Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Vaccines, Synthetic"" wg kryterium: Temat


Tytuł :
Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines.
Autorzy :
Moghimi SM; School of Pharmacy, Newcastle University, Newcastle upon Tyne NE1 7RU, UK; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. Electronic address: .
Pokaż więcej
Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Mar 03; Vol. 29 (3), pp. 898-900. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anaphylaxis/*chemically induced
COVID-19/*prevention & control
COVID-19 Vaccines/*adverse effects
Liposomes/*adverse effects
Nanoparticles/*adverse effects
Vaccines, Synthetic/*adverse effects
Amino Alcohols/adverse effects ; Amino Alcohols/chemistry ; Anaphylaxis/diagnosis ; Anaphylaxis/pathology ; COVID-19/immunology ; COVID-19/pathology ; COVID-19/virology ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/chemistry ; Decanoates/adverse effects ; Decanoates/chemistry ; Excipients/adverse effects ; Excipients/chemistry ; Humans ; Liposomes/administration & dosage ; Liposomes/immunology ; Mass Vaccination/statistics & numerical data ; Nanoparticles/administration & dosage ; Polyethylene Glycols/adverse effects ; Polyethylene Glycols/chemistry ; SARS-CoV-2/pathogenicity ; Vaccines, Synthetic/administration & dosage ; Vaccines, Synthetic/chemistry
Czasopismo naukowe
Tytuł :
Advances in gene-based vaccine platforms to address the COVID-19 pandemic.
Autorzy :
Pushparajah D; School of Pharmacy, University of Waterloo, 10A Victoria St S, Kitchener N2G 1C5, Canada.
Jimenez S; School of Pharmacy, University of Waterloo, 10A Victoria St S, Kitchener N2G 1C5, Canada; Theraphage, 151 Charles St W Suite # 199, Kitchener, ON, N2G 1H6, Canada.
Wong S; School of Pharmacy, University of Waterloo, 10A Victoria St S, Kitchener N2G 1C5, Canada.
Alattas H; School of Pharmacy, University of Waterloo, 10A Victoria St S, Kitchener N2G 1C5, Canada.
Nafissi N; Mediphage Bioceuticals, 661 University Avenue, Suite 1300, Toronto, ON, M5G 0B7, Canada.
Slavcev RA; School of Pharmacy, University of Waterloo, 10A Victoria St S, Kitchener N2G 1C5, Canada; Mediphage Bioceuticals, 661 University Avenue, Suite 1300, Toronto, ON, M5G 0B7, Canada; Theraphage, 151 Charles St W Suite # 199, Kitchener, ON, N2G 1H6, Canada. Electronic address: .
Pokaż więcej
Źródło :
Advanced drug delivery reviews [Adv Drug Deliv Rev] 2021 Mar; Vol. 170, pp. 113-141. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*prevention & control
COVID-19 Vaccines/*administration & dosage
Pandemics/*prevention & control
SARS-CoV-2/*drug effects
Vaccines, Synthetic/*administration & dosage
Viral Vaccines/*administration & dosage
Animals ; COVID-19/epidemiology ; COVID-19/genetics ; COVID-19/immunology ; COVID-19 Vaccines/genetics ; COVID-19 Vaccines/immunology ; Clinical Trials as Topic/methods ; Humans ; SARS-CoV-2/genetics ; SARS-CoV-2/immunology ; Vaccines, Synthetic/genetics ; Vaccines, Synthetic/immunology ; Viral Vaccines/genetics ; Viral Vaccines/immunology
Czasopismo naukowe
Tytuł :
Self-assembled mRNA vaccines.
Autorzy :
Kim J; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Science Building, 2730 South Moody Avenue, Portland, Oregon 97201, USA.
Eygeris Y; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Science Building, 2730 South Moody Avenue, Portland, Oregon 97201, USA.
Gupta M; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Science Building, 2730 South Moody Avenue, Portland, Oregon 97201, USA.
Sahay G; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Robertson Life Science Building, 2730 South Moody Avenue, Portland, Oregon 97201, USA; Department of Biomedical Engineering, Oregon Health & Science University, Robertson Life Science Building, 2730 South Moody Avenue, Portland, Oregon 97201, USA; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon 97239, USA. Electronic address: .
