novel adamantane-naphthyl thiourea conjugate.
Autorzy :
Arshad N; Department of Chemistry, Allama Iqbal Open University, 44000 Islamabad, Pakistan. Electronic address: .
Saeed A; Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan. Electronic address: .
Perveen F; Research Center for Modeling and Simulations, National University of Sciences and Technology (NUST), Islamabad, Pakistan.
Ujan R; M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro 76080, Pakistan.
Farooqi SI; Department of Chemistry, Allama Iqbal Open University, 44000 Islamabad, Pakistan.
Ali Channar P; Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan.
Shabir G; Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan.
El-Seedi HR; Pharmacognosy Group, Department of Medicinal Chemistry, Biomedical Center (BMC), Uppsala University, Uppsala, Sweden.
Javed A; Healthcare Biotechnology, Atta-ur-Rehman School of Applied Biosciences, National University of Science and Technology (NUST), Islamabad, Pakistan.
Yamin M; Healthcare Biotechnology, Atta-ur-Rehman School of Applied Biosciences, National University of Science and Technology (NUST), Islamabad, Pakistan.
Bolte M; Institut für Anorganische Chemie, J.W.-Goethe-Universität, Max-von-Laue-Str.7, D-60438 Frankfurt/Main, Germany.
Hökelek T; Hacettepe University, Department of Physics, 06800 Beytepe-Ankara, Turkey.
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2021 Apr; Vol. 109, pp. 104707. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article
MeSH Terms :
Adamantane/*chemistry
Antineoplastic Agents/*chemistry
Antineoplastic Agents/*pharmacology
Thiourea/*analogs & derivatives
Urease/*metabolism
Adamantane/chemical synthesis ; Adamantane/pharmacology ; Antineoplastic Agents/chemical synthesis ; Cell Line, Tumor ; Cell Survival ; Crystallography, X-Ray ; DNA/chemistry ; Gene Expression Regulation, Enzymologic/drug effects ; Humans ; Models, Molecular ; Molecular Docking Simulation ; Molecular Structure ; Thiourea/chemical synthesis ; Thiourea/chemistry ; Thiourea/pharmacology ; Urease/genetics
Czasopismo naukowe
Tytuł :
Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies.
Autorzy :
Mazzei L; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.; Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Giuseppe Fanin 40, 40127, Bologna, Italy.
Contaldo U; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.; Laboratory of Chemistry and Biology of Metals, Université Grenoble Alpes, CEA, CNRS, 17 Avenue des Martyrs, 38000, Grenoble, France.
Musiani F; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.; Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Giuseppe Fanin 40, 40127, Bologna, Italy.
Cianci M; Department of Agricultural, Food and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131, Ancona, Italy.
Bagnolini G; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.
Roberti M; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.
Ciurli S; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.; Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Giuseppe Fanin 40, 40127, Bologna, Italy.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Mar 08; Vol. 60 (11), pp. 6029-6035. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article
MeSH Terms :
Density Functional Theory*
Catechols/*pharmacology
Enzyme Inhibitors/*pharmacology
Sulfhydryl Compounds/*pharmacology
Urease/*antagonists & inhibitors
Catechols/chemistry ; Crystallography, X-Ray ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Kinetics ; Models, Molecular ; Molecular Structure ; Sporosarcina/enzymology ; Sulfhydryl Compounds/chemistry ; Urease/metabolism
SCR Organism :
Sporosarcina pasteurii
Czasopismo naukowe
Tytuł :
Neurotoxic and convulsant effects induced by jack bean ureases on the mammalian nervous system.
Autorzy :
Almeida CGM; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Graduate Program in Medicine and Health Sciences, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Costa-Higuchi K; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Graduate Program in Materials Technology and Engineering, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Piovesan AR; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Graduate Program in Celular and Molecular Biology, Center of Biotechnology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Moro CF; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Graduate Program in Medicine and Health Sciences, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Venturin GT; Preclinical Research Center, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Greggio S; Preclinical Research Center, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Costa-Ferro ZS; Laboratory of Neuroscience, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Salamoni SD; Laboratory of Neuroscience, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Peigneur S; Laboratory of Toxicology & Pharmacology, University of Leuven (KU Leuven), Leuven, Belgium.
Tytgat J; Laboratory of Toxicology & Pharmacology, University of Leuven (KU Leuven), Leuven, Belgium.
de Lima ME; Institute of Teaching and Research, Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil.
Silva CND; Faculty of Pharmacy, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Vinadé L; Laboratory of Neurobiology and Toxinology (Lanetox), Universidade Federal do Pampa, São Gabriel, RS, Brazil.
