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Tytuł:
Scope and inclination of voluntary service for urban community-living older adults provided by volunteers with nursing background: A qualitative study.
Autorzy:
Huang L; Department of Nursing, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; School of Nursing,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu H; Department of Nursing, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang F; Department of Nursing, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Peng X; Health Science Center, Yangtze University, Jingzhou, China.
Guo L; School of Sociology, Huazhong University of Science and Technology, Wuhan, China.
Liao L; Department of Nursing, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; School of Nursing,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hu M; Department of Nursing, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang S; Department of Nursing, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Guan C; Department of Nursing, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu Y; Department of Nursing, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło:
Health expectations : an international journal of public participation in health care and health policy [Health Expect] 2024 Feb; Vol. 27 (1), pp. e13990.
Typ publikacji:
Journal Article
MeSH Terms:
Volunteers*
Aged ; Humans ; Qualitative Research ; Independent Living
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Volunteering on Heritage at Risk sites and wellbeing: A qualitative interview study.
Autorzy:
Pattinson J; Community and Health Research Unit (CaHRU), School of Health and Social Care, College of Social Science, University of Lincoln, Lincoln, UK.
Laparidou D; Community and Health Research Unit (CaHRU), School of Health and Social Care, College of Social Science, University of Lincoln, Lincoln, UK.
Akanuwe J; Primary Care and Public Health Research, Community and Health Research Unit (CaHRU), School of Health and Social Care, College of Social Science, University of Lincoln, Lincoln, UK.
Scott A; University of Lincoln College of Arts and Programme Manager Centre for Culture and Creativity, University of Lincoln, Lincoln, UK.
Sima C; Department of Marketing Languages and Tourism, Lincoln International Business School, University of Lincoln, Lincoln, UK.
Lewis C; University of Lincoln, Lincoln, UK.
Siriwardena N; Director of the University of Lincoln Community and Health Research Unit (CaHRU), School of Health and Social Care, College of Social Science, Lincoln, UK.
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Źródło:
Health expectations : an international journal of public participation in health care and health policy [Health Expect] 2023 Dec; Vol. 26 (6), pp. 2485-2499. Date of Electronic Publication: 2023 Aug 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Motivation*
Volunteers*/psychology
Humans ; Male ; Female ; Qualitative Research ; England ; Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Population pharmacokinetic modeling of oral brepocitinib in healthy volunteers and patients with immuno-inflammatory diseases.
Autorzy:
Maleki F; Clinical Pharmacology and Bioanalytics, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
Clark E; Department of Mathematics, University of Utah, Salt Lake City, Utah, USA.
Banfield C; Clinical Pharmacology and Bioanalytics, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
Byon W; Amador Bioscience, Ann Arbor, Michigan, USA.
Nicholas T; Clinical Pharmacology and Bioanalytics, Worldwide Research, Development and Medical, Pfizer Inc, Groton, Connecticut, USA.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Apr; Vol. 13 (4), pp. 551-562. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Janus Kinase Inhibitors*
Humans ; Male ; Female ; Healthy Volunteers ; Biological Availability ; Administration, Oral ; Body Weight ; Models, Biological
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Randomized, Open-Label, Phase I Clinical Study of Dalpiciclib With Different Specifications After Process Modification in Healthy Chinese Volunteers.
Autorzy:
Tao Y; Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Li T; Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Lin P; Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Jiang X; Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Shi P; Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Fu Y; Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Liu X; School of Pharmacy, Qingdao University, Qingdao, Shandong, China.
Wang C; Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Li S; Clinical Pharmacology Department, Jiangsu Hengrui Pharmaceuticals Co. Ltd., Jiangsu, China.
Li X; Clinical Pharmacology Department, Jiangsu Hengrui Pharmaceuticals Co. Ltd., Jiangsu, China.
Cao Y; Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Jan; Vol. 12 (1), pp. 65-69. Date of Electronic Publication: 2022 Oct 26.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
East Asian People*
Volunteers*
Adult ; Male ; Female ; Humans ; Chromatography, Liquid ; Mass Spectrometry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
College student motivations for and perceived impacts of volunteering with a nutrition and cooking education program for children.
