Autor: "Veidal SS" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: A novel marker for assessment of liver matrix remodeling: An enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M).
Autorzy:: Leeming, DJ.
He, Y.
Veidal, SS.
Nguyen, QHT.
Larsen, DV.
Koizumi, M.
Segovia-Silvestre, T.
Zhang, C.
Zheng, Q.
Sun, S.
Cao, Y.
Barkholt, V.
Hägglund, P.
Bay-Jensen, AC.
Qvist, P.
Karsdal, MA.; Pokaż więcej
Temat:: BIOMARKERS
LIVER
BIOLOGICAL assay
COLLAGEN
EPITOPES
PROTEOLYTIC enzymes
BONE metastasis
BREAST cancer
Źródło:: Biomarkers; Nov2011, Vol. 16 Issue 7, p616-628, 13p, 1 Color Photograph, 1 Diagram, 3 Charts, 5 Graphs

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Skocz do pozycji: 2.

Tytuł:: Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH.
Autorzy:: Møllerhøj MB; Gubra, Hørsholm, Denmark.
Veidal SS; Gubra, Hørsholm, Denmark.
Thrane KT; Gubra, Hørsholm, Denmark.
Oró D; Gubra, Hørsholm, Denmark.
Overgaard A; Gubra, Hørsholm, Denmark.
Salinas CG; Gubra, Hørsholm, Denmark.
Madsen MR; Gubra, Hørsholm, Denmark.
Pfisterer L; Boehringer-Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
Vyberg M; Center for RNA Medicine, Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark.
Simon E; Boehringer-Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
Broermann A; Boehringer-Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
Vrang N; Gubra, Hørsholm, Denmark.
Jelsing J; Gubra, Hørsholm, Denmark.
Feigh M; Gubra, Hørsholm, Denmark.
Hansen HH; Gubra, Hørsholm, Denmark.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2022 May; Vol. 15 (5), pp. 1167-1186. Date of Electronic Publication: 2022 Feb 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Non-alcoholic Fatty Liver Disease*/drug therapy
Non-alcoholic Fatty Liver Disease*/etiology
Animals ; Benzothiazoles ; Biopsy ; Diet ; Disease Models, Animal ; Disease Progression ; Glucagon-Like Peptides ; Humans ; Liver ; Liver Cirrhosis/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Obesity/complications ; Obesity/drug therapy ; Obesity/metabolism ; Sulfonamides

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Skocz do pozycji: 3.

Tytuł:: Elafibranor and liraglutide improve differentially liver health and metabolism in a mouse model of non-alcoholic steatohepatitis.
Autorzy:: Perakakis N; Department of Medicine, Boston VA Healthcare System and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Stefanakis K; Department of Medicine, Boston VA Healthcare System and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Feigh M; Gubra, Hørsholm, Denmark.
Veidal SS; Gubra, Hørsholm, Denmark.
Mantzoros CS; Department of Medicine, Boston VA Healthcare System and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Pokaż więcej
Źródło:: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2021 Aug; Vol. 41 (8), pp. 1853-1866. Date of Electronic Publication: 2021 Apr 21.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Non-alcoholic Fatty Liver Disease*/drug therapy
Animals ; Chalcones ; Diet, High-Fat ; Liraglutide/pharmacology ; Liver ; Male ; Mice ; Mice, Inbred C57BL ; Propionates

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Skocz do pozycji: 4.

Tytuł:: Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASH.
Autorzy:: Perakakis N; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA.
Chrysafi P; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA.
Feigh M; Gubra, Hørsholm Kongevej 11, B, 2970 Hørsholm, Denmark.
Veidal SS; Gubra, Hørsholm Kongevej 11, B, 2970 Hørsholm, Denmark.
Mantzoros CS; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA.; Department of Medicine, Boston VA Healthcare System, Harvard Medical School, Boston, MA 02115, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 13; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 13.
Typ publikacji:: Journal Article
MeSH Terms:: Benzhydryl Compounds/*therapeutic use
Glucosides/*therapeutic use
Liver/*metabolism
Non-alcoholic Fatty Liver Disease/*drug therapy
Non-alcoholic Fatty Liver Disease/*metabolism
Animals ; Antigens, CD/metabolism ; Benzhydryl Compounds/pharmacology ; Biopsy ; Body Composition/drug effects ; Body Weight/drug effects ; Disease Models, Animal ; Glucose/metabolism ; Glucosides/pharmacology ; Homeostasis/drug effects ; Insulin Resistance ; Lactosylceramides/metabolism ; Lipidomics ; Liver/drug effects ; Liver/pathology ; Mice, Inbred C57BL ; Mice, Obese ; Non-alcoholic Fatty Liver Disease/pathology ; Triglycerides/metabolism

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Skocz do pozycji: 5.

