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Tytuł:
Genetic fusion of CCL11 to antigens enhances antigenicity in nucleic acid vaccines and eradicates tumor mass through optimizing T-cell response.
Autorzy:
Qi H; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science, Beijing, China. .; Newish Biological R&D Center, Wuxi, China. .
Sun Z; State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, 300071, China.; Newish Biological R&D Center, Wuxi, China.
Gao T; Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Yao Y; Newish Biological R&D Center, Wuxi, China.
Wang Y; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science, Beijing, China.; Newish Biological R&D Center, Wuxi, China.
Li W; Newish Biological R&D Center, Wuxi, China.
Wang X; Newish Biological R&D Center, Wuxi, China.
Wang X; Newish Biological R&D Center, Wuxi, China.
Liu D; Newish Biological R&D Center, Wuxi, China.
Jiang JD; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science, Beijing, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2024 Mar 08; Vol. 23 (1), pp. 46. Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Vaccines, DNA*/genetics
Papillomavirus Vaccines*/genetics
Neoplasms*/genetics
Neoplasms*/therapy
Oncogene Proteins, Viral*/genetics
Cancer Vaccines*
Animals ; Mice ; Nucleic Acid-Based Vaccines ; CD8-Positive T-Lymphocytes ; Papillomavirus E7 Proteins/genetics ; Mice, Inbred C57BL ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Prophylactic cancer vaccines: development and challenges for HBV and HPV vaccines in Latin America.
Autorzy:
Ramírez-López LX; Facultad Ciencias de la Salud, Universidad de Boyacá. Tunja, Colombia. Doctorado en Salud Pública, Escuela de Salud Pública de México. Cuernavaca, Morelos, Mexico.. .
Carnalla-Cortés M; Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública. Cuernavaca, Morelos, Mexico.. .
Barrientos-Gutiérrez T; Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública. Cuernavaca, Morelos, Mexico.. .
Coursaget P; Faculté des Sciences Pharmaceutiques, Université F Rabelais. Tours, France.. .
Muñoz N; Independent consultant. Lyon, France.. .
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Źródło:
Salud publica de Mexico [Salud Publica Mex] 2023 Dec 08; Vol. 66 (1, ene-feb), pp. 95-103. Date of Electronic Publication: 2023 Dec 08.
Typ publikacji:
Journal Article
MeSH Terms:
Papillomavirus Vaccines*
Cancer Vaccines*
Papillomavirus Infections*/epidemiology
Papillomavirus Infections*/prevention & control
Uterine Cervical Neoplasms*/epidemiology
Uterine Cervical Neoplasms*/prevention & control
Female ; Humans ; Child ; Hepatitis B virus ; Latin America/epidemiology ; Vaccination ; Hepatitis B Vaccines
Czasopismo naukowe
Tytuł:
A novel SARS-CoV-2 Beta RBD DNA vaccine directly targeted to antigen-presenting cells induces strong humoral and T cell responses.
Autorzy:
Kuczkowska K; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway. .
Bjerkan L; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Stubsrud E; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Husbyn HC; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Chellappa S; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.; Veterinærinstituttet, Elizabeth Stephansens Vei 1, 1433, Ås, Norway.
Hauge A; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Skarshaug R; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Torgersen ML; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Heim JB; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Jørgensen MJ; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Wold CW; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Schleimann MH; Department of Clinical Medicine/Infectious Diseases, Aarhus University, Palle Juul-Jensens Boulevard 45, 8200, Aarhus N, Denmark.
Tolstrup M; Department of Clinical Medicine/Infectious Diseases, Aarhus University, Palle Juul-Jensens Boulevard 45, 8200, Aarhus N, Denmark.
Granum S; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Fredriksen AB; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Pedersen MW; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
Norheim G; Nykode Therapeutics AS, Oslo Research Park, Gaustadalléen 21, 0349, Oslo, Norway.
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 02; Vol. 13 (1), pp. 18902. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Vaccines, DNA*
COVID-19*/prevention & control
Cancer Vaccines*
Animals ; Humans ; Mice ; COVID-19 Vaccines ; SARS-CoV-2 ; Pandemics ; T-Lymphocytes ; Antigen-Presenting Cells ; Broadly Neutralizing Antibodies ; DNA ; Immunoglobulin G ; Antibodies, Neutralizing ; Antibodies, Viral
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
mRNA-based precision targeting of neoantigens and tumor-associated antigens in malignant brain tumors.
