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Tytuł:
Neuron-specific deletion of VEGF or its receptor Flk-1 occludes the antidepressant-like effects of desipramine and fluoxetine in mice.
Autorzy:
Deyama S; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.; Laboratory of Molecular Pharmacology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Li XY; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
Duman RS; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
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Źródło:
Neuropsychopharmacology reports [Neuropsychopharmacol Rep] 2024 Mar; Vol. 44 (1), pp. 246-249. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article
MeSH Terms:
Fluoxetine*/pharmacology
Vascular Endothelial Growth Factor A*/metabolism
Vascular Endothelial Growth Factor A*/pharmacology
Mice ; Animals ; Desipramine/metabolism ; Desipramine/pharmacology ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Vascular Endothelial Growth Factor Receptor-2/pharmacology ; Antidepressive Agents/pharmacology ; Neurons/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells.
Autorzy:
Sarabipour S; Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America.
Kinghorn K; Curriculum in Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina, United States of America.; Department of Biology, University of North Carolina, Chapel Hill, North Carolina, United States of America.
Quigley KM; Department of Biology, University of North Carolina, Chapel Hill, North Carolina, United States of America.
Kovacs-Kasa A; Vascular Biology Center and Department of Medicine, Medical College of Georgia at Augusta University, Augusta, Georgia, United States of America.
Annex BH; Vascular Biology Center and Department of Medicine, Medical College of Georgia at Augusta University, Augusta, Georgia, United States of America.
Bautch VL; Curriculum in Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina, United States of America.; Department of Biology, University of North Carolina, Chapel Hill, North Carolina, United States of America.; McAllister Heart Institute, University of North Carolina, Chapel Hill, North Carolina, United States of America.
Mac Gabhann F; Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2024 Feb 07; Vol. 20 (2), pp. e1011798. Date of Electronic Publication: 2024 Feb 07 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Vascular Endothelial Growth Factor A*/metabolism
Vascular Endothelial Growth Factor Receptor-1*/metabolism
Humans ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Receptors, Vascular Endothelial Growth Factor/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Signal Transduction ; Phosphorylation ; Neuropilin-1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Endomucin selectively regulates vascular endothelial growth factor receptor-2 endocytosis through its interaction with AP2.
Autorzy:
Cano I; Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Present affiliation: Department of Molecular Medicine, Cornell University, Ithaca, NY, USA.
Wild M; Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Gupta U; Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Chaudhary S; Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Ng YSE; Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Present Affiliation: EyeBiotech, London, UK.
Saint-Geniez M; Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Present affiliation: Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
D'Amore PA; Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA, USA.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.
Hu Z; Schepens Eye Research Institute of Massachusetts Eye and Ear, Boston, MA, USA. zhengping_.; Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. zhengping_.
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Apr 11; Vol. 22 (1), pp. 225. Date of Electronic Publication: 2024 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Endothelial Cells*/metabolism
Vascular Endothelial Growth Factor A*/metabolism
Humans ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Sialomucins/metabolism ; Endocytosis ; Clathrin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Aflibercept Off-Target Effects in Diabetic Macular Edema: An In Silico Modeling Approach.
Autorzy:
Blanot M; Anaxomics Biotech S.L., 08007 Barcelona, Spain.
Casaroli-Marano RP; Department of Surgery (FMCS), Universitat de Barcelona, 08007 Barcelona, Spain.; Hospital Clínic de Barcelona (IDIBAPS), Universitat de Barcelona, 08007 Barcelona, Spain.
Mondéjar-Medrano J; Bayer Hispania S.L., 08970 Sant Joan Despí, Spain.
Sallén T; Bayer Hispania S.L., 08970 Sant Joan Despí, Spain.
Ramírez E; Anaxomics Biotech S.L., 08007 Barcelona, Spain.
Segú-Vergés C; Anaxomics Biotech S.L., 08007 Barcelona, Spain.; Research Programme on Biomedical Informatics (GRIB), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, 08002 Barcelona, Spain.