Tytuł:: Activation of thyroid hormone receptor-β improved disease activity and metabolism independent of body weight in a mouse model of non-alcoholic steatohepatitis and fibrosis.
Autorzy:: Kannt A; Diabetes Research, Sanofi Research and Development, Frankfurt, Germany.; Institute of Pharmacology, Goethe University, Frankfurt, Germany.; Department of Drug Discovery, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt, Germany.
Wohlfart P; Diabetes Research, Sanofi Research and Development, Frankfurt, Germany.
Madsen AN; NASH CRO, Gubra, Hørsholm, Denmark.
Veidal SS; NASH CRO, Gubra, Hørsholm, Denmark.
Feigh M; NASH CRO, Gubra, Hørsholm, Denmark.
Schmoll D; Diabetes Research, Sanofi Research and Development, Frankfurt, Germany.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2021 Jun; Vol. 178 (12), pp. 2412-2423. Date of Electronic Publication: 2021 Apr 06.
Typ publikacji:: Journal Article
MeSH Terms:: Non-alcoholic Fatty Liver Disease*/drug therapy
Non-alcoholic Fatty Liver Disease*/pathology
Animals ; Diet, High-Fat ; Disease Models, Animal ; Humans ; Liver/pathology ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/pathology ; Mice ; Mice, Inbred C57BL ; Obesity/pathology ; Thyroid Hormone Receptors beta/genetics

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Skocz do pozycji: 6.

Tytuł:: Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis.
Autorzy:: Hansen HH; Gubra, DK-2970, Hørsholm, Denmark. .
Ægidius HM; Gubra, DK-2970, Hørsholm, Denmark.
Oró D; Gubra, DK-2970, Hørsholm, Denmark.
Evers SS; Gubra, DK-2970, Hørsholm, Denmark.
Heebøll S; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Eriksen PL; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Thomsen KL; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Bengtsson A; Gubra, DK-2970, Hørsholm, Denmark.
Veidal SS; Gubra, DK-2970, Hørsholm, Denmark.
Feigh M; Gubra, DK-2970, Hørsholm, Denmark.
Suppli MP; Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
Knop FK; Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Grønbæk H; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Miranda D; Gilead Sciences, Foster City, CA, USA.
Trevaskis JL; Gilead Sciences, Foster City, CA, USA.
Vrang N; Gubra, DK-2970, Hørsholm, Denmark.
Jelsing J; Gubra, DK-2970, Hørsholm, Denmark.
Rigbolt KTG; Gubra, DK-2970, Hørsholm, Denmark.; Pokaż więcej
Źródło:: BMC gastroenterology [BMC Gastroenterol] 2020 Jul 06; Vol. 20 (1), pp. 210. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji:: Journal Article
MeSH Terms:: Non-alcoholic Fatty Liver Disease*
Animals ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Humans ; Liver ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Obesity/complications

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Skocz do pozycji: 7.

Tytuł:: Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis.
Autorzy:: Ægidius HM; Gubra, Hørsholm Kongevej 11B, Hørsholm, Denmark.
Veidal SS; Gubra, Hørsholm Kongevej 11B, Hørsholm, Denmark.
Feigh M; Gubra, Hørsholm Kongevej 11B, Hørsholm, Denmark.
Hallenborg P; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Puglia M; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
Vrang N; Gubra, Hørsholm Kongevej 11B, Hørsholm, Denmark.
Jelsing J; Gubra, Hørsholm Kongevej 11B, Hørsholm, Denmark.
Kornum BR; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark.
Blagoev B; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Rigbolt KTG; Gubra, Hørsholm Kongevej 11B, Hørsholm, Denmark. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Jan 24; Vol. 10 (1), pp. 1148. Date of Electronic Publication: 2020 Jan 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Transcriptome*
Diet, High-Fat/*adverse effects
Liver/*metabolism
Non-alcoholic Fatty Liver Disease/*etiology
Obesity/*etiology
Proteomics/*methods
Animals ; Chromatography, Liquid ; Disease Models, Animal ; Male ; Mice ; Mice, Inbred C57BL ; Non-alcoholic Fatty Liver Disease/genetics ; Non-alcoholic Fatty Liver Disease/metabolism ; Obesity/genetics ; RNA/genetics ; RNA/isolation & purification ; Sequence Alignment ; Sequence Analysis, RNA ; Single-Cell Analysis ; Tandem Mass Spectrometry

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Skocz do pozycji: 8.

