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Wyszukujesz frazę ""Vinca Alkaloids"" wg kryterium: Temat


Tytuł :
Effect of lubiprostone on vinca alkaloid-induced constipation in patients with hematological malignancies: a propensity score-matched analysis.
Autorzy :
Kawada K; Department of Pharmacy, Kochi Medical Hospital School, 185-1 Kohasu, Oko town, Nankoku City, Kochi, Japan. .; Department of Biomedical Science, Kochi Medical Graduate School, 185-1 Kohasu, Oko town, Nankoku, Kochi, Japan. .
Ohta T; Department of Neurosurgery, Kochi Health Sciences Center, Ike 2125-1,, Kochi City, Kochi, Japan.
Fukuda H; Department of Neurosurgery, Kochi Medical Hospital School, 185-1 Kohasu, Oko town, Nankoku City, Kochi, Japan.
Hayashi T; Department of Pharmaceutical and Health Care Management, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, Japan.
Tanaka K; Pharmaceutical Department, Kochi Health Sciences Center, Ike 2125-1,, Kochi City, Kochi, Japan.
Imai T; Department of Hematology, Kochi Health Sciences Center, Ike 2125-1,, Kochi City, Kochi, Japan.
Morita Y; Department of Pharmacy, Kochi Medical Hospital School, 185-1 Kohasu, Oko town, Nankoku City, Kochi, Japan.
Miyamura M; Department of Pharmacy, Kochi Medical Hospital School, 185-1 Kohasu, Oko town, Nankoku City, Kochi, Japan.; Department of Biomedical Science, Kochi Medical Graduate School, 185-1 Kohasu, Oko town, Nankoku, Kochi, Japan.
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Źródło :
Annals of hematology [Ann Hematol] 2020 Oct; Vol. 99 (10), pp. 2429-2436. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*adverse effects
Chloride Channel Agonists/*therapeutic use
Constipation/*drug therapy
Hematologic Neoplasms/*drug therapy
Lubiprostone/*therapeutic use
Lymphoma/*drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Vinca Alkaloids/*adverse effects
Aged ; Aged, 80 and over ; Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Constipation/chemically induced ; Cyclophosphamide/administration & dosage ; Doxorubicin/administration & dosage ; Drug Evaluation ; Drug Therapy, Combination ; Famotidine/therapeutic use ; Female ; Humans ; Laxatives/pharmacology ; Laxatives/therapeutic use ; Magnesium Oxide/therapeutic use ; Male ; Middle Aged ; Narcotics/adverse effects ; Prednisone/administration & dosage ; Propensity Score ; Proton Pump Inhibitors/therapeutic use ; Retrospective Studies ; Risk Factors ; Sennosides/therapeutic use ; Vinca Alkaloids/administration & dosage ; Vincristine/administration & dosage
SCR Protocol :
CHOP protocol
Czasopismo naukowe
Tytuł :
Optimized preparation of vinpocetine micelles and in vivo evaluation of its pharmacokinetics in rats.
Autorzy :
Zhou J; The Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, China.
Zhang W; The Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, China.
Pang J; The Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, China.
Wang X; The Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, China.
Zheng Z; The Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, China.
Li Y; The Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, China.
Yang F; The Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Department of Pharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems, Guangdong Pharmaceutical University, Guangzhou, China.
Yang W; The Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, China.
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Źródło :
Pharmaceutical development and technology [Pharm Dev Technol] 2020 Apr; Vol. 25 (4), pp. 464-471. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Journal Article
MeSH Terms :
Delayed-Action Preparations/*chemistry
Neuroprotective Agents/*administration & dosage
Polyesters/*chemistry
Polyethylene Glycols/*chemistry
Vasodilator Agents/*administration & dosage
Vinca Alkaloids/*administration & dosage
Animals ; Drug Liberation ; Male ; Micelles ; Neuroprotective Agents/pharmacokinetics ; Rats ; Rats, Sprague-Dawley ; Vasodilator Agents/pharmacokinetics ; Vinca Alkaloids/pharmacokinetics
Czasopismo naukowe
Tytuł :
Vinpocetine Suppresses Streptococcus pneumoniae -Induced Inflammation via Inhibition of ERK1 by CYLD.
Autorzy :
Komatsu K; Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Nam DH; Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Lee JY; Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.; College of Pharmacy, Chung-Ang University, Dongjak-gu, Seoul 06974, South Korea; and.
Yoneda G; Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Yan C; Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642.