Artigas L; Anaxomics Biotech S.L., 08007 Barcelona, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 23; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 23.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetic Retinopathy*/drug therapy
Macular Edema*/drug therapy
Diabetes Mellitus*
Recombinant Fusion Proteins*
Receptors, Vascular Endothelial Growth Factor*
Humans ; Computer Simulation ; Vascular Endothelial Growth Factor A
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association analysis of Vascular Endothelial Growth Factor-A (VEGF-A) polymorphism in rheumatoid arthritis using computational approaches.
Autorzy:
Ahmed I; Atta-Ur-Rehman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), Islamabad, Pakistan.
John P; Faculty of Applied Biosciences, ASAB, NUST, Islamabad, Pakistan. .
Bhatti A; Faculty of Applied Biosciences, ASAB, NUST, Islamabad, Pakistan.
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 11; Vol. 13 (1), pp. 21957. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Arthritis, Rheumatoid*/genetics
Vascular Endothelial Growth Factor A*/genetics
Vascular Endothelial Growth Factor A*/metabolism
Humans ; Endothelial Cells/metabolism ; Neovascularization, Pathologic/metabolism ; Polymorphism, Single Nucleotide ; Vascular Endothelial Growth Factor Receptor-2/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biomechanical stimulation promotes blood vessel growth despite VEGFR-2 inhibition.
Autorzy:
Johnson BM; Department of Biomedical Engineering, University of Alabama at Birmingham, 1824 6th Avenue South, Wallace Tumor Institute, Room 630A, Birmingham, AL, 35294, USA.
Johnson AM; Department of Biomedical Engineering, University of Alabama at Birmingham, 1824 6th Avenue South, Wallace Tumor Institute, Room 630A, Birmingham, AL, 35294, USA.
Heim M; Department of Biomedical Engineering, University of Alabama at Birmingham, 1824 6th Avenue South, Wallace Tumor Institute, Room 630A, Birmingham, AL, 35294, USA.
Buckley M; Department of Biomedical Engineering, University of Alabama at Birmingham, 1824 6th Avenue South, Wallace Tumor Institute, Room 630A, Birmingham, AL, 35294, USA.
Mortimer B; Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35233, USA.
Berry JL; Department of Biomedical Engineering, University of Alabama at Birmingham, 1824 6th Avenue South, Wallace Tumor Institute, Room 630A, Birmingham, AL, 35294, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, 35233, USA.
Sewell-Loftin MK; Department of Biomedical Engineering, University of Alabama at Birmingham, 1824 6th Avenue South, Wallace Tumor Institute, Room 630A, Birmingham, AL, 35294, USA. .; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, 35233, USA. .
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Źródło:
BMC biology [BMC Biol] 2023 Dec 10; Vol. 21 (1), pp. 290. Date of Electronic Publication: 2023 Dec 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Neoplasms*/metabolism
Vascular Endothelial Growth Factor Receptor-2*/metabolism
Humans ; Endothelial Cells/metabolism ; Signal Transduction ; Tumor Microenvironment ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Thyroid hormone transport and metabolism are disturbed in the placental villi of miscarriage.
Autorzy:
Yu Z; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei, 230022, Anhui, China.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China.; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Feng X; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei, 230022, Anhui, China.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China.; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Lin Z; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei, 230022, Anhui, China.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China.; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Li X; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei, 230022, Anhui, China.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China.; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Su S; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei, 230022, Anhui, China.; Anhui Province Key Laboratory of Reproductive Health and Genetics, No.81 Meishan Road, Hefei, 230032, Anhui, China.; Biopreservation and Artificial Organs, Anhui Provincial Engineering Research Center, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China.
Cheng H; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei, 230022, Anhui, China.; Anhui Province Key Laboratory of Reproductive Health and Genetics, No.81 Meishan Road, Hefei, 230032, Anhui, China.; Biopreservation and Artificial Organs, Anhui Provincial Engineering Research Center, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China.