Autorzy:
Trivedi V; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Yang C; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Klippel K; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Yegorov O; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
von Roemeling C; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Hoang-Minh L; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Fenton G; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Ogando-Rivas E; Boston Medical Center, Boston, MA, USA.
Castillo P; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Moore G; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Long-James K; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Dyson K; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Doonan B; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Flores C; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA.
Mitchell DA; University of Florida, 1333 Center Drive, BSB B1-118, Gainesville, FL, 32610, USA. .
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Źródło:
Genome medicine [Genome Med] 2024 Jan 25; Vol. 16 (1), pp. 17. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Neoplasms*/genetics
Brain Neoplasms*/therapy
Medulloblastoma*
Cancer Vaccines*/genetics
Cerebellar Neoplasms*
Humans ; Animals ; Mice ; mRNA Vaccines ; Antigens, Neoplasm/genetics ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł:
Immunoinformatics Approach to Design a Chimeric CD70-Peptide Vaccine against Renal Cell Carcinoma.
Autorzy:
Namdari H; Iranian Tissue Bank and Research Center, Tehran University of Medical Science, Tehran, Iran.
Rezaei F; Virology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Heidarnejad F; Biotechnology Research Center (BRC), Pasteur Institute of Iran, Tehran, Iran.
Yaghoubzad-Maleki M; Division of Biochemistry, Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Karamigolbaghi M; Iranian Tissue Bank and Research Center, Tehran University of Medical Science, Tehran, Iran.
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Źródło:
Journal of immunology research [J Immunol Res] 2024 Jan 27; Vol. 2024, pp. 2875635. Date of Electronic Publication: 2024 Jan 27 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/therapy
Kidney Neoplasms*/therapy
Cancer Vaccines*
Humans ; CD27 Ligand/genetics ; Computational Biology/methods ; Epitopes, B-Lymphocyte ; Epitopes, T-Lymphocyte ; Immunoinformatics ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Protein Subunit Vaccines ; Receptors, Tumor Necrosis Factor
Czasopismo naukowe
Tytuł:
mRNA vaccine in cancer therapy: Current advance and future outlook.
Autorzy:
Li Y; Department of Breast Surgery, Baoji Municipal Central Hospital, Weibin District, Baoji, Shaanxi, China.
Wang M; Graduate School, Beijing University of Chinese Medicine, Beijing, China.; Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, Beijing, China.
Peng X; Department of General Surgery, The Fourth Affiliated Hospital, China Medical University, Shenyang, China.
Yang Y; Clinical Research Center, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Chen Q; Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Liu J; Department of General Surgery, The Fourth Affiliated Hospital, China Medical University, Shenyang, China.
She Q; Department of Breast Surgery, Baoji Municipal Central Hospital, Weibin District, Baoji, Shaanxi, China.
Tan J; Department of Breast Surgery, Baoji Municipal Central Hospital, Weibin District, Baoji, Shaanxi, China.
Lou C; Department of Ophthalmology, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an, Shaanxi, China.
Liao Z; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.; Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, Sweden.
Li X; Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet, Biomedicum, Stockholm, Sweden.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Aug; Vol. 13 (8), pp. e1384.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Cancer Vaccines*/genetics
Cancer Vaccines*/therapeutic use
COVID-19*/prevention & control
Neoplasms*/therapy
Humans ; RNA, Viral ; SARS-CoV-2/genetics ; COVID-19 Vaccines/therapeutic use ; mRNA Vaccines
Czasopismo naukowe
Tytuł:
Efficacy of a synthetic peptide Chlamydia pecorum major outer membrane protein vaccine in a wild koala (Phascolarctos cinereus) population.
Autorzy:
Simpson SJ; Sydney School of Veterinary Science, The University of Sydney, Sydney, NSW, 2006, Australia. .
Higgins DP; Sydney School of Veterinary Science, The University of Sydney, Sydney, NSW, 2006, Australia.
Timms P; Centre for Bioinnovation, University of the Sunshine Coast, Sippy Downs, QLD, 4556, Australia.
Mella VSA; Sydney School of Veterinary Science, The University of Sydney, Sydney, NSW, 2006, Australia.
Crowther MS; School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, 2006, Australia.
Fernandez CM; Sydney School of Veterinary Science, The University of Sydney, Sydney, NSW, 2006, Australia.
McArthur C; School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW, 2006, Australia.
Phillips S; Centre for Bioinnovation, University of the Sunshine Coast, Sippy Downs, QLD, 4556, Australia.