Rowan EG; Strathclyde Institute for Biomedical Sciences, University of Strathclyde, Glasgow, UK.
DaCosta JC; Laboratory of Neuroscience, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Dal Belo CA; Laboratory of Neurobiology and Toxinology (Lanetox), Universidade Federal do Pampa, São Gabriel, RS, Brazil. Electronic address: .
Carlini CR; Laboratory of Neurotoxins, Brain Institute of Rio Grande do Sul (BraIns), Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Graduate Program in Medicine and Health Sciences, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Scholl of Medicine, Pontificía Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2021 Apr 30; Vol. 454, pp. 152737. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Canavalia/*chemistry
Neurotoxicity Syndromes/*etiology
Plant Proteins/*toxicity
Toxins, Biological/*toxicity
Urease/*toxicity
Animals ; Convulsants/isolation & purification ; Convulsants/toxicity ; Female ; Male ; Mice ; Nervous System/drug effects ; Nervous System/pathology ; Neurotoxicity Syndromes/physiopathology ; Plant Proteins/isolation & purification ; Rats ; Rats, Wistar ; Toxins, Biological/isolation & purification ; Urease/isolation & purification ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Drug-Free Enzyme-Based Bactericidal Nanomotors against Pathogenic Bacteria.
Autorzy :
Vilela D; Smart nano-bio-devices, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.
Blanco-Cabra N; Bacterial infections: antimicrobial therapies, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.
Eguskiza A; Smart nano-bio-devices, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.
Hortelao AC; Smart nano-bio-devices, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.
Torrents E; Bacterial infections: antimicrobial therapies, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.; Microbiology Section, Department of Genetics, Microbiology and Statistics Faculty of Biology, University of Barcelona, 643 Diagonal Ave., 08028 Barcelona, Spain.
Sanchez S; Smart nano-bio-devices, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028 Barcelona Spain.; Institució Catalana de Recerca i Estudis Avancats (ICREA), Pg. Lluís Companys 23, 08010 Barcelona, Spain.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Apr 07; Vol. 13 (13), pp. 14964-14973. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Escherichia coli/*drug effects
Muramidase/*pharmacology
Nanoparticles/*chemistry
Silicon Dioxide/*chemistry
Urease/*pharmacology
Anti-Bacterial Agents/administration & dosage ; Biocatalysis ; Biofilms/drug effects ; Canavalia/enzymology ; Drug Carriers/chemistry ; Escherichia coli/physiology ; Escherichia coli Infections/drug therapy ; Humans ; Muramidase/administration & dosage ; Urease/administration & dosage ; Urinary Tract Infections/drug therapy
Czasopismo naukowe
Tytuł :
Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors.
Autorzy :
Rashid M; Department of Chemistry, Allama Iqbal Open University, Islamabad 44000, Pakistan.
Rafique H; Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.
Roshan S; Department of Zoology, University of Gujrat, Gujrat 50700, Pakistan.
Shamas S; Department of Zoology, University of Gujrat, Gujrat 50700, Pakistan.
Iqbal Z; Department of Chemistry, Allama Iqbal Open University, Islamabad 44000, Pakistan.
Ashraf Z; Department of Chemistry, Allama Iqbal Open University, Islamabad 44000, Pakistan.
Abbas Q; Department of Physiology, University of Sindh, Jamshoro, Pakistan.
Hassan M; Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.
Qureshi ZUR; Department of Pharmacy, SBK Women University, Quetta, Balochistan, Pakistan.
Asad MHHB; Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Pakistan.; Institute of Fundamental Medicine, Department of Genetics, Kazan Federal University, Russia.
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Źródło :
BioMed research international [Biomed Res Int] 2020 Dec 24; Vol. 2020, pp. 8867407. Date of Electronic Publication: 2020 Dec 24 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Benzoates*/chemistry
Benzoates*/metabolism
Benzoates*/pharmacology
Enzyme Inhibitors*/chemistry
Enzyme Inhibitors*/metabolism
Enzyme Inhibitors*/pharmacology
Canavalia/*enzymology
Plant Proteins/*antagonists & inhibitors
Urease/*antagonists & inhibitors
Amides/chemistry ; Amides/metabolism ; Binding Sites ; Esters/chemistry ; Esters/metabolism ; Hydrolysis ; Kinetics ; Molecular Docking Simulation ; Plant Proteins/chemistry ; Plant Proteins/metabolism ; Urea/metabolism ; Urease/chemistry ; Urease/metabolism
Czasopismo naukowe
Tytuł :
N -monoarylacetothioureas as potent urease inhibitors: synthesis, SAR, and biological evaluation.
Autorzy :
Li WY; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Ni WW; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Ye YX; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, PR China.