Yang Y; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei, 230022, Anhui, China. .; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China. .; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, No. 81 Meishan Road, Hefei, 230032, Anhui, China. .; Anhui Province Key Laboratory of Reproductive Health and Genetics, No.81 Meishan Road, Hefei, 230032, Anhui, China. .; Biopreservation and Artificial Organs, Anhui Provincial Engineering Research Center, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China. .
Wei Z; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei, 230022, Anhui, China. weizhaolian_.; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China. weizhaolian_.; Key Laboratory of Population Health Across Life Cycle (Anhui Medical University), Ministry of Education of the People's Republic of China, No. 81 Meishan Road, Hefei, 230032, Anhui, China. weizhaolian_.; Anhui Province Key Laboratory of Reproductive Health and Genetics, No.81 Meishan Road, Hefei, 230032, Anhui, China. weizhaolian_.; Biopreservation and Artificial Organs, Anhui Provincial Engineering Research Center, Anhui Medical University, No.81 Meishan Road, Hefei, 230032, Anhui, China. weizhaolian_.
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Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2023 Nov 15; Vol. 21 (1), pp. 108. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Vascular Endothelial Growth Factor Receptor-1*
Abortion, Spontaneous*/metabolism
Humans ; Pregnancy ; Female ; Vascular Endothelial Growth Factor A/metabolism ; Chorionic Villi/metabolism ; Cell Line, Tumor ; Placenta/metabolism ; Thyroid Hormones/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular Motifs in Vascular Morphogenesis: Vascular Endothelial Growth Factor A (VEGFA) as the Leading Promoter of Angiogenesis.
Autorzy:
Lungu CN; Departament of Functional and Morphological Science, Faculty of Medicine and Pharamacy, Dunarea de Jos University, 800010 Galati, Romania.
Mehedinti MC; Departament of Functional and Morphological Science, Faculty of Medicine and Pharamacy, Dunarea de Jos University, 800010 Galati, Romania.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 29; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 29.
Typ publikacji:
Journal Article
MeSH Terms:
Vascular Endothelial Growth Factor A*/genetics
Vascular Endothelial Growth Factor A*/metabolism
Peripheral Arterial Disease*/metabolism
Humans ; Angiotensin Receptor Antagonists ; Quality of Life ; Angiotensin-Converting Enzyme Inhibitors ; Vascular Endothelial Growth Factor Receptor-1/metabolism ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Morphogenesis/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Endocan Knockdown Down-Regulates the Expression of Angiogenesis-Associated Genes in Il-1ß Activated Chondrocytes.
Autorzy:
Scuruchi M; Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
Aliquò F; Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, 98122 Messina, Italy.
Avenoso A; Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, 98122 Messina, Italy.
Mandraffino G; Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
Vermiglio G; Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, 98122 Messina, Italy.
Minuti A; Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, 98122 Messina, Italy.
Campo S; Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, 98122 Messina, Italy.
Campo GM; Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
D'Ascola A; Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
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Źródło:
Biomolecules [Biomolecules] 2023 May 18; Vol. 13 (5). Date of Electronic Publication: 2023 May 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
NF-kappa B*/genetics
NF-kappa B*/metabolism
Vascular Endothelial Growth Factor Receptor-2*/metabolism
Humans ; Chondrocytes ; Inflammation/metabolism ; Matrix Metalloproteinase 13/metabolism ; Matrix Metalloproteinase 9/metabolism ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Novel Blood-Brain Barrier-Penetrating and Vascular-Targeting Chimeric Peptide Inhibits Glioma Angiogenesis.