Autorzy:
Soldavini J; Center for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Taillie LS; Carolina Population Center and Department of Nutrition, Gillings School of Global Public Health University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Lytle LA; Department of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Berner M; School of Government, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Ward DS; Center for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Ammerman A; Center for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
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Źródło:
Journal of community psychology [J Community Psychol] 2022 Jul; Vol. 50 (5), pp. 2104-2115. Date of Electronic Publication: 2021 Nov 25.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Motivation*
Volunteers*
Child ; Cooking ; Humans ; Students ; Surveys and Questionnaires
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Population pharmacokinetic analysis of sparsentan in healthy volunteers and patients with focal segmental glomerulosclerosis.
Autorzy:
Wada R; Certara, Inc., Menlo Park, California, USA.
Kleijn HJ; Certara, Inc., Menlo Park, California, USA.
Zhang L; Certara, Inc., Menlo Park, California, USA.
Chen SC; Travere Therapeutics, Inc., San Diego, California, USA.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Aug; Vol. 12 (8), pp. 1080-1092. Date of Electronic Publication: 2023 Jun 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glomerulosclerosis, Focal Segmental*/drug therapy
Spiro Compounds*
Humans ; Cytochrome P-450 CYP3A Inhibitors ; Healthy Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
First-in-Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Pirepemat, a Cortical Enhancer, in Healthy Volunteers.
Autorzy:
Rein-Hedin E; CTC Clinical Trial Consultants AB, Uppsala, Sweden.; Department of Surgical Sciences, Plastic Surgery, Uppsala University, Uppsala, Sweden.
Sjöberg F; CTC Clinical Trial Consultants AB, Uppsala, Sweden.; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Waters S; Integrative Research Laboratories Sweden AB, Gothenburg, Sweden.
Sonesson C; Integrative Research Laboratories Sweden AB, Gothenburg, Sweden.
Waters N; Integrative Research Laboratories Sweden AB, Gothenburg, Sweden.
Huss F; CTC Clinical Trial Consultants AB, Uppsala, Sweden.; Department of Surgical Sciences, Plastic Surgery, Uppsala University, Uppsala, Sweden.
Tedroff J; Integrative Research Laboratories Sweden AB, Gothenburg, Sweden.; Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2021 Dec; Vol. 10 (12), pp. 1485-1494. Date of Electronic Publication: 2021 Jun 12.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Healthy Volunteers*
Area Under Curve ; Dose-Response Relationship, Drug ; Double-Blind Method ; Drug Administration Schedule ; Humans ; Male
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Exploring the co-benefits of environmental volunteering for human and planetary health promotion.
Autorzy:
Patrick R; Health Nature Sustainability Research Group, School of Health and Social Development, Faculty of Health, Deakin University, Burwood, Australia.
Henderson-Wilson C; Health Nature Sustainability Research Group, School of Health and Social Development, Faculty of Health, Deakin University, Burwood, Australia.
Ebden M; Health Nature Sustainability Research Group, School of Health and Social Development, Faculty of Health, Deakin University, Burwood, Australia.
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Źródło:
Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals [Health Promot J Austr] 2022 Jan; Vol. 33 (1), pp. 57-67. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Health Promotion*
Volunteers*
Conservation of Natural Resources ; Employment ; Humans ; Motivation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Randomized, Double-Blind, Controlled Study to Evaluate Safety and Pharmacokinetics of Single Ascending Doses of ASP5354, an Investigational Imaging Product, in Healthy Adult Volunteers.
Autorzy:
Murase T; Astellas Pharma Inc, Tokyo, Japan.
Takizawa M; Astellas Pharma Inc, Tokyo, Japan.
Galitz L; Labcorp Drug Development Inc., Daytona, Florida, USA.
Flach S; Labcorp Drub Development Inc, Madison, Wisconsin, USA.
Murray V; Labcorp Drug Development Inc, Leeds, UK.
Gufford B; Labcorp Drub Development Inc, Madison, Wisconsin, USA.
Suwa A; Rx+ Business Accelerator, Astellas Pharma Inc, Ibaraki, Japan.