Pokaż więcej
Źródło :
Advanced drug delivery reviews [Adv Drug Deliv Rev] 2021 Mar; Vol. 170, pp. 83-112. Date of Electronic Publication: 2021 Jan 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Design*
Gene Transfer Techniques*/trends
COVID-19 Vaccines/*administration & dosage
Nanotechnology/*methods
RNA, Messenger/*administration & dosage
Vaccines, Synthetic/*administration & dosage
Animals ; COVID-19 Vaccines/genetics ; COVID-19 Vaccines/immunology ; Humans ; Nanoparticles/administration & dosage ; Nanotechnology/trends ; RNA, Messenger/genetics ; RNA, Messenger/immunology ; Vaccines, Synthetic/genetics ; Vaccines, Synthetic/immunology
Czasopismo naukowe
Tytuł :
mRNA vaccine: a potential therapeutic strategy.
Autorzy :
Wang Y; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan, 610041, PR China.
Zhang Z; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan, 610041, PR China.
Luo J; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan, 610041, PR China.
Han X; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan, 610041, PR China.
Wei Y; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan, 610041, PR China.
Wei X; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan, 610041, PR China. .
Pokaż więcej
Źródło :
Molecular cancer [Mol Cancer] 2021 Feb 16; Vol. 20 (1), pp. 33. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Vaccines, Synthetic/*therapeutic use
Animals ; COVID-19/immunology ; Gene Transfer Techniques ; Humans ; Immunity, Humoral ; Immunotherapy ; RNA Stability ; Vaccines, Synthetic/genetics ; Vaccines, Synthetic/immunology
Czasopismo naukowe
Tytuł :
Synthetic Messenger RNA-Based Vaccines: from Scorn to Hype.
Autorzy :
Pascolo S; Department of Dermatology, University Hospital Zürich (USZ), University of Zürich (UZH), Raemistrasse 100, 8091 Zürich, Switzerland.
Pokaż więcej
Źródło :
Viruses [Viruses] 2021 Feb 09; Vol. 13 (2). Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*prevention & control
COVID-19 Vaccines/*immunology
SARS-CoV-2/*immunology
Vaccines, Synthetic/*immunology
Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/adverse effects ; COVID-19 Vaccines/genetics ; Humans ; Pandemics ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology ; Vaccines, Synthetic/administration & dosage ; Vaccines, Synthetic/adverse effects ; Vaccines, Synthetic/genetics
Czasopismo naukowe
Tytuł :
Non-viral COVID-19 vaccine delivery systems.
Autorzy :
Park KS; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Sun X; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA.
Aikins ME; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA.
Moon JJ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: .
Pokaż więcej
Źródło :
Advanced drug delivery reviews [Adv Drug Deliv Rev] 2021 Feb; Vol. 169, pp. 137-151. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*prevention & control
COVID-19 Vaccines/*administration & dosage
Drug Delivery Systems/*methods
Vaccines, Synthetic/*administration & dosage
Animals ; COVID-19/genetics ; COVID-19 Vaccines/chemistry ; COVID-19 Vaccines/genetics ; Humans ; Vaccines, DNA/administration & dosage ; Vaccines, DNA/chemistry ; Vaccines, DNA/genetics ; Vaccines, Synthetic/chemistry ; Vaccines, Synthetic/genetics
Czasopismo naukowe
Tytuł :
A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike.
Autorzy :
Lu M; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
Dravid P; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.
Zhang Y; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
Trivedi S; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.
Li A; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
Harder O; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
Kc M; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.
Chaiwatpongsakorn S; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.
Zani A; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH 43210.
Kenney A; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH 43210.
Zeng C; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
Cai C; Department of Surgery, College of Medicine, The Ohio State University, Columbus, OH 43210.
Ye C; Texas Biomedical Research Institute, San Antonio, TX 78227.
Liang X; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
Shimamura M; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH 43210.
Liu SL; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH 43210.; Infectious Disease Institute, The Ohio State University, Columbus, OH 43210.; Center for Retrovirus Research, The Ohio State University, Columbus, OH 43210.
Mejias A; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH 43210.
Ramilo O; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH 43210.
Boyaka PN; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.; Infectious Disease Institute, The Ohio State University, Columbus, OH 43210.
Qiu J; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160.
Martinez-Sobrido L; Texas Biomedical Research Institute, San Antonio, TX 78227.
Yount JS; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH 43210.; Infectious Disease Institute, The Ohio State University, Columbus, OH 43210.
Peeples ME; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH 43210.; Infectious Disease Institute, The Ohio State University, Columbus, OH 43210.
Kapoor A; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH 43210.; Infectious Disease Institute, The Ohio State University, Columbus, OH 43210.
Niewiesk S; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.; Infectious Disease Institute, The Ohio State University, Columbus, OH 43210.