Li JD; Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303; .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Feb 15; Vol. 204 (4), pp. 933-942. Date of Electronic Publication: 2020 Jan 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Deubiquitinating Enzyme CYLD/*metabolism
Otitis Media/*drug therapy
Pneumococcal Infections/*drug therapy
Vinca Alkaloids/*pharmacology
Animals ; Cell Line ; Deubiquitinating Enzyme CYLD/genetics ; Disease Models, Animal ; Ear, Middle/cytology ; Ear, Middle/drug effects ; Ear, Middle/immunology ; Epithelial Cells ; Gene Knockdown Techniques ; Humans ; MAP Kinase Signaling System/drug effects ; MAP Kinase Signaling System/immunology ; Mice ; Mice, Knockout ; Mitogen-Activated Protein Kinase 3/metabolism ; Otitis Media/immunology ; Otitis Media/microbiology ; Pneumococcal Infections/immunology ; Pneumococcal Infections/microbiology ; RNA, Small Interfering/metabolism ; Streptococcus pneumoniae/immunology ; Streptococcus pneumoniae/isolation & purification ; Up-Regulation/drug effects ; Vinca Alkaloids/therapeutic use
Czasopismo naukowe
Tytuł :
Personalized medicine: Vinpocetine to reverse effects of GABRB3 mutation.
Autorzy :
Billakota S; NYU Langone Comprehensive Epilepsy Center, New York University Langone School of Medicine, New York, New York.
Andresen JM; Pairnomix, Plymouth, Minnesota.
Gay BC; Pairnomix, Plymouth, Minnesota.
Stewart GR; Pairnomix, Plymouth, Minnesota.
Fedorov NB; Charles River Discovery, Cleveland, Ohio.
Gerlach AC; Icagen, Durham, North Carolina.
Devinsky O; NYU Langone Comprehensive Epilepsy Center, Department of Neurology, Neurosurgery, and Psychiatry, New York University Langone School of Medicine, New York, New York.; Saint Barnabas Institute of Neurology and Neurosurgery, Livingston, New Jersey.
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Źródło :
Epilepsia [Epilepsia] 2019 Dec; Vol. 60 (12), pp. 2459-2465. Date of Electronic Publication: 2019 Nov 22.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Lennox Gastaut Syndrome/*drug therapy
Lennox Gastaut Syndrome/*genetics
Mutation/*genetics
Precision Medicine/*methods
Receptors, GABA-A/*genetics
Vinca Alkaloids/*therapeutic use
Adult ; Dose-Response Relationship, Drug ; Electroencephalography/drug effects ; Electroencephalography/methods ; Female ; HEK293 Cells ; Humans ; Lennox Gastaut Syndrome/diagnosis ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Vinca Alkaloids/pharmacology ; gamma-Aminobutyric Acid/pharmacology
Czasopismo naukowe
Tytuł :
Synthesis and biological evaluation of [ F]fluorovinpocetine, a potential PET radioligand for TSPO imaging.
Autorzy :
Nag S; Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden. Electronic address: .
Krasikova R; Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden; N.P. Bechtereva Institute of Human Brain Russian Academy of Sciences, St.-Petersburg, Russia.
Airaksinen AJ; Department of Chemistry - Radiochemistry, University of Helsinki, Finland.
Arakawa R; Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden.
Petukhovd M; Petersburg Nuclear Physics Institute named after B.P. Konstantinov, NRC 'Kurchatov Institute', Gatchina, Russia; Peter the Great St.-Petersburg Polytechnic University, St.-Petersburg, Russia.
Gulyas B; Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Aug 15; Vol. 29 (16), pp. 2270-2274. Date of Electronic Publication: 2019 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Positron-Emission Tomography*
Radiopharmaceuticals/*chemistry
Receptors, GABA/*analysis
Vinca Alkaloids/*chemistry
Animals ; Dose-Response Relationship, Drug ; Fluorine Radioisotopes ; Ligands ; Macaca fascicularis ; Models, Molecular ; Molecular Structure ; Radiopharmaceuticals/chemical synthesis ; Radiopharmaceuticals/pharmacokinetics ; Structure-Activity Relationship ; Tissue Distribution ; Vinca Alkaloids/chemical synthesis ; Vinca Alkaloids/pharmacokinetics
Czasopismo naukowe
Tytuł :
Superiority of TPGS-loaded micelles in the brain delivery of vinpocetine via administration of thermosensitive intranasal gel.
Autorzy :
Ahmed TA; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo 11651, Egypt.
El-Say KM; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo 11651, Egypt.
Ahmed OA; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Aljaeid BM; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2019 Jul 23; Vol. 14, pp. 5555-5567. Date of Electronic Publication: 2019 Jul 23 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Micelles*
Temperature*
Gels/*administration & dosage
Vinca Alkaloids/*administration & dosage
Vitamin E/*chemistry
Administration, Intranasal ; Animals ; Biological Availability ; Brain/metabolism ; Cattle ; Drug Carriers/chemistry ; Drug Delivery Systems/methods ; Lipids/chemistry ; Male ; Nanoparticles/chemistry ; Nanoparticles/ultrastructure ; Particle Size ; Rats, Sprague-Dawley ; Solubility ; Tissue Distribution ; Vinca Alkaloids/blood ; Vinca Alkaloids/pharmacokinetics
Czasopismo naukowe
Tytuł :
Chemotherapy-Induced First Bite Syndrome: A Case Report in a Patient With Hodgkin Lymphoma.