Krockenberger MB; Sydney School of Veterinary Science, The University of Sydney, Sydney, NSW, 2006, Australia.
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 12; Vol. 13 (1), pp. 15087. Date of Electronic Publication: 2023 Sep 12.
Typ publikacji:
Journal Article; Randomized Controlled Trial, Veterinary; Research Support, Non-U.S. Gov't
MeSH Terms:
Cancer Vaccines*
Phascolarctidae*
Psittacosis*
Animals ; Australia ; Membrane Proteins ; Peptides ; Vaccines, Subunit ; Vaccines, Synthetic
SCR Organism:
Chlamydia pecorum
Czasopismo naukowe
Tytuł:
Preimmunization with Listeria-vectored cervical cancer vaccine candidate strains can establish specific T-cell immune memory and prevent tumorigenesis.
Autorzy:
Zhang Y; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Shen Zhen Biomed Alliance Biotech Group Co., Ltd., Shenzhen, China.
Liu S; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Chen M; Shen Zhen Biomed Alliance Biotech Group Co., Ltd., Shenzhen, China.
Ou Q; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Tian S; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Tang J; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
He Z; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Chen Z; Shen Zhen Biomed Alliance Biotech Group Co., Ltd., Shenzhen, China. .
Wang C; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Mar 04; Vol. 24 (1), pp. 288. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Cancer Vaccines*
Papillomavirus Infections*/complications
Papillomavirus Infections*/prevention & control
Uterine Cervical Neoplasms*/prevention & control
Listeria*
Papillomavirus Vaccines*
Humans ; Animals ; Mice ; Female ; Immunologic Memory ; Memory T Cells ; Carcinogenesis ; Cell Transformation, Neoplastic ; Antigens, Neoplasm
Czasopismo naukowe
Tytuł:
The XCL1-Mediated DNA Vaccine Targeting Type 1 Conventional Dendritic Cells Combined with Gemcitabine and Anti-PD1 Antibody Induces Potent Antitumor Immunity in a Mouse Lung Cancer Model.
Autorzy:
Zhang K; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Wuri Q; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Cai Z; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Qu X; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Zhang S; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Wu H; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Wu J; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Wang C; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
Yu X; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.; Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Kong W; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.; Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China.
Zhang H; National Engineering Laboratory for AIDS Vaccine, School of Life Science, Jilin University, Changchun 130012, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 04; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 04.
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms*/therapy
Vaccines, DNA*/immunology
Vaccines, DNA*/therapeutic use
Cancer Vaccines*/immunology
Cancer Vaccines*/therapeutic use
Animals ; Female ; Mice ; CD8-Positive T-Lymphocytes ; Dendritic Cells ; Gemcitabine ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
GV1001 Inhibits the Severity of the Ligature-Induced Periodontitis and the Vascular Lipid Deposition Associated with the Periodontitis in Mice.
Autorzy:
Kim SY; The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, 714 Tiverton Ave, Los Angeles, CA 90095, USA.
Kim YJ; Department of Periodontology, Seoul National University Gwanak Dental Hospital, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Kim S; The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, 714 Tiverton Ave, Los Angeles, CA 90095, USA.
Momeni M; The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, 714 Tiverton Ave, Los Angeles, CA 90095, USA.
Lee A; The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, 714 Tiverton Ave, Los Angeles, CA 90095, USA.
Treanor A; The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, 714 Tiverton Ave, Los Angeles, CA 90095, USA.
Kim S; Teloid Inc., 920 Westholme Avenue, Los Angeles, CA 90024, USA.
Kim RH; The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, 714 Tiverton Ave, Los Angeles, CA 90095, USA.; UCLA Jonsson Comprehensive Cancer Center, 10833 Le Conte Ave, Los Angeles, CA 90095, USA.
Park NH; The Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, 714 Tiverton Ave, Los Angeles, CA 90095, USA.; UCLA Jonsson Comprehensive Cancer Center, 10833 Le Conte Ave, Los Angeles, CA 90095, USA.; Department of Medicine, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 08; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 08.
Typ publikacji:
Journal Article
MeSH Terms:
Periodontitis*
Cancer Vaccines*
Atherosclerosis*
Humans ; Animals ; Mice ; Endothelial Cells ; Arteries ; Inflammation ; Vaccines, Subunit
Czasopismo naukowe
Tytuł:
Lack of shared neoantigens in prevalent mutations in cancer.