Tytuł:: Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH.
Autorzy:: Baandrup Kristiansen MN; Gubra Aps, Hoersholm, Denmark.; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Veidal SS; Gubra Aps, Hoersholm, Denmark.
Christoffersen C; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Bispebjerg Hospital and Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Feigh M; Gubra Aps, Hoersholm, Denmark.
Vrang N; Gubra Aps, Hoersholm, Denmark.
Roth JD; Intercept Pharmaceuticals, San Diego, California, USA.
Erickson M; Intercept Pharmaceuticals, San Diego, California, USA.
Adorini L; Intercept Pharmaceuticals, San Diego, California, USA.
Jelsing J; Gubra Aps, Hoersholm, Denmark. .; Pokaż więcej
Źródło:: BMC gastroenterology [BMC Gastroenterol] 2019 Dec 28; Vol. 19 (1), pp. 228. Date of Electronic Publication: 2019 Dec 28.
Typ publikacji:: Journal Article
MeSH Terms:: Liver/*drug effects
Liver/*pathology
Non-alcoholic Fatty Liver Disease/*drug therapy
Non-alcoholic Fatty Liver Disease/*pathology
Obesity/*complications
Animals ; Bile Acids and Salts/therapeutic use ; Biopsy ; Body Weight/drug effects ; Chalcones/therapeutic use ; Collagen Type I/analysis ; Diet, High-Fat ; Galectin 3/analysis ; Islet Amyloid Polypeptide/administration & dosage ; Leptin/deficiency ; Lipids/analysis ; Liraglutide/therapeutic use ; Liver/chemistry ; Liver Cirrhosis/pathology ; Male ; Mice ; Mice, Obese ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/metabolism ; Organ Size/drug effects ; PPAR alpha/agonists ; PPAR delta/agonists ; Propionates/therapeutic use ; Reproducibility of Results

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Skocz do pozycji: 9.

Tytuł:: Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion.
Autorzy:: Eriksen PL; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Vilstrup H; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Rigbolt K; Gubra, Hørsholm, Denmark.
Suppli MP; Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
Sørensen M; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Heebøll S; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Veidal SS; Gubra, Hørsholm, Denmark.
Knop FK; Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark.
Thomsen KL; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.; Pokaż więcej
Źródło:: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2019 Nov; Vol. 39 (11), pp. 2094-2101. Date of Electronic Publication: 2019 Sep 05.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Enzymologic*
Carbamoyl-Phosphate Synthase (Ammonia)/*genetics
Non-alcoholic Fatty Liver Disease/*genetics
Urea/*metabolism
Adult ; Ammonia/metabolism ; Case-Control Studies ; Female ; Glutamate-Ammonia Ligase/genetics ; Hepatocytes/metabolism ; Humans ; Liver/metabolism ; Liver/pathology ; Male ; Middle Aged ; Non-alcoholic Fatty Liver Disease/physiopathology ; Obesity/metabolism ; Transcriptome

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Skocz do pozycji: 10.

Tytuł:: Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH.
Autorzy:: Roth JD; Intercept Pharmaceuticals, San Diego, CA, USA.
Veidal SS; Gubra, Hørsholm, Denmark.
Fensholdt LKD; Gubra, Hørsholm, Denmark.
Rigbolt KTG; Gubra, Hørsholm, Denmark.
Papazyan R; Intercept Pharmaceuticals, San Diego, CA, USA.
Nielsen JC; Gubra, Hørsholm, Denmark.
Feigh M; Gubra, Hørsholm, Denmark.
Vrang N; Gubra, Hørsholm, Denmark.
Young M; Intercept Pharmaceuticals, San Diego, CA, USA.
Jelsing J; Gubra, Hørsholm, Denmark.
Adorini L; Intercept Pharmaceuticals, San Diego, CA, USA.
Hansen HH; Gubra, Hørsholm, Denmark. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Jun 21; Vol. 9 (1), pp. 9046. Date of Electronic Publication: 2019 Jun 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chalcones/*therapeutic use
Chenodeoxycholic Acid/*analogs & derivatives
Liver Cirrhosis/*drug therapy
Propionates/*therapeutic use
Animals ; Biopsy ; Chenodeoxycholic Acid/therapeutic use ; Disease Models, Animal ; Liver Cirrhosis/pathology ; Mice ; PPAR alpha/metabolism ; Proof of Concept Study ; Transcription, Genetic

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Skocz do pozycji: 11.