Fang HL; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Pan XM; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
He JL; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Zhou TL; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Yi J; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Liu SS; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Zhou M; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Xiao ZP; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, PR China.
Zhu HL; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, PR China.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 404-413.
Typ publikacji :
Journal Article
MeSH Terms :
Helicobacter pylori/*drug effects
Urea/*pharmacology
Urease/*antagonists & inhibitors
Anti-Bacterial Agents ; Dose-Response Relationship, Drug ; Enzyme Inhibitors ; Helicobacter pylori/cytology ; Helicobacter pylori/enzymology ; Microbial Sensitivity Tests ; Molecular Structure ; Structure-Activity Relationship ; Urea/analogs & derivatives ; Urea/chemistry ; Urease/metabolism
Czasopismo naukowe
Tytuł :
Flavonoid analogues as urease inhibitors: Synthesis, biological evaluation, molecular docking studies and in-silico ADME evaluation.
Autorzy :
Liu H; Medical College, Guangxi University, Nanning 530004, China; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
Wang Y; College of Life Science and Technology, Guangxi University, Nanning 530004, China.
Lv M; Medical College, Guangxi University, Nanning 530004, China.
Luo Y; Guangxi Institute for Food and Drug Control, Nanning 530021, China.
Liu BM; Guangxi Key Laboratory of Traditional Chinese Medicine, Quality Standards, Nanning 530022, China.
Huang Y; Guangxi Key Laboratory of Traditional Chinese Medicine, Quality Standards, Nanning 530022, China.
Wang M; College of Life Science and Technology, Guangxi University, Nanning 530004, China. Electronic address: .
Wang J; Medical College, Guangxi University, Nanning 530004, China; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2020 Dec; Vol. 105, pp. 104370. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Docking Simulation*
Enzyme Inhibitors/*pharmacology
Flavonoids/*pharmacology
Urease/*antagonists & inhibitors
Canavalia/enzymology ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Flavonoids/chemical synthesis ; Flavonoids/chemistry ; Molecular Structure ; Structure-Activity Relationship ; Urease/metabolism
Czasopismo naukowe
Tytuł :
Novel thiobarbiturates as potent urease inhibitors with potential antibacterial activity: Design, synthesis, radiolabeling and biodistribution study.
Autorzy :
Abdulwahab HG; Pharmaceutical Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt. Electronic address: .
Harras MF; Pharmaceutical Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
El Menofy NG; Department of Microbiology and Immunology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Hegab AM; Developmental Pharmacology Department, National Organization for Drug Control and Research, Giza, Egypt.
Essa BM; Radioactive Isotopes and Generator Department, Hot Laboratories Center, Egyptian Atomic Energy Authority (EAEA), P.O. Box 13759, Cairo, Egypt.
Selim AA; Labeled Compounds Department, Hot Labs Center, Egyptian Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt.
Sakr TM; Radioactive Isotopes and Generator Department, Hot Laboratories Center, Egyptian Atomic Energy Authority (EAEA), P.O. Box 13759, Cairo, Egypt.
El-Zahabi HSA; Pharmaceutical Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
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Źródło :
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Dec 01; Vol. 28 (23), pp. 115759. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Anti-Bacterial Agents/*chemical synthesis
Enzyme Inhibitors/*chemistry
Thiobarbiturates/*chemistry
Urease/*antagonists & inhibitors
Animals ; Anti-Bacterial Agents/metabolism ; Anti-Bacterial Agents/pharmacology ; Binding Sites ; Catalytic Domain ; Enzyme Inhibitors/metabolism ; Enzyme Inhibitors/pharmacology ; Hydrogen-Ion Concentration ; Isotope Labeling ; Klebsiella pneumoniae/drug effects ; Male ; Mice ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Organotechnetium Compounds/chemistry ; Proteus vulgaris/drug effects ; Structure-Activity Relationship ; Thiobarbiturates/metabolism ; Thiobarbiturates/pharmacology ; Thiourea/analogs & derivatives ; Thiourea/metabolism ; Thiourea/pharmacology ; Tissue Distribution ; Urease/metabolism
Czasopismo naukowe
Tytuł :
4-Oxycoumarinyl linked acetohydrazide Schiff bases as potent urease inhibitors.
Autorzy :
Naz F; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Kanwal; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Latif M; Bahria University Medical and Dental College, Karachi 75270, Pakistan.
Salar U; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Khan KM; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 31441, Dammam, Saudi Arabia. Electronic address: .
Al-Rashida M; Department of Chemistry, Forman Christian College (A Chartered University), Ferozepur Road, Lahore 54600, Pakistan.