Autorzy:
Ragone C; Lab of Innovative Immunological Models Unit, Istituto Nazionale Tumori, IRCCS - 'Fondazione Pascale', Via Mariano Semmola, 52, 80131, Naples, Italy.
Cavalluzzo B; Lab of Innovative Immunological Models Unit, Istituto Nazionale Tumori, IRCCS - 'Fondazione Pascale', Via Mariano Semmola, 52, 80131, Naples, Italy.
Mauriello A; Lab of Innovative Immunological Models Unit, Istituto Nazionale Tumori, IRCCS - 'Fondazione Pascale', Via Mariano Semmola, 52, 80131, Naples, Italy.
Tagliamonte M; Lab of Innovative Immunological Models Unit, Istituto Nazionale Tumori, IRCCS - 'Fondazione Pascale', Via Mariano Semmola, 52, 80131, Naples, Italy. .
Buonaguro L; Lab of Innovative Immunological Models Unit, Istituto Nazionale Tumori, IRCCS - 'Fondazione Pascale', Via Mariano Semmola, 52, 80131, Naples, Italy. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Apr 10; Vol. 22 (1), pp. 344. Date of Electronic Publication: 2024 Apr 10.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/genetics
Neoplasms*/therapy
Cancer Vaccines*/genetics
Humans ; Antigens, Neoplasm/genetics ; Mutation/genetics ; Cell Cycle Checkpoints ; Immunotherapy ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Nanomaterial Delivery Vehicles for the Development of Neoantigen Tumor Vaccines for Personalized Treatment.
Autorzy:
Huang X; School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Zhu X; School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Yang H; School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Li Q; School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Gai L; College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, and Key Laboratory of Organosilicon Material Technology of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Sui X; School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Lu H; College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, and Key Laboratory of Organosilicon Material Technology of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Feng J; School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 25; Vol. 29 (7). Date of Electronic Publication: 2024 Mar 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cancer Vaccines*/therapeutic use
Nanostructures*/therapeutic use
Nucleic Acids*
Neoplasms*/therapy
Humans ; Precision Medicine
Czasopismo naukowe
Tytuł:
Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine.
Autorzy:
Valega-Mackenzie W; Office of Biostatistics and Pharmacovigilance, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America.
Rodriguez Messan M; Office of Biostatistics and Pharmacovigilance, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America.
Yogurtcu ON; Office of Biostatistics and Pharmacovigilance, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America.
Nukala U; Office of Biostatistics and Pharmacovigilance, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America.
Sauna ZE; Office of Therapeutic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America.
Yang H; Office of Biostatistics and Pharmacovigilance, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2024 Mar 01; Vol. 20 (3), pp. e1011247. Date of Electronic Publication: 2024 Mar 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Melanoma*/genetics
Cancer Vaccines*/genetics
Humans ; Antigens, Neoplasm/genetics ; Adjuvants, Immunologic ; Peptides
Czasopismo naukowe
Tytuł:
The quest for nanoparticle-powered vaccines in cancer immunotherapy.
Autorzy:
Sun Z; Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Zhao H; Department of Endodontics, East Branch of Jinan Stomatological Hospital, Jinan, 250000, Shandong, China.
Ma L; Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Shi Y; Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Ji M; Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Sun X; Department of Endodontics, Gaoxin Branch of Jinan Stomatological Hospital, Jinan, 250000, Shandong, China.
Ma D; Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Zhou W; Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Huang T; Department of Biomedical Engineering, Graeme Clark Institute, The University of Melbourne, Parkville, VIC, 3010, Australia. .
Zhang D; Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Feb 14; Vol. 22 (1), pp. 61. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cancer Vaccines*/therapeutic use
Neoplasms*/drug therapy
Nanoparticles*/therapeutic use
Humans ; Nanovaccines ; Immunotherapy ; Adjuvants, Immunologic
Czasopismo naukowe
Tytuł:
Personalized Cancer Vaccines Go Viral: Viral Vectors in the Era of Personalized Immunotherapy of Cancer.
Autorzy:
Seclì L; Nouscom, Via di Castel Romano 100, 00128 Rome, Italy.
Leoni G; Nouscom, Via di Castel Romano 100, 00128 Rome, Italy.
Ruzza V; Nouscom, Via di Castel Romano 100, 00128 Rome, Italy.
Siani L; Nouscom, Via di Castel Romano 100, 00128 Rome, Italy.
Cotugno G; Nouscom, Via di Castel Romano 100, 00128 Rome, Italy.