Autorzy:
Lu L; Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-Based Medicine, Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Wang L; Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-Based Medicine, Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Zhao L; Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmacology, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Liao J; Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmacology, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Zhao C; Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-Based Medicine, Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Xu X; Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-Based Medicine, Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Wang F; Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-Based Medicine, Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Zhang X; Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmacology, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 15; Vol. 24 (10). Date of Electronic Publication: 2023 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Vascular Endothelial Growth Factor A*/metabolism
Glioma*/metabolism
Mice ; Animals ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Endothelial Cells/metabolism ; Zebrafish/metabolism ; Blood-Brain Barrier/metabolism ; Mice, Nude ; Peptides/chemistry ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Pathologic/metabolism ; Angiogenesis Inhibitors/therapeutic use ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Do Aging and Parity Affect VEGF-A/VEGFR Content and Signaling in the Ovary?-A Mouse Model Study.
Autorzy:
Di Nisio V; Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynecology, Karolinska Institutet and Karolinska University Hospital, 14186 Huddinge, Sweden.
Rossi G; Department of Life, Health and Environmental Sciences, University of L'Aquila, Via Vetoio, 67100 L'Aquila, Italy.
Chiominto A; Department of Pathology, San Salvatore Hospital, 67100 L'Aquila, Italy.
Pompili E; Department of Pathology, San Salvatore Hospital, 67100 L'Aquila, Italy.
Cecconi S; Department of Life, Health and Environmental Sciences, University of L'Aquila, Via Vetoio, 67100 L'Aquila, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 07; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Ovary*/metabolism
Vascular Endothelial Growth Factor A*/metabolism
Animals ; Female ; Mice ; Pregnancy ; Aging ; Parity ; Signal Transduction ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Vascular Endothelial Growth Factor Receptor-1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Endothelial Glycocalyx as a Target of Excess Soluble Fms-like Tyrosine Kinase-1.
Autorzy:
Schulz A; Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany.
Drost CC; Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany.
Hesse B; Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany.
Beul K; Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany.
Boeckel GR; Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany.
Lukasz A; Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany.
Pavenstädt H; Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany.
Brand M; Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany.
Di Marco GS; Department of Internal Medicine D, University Hospital Münster, 48149 Münster, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 11; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 11.
Typ publikacji:
Journal Article
MeSH Terms:
Vascular Endothelial Growth Factor Receptor-1*/metabolism
Pre-Eclampsia*/metabolism
Humans ; Animals ; Mice ; Female ; Vascular Endothelial Growth Factor A/metabolism ; Glycocalyx/metabolism ; Endothelium/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cutaneous vascular structure and perfusion in patients with chronic plaque psoriasis.
Autorzy:
Luengas-Martinez A; Centre for Dermatology Research and Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
Kamaly-Asl A; Centre for Dermatology Research and Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
Chaudhry IH; Department of Pathology, Manchester Royal Infirmary, Manchester, UK.
Brenchley PEC; Department of Renal Research, The University of Manchester, Manchester Royal Infirmary, Manchester, UK.
Young HS; Centre for Dermatology Research and Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
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Źródło:
Clinical and experimental dermatology [Clin Exp Dermatol] 2023 Mar 01; Vol. 48 (3), pp. 181-187.
Typ publikacji:
Journal Article
MeSH Terms:
Vascular Endothelial Growth Factor A*/metabolism
Psoriasis*/pathology
Humans ; Vascular Endothelial Growth Factor D/metabolism ; Leukocytes, Mononuclear/metabolism ; Skin/pathology ; Perfusion
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Polymorphic Variants of Genes Encoding Angiogenesis-Related Factors in Infertile Women with Recurrent Implantation Failure.
Autorzy:
Mrozikiewicz AE; Department of Obstetrics and Women's Diseases, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.; Chair and Department of Cell Biology, Poznan University of Medical Sciences, Rokietnicka 5D, 60-806 Poznan, Poland.
Kurzawińska G; Division of Perinatology and Womens Diseases, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.
Ożarowski M; Department of Biotechnology, Institute of Natural Fibres and Medicinal Plants-National Research Institute, Wojska Polskiego 71B, 60-630 Poznan, Poland.
Walczak M; Institute of Human Genetics, Polish Academy of Sciences, Strzeszyńska 32, 60-479 Poznan, Poland.
Ożegowska K; Department of Infertility and Reproductive Endocrinology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.
