- Tytuł:
- Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study.
- Autorzy:
-
Gudmundsdottir V; Department of Bio and Health Informatics, Technical University of Denmark, Kongens Lyngby, Denmark.
Pedersen HK; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Mazzoni G; Department of Bio and Health Informatics, Technical University of Denmark, Kongens Lyngby, Denmark.; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Allin KH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.
Artati A; Research Unit Molecular Endocrinology and Metabolism, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany.
Beulens JW; Amsterdam UMC, location VUmc, Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Banasik K; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Brorsson C; Department of Bio and Health Informatics, Technical University of Denmark, Kongens Lyngby, Denmark.
Cederberg H; Department of Endocrinology, Abdominal Center, Helsinki University Hospital, Helsinki, Finland.
Chabanova E; Department of Diagnostic Radiology, Copenhagen University Hospital Herlev Gentofte, Herlev, Denmark.
De Masi F; Department of Bio and Health Informatics, Technical University of Denmark, Kongens Lyngby, Denmark.
Elders PJ; Amsterdam UMC, location VUmc, Department of General Practice, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
Forgie I; Population Health & Genomics, School of Medicine, University of Dundee, Ninewells Hospital, Dundee, UK.
Giordano GN; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Clinical Research Centre, Lund University, Skåne University Hospital, Malmö, Sweden.
Grallert H; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.; Clinical Cooperation Group Type 2 Diabetes, Helmholtz Zentrum München and Ludwig-Maximilians Universität München, Munich, Germany.; Clinical Cooperation Group Nutrigenomics and Type 2 Diabetes, Helmholtz Zentrum München and Technische Universität München, Munich, Germany.
Gupta R; Department of Bio and Health Informatics, Technical University of Denmark, Kongens Lyngby, Denmark.; Novo Nordisk Research Centre Oxford, Oxford, UK.
Haid M; Research Unit Molecular Endocrinology and Metabolism, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany.
Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Hansen TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Cardiology and Endocrinology, Slagelse Hospital, Slagelse, Denmark.
Hattersley AT; The Institute of Clinical and Biological Sciences, University of Exeter College of Medicine and Health, University of Exeter, Exeter, UK.
Heggie A; Institute of Cellular Medicine (Diabetes), Newcastle University, Newcastle upon Tyne, UK.
Hong MG; Affinity Proteomics, Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Solna, Sweden.
Jones AG; The Institute of Clinical and Biological Sciences, University of Exeter College of Medicine and Health, University of Exeter, Exeter, UK.
Koivula R; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Clinical Research Centre, Lund University, Skåne University Hospital, Malmö, Sweden.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.
Kokkola T; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.
Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.
Løngreen P; Department of Bio and Health Informatics, Technical University of Denmark, Kongens Lyngby, Denmark.
Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Mari A; Institute of Neurosciences, National Research Council, Padova, Italy.
McDonald TJ; NIHR Exeter Clinical Research Facility, University of Exeter Medical School, Exeter, UK.
McEvoy D; Institute of Cellular Medicine (Diabetes), Newcastle University, Newcastle upon Tyne, UK.
Musholt PB; Sanofi, Diabetes Division, Research and Development, Frankfurt, Germany.
Pavo I; Eli Lilly Regional Operations GmbH, Vienna, Austria.
Prehn C; Research Unit Molecular Endocrinology and Metabolism, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany.
Ruetten H; Sanofi-Aventis Deutschland GmbH, R&D, Frankfurt am Main, Germany.
Ridderstråle M; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Clinical Research Centre, Lund University, Skåne University Hospital, Malmö, Sweden.; Novo Nordisk A/S, Søborg, Denmark.
Rutters F; Amsterdam UMC, location VUmc, Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
Sharma S; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
Slieker RC; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Epidemiology and Biostatistics, Amsterdam Public Health Institute, Amsterdam UMC, Amsterdam, The Netherlands.
Syed A; Department of Bio and Health Informatics, Technical University of Denmark, Kongens Lyngby, Denmark.
Tajes JF; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Thomas CE; Affinity Proteomics, Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Solna, Sweden.
Thomsen HS; Department of Diagnostic Radiology, Copenhagen University Hospital Herlev Gentofte, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.Vangipurapu J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.
Vestergaard H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Medicine, Bornholms Hospital, Rønne, Denmark.
Viñuela A; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.; Institute of Genetics and Genomics in Geneva (iGE3), University of Geneva, Geneva, Switzerland.; Swiss Institute of Bioinformatics, Geneva, Switzerland.
Wesolowska-Andersen A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Walker M; Institute of Cellular Medicine (Diabetes), Newcastle University, Newcastle upon Tyne, UK.
Adamski J; Research Unit Molecular Endocrinology and Metabolism, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany.; Lehrstuhl für Experimentelle Genetik, Technische Universität München, Freising-Weihenstephan, Germany.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Schwenk JM; Affinity Proteomics, Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Solna, Sweden.
McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
Pearson E; Population Health & Genomics, School of Medicine, University of Dundee, Ninewells Hospital, Dundee, UK.
Dermitzakis E; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.; Institute of Genetics and Genomics in Geneva (iGE3), University of Geneva, Geneva, Switzerland.; Swiss Institute of Bioinformatics, Geneva, Switzerland.
Franks PW; Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Clinical Research Centre, Lund University, Skåne University Hospital, Malmö, Sweden.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health & Clinical Medicine, Section for Medicine, Umeå University, Umeå, Sweden.
Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Brunak S; Department of Bio and Health Informatics, Technical University of Denmark, Kongens Lyngby, Denmark. .; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. . - Pokaż więcej
- Źródło:
- Genome medicine [Genome Med] 2020 Dec 01; Vol. 12 (1), pp. 109. Date of Electronic Publication: 2020 Dec 01.
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Phenotype*
Transcriptome*Diabetes Mellitus, Type 2 /*geneticsDiabetes Mellitus, Type 2 /*metabolism
Cohort Studies ; Gene Expression Regulation ; Genome-Wide Association Study ; Humans ; Insulin ; Insulin Resistance ; Leukocytes
Czasopismo naukowe