Scarselli E; Nouscom, Via di Castel Romano 100, 00128 Rome, Italy.
D'Alise AM; Nouscom, Via di Castel Romano 100, 00128 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 22; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cancer Vaccines*
Neoplasms*/therapy
Viral Vaccines*
Humans ; Immunotherapy ; Genetic Vectors/genetics ; Vaccination ; Antigens, Neoplasm
Czasopismo naukowe
Tytuł:
Virus-like particle-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice.
Autorzy:
Barajas A; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.; University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.
Amengual-Rigo P; Barcelona Supercomputing Center (BSC), Barcelona, Spain.
Pons-Grífols A; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.; Univeritat Autónoma de Barcelona (UAB), Cerdanyola, Spain.
Ortiz R; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.; Univeritat Autónoma de Barcelona (UAB), Cerdanyola, Spain.
Gracia Carmona O; Barcelona Supercomputing Center (BSC), Barcelona, Spain.
Urrea V; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.
de la Iglesia N; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.
Blanco-Heredia J; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.
Anjos-Souza C; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.
Varela I; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.
Trinité B; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.
Tarrés-Freixas F; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.
Rovirosa C; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.
Lepore R; Barcelona Supercomputing Center (BSC), Barcelona, Spain.
Vázquez M; Barcelona Supercomputing Center (BSC), Barcelona, Spain.
de Mattos-Arruda L; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.
Valencia A; Barcelona Supercomputing Center (BSC), Barcelona, Spain.
Clotet B; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.; University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.; Infectious Diseases Department, Germans Trias I Pujol Hospital, Badalona, Spain.
Aguilar-Gurrieri C; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain. .
Guallar V; Barcelona Supercomputing Center (BSC), Barcelona, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.
Carrillo J; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.; CIBER de Enfermedades Infecciosas, Madrid, Spain.
Blanco J; IrsiCaixa AIDS Research Institute, Crta del Canyet S/N., 08916, Badalona, Spain.; University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.; CIBER de Enfermedades Infecciosas, Madrid, Spain.; Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Jan 03; Vol. 22 (1), pp. 14. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/genetics
Vaccines*
Cancer Vaccines*
Humans ; Animals ; Mice ; Antigens, Neoplasm/metabolism ; Peptides ; Receptors, Antigen, T-Cell/metabolism ; Immunotherapy/methods
Czasopismo naukowe
Tytuł:
Enhancing immune responses of ESC-based TAA cancer vaccines with a novel OMV delivery system.
Autorzy:
Jin M; Chinese Academy of Sciences (CAS) Key Laboratory of Quantitative Engineering Biology, Shenzhen Institutes of Advanced Technology, Shenzhen Institute of Synthetic Biology, Chinese Academy of Sciences, Shenzhen, China.
Huo D; Chinese Academy of Sciences (CAS) Key Laboratory of Quantitative Engineering Biology, Shenzhen Institutes of Advanced Technology, Shenzhen Institute of Synthetic Biology, Chinese Academy of Sciences, Shenzhen, China.
Sun J; Chinese Academy of Sciences (CAS) Key Laboratory of Quantitative Engineering Biology, Shenzhen Institutes of Advanced Technology, Shenzhen Institute of Synthetic Biology, Chinese Academy of Sciences, Shenzhen, China.
Hu J
Liu S; Chinese Academy of Sciences (CAS) Key Laboratory of Quantitative Engineering Biology, Shenzhen Institutes of Advanced Technology, Shenzhen Institute of Synthetic Biology, Chinese Academy of Sciences, Shenzhen, China.
Zhan M; Chinese Academy of Sciences (CAS) Key Laboratory of Quantitative Engineering Biology, Shenzhen Institutes of Advanced Technology, Shenzhen Institute of Synthetic Biology, Chinese Academy of Sciences, Shenzhen, China.
Zhang BZ; Chinese Academy of Sciences (CAS) Key Laboratory of Quantitative Engineering Biology, Shenzhen Institutes of Advanced Technology, Shenzhen Institute of Synthetic Biology, Chinese Academy of Sciences, Shenzhen, China.