Pokaż więcej
Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2021 Dec; Vol. 10 (12), pp. 1460-1468. Date of Electronic Publication: 2021 Aug 23.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Healthy Volunteers*
Adult ; Area Under Curve ; Double-Blind Method ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Aspects of the volunteering experience associated with well-being in older adults.
Autorzy:
Jongenelis MI; Melbourne Centre for Behaviour Change, Melbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC, Australia.
Pettigrew S; The George Institute for Global Health, Sydney, Australia.; School of Public Health and Community Medicine, University of New South Wales, Sydney, Australia.
Pokaż więcej
Źródło:
Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals [Health Promot J Austr] 2021 Oct; Vol. 32 Suppl 2, pp. 384-390. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji:
Journal Article
MeSH Terms:
Mental Health*
Volunteers*
Aged ; Female ; Humans ; Male
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evaluation of a Low-Fat Low-Calorie Meal on the Relative Bioavailability of Trametinib and Dabrafenib: Results From a Randomized, Open-Label, 2-Part Study in Healthy Participants.
Autorzy:
Tan EY; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
Pazdirkova M; Novartis, Prague, Czech Republic.
Taylor AJ; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
Singh N; Novartis Healthcare Private Limited, Hyderabad, India.
Iyer GR; Novartis Institute of Biomedical Research Inc., Cambridge, Massachusetts, USA.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Mar; Vol. 12 (3), pp. 333-342. Date of Electronic Publication: 2023 Jan 20.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fasting*
Humans ; Biological Availability ; Healthy Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pharmacokinetics, Bioequivalence, and Safety Evaluation of Dienogest in Healthy Subjects Under Fasting and Fed Conditions.
Autorzy:
Zhao D; Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing, China.
Ni J; Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing, China.
Zhang W; Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing, China.
Zhou Y; Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing, China.
Chang D; China Resources Zizhu Pharmaceutical Co., Chaoyang District, Beijing, China.
Yang Z; China Resources Zizhu Pharmaceutical Co., Chaoyang District, Beijing, China.
Wang Y; China Resources Zizhu Pharmaceutical Co., Chaoyang District, Beijing, China.
Zhao X; Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing, China.
Hao X; Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing, China.
Pokaż więcej
Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Apr; Vol. 12 (4), pp. 350-355. Date of Electronic Publication: 2023 Jan 30.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fasting*
Humans ; Female ; Therapeutic Equivalency ; Healthy Volunteers ; Area Under Curve
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Phase 1 Study to Evaluate Absolute Bioavailability and Absorption, Distribution, Metabolism, and Excretion of Savolitinib in Healthy Male Volunteers.
Autorzy:
Miah K; Clinical Pharmacology & Quantitative Pharmacology, CPSS, AstraZeneca, Boston, Massachusetts, USA.
Vishwanathan K; Clinical Pharmacology & Quantitative Pharmacology, CPSS, AstraZeneca, Boston, Massachusetts, USA.
Scarfe G; Drug Metabolism and Pharmacokinetics, Oncology R&D, Research & Early Development, AstraZeneca, Cambridge, UK.
Li Y; Clinical Pharmacology & Quantitative Pharmacology, CPSS, AstraZeneca, Boston, Massachusetts, USA.
Hara I; Drug Metabolism and Pharmacokinetics, Oncology R&D, Research & Early Development, AstraZeneca, Cambridge, UK.
Cantarini M; Global Medicines Department Oncology, AstraZeneca, Cambridge, UK.
Argue J; Oncology Biometrics, Oncology R&D, AstraZeneca, Cambridge, UK.
Menakuru SR; Quotient Sciences, Nottingham, UK.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Apr; Vol. 12 (4), pp. 424-435. Date of Electronic Publication: 2023 Feb 19.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pyrazines*/adverse effects
Triazines*
Adult ; Humans ; Male ; Biological Availability ; Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Three-Period Bioequivalence Study of Sodium Levofolinate Injection With Calcium Levofolinate for Injection and Sodium Folinate for Injection in Healthy Chinese Subjects.