Li J; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210; .; Infectious Disease Institute, The Ohio State University, Columbus, OH 43210.
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Mar 23; Vol. 118 (12).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Vectors*/genetics
Genetic Vectors*/immunology
Measles virus*/genetics
Measles virus*/immunology
COVID-19/*prevention & control
COVID-19 Vaccines/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Vaccines, Synthetic/*immunology
Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; COVID-19/complications ; COVID-19/pathology ; COVID-19 Vaccines/genetics ; Cricetinae ; Disease Models, Animal ; Gene Expression ; Humans ; Immunization ; Immunogenicity, Vaccine ; Mice ; Mice, Transgenic ; Rats ; Spike Glycoprotein, Coronavirus/genetics ; Vaccines, Synthetic/genetics
Czasopismo naukowe
Tytuł :
Mini Review Immunological Consequences of Immunization With COVID-19 mRNA Vaccines: Preliminary Results.
Autorzy :
Lombardi A; Infectious Diseases Unit, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milano, Milan, Italy.
Bozzi G; Infectious Diseases Unit, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Ungaro R; Infectious Diseases Unit, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Villa S; Center for Multidisciplinary Research in Health Science (MACH), University of Milano, Milan, Italy.
Castelli V; Infectious Diseases Unit, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Mangioni D; Infectious Diseases Unit, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Muscatello A; Infectious Diseases Unit, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Gori A; Infectious Diseases Unit, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milano, Milan, Italy.; Center for Multidisciplinary Research in Health Science (MACH), University of Milano, Milan, Italy.
Bandera A; Infectious Diseases Unit, Foundation Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milano, Milan, Italy.; Center for Multidisciplinary Research in Health Science (MACH), University of Milano, Milan, Italy.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2021 Mar 12; Vol. 12, pp. 657711. Date of Electronic Publication: 2021 Mar 12 (Print Publication: 2021).
Typ publikacji :
Journal Article; Review
MeSH Terms :
Immunization*
Immunogenicity, Vaccine*
COVID-19/*prevention & control
COVID-19 Vaccines/*therapeutic use
SARS-CoV-2/*immunology
Vaccines, Synthetic/*therapeutic use
Animals ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; COVID-19/blood ; COVID-19/immunology ; COVID-19/virology ; COVID-19 Vaccines/adverse effects ; Diffusion of Innovation ; Host-Pathogen Interactions ; Humans ; SARS-CoV-2/genetics ; Treatment Outcome ; Vaccines, Synthetic/adverse effects
Czasopismo naukowe
Tytuł :
Innate Inhibiting Proteins Enhance Expression and Immunogenicity of Self-Amplifying RNA.
Autorzy :
Blakney AK; Department of Infectious Disease, Imperial College London, London W21PG, UK. Electronic address: .
McKay PF; Department of Infectious Disease, Imperial College London, London W21PG, UK.
Bouton CR; Department of Infectious Disease, Imperial College London, London W21PG, UK.
Hu K; Department of Infectious Disease, Imperial College London, London W21PG, UK.
Samnuan K; Department of Infectious Disease, Imperial College London, London W21PG, UK.
Shattock RJ; Department of Infectious Disease, Imperial College London, London W21PG, UK. Electronic address: .
Pokaż więcej
Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Mar 03; Vol. 29 (3), pp. 1174-1185. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunogenicity, Vaccine*
Immunity, Innate/*drug effects
Protein Biosynthesis/*drug effects
Vaccines, Synthetic/*pharmacology
Viral Envelope Proteins/*administration & dosage
Animals ; Cell Line ; Encephalitis Virus, Venezuelan Equine/drug effects ; Encephalitis Virus, Venezuelan Equine/immunology ; Encephalitis Virus, Venezuelan Equine/pathogenicity ; Fibroblasts ; Gene Expression Regulation ; HeLa Cells ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/immunology ; Humans ; Immunoglobulin G/biosynthesis ; Interferon Regulatory Factor-3/genetics ; Interferon Regulatory Factor-3/immunology ; Janus Kinases/antagonists & inhibitors ; Janus Kinases/genetics ; Janus Kinases/immunology ; Mice ; Middle East Respiratory Syndrome Coronavirus/drug effects ; Middle East Respiratory Syndrome Coronavirus/immunology ; Middle East Respiratory Syndrome Coronavirus/pathogenicity ; NF-kappa B/genetics ; NF-kappa B/immunology ; Parainfluenza Virus 5/drug effects ; Parainfluenza Virus 5/immunology ; Parainfluenza Virus 5/pathogenicity ; Pyrazoles/pharmacology ; Rabbits ; Rabies virus/drug effects ; Rabies virus/immunology ; Rabies virus/pathogenicity ; Rats ; STAT Transcription Factors/antagonists & inhibitors ; STAT Transcription Factors/genetics ; STAT Transcription Factors/immunology ; Signal Transduction ; Vaccines, Synthetic/biosynthesis ; Viral Envelope Proteins/genetics ; Viral Envelope Proteins/immunology
Czasopismo naukowe
Tytuł :
Nanoparticle-Mediated Cytoplasmic Delivery of Messenger RNA Vaccines: Challenges and Future Perspectives.