Ali I; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Ali B; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Taha M; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 31441, Dammam, Saudi Arabia.
Perveen S; PCSIR Laboratories Complex, Karachi, Shahrah-e-Dr. Salimuzzaman Siddiqui, Karachi 75280, Pakistan.
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2020 Dec; Vol. 105, pp. 104365. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coumarins/*pharmacology
Enzyme Inhibitors/*pharmacology
Hydrazines/*pharmacology
Urease/*antagonists & inhibitors
Coumarins/chemistry ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Humans ; Hydrazines/chemical synthesis ; Hydrazines/chemistry ; Molecular Docking Simulation ; Molecular Structure ; Schiff Bases/chemical synthesis ; Schiff Bases/chemistry ; Schiff Bases/pharmacology ; Structure-Activity Relationship ; Urease/metabolism
Czasopismo naukowe
Tytuł :
'Urease immobilized single-kit' for sensing of thiourea-glucose pair employing fluorescence 'Turn off - Turn on' and as an efficient sorbent for selective sample cleanup of thiourea.
Autorzy :
Mondal S; Analytical Laboratory, Department of Chemistry, Visva-Bharati, Santiniketan, 731235, India.
Saha S; Analytical Laboratory, Department of Chemistry, Visva-Bharati, Santiniketan, 731235, India.
Mishra S; Analytical Laboratory, Department of Chemistry, Visva-Bharati, Santiniketan, 731235, India.
Sarkar R; Analytical Laboratory, Department of Chemistry, Visva-Bharati, Santiniketan, 731235, India.
Roy D; Analytical Laboratory, Department of Chemistry, Visva-Bharati, Santiniketan, 731235, India.
Mandal B; Analytical Laboratory, Department of Chemistry, Visva-Bharati, Santiniketan, 731235, India. Electronic address: .
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Źródło :
Analytica chimica acta [Anal Chim Acta] 2021 Jan 02; Vol. 1141, pp. 180-193. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article
MeSH Terms :
Thiourea*
Urease*
Fluorescence ; Glucose ; Hydrogen-Ion Concentration
Czasopismo naukowe
Tytuł :
Use of a urease inhibitor to mitigate ammonia emissions from urine patches.
Autorzy :
Rodriguez MJ; Institute of Agriculture and Environment, Massey University, Palmerston North, New Zealand.
Saggar S; Ecosystems & Global Change, Landcare Research, Palmerston North, New Zealand.
Berben P; Ecosystems & Global Change, Landcare Research, Palmerston North, New Zealand.
Palmada T; Ecosystems & Global Change, Landcare Research, Palmerston North, New Zealand.
Lopez-Villalobos N; Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand.
Pal P; Ecosystems & Global Change, Landcare Research, Palmerston North, New Zealand.
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Źródło :
Environmental technology [Environ Technol] 2021 Jan; Vol. 42 (1), pp. 20-31. Date of Electronic Publication: 2019 Jun 09.
Typ publikacji :
Journal Article
MeSH Terms :
Ammonia*/analysis
Urease*
Animals ; Fertilizers/analysis ; Soil ; Urea
Czasopismo naukowe
Tytuł :
Structure-Function Insights of Jaburetox and Soyuretox: Novel Intrinsically Disordered Polypeptides Derived from Plant Ureases.
Autorzy :
Grahl MVC; Graduate Program in Medicine and Health Sciences, Brain Institute of Rio Grande do Sul (InsCer), Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre CEP 90610-000, Brazil.
Lopes FC; Graduate Program in Cellular and Molecular Biology, Center of Biotechnology, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Gonçalves 9500, Building 43431, Porto Alegre CEP 91501-970, RS, Brazil.
Martinelli AHS; Department of Biophysics & Deparment of Molecular Biology and Biotechnology-Biosciences Institute (IB), Universidade Federal do Rio Grande do Sul, UFRGS, Porto Alegre 91501-970, RS, Brazil.
Carlini CR; Graduate Program in Medicine and Health Sciences, Brain Institute of Rio Grande do Sul (InsCer), Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre CEP 90610-000, Brazil.; Brain Institute and School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre 90610-000, RS, Brazil.
Fruttero LL; Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba CP 5000, Argentina.; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba CP 5000, Argentina.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Nov 16; Vol. 25 (22). Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Intrinsically Disordered Proteins/*chemistry
Intrinsically Disordered Proteins/*metabolism
Peptides/*chemistry
Peptides/*metabolism
Plant Proteins/*chemistry
Plant Proteins/*metabolism
Urease/*metabolism
Amino Acid Sequence ; Pesticides/toxicity ; Structure-Activity Relationship ; Urease/chemistry
Czasopismo naukowe

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