Autorzy:
Qiu B; School of Pharmacy, Wannan Medical College, Wuhu, Anhui, People's Republic of China.
Liu G; School of Pharmacy, Wannan Medical College, Wuhu, Anhui, People's Republic of China.
Wang C; School of Pharmacy, Wannan Medical College, Wuhu, Anhui, People's Republic of China.
Chen X; School of Pharmacy, Wannan Medical College, Wuhu, Anhui, People's Republic of China.
Liu R; School of Pharmacy, Wannan Medical College, Wuhu, Anhui, People's Republic of China.
Huang Y; School of Pharmacy, Wannan Medical College, Wuhu, Anhui, People's Republic of China.
Jia Y; Anhui Provincial Center of Drug Clinical Evaluation, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui, People's Republic of China.
Shen J; School of Pharmacy, Wannan Medical College, Wuhu, Anhui, People's Republic of China.; Anhui Provincial Center of Drug Clinical Evaluation, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui, People's Republic of China.
Pokaż więcej
Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Apr; Vol. 12 (4), pp. 416-423. Date of Electronic Publication: 2023 Feb 19.
Typ publikacji:
Equivalence Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
East Asian People*
Levoleucovorin*/chemistry
Levoleucovorin*/pharmacokinetics
Leucovorin*/chemistry
Leucovorin*/pharmacokinetics
Humans ; Healthy Volunteers ; Therapeutic Equivalency
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Food and Multiple-dose Administration on the Pharmacokinetic Properties of HR20033, a Sustained-release Formulation of Henagliflozin and Metformin for the Treatment of Diabetes, in Healthy Chinese Volunteers.
Autorzy:
Liu Y; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, China.
Huyan X; The First Health Care Department, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Zhang Q; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, China.
Qing H; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, China.
Zhang Q; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, China.
Wang X; Department of Clinical Pharmacology, Jiangsu Hengrui Pharmaceuticals Co, Ltd., Jiangsu, China.
Li Y; Department of Statistics and Programming, Jiangsu Hengrui Pharmaceuticals Co, Ltd., Jiangsu, China.
Liu Z; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, China.
Hu W; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, China.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Apr; Vol. 12 (4), pp. 376-384. Date of Electronic Publication: 2022 Nov 21.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Metformin*/pharmacokinetics
Diabetes Mellitus, Type 2*/drug therapy
Sodium-Glucose Transporter 2 Inhibitors*
Humans ; Hypoglycemic Agents/pharmacokinetics ; Healthy Volunteers ; Delayed-Action Preparations ; East Asian People ; Area Under Curve
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E6742, a Dual Antagonist of Toll-like Receptors 7 and 8, in Healthy Volunteers.
Autorzy:
Yamakawa N; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
Tago F; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
Nakai K; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
Kitahara Y; Eisai Inc., Nutley, New Jersey, USA.
Ikari S; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
Hojo S; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
Hall N; Eisai Inc., Nutley, New Jersey, USA.
Aluri J; Eisai Inc., Nutley, New Jersey, USA.
Hussein Z; Eisai Ltd., Hatfield, UK.
Gevorkyan H; California Clinical Trials Medical Group in affiliation with PAREXEL, Glendale, Glendale, California, USA.
Maruyama T; Clinical Research Promotion Center, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Ishizaka S; Eisai Inc./Eisai Center for Genetics Guided Dementia Discovery, Cambridge, Massachusetts, USA.
Yagi T; Eisai Inc., Nutley, New Jersey, USA.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Apr; Vol. 12 (4), pp. 363-375. Date of Electronic Publication: 2022 Oct 11.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Toll-Like Receptor 7*
Fasting*
Humans ; Area Under Curve ; Healthy Volunteers ; Double-Blind Method
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Single Oral Dose of SHR4640, a Selective Urate Transporter 1 Inhibitor, in Healthy Chinese Male Volunteers.
Autorzy:
Liang B; Department of Pharmacy, Medical Supplier Center, Center of Medicine Clinical Research, PLA General Hospital, Beijing, China.
Wang J; Department of Pharmacy, Medical Supplier Center, Center of Medicine Clinical Research, PLA General Hospital, Beijing, China.