Autorzy :
Wu Z; School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, 1142, New Zealand. .
Li T; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana, 47907, USA.
Pokaż więcej
Źródło :
Pharmaceutical research [Pharm Res] 2021 Mar; Vol. 38 (3), pp. 473-478. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Carriers*
Nanoparticles*
COVID-19/*prevention & control
COVID-19 Vaccines/*therapeutic use
Cytoplasm/*metabolism
Lipids/*chemistry
Ribosomes/*metabolism
Vaccines, Synthetic/*therapeutic use
Animals ; COVID-19/immunology ; COVID-19/virology ; COVID-19 Vaccines/chemistry ; COVID-19 Vaccines/pharmacokinetics ; Drug Compounding ; Humans ; Nanomedicine ; Vaccines, Synthetic/chemistry
Czasopismo naukowe
Tytuł :
Addressing the Cold Reality of mRNA Vaccine Stability.
Autorzy :
Crommelin DJA; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, (UIPS), Faculty of Science, Utrecht University, Utrecht, the Netherlands. Electronic address: .
Anchordoquy TJ; Skaggs School of Pharmacy and Pharmaceutical Sciences, Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA.
Volkin DB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS 66047, USA.
Jiskoot W; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.
Mastrobattista E; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, (UIPS), Faculty of Science, Utrecht University, Utrecht, the Netherlands. Electronic address: .
Pokaż więcej
Źródło :
Journal of pharmaceutical sciences [J Pharm Sci] 2021 Mar; Vol. 110 (3), pp. 997-1001. Date of Electronic Publication: 2020 Dec 13.
Typ publikacji :
Journal Article
MeSH Terms :
Vaccine Potency*
COVID-19/*prevention & control
COVID-19 Vaccines/*chemistry
Vaccines, Synthetic/*chemistry
COVID-19/immunology ; COVID-19 Vaccines/immunology ; Cold Temperature ; Drug Stability ; Drug Storage/methods ; Humans ; RNA Stability ; RNA, Messenger/chemistry ; RNA, Messenger/immunology ; SARS-CoV-2/immunology ; Vaccines, Synthetic/immunology
Czasopismo naukowe
Tytuł :
mRNA vaccine for cancer immunotherapy.
Autorzy :
Miao L; Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Zhang Y; Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Huang L; Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA. .
Pokaż więcej
Źródło :
Molecular cancer [Mol Cancer] 2021 Feb 25; Vol. 20 (1), pp. 41. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Cancer Vaccines/*immunology
Immunotherapy/*methods
Neoplasms/*therapy
Vaccines, Synthetic/*immunology
Animals ; COVID-19/immunology ; COVID-19/therapy ; COVID-19/virology ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/immunology ; Cancer Vaccines/administration & dosage ; Humans ; Neoplasms/immunology ; SARS-CoV-2/immunology ; SARS-CoV-2/physiology ; Vaccines, Synthetic/administration & dosage ; Vaccinology/methods ; Vaccinology/trends
Czasopismo naukowe
Tytuł :
The Century of mRNA Vaccines: COVID-19 Vaccines and Allergy.
Autorzy :
Ortega Rodríguez NR; Servicio de Alergia e Inmunología Clínica, HU de Gran Canaria Dr Negrín ULPGC, Las Palmas, Spain.; Spanish Society of Allergology and Clinical Immunology (SEAIC) Group.
Audícana Berasategui MT; Servicio de Alergia e Inmunología Clínica. HU Araba, Vitoria- Gasteiz, Spain.; Spanish Society of Allergology and Clinical Immunology (SEAIC) Group.
de la Hoz Caballer B; Servicio de Alergia, HU Ramón y Cajal, Madrid, Spain.; Spanish Society of Allergology and Clinical Immunology (SEAIC) Group.