Huang JD; Chinese Academy of Sciences (CAS) Key Laboratory of Quantitative Engineering Biology, Shenzhen Institutes of Advanced Technology, Shenzhen Institute of Synthetic Biology, Chinese Academy of Sciences, Shenzhen, China. .; School of Biomedical Sciences, Faculty of Medicine, Li Ka Shing, The University of Hong Kong, Pokfulam, Hong Kong SAR, China. .; Department of Clinical Oncology, Shenzhen Key Laboratory for Cancer Metastasis and Personalized Therapy, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. .; Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen University, Guangzhou, 510120, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Jan 03; Vol. 22 (1), pp. 15. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Cancer Vaccines*
Neoplasms*/therapy
Animals ; Mice ; B7-H1 Antigen/metabolism ; Antibodies ; Antigens, Neoplasm ; Membrane Proteins ; Immunity ; Peptides ; Epitopes
Czasopismo naukowe
Tytuł:
Development of macrophage-associated genes prognostic signature predicts clinical outcome and immune infiltration for sepsis.
Autorzy:
Ma G; Department of Geriatric Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Wu X; Cancer Institute, Qingdao University, Qingdao, 266071, China.
Qi C; Qingdao Women and Children's Hospital, Qingdao, China.; Women and Children's Hospital, Qingdao University, Qingdao, China.
Yu X; Department of Geriatric Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. .
Zhang F; Department of Anesthesia, Dezhou Municipal Hospital, Dezhou, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 23; Vol. 14 (1), pp. 2026. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Sepsis*
Cancer Vaccines*
Humans ; Prognosis ; Cognition ; Genetic Risk Score ; Macrophages
Czasopismo naukowe
Tytuł:
Preclinical and Clinical Observations Implying Combination Therapy to Enhance the Efficacy of the Her-2/neu B-Cell Peptide-Based Vaccine HER-Vaxx and to Prevent Immune Evasion.
Autorzy:
Tobias J; Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.
Högler S; Institute of Pathology, Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.
Raigel M; Institute of Pathology, Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.
Lin DS; Department of Oncology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Chao Y; Department of Oncology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Kenner L; Department of Experimental Pathology, Medical University of Vienna, 1090 Vienna, Austria.
Garner-Spitzer E; Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.
Yavrom S; Imugene Limited, Sydney, NSW 2000, Australia.
Ede NJ; Imugene Limited, Sydney, NSW 2000, Australia.
Zielinski CC; Central European Cancer Center, Wiener Privatklinik, and Central European Cooperative Oncology Group (CECOG), 1090 Vienna, Austria.
Kundi M; Department of Environmental Health, Center for Public Health, Medical University of Vienna, 1090 Vienna, Austria.
Wiedermann U; Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 24; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*
Cancer Vaccines*/therapeutic use
Humans ; Animals ; Mice ; Immune Evasion ; In Situ Hybridization, Fluorescence ; Oncogenes ; Disease Progression
Czasopismo naukowe
Tytuł:
Fully Human Herpesvirus-Specific Neutralizing IgG Antibodies Generated by EBV Immortalization of Splenocytes-Derived from Immunized Humanized Mice.
Autorzy:
Theobald SJ; Department I of Internal Medicine, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.; Clinic of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany.; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, 30559 Hannover, Germany.
Fiestas E; Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health, 81377 Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377 Munich, Germany.; Institute of Structural Biology, Helmholtz Center Munich, German Research Center for Environmental Health, 81377 Munich, Germany.
Schneider A; Clinic of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany.; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, 30559 Hannover, Germany.
Ostermann B; Clinic of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany.; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, 30559 Hannover, Germany.
Danisch S; Clinic of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany.; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, 30559 Hannover, Germany.
von Kaisenberg C; Department of Obstetrics, Gynecology and Reproductive Medicine, Hannover Medical School, 30625 Hannover, Germany.
Rybniker J; Department I of Internal Medicine, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.
Hammerschmidt W; Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health, 81377 Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377 Munich, Germany.
Zeidler R; German Center for Infection Research (DZIF), Partner Site Munich, 81377 Munich, Germany.; Institute of Structural Biology, Helmholtz Center Munich, German Research Center for Environmental Health, 81377 Munich, Germany.; Department of Otorhinolaryngology, Munich University Hospital, 81377 Munich, Germany.
Stripecke R; Department I of Internal Medicine, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.; Clinic of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany.; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, 30559 Hannover, Germany.; Institute of Translational Immuno-Oncology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.; Cancer Research Center Cologne Essen, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
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Źródło:
Cells [Cells] 2023 Dec 21; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epstein-Barr Virus Infections*
Cancer Vaccines*
Humans ; Animals ; Mice ; Spleen ; Herpesvirus 4, Human ; Antibodies, Viral ; Immunoglobulin G ; Cytomegalovirus
Czasopismo naukowe

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