Bai N; Department of Pharmacy, Medical Supplier Center, Center of Medicine Clinical Research, PLA General Hospital, Beijing, China.
Zhuo J; Department of Pharmacy, Medical Supplier Center, Center of Medicine Clinical Research, PLA General Hospital, Beijing, China.
Wang R; Department of Pharmacy, Medical Supplier Center, Center of Medicine Clinical Research, PLA General Hospital, Beijing, China.
Lin H; Department of Clinical Pharmacology, Jiangsu Hengrui Medicine Co. Ltd, Shanghai, China.
Cai Y; Department of Pharmacy, Medical Supplier Center, Center of Medicine Clinical Research, PLA General Hospital, Beijing, China.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Apr; Vol. 12 (4), pp. 392-396. Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Uric Acid*
East Asian People*
Humans ; Male ; Healthy Volunteers ; Area Under Curve ; Uricosuric Agents/pharmacokinetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Single-dose, Two-Period Crossover Bioequivalence Study Comparing Two Liraglutide Formulations in Healthy Chinese Subjects.
Autorzy:
Feng S; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Cai L; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Wang X; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, China.
Yu Q; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Cai J; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, China.
Hao W; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, China.
Chen Z; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Su X; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Du C; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Zou Q; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Guo W; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Du D; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Hu F; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Li F; Institute of Drug Clinical Trial·GCP, West China Second University Hospital, Sichuan University, Chengdu, China.; College of Pharmacy, Chongqing Medical University, Chongqing, China.
Liu Y; Chongqing Chenan Biopharmaceutical Co. Ltd., Chengdu, China.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Apr; Vol. 12 (4), pp. 385-391. Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:
Equivalence Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*/drug therapy
Liraglutide*/therapeutic use
Humans ; East Asian People ; Healthy Volunteers ; Therapeutic Equivalency
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of a High-Fat Meal on Single-Dose Rencofilstat (CRV431) Oral Bioavailability in Healthy Human Subjects.
Autorzy:
Remenchik E; Worldwide Clinical Trials, Morrisville, North Carolina, USA.
Mayo PR; Hepion Pharmaceuticals, Edison, New Jersey, USA.
Hobbs TM; Hepion Pharmaceuticals, Edison, New Jersey, USA.
Greytok JA; Hepion Pharmaceuticals, Edison, New Jersey, USA.
Foster EP; Hepion Pharmaceuticals, Edison, New Jersey, USA.
Zhao C; Hepion Pharmaceuticals, Edison, New Jersey, USA.
Ure D; Hepion Pharmaceuticals, Edison, New Jersey, USA.
Trepanier DJ; Hepion Pharmaceuticals, Edison, New Jersey, USA.
Foster RT; Hepion Pharmaceuticals, Edison, New Jersey, USA.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Mar; Vol. 12 (3), pp. 287-293. Date of Electronic Publication: 2022 Oct 17.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
MeSH Terms:
Meals*
Humans ; Administration, Oral ; Biological Availability ; Healthy Volunteers
Czasopismo naukowe
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Tytuł:
Effect of Futibatinib on Cardiac Repolarization: Results of a Randomized, Controlled, Double-Blind, QT/QTc, Phase 1 Study in Healthy Subjects.
Autorzy:
Yamamiya I; Taiho Oncology, Inc., Princeton, New Jersey, USA.
Lester R; Celerion, Tempe, Arizona, USA.
Sonnichsen D; Sonnichsen Pharmaceutical Associates, LLC, Collegeville, Pennsylvania, USA.
Mina M; Taiho Oncology, Inc., Princeton, New Jersey, USA.
He Y; Taiho Oncology, Inc., Princeton, New Jersey, USA.
Benhadji KA; Taiho Oncology, Inc., Princeton, New Jersey, USA.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Mar; Vol. 12 (3), pp. 304-313. Date of Electronic Publication: 2022 Nov 20.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fluoroquinolones*/adverse effects
Heart*
Humans ; Moxifloxacin/adverse effects ; Healthy Volunteers
Czasopismo naukowe
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