Jędrzejczak P; Chair and Department of Cell Biology, Poznan University of Medical Sciences, Rokietnicka 5D, 60-806 Poznan, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 21; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Infertility, Female*
Vascular Endothelial Growth Factor A*/genetics
Female ; Humans ; Pregnancy ; Case-Control Studies ; Genotype ; Placenta ; Polymorphism, Single Nucleotide ; Vascular Endothelial Growth Factor Receptor-2/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Elucidating activation and deactivation dynamics of VEGFR-2 transmembrane domain with coarse-grained molecular dynamics simulations.
Autorzy:
Go YJ; Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.
Kalathingal M; Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.; Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Rhee YM; Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.
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Źródło:
PloS one [PLoS One] 2023 Feb 16; Vol. 18 (2), pp. e0281781. Date of Electronic Publication: 2023 Feb 16 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Molecular Dynamics Simulation*
Vascular Endothelial Growth Factor Receptor-2*/metabolism
Ligands ; Vascular Endothelial Growth Factor A ; Protein Domains
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Conjugated Bile Acids Promote Lymphangiogenesis by Modulation of the Reactive Oxygen Species-p90RSK-Vascular Endothelial Growth Factor Receptor 3 Pathway.
Autorzy:
Banerjee P; Department of Medical Physiology, Texas A&M Health Science Center, Bryan, TX 77807, USA.
Kumaravel S; Department of Medical Physiology, Texas A&M Health Science Center, Bryan, TX 77807, USA.
Roy S; Department of Medical Physiology, Texas A&M Health Science Center, Bryan, TX 77807, USA.
Gaddam N; Department of Medical Physiology, Texas A&M Health Science Center, Bryan, TX 77807, USA.
Odeh J; Department of Medical Physiology, Texas A&M Health Science Center, Bryan, TX 77807, USA.
Bayless KJ; Department of Molecular and Cellular Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.
Glaser S; Department of Medical Physiology, Texas A&M Health Science Center, Bryan, TX 77807, USA.
Chakraborty S; Department of Medical Physiology, Texas A&M Health Science Center, Bryan, TX 77807, USA.
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Źródło:
Cells [Cells] 2023 Feb 06; Vol. 12 (4). Date of Electronic Publication: 2023 Feb 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lymphangiogenesis*
Vascular Endothelial Growth Factor A*/metabolism
Mice ; Animals ; Humans ; Reactive Oxygen Species/metabolism ; Endothelial Cells/metabolism ; Vascular Endothelial Growth Factor Receptor-3/metabolism ; Steroids/metabolism ; Bile Acids and Salts/metabolism
Czasopismo naukowe
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Tytuł:
Vascular Endothelial Growth Factor and Its Soluble Receptor in Systemic Lupus Erythematosus Patients.
Autorzy:
Gómez-Bernal F; Division of Central Laboratory, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Fernández-Cladera Y; Division of Central Laboratory, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Quevedo-Abeledo JC; Division of Rheumatology, Hospital Doctor Negrín, 35010 Las Palmas de Gran Canaria, Spain.
García-González M; Division of Rheumatology, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
González-Rivero AF; Division of Central Laboratory, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
de Vera-González A; Division of Central Laboratory, Hospital Universitario de Canarias, 38320 Tenerife, Spain.
Martín-González C; Division of Internal Medicine, Hospital Universitario de Canarias, 38320 Tenerife, Spain.; Department of Internal Medicine, University of La Laguna (ULL), 38200 Tenerife, Spain.
González-Gay MÁ; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Hospital Universitario Marqués de Valdecilla, IDIVAL, 39011 Santander, Spain.; Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, 39011 Santander, Spain.; Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa.
Ferraz-Amaro I; Division of Rheumatology, Hospital Universitario de Canarias, 38320 Tenerife, Spain.; Department of Internal Medicine, University of La Laguna (ULL), 38200 Tenerife, Spain.