Valero Santiago A; Sección de Alergología, Hospital Clínic, IDIBAPS, Barcelona, Spain.; Spanish Society of Allergology and Clinical Immunology (SEAIC) Group.
Pokaż więcej
Źródło :
Journal of investigational allergology & clinical immunology [J Investig Allergol Clin Immunol] 2021 Feb 17; Vol. 31 (1), pp. 89-91. Date of Electronic Publication: 2020 Jan 04.
Typ publikacji :
Letter
MeSH Terms :
Mass Vaccination*/adverse effects
COVID-19/*prevention & control
COVID-19 Vaccines/*therapeutic use
Hypersensitivity/*therapy
SARS-CoV-2/*immunology
Vaccines, Synthetic/*therapeutic use
COVID-19/immunology ; COVID-19/virology ; COVID-19 Vaccines/adverse effects ; Drug Hypersensitivity/immunology ; Drug Hypersensitivity/prevention & control ; Host-Pathogen Interactions ; Humans ; Hypersensitivity/diagnosis ; Hypersensitivity/immunology ; Immunocompromised Host ; Patient Safety ; Risk Assessment ; Risk Factors ; Vaccines, Synthetic/adverse effects
Opinia redakcyjna
Tytuł :
Infectious RNA vaccine protects mice against chikungunya virus infection.
Autorzy :
Szurgot I; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 77, Stockholm, Sweden. .
Ljungberg K; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 77, Stockholm, Sweden.; Eurocine Vaccines AB, Karolinska Institutet Science Park, 171 65, Solna, Sweden.
Kümmerer BM; Institute of Virology, Medical Faculty, University of Bonn, Bonn, Germany.
Liljeström P; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 77, Stockholm, Sweden.
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2020 Dec 03; Vol. 10 (1), pp. 21076. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chikungunya Fever/*prevention & control
Vaccines, Synthetic/*immunology
Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Chikungunya Fever/immunology ; Chikungunya Fever/virology ; Chikungunya virus/genetics ; Chikungunya virus/immunology ; Chikungunya virus/pathogenicity ; Female ; Immunogenicity, Vaccine ; Injections, Intramuscular ; Mice ; Mice, Inbred C57BL ; Mutation ; Vaccines, Attenuated/administration & dosage ; Vaccines, Attenuated/genetics ; Vaccines, Attenuated/immunology ; Vaccines, Synthetic/administration & dosage ; Vaccines, Synthetic/genetics ; Viral Nonstructural Proteins/genetics ; Viral Nonstructural Proteins/immunology
Czasopismo naukowe
Tytuł :
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis.
Autorzy :
Krienke C; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.; Research Center for Immunotherapy (FZI), University Medical Center at the Johannes Gutenberg University, Langenbeckstr. 1, Mainz 55131, Germany.
Kolb L; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Diken E; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Streuber M; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Kirchhoff S; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Bukur T; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Akilli-Öztürk Ö; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Kranz LM; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Berger H; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Petschenka J; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.; Cancer Immunology and Immune Modulation, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397 Biberach an der Riss, Germany.
Diken M; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Kreiter S; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Yogev N; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University, Mainz 55131, Germany.; Clinic and Polyclinic for Dermatology and Venereology, University Hospital Cologne, Kerpenerstr. 62, Cologne 50937, Germany.
Waisman A; Research Center for Immunotherapy (FZI), University Medical Center at the Johannes Gutenberg University, Langenbeckstr. 1, Mainz 55131, Germany.; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University, Mainz 55131, Germany.
Karikó K; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Türeci Ö; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.; CI3 - Cluster for Individualized Immunointervention e.V., Hölderlinstraße 8, 55131 Mainz, Germany.
Sahin U; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany. .; Research Center for Immunotherapy (FZI), University Medical Center at the Johannes Gutenberg University, Langenbeckstr. 1, Mainz 55131, Germany.; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Pokaż więcej
Źródło :
Science (New York, N.Y.) [Science] 2021 Jan 08; Vol. 371 (6525), pp. 145-153.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bystander Effect/*immunology
Encephalomyelitis, Autoimmune, Experimental/*therapy
Immunosuppression/*methods
Multiple Sclerosis/*therapy
Vaccines, Synthetic/*therapeutic use
Animals ; Antigen-Presenting Cells ; Autoantigens/genetics ; Inflammation/immunology ; Mice ; Mice, Inbred C57BL ; Pseudouridine/analogs & derivatives ; Pseudouridine/chemistry ; RNA, Messenger/adverse effects ; RNA, Messenger/chemistry ; RNA, Messenger/genetics ; T-Lymphocytes, Regulatory/immunology ; Vaccines, Synthetic/adverse effects
Czasopismo naukowe
Tytuł :
Recombinant vaccines for COVID-19.