Autorzy :
Valenzuela CV; 1 Department of Otolaryngology-Head & Neck Surgery, Washington University School of Medicine in St Louis, St Louis, MO, USA.
Bartlett NL; 2 Division of Oncology, Department of Internal Medicine, Washington University School of Medicine in St Louis, St Louis, MO, USA.
Bradley JP; 1 Department of Otolaryngology-Head & Neck Surgery, Washington University School of Medicine in St Louis, St Louis, MO, USA.
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Źródło :
Ear, nose, & throat journal [Ear Nose Throat J] 2019 Jun; Vol. 98 (5), pp. E30-E31. Date of Electronic Publication: 2019 Apr 08.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Facial Pain*/chemically induced
Facial Pain*/diagnosis
Facial Pain*/physiopathology
Facial Pain*/therapy
Hodgkin Disease*/drug therapy
Hodgkin Disease*/pathology
Vinca Alkaloids*/administration & dosage
Vinca Alkaloids*/adverse effects
Botulinum Toxins, Type A/*administration & dosage
Aged, 80 and over ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Humans ; Male ; Neoplasm Staging ; Neuromuscular Agents/administration & dosage ; Positron Emission Tomography Computed Tomography/methods ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Neuroprotective effects of novel nanosystems simultaneously loaded with vinpocetine and piracetam after intranasal administration.
Autorzy :
Nasr M; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt. Electronic address: .
Wahdan SA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
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Źródło :
Life sciences [Life Sci] 2019 Jun 01; Vol. 226, pp. 117-129. Date of Electronic Publication: 2019 Apr 11.
Typ publikacji :
Journal Article
MeSH Terms :
Memory/*drug effects
Piracetam/*pharmacology
Vinca Alkaloids/*pharmacology
Administration, Intranasal ; Animals ; Brain/drug effects ; Drug Compounding/methods ; Drug Delivery Systems/methods ; Male ; Maze Learning/drug effects ; Memory/physiology ; Memory Disorders/drug therapy ; Nanoparticles/therapeutic use ; Nasal Mucosa/drug effects ; Neuroprotective Agents ; Piracetam/administration & dosage ; Rats ; Rats, Wistar ; Scopolamine/pharmacology ; Sheep ; Vinca Alkaloids/administration & dosage
Czasopismo naukowe
Tytuł :
Synthesis and characterization of amphiphilic star-shaped copolymers based on β-cyclodextrin for micelles drug delivery.
Autorzy :
Lv J; a Guangdong Provincial Engineering & Technology Research Center for Topical Precise Drug Delivery System, School of Pharmacy , Guangdong Pharmaceutical University , Guangzhou , China.
Liang R; a Guangdong Provincial Engineering & Technology Research Center for Topical Precise Drug Delivery System, School of Pharmacy , Guangdong Pharmaceutical University , Guangzhou , China.
Xia Z; a Guangdong Provincial Engineering & Technology Research Center for Topical Precise Drug Delivery System, School of Pharmacy , Guangdong Pharmaceutical University , Guangzhou , China.
Li Y; b Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems , Guangdong Pharmaceutical University , Guangzhou , China.; c Guangdong Provincial Engineering Center for Modified-released Pharmaceutical Products , Guangdong Pharmaceutical University , Guangzhou , China.
Lv Z; b Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems , Guangdong Pharmaceutical University , Guangzhou , China.; c Guangdong Provincial Engineering Center for Modified-released Pharmaceutical Products , Guangdong Pharmaceutical University , Guangzhou , China.
Hou D; a Guangdong Provincial Engineering & Technology Research Center for Topical Precise Drug Delivery System, School of Pharmacy , Guangdong Pharmaceutical University , Guangzhou , China.
Yu L; a Guangdong Provincial Engineering & Technology Research Center for Topical Precise Drug Delivery System, School of Pharmacy , Guangdong Pharmaceutical University , Guangzhou , China.
Chen G; a Guangdong Provincial Engineering & Technology Research Center for Topical Precise Drug Delivery System, School of Pharmacy , Guangdong Pharmaceutical University , Guangzhou , China.
Liu Y; d School of Chemistry and Chemical Engineering , Guangdong Pharmaceutical University , Zhongshan , China.
Yang F; a Guangdong Provincial Engineering & Technology Research Center for Topical Precise Drug Delivery System, School of Pharmacy , Guangdong Pharmaceutical University , Guangzhou , China.
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Źródło :
Drug development and industrial pharmacy [Drug Dev Ind Pharm] 2019 Jun; Vol. 45 (6), pp. 1017-1