Tytuł:: Plasma Pro-C3 (N-terminal type III collagen propeptide) predicts fibrosis progression in patients with chronic hepatitis C.
Autorzy:: Nielsen MJ; Nordic Bioscience A/S, Herlev, Denmark; Faculty of Health Science, University of Southern Denmark, Odense, Denmark.
Veidal SS
Karsdal MA
Ørsnes-Leeming DJ
Vainer B
Gardner SD
Hamatake R
Goodman ZD
Schuppan D
Patel K; Pokaż więcej
Źródło:: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2015 Feb; Vol. 35 (2), pp. 429-37. Date of Electronic Publication: 2014 Oct 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Biomarkers/*blood
Collagen Type III/*blood
Hepatitis C, Chronic/*physiopathology
Liver Cirrhosis/*diagnosis
Cohort Studies ; Disease Progression ; Enzyme-Linked Immunosorbent Assay ; Hepatitis C, Chronic/blood ; Hepatitis C, Chronic/complications ; Humans ; Liver Cirrhosis/etiology ; Multivariate Analysis ; Predictive Value of Tests

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Skocz do pozycji: 12.

Tytuł:: Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases.
Autorzy:: Genovese F; Nordic Bioscience A/S, Herlev Hovedgade 207, Herlev, DK-2730, Denmark. .
Barascuk N
Larsen L
Larsen MR
Nawrocki A
Li Y
Zheng Q
Wang J
Veidal SS
Leeming DJ
Karsdal MA; Pokaż więcej
Źródło:: Fibrogenesis & tissue repair [Fibrogenesis Tissue Repair] 2013 May 01; Vol. 6 (1), pp. 9. Date of Electronic Publication: 2013 May 01.
Typ publikacji:: Journal Article

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Skocz do pozycji: 13.

Tytuł:: Phosphodiesterase inhibition mediates matrix metalloproteinase activity and the level of collagen degradation fragments in a liver fibrosis ex vivo rat model.
Autorzy:: Veidal SS; Nordic Bioscience A/S, Herlev Hovedgade 207, 2730, Herlev, Denmark.
Nielsen MJ
Leeming DJ
Karsdal MA; Pokaż więcej
Źródło:: BMC research notes [BMC Res Notes] 2012 Dec 18; Vol. 5 (1), pp. 686. Date of Electronic Publication: 2012 Dec 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: 1-Methyl-3-isobutylxanthine/*pharmacology
Collagen Type III/*metabolism
Liver Cirrhosis/*metabolism
Matrix Metalloproteinase 9/*metabolism
Phosphodiesterase Inhibitors/*pharmacology
Phosphoric Diester Hydrolases/*metabolism
Animals ; Cell Survival/physiology ; Collagen Type III/blood ; Cyclic AMP/metabolism ; Electrophoresis, Polyacrylamide Gel ; Immunohistochemistry ; Liver Cirrhosis/enzymology ; Liver Cirrhosis/pathology ; Male ; Rats ; Rats, Sprague-Dawley

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Skocz do pozycji: 14.

Tytuł:: Enzyme-linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S): A marker related to the extracellular matrix remodeling during liver fibrogenesis.
Autorzy:: Leeming DJ; Nordic Bioscience, Fibrosis Biology and Biomarkers, Herlev, Denmark Nordic Bioscience Beijing, Beijing, China Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Nielsen MJ
Dai Y
Veidal SS
Vassiliadis E
Zhang C
He Y
Vainer B
Zheng Q
Karsdal MA; Pokaż więcej
Źródło:: Hepatology research : the official journal of the Japan Society of Hepatology [Hepatol Res] 2012 May; Vol. 42 (5), pp. 482-93. Date of Electronic Publication: 2012 Jan 05.
Typ publikacji:: Journal Article

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Skocz do pozycji: 15.

Tytuł:: Circulating levels of a collagen type v propeptide fragment in a carbon tetrachloride reversible model of liver fibrosis.
Autorzy:: Vassiliadis E; Nordic Bioscience A/S, Herlev, Denmark. ; University of Southern Denmark, Odense, Denmark.
Veidal SS
Hansen C
Karsdal MA
Leeming DJ; Pokaż więcej
Źródło:: Biomarker insights [Biomark Insights] 2012; Vol. 7, pp. 159-66. Date of Electronic Publication: 2012 Dec 17.
Typ publikacji:: Journal Article

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Skocz do pozycji: 16.

Tytuł:: A novel marker for assessment of liver matrix remodeling: an enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M).
Autorzy:: Leeming Dj; Nordic Bioscience, Fibrosis Biology and Biomarkers , Herlev , Denmark.
He Y
Veidal S
Nguyen Q
Larsen D
Koizumi M
Segovia-Silvestre T
Zhang C
Zheng Q
Sun S
Cao Y
Barkholt V
Hägglund P
Bay-Jensen A
Qvist P
Karsdal M; Pokaż więcej
Źródło:: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2011 Nov; Vol. 16 (7), pp. 616-28. Date of Electronic Publication: 2011 Oct 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Biomarkers/*analysis
Collagen Type I/*analysis
Enzyme-Linked Immunosorbent Assay/*methods
Extracellular Matrix/*metabolism
Liver/*metabolism
Matrix Metalloproteinases/*metabolism
Animals ; Bile Ducts/surgery ; Bone Neoplasms/diagnosis ; Bone Neoplasms/metabolism ; Bone Neoplasms/secondary ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Carbon Tetrachloride/toxicity ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Epitopes/analysis ; Female ; Humans ; Ligation/adverse effects ; Liver/drug effects ; Liver/pathology ; Liver Cirrhosis, Experimental/diagnosis ; Liver Cirrhosis, Experimental/etiology ; Liver Cirrhosis, Experimental/metabolism ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Male ; Mice ; Mice, Inbred BALB C ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar ; Sensitivity and Specificity

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Skocz do pozycji: 17.

Tytuł:: Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis.
Autorzy:: Veidal SS; Nordic Bioscience A/S, Herlev Hovedgade 207, DK-2730 Herlev, Denmark. .
Karsdal MA
Nawrocki A
Larsen MR
Dai Y
Zheng Q
Hägglund P
Vainer B
Skjøt-Arkil H
Leeming DJ; Pokaż więcej
Źródło:: Fibrogenesis & tissue repair [Fibrogenesis Tissue Repair] 2011 Oct 05; Vol. 4, pp. 22. Date of Electronic Publication: 2011 Oct 05.
Typ publikacji:: Journal Article

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Skocz do pozycji: 18.

Tytuł:: Immunological detection of the type V collagen propeptide fragment, PVCP-1230, in connective tissue remodeling associated with liver fibrosis.
Autorzy:: Vassiliadis E; Nordic Bioscience A/S, Herlev, Denmark. />Veidal SS
Simonsen H
Larsen DV
Vainer B
Chen X
Zheng Q
Karsdal MA
Leeming DJ; Pokaż więcej
Źródło:: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2011 Aug; Vol. 16 (5), pp. 426-33. Date of Electronic Publication: 2011 May 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Collagen Type V/*chemistry
Connective Tissue/*physiopathology
Liver Cirrhosis/*metabolism
Peptide Fragments/*analysis
Animals ; Collagen Type V/metabolism ; Enzyme-Linked Immunosorbent Assay ; Liver Cirrhosis/physiopathology ; Male ; Mice ; Mice, Inbred BALB C ; Peptide Fragments/metabolism ; Rats ; Rats, Wistar ; Reproducibility of Results

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Skocz do pozycji: 19.

Tytuł:: Measurement of CO3-610, a potential liver biomarker derived from matrix metalloproteinase-9 degradation of collagen type iii, in a rat model of reversible carbon-tetrachloride-induced fibrosis.
Autorzy:: Vassiliadis E; Nordic Bioscience, Herlev, Denmark.
Larsen DV
Clausen RE
Veidal SS
Barascuk N
Larsen L
Simonsen H
Silvestre TS
Hansen C
Overgaard T
Leeming DJ
Karsdal MA; Pokaż więcej
Źródło:: Biomarker insights [Biomark Insights] 2011 Mar 24; Vol. 6, pp. 49-58. Date of Electronic Publication: 2011 Mar 24.
Typ publikacji:: Journal Article

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Skocz do pozycji: 20.

Tytuł:: MMP mediated degradation of type VI collagen is highly associated with liver fibrosis--identification and validation of a novel biochemical marker assay.
Autorzy:: Veidal SS; Nordic Bioscience A/S, Herlev, Denmark. />Karsdal MA
Vassiliadis E
Nawrocki A
Larsen MR
Nguyen QH
Hägglund P
Luo Y
Zheng Q
Vainer B
Leeming DJ; Pokaż więcej
Źródło:: PloS one [PLoS One] 2011; Vol. 6 (9), pp. e24753. Date of Electronic Publication: 2011 Sep 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:: Enzyme-Linked Immunosorbent Assay*
Collagen Type VI/*metabolism
Liver Cirrhosis/*metabolism
Matrix Metalloproteinase 2/*metabolism
Matrix Metalloproteinase 9/*metabolism
Animals ; Biomarkers/analysis ; Carbon Tetrachloride/toxicity ; Female ; Humans ; Liver Cirrhosis/chemically induced ; Male ; Mass Spectrometry ; Mice ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar

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