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Źródło:
Biomolecules [Biomolecules] 2022 Dec 15; Vol. 12 (12). Date of Electronic Publication: 2022 Dec 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lupus Erythematosus, Systemic*/blood
Lupus Erythematosus, Systemic*/metabolism
Vascular Endothelial Growth Factor A*/blood
Vascular Endothelial Growth Factor A*/metabolism
Humans ; Neovascularization, Pathologic ; Vascular Endothelial Growth Factor Receptor-1/blood ; Vascular Endothelial Growth Factor Receptor-1/metabolism ; Vascular Endothelial Growth Factor Receptor-2/blood ; Vascular Endothelial Growth Factor Receptor-2/metabolism
Czasopismo naukowe
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Tytuł:
Deglycosylation Increases the Aggregation and Angiogenic Properties of Mutant Tissue Inhibitor of Metalloproteinase 3 Protein: Implications for Sorsby Fundus Dystrophy.
Autorzy:
Qi JH; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Anand-Apte B; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 17; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Tissue Inhibitor of Metalloproteinase-3*/genetics
Tissue Inhibitor of Metalloproteinase-3*/metabolism
Vascular Endothelial Growth Factor Receptor-2*/genetics
Vascular Endothelial Growth Factor Receptor-2*/metabolism
Macular Degeneration*/genetics
Macular Degeneration*/metabolism
Humans ; Endothelial Cells/metabolism ; Matrix Metalloproteinases/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factors/metabolism ; Glycosylation ; Protein Aggregates/genetics ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism
SCR Disease Name:
Fundus Dystrophy, Pseudoinflammatory, Of Sorsby
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of aflibercept and bevacizumab on cell viability, cell metabolism and inflammation in hypoxic human Müller cells.
Autorzy:
Matsuda M; Laboratory of Investigation in Ophthalmology (LIM-33), Division of Ophthalmology, School of Medicine, University of São Paulo, São Paulo, SP, Brazil.; Department of Cell & Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
da Silva RA; Department of Cell & Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
Roda VMP; Department of Cell & Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
Marquezini MV; Laboratory of Investigation in Ophthalmology (LIM-33), Division of Ophthalmology, School of Medicine, University of São Paulo, São Paulo, SP, Brazil.
Monteiro MLR; Laboratory of Investigation in Ophthalmology (LIM-33), Division of Ophthalmology, School of Medicine, University of São Paulo, São Paulo, SP, Brazil.
Hamassaki DE; Department of Cell & Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
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Źródło:
PloS one [PLoS One] 2024 Mar 27; Vol. 19 (3), pp. e0300370. Date of Electronic Publication: 2024 Mar 27 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Vascular Endothelial Growth Factor A*/metabolism
Ependymoglial Cells*/metabolism
Recombinant Fusion Proteins*
Receptors, Vascular Endothelial Growth Factor*
Humans ; Bevacizumab/pharmacology ; Bevacizumab/metabolism ; Cell Survival ; Becaplermin/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Interleukin-8/metabolism ; Interleukin-6/metabolism ; Vascular Endothelial Growth Factors/metabolism ; Cytokines/metabolism ; Hypoxia/metabolism ; Neovascularization, Pathologic/pathology ; Inflammation/pathology
Czasopismo naukowe
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Tytuł:
The VEGF/VEGFR Axis Revisited: Implications for Cancer Therapy.
Autorzy:
Mabeta P; Department of Physiology, Faculty of Health Sciences, University of Pretoria, Gezina 0031, South Africa.
Steenkamp V; Department of Pharmacology, Faculty of Health Sciences, University of Pretoria, Gezina 0031, South Africa.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 09; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Vascular Endothelial Growth Factor Receptor-1*
Neoplasms*/drug therapy
Neoplasms*/genetics
Neoplasms*/metabolism
Humans ; Vascular Endothelial Growth Factor A/metabolism ; Receptors, Vascular Endothelial Growth Factor/metabolism ; Vascular Endothelial Growth Factors ; Vascular Endothelial Growth Factor Receptor-2/genetics ; Tumor Microenvironment/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 43334

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