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    Wyświetlanie 1-4 z 4
    Tytuł:
    Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor.
    Autorzy:
    Anchoori RK; Department of Oncology, Johns Hopkins University, Baltimore, MD, United States of America.; Department of Pathology, Johns Hopkins University, Baltimore, MD, United States of America.; Up Therapeutics LLC, Frederick, MD, United States of America.
    Anchoori V; Up Therapeutics LLC, Frederick, MD, United States of America.; SV Chem Biotech, Edmonton, AB, Canada.
    Lam B; Department of Pathology, Johns Hopkins University, Baltimore, MD, United States of America.
    Tseng SH; Department of Pathology, Johns Hopkins University, Baltimore, MD, United States of America.
    Das S; Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.
    Velasquez FC; Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.
    Karanam B; Department of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, Alabama, United States of America.
    Poddatoori D; Up Therapeutics LLC, Frederick, MD, United States of America.
    Patnam R; Prochem Organics, IDA Pashamylaram, Isnapur, Medak, Telangana, India.
    Rudek MA; Department of Oncology, Johns Hopkins University, Baltimore, MD, United States of America.; Department of Medicine, Johns Hopkins University, Baltimore, MD, United States of America.
    Chang YN; Up Therapeutics LLC, Frederick, MD, United States of America.
    Roden RBS; Department of Oncology, Johns Hopkins University, Baltimore, MD, United States of America.; Department of Pathology, Johns Hopkins University, Baltimore, MD, United States of America.
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    Źródło:
    PloS one [PLoS One] 2023 Jun 14; Vol. 18 (6), pp. e0285221. Date of Electronic Publication: 2023 Jun 14 (Print Publication: 2023).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Multiple Myeloma*
    Ovarian Neoplasms*
    Humans ; Male ; Female ; Animals ; Mice ; Cisplatin ; Proteasome Endopeptidase Complex ; Bortezomib/pharmacology ; Intracellular Signaling Peptides and Proteins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Enhanced T-Cell Priming and Improved Anti-Tumor Immunity through Lymphatic Delivery of Checkpoint Blockade Immunotherapy.
    Autorzy:
    Mantilla-Rojas C; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, USA.
    Velasquez FC; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, USA.
    Morton JE; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, USA.
    Clemente LC; Department of Translational Molecular Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
    Parra ER; Department of Translational Molecular Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
    Torres-Cabala C; Departments of Pathology and Dermatology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
    Sevick-Muraca EM; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, USA.
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    Źródło:
    Cancers [Cancers (Basel)] 2022 Apr 04; Vol. 14 (7). Date of Electronic Publication: 2022 Apr 04.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Role of miR-181c in Diet-induced obesity through regulation of lipid synthesis in liver.
    Autorzy:
    Akiyoshi K; Department of Anesthesiology and Critical Care Medicine, Baltimore, MD, United States of America.
    Boersma GJ; Department of Psychiatry & Behavioral Sciences, Baltimore, MD, United States of America.
    Johnson MD; Department of Psychiatry & Behavioral Sciences, Baltimore, MD, United States of America.
    Velasquez FC; Department of Anesthesiology and Critical Care Medicine, Baltimore, MD, United States of America.
    Dunkerly-Eyring B; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, United States of America.
    O'Brien S; Department of Psychiatry & Behavioral Sciences, Baltimore, MD, United States of America.
    Yamaguchi A; Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
    Steenbergen C; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, United States of America.
    Tamashiro KLK; Department of Psychiatry & Behavioral Sciences, Baltimore, MD, United States of America.
    Das S; Department of Anesthesiology and Critical Care Medicine, Baltimore, MD, United States of America.; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, United States of America.
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    Źródło:
    PloS one [PLoS One] 2021 Dec 08; Vol. 16 (12), pp. e0256973. Date of Electronic Publication: 2021 Dec 08 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Lipogenesis*/drug effects
    Lipogenesis*/genetics
    Obesity*/chemically induced
    Obesity*/genetics
    Obesity*/metabolism
    Triglycerides*/biosynthesis
    Triglycerides*/genetics
    Diet, High-Fat/*adverse effects
    Hepatocytes/*metabolism
    Liver/*metabolism
    MicroRNAs/*metabolism
    Animals ; Male ; Mice ; Mice, Knockout ; MicroRNAs/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Assessing lymphatic route of CSF outflow and peripheral lymphatic contractile activity during head-down tilt using near-infrared fluorescence imaging.
    Autorzy:
    Rasmussen JC; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center at Houston, Houston, TX, USA.
    Kwon S; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center at Houston, Houston, TX, USA.
    Pinal A; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center at Houston, Houston, TX, USA.
    Bareis A; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center at Houston, Houston, TX, USA.
    Velasquez FC; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center at Houston, Houston, TX, USA.
    Janssen CF; Center for Laboratory Animal Medicine and Care, The University of Texas Health Science Center at Houston, Houston, TX, USA.
    Morrow JR; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center at Houston, Houston, TX, USA.
    Fife CE; Department of Geriatrics, Baylor College of Medicine, Houston, TX, USA.; The Wound Care Clinic, CHI St. Luke's Health, The Woodlands Hospital, The Woodlands, TX, USA.
    Karni RJ; Department of Otorhinolaryngology, The University of Texas Health Science Center at Houston, Houston, TX, USA.
    Sevick-Muraca EM; Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center at Houston, Houston, TX, USA.
    Pokaż więcej
    Źródło:
    Physiological reports [Physiol Rep] 2020 Feb; Vol. 8 (4), pp. e14375.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Head-Down Tilt*
    Cerebrospinal Fluid/*physiology
    Lymphatic Vessels/*physiology
    Adult ; Aged ; Animals ; Female ; Gravitation ; Humans ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/physiology ; Lymphatic Vessels/diagnostic imaging ; Male ; Middle Aged ; Muscle Contraction ; Swine
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-4 z 4

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