Autorzy :
Yadav T; Department of Zoology, Jawaharlal Nehru Smriti Government Post Graduate College , Shujalpur, India.
Srivastava N; Department of Biotechnology, Meerut Institute of Engineering and Technology , Meerut, India.
Mishra G; Department of Biotechnology, Meerut Institute of Engineering and Technology , Meerut, India.
Dhama K; Division of Pathology, Indian Veterinary Research Institute (IVRI), Izatnagar , Bareilly, India.
Kumar S; Centre for Advanced Research (CFAR), Faculty of Medicine, King George's Medical University (KGMU) , Lucknow, India.
Puri B; Centre for Advanced Research (CFAR), Faculty of Medicine, King George's Medical University (KGMU) , Lucknow, India.
Saxena SK; Centre for Advanced Research (CFAR), Faculty of Medicine, King George's Medical University (KGMU) , Lucknow, India.
Pokaż więcej
Źródło :
Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2020 Dec 01; Vol. 16 (12), pp. 2905-2912. Date of Electronic Publication: 2020 Nov 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*prevention & control
COVID-19 Vaccines/*therapeutic use
Vaccines, Synthetic/*therapeutic use
COVID-19/genetics ; COVID-19/metabolism ; COVID-19 Vaccines/genetics ; COVID-19 Vaccines/metabolism ; Genetic Vectors/genetics ; Genetic Vectors/metabolism ; Genetic Vectors/therapeutic use ; Humans ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; Vaccines, Synthetic/metabolism
Czasopismo naukowe
Tytuł :
Evaluation of a recombinant tetanus toxin subunit vaccine.
Autorzy :
Liu FJ; Beijing Institute of Biotechnology, Beijing, 100071, China; Pharmaceutical College, Henan University, Kaifeng, 475001, China.
Shi DY; Beijing Institute of Biotechnology, Beijing, 100071, China.
Li ZY; Beijing Institute of Biotechnology, Beijing, 100071, China; Pharmaceutical College, Henan University, Kaifeng, 475001, China.
Lu JS; Beijing Institute of Biotechnology, Beijing, 100071, China.
Wang R; Beijing Institute of Biotechnology, Beijing, 100071, China.
Pang XB; Pharmaceutical College, Henan University, Kaifeng, 475001, China. Electronic address: .
Yang ZX; Beijing Institute of Biotechnology, Beijing, 100071, China. Electronic address: .
Yu YZ; Beijing Institute of Biotechnology, Beijing, 100071, China. Electronic address: .
Pokaż więcej
Źródło :
Toxicon : official journal of the International Society on Toxinology [Toxicon] 2020 Nov; Vol. 187, pp. 75-81. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Tetanus Toxin*
Vaccines, Synthetic*
Animals ; Antibodies, Neutralizing ; Gangliosides ; Humans ; Mice ; Mice, Inbred BALB C ; Tetanus ; Tetanus Toxoid ; Vaccines, Subunit
Czasopismo naukowe
Tytuł :
[Co-expression, purification and bioassay of three avian viral antigens].
Autorzy :
Zhang S; National Research Center for Veterinary Medicine, Luoyang 471000, Henan, China.
Wang M; National Research Center for Veterinary Medicine, Luoyang 471000, Henan, China.
Wang Y; National Research Center for Veterinary Medicine, Luoyang 471000, Henan, China.
Wu P; National Research Center for Veterinary Medicine, Luoyang 471000, Henan, China.
Pang W; National Research Center for Veterinary Medicine, Luoyang 471000, Henan, China.
Tian K; National Research Center for Veterinary Medicine, Luoyang 471000, Henan, China.
Pokaż więcej
Źródło :
Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2020 Oct 25; Vol. 36 (10), pp. 2066-2075.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Viral*/analysis
Antigens, Viral*/genetics
Infectious bursal disease virus*/immunology
Vaccines, Synthetic*/genetics
Vaccines, Synthetic*/immunology
Vaccines, Synthetic*/isolation & purification
Viral Vaccines*/genetics
Viral Vaccines*/immunology
Animals ; Biological Assay ; Chickens/immunology ; Escherichia coli/genetics ; Poultry Diseases ; Viral Structural Proteins/genetics ; Viral Structural Proteins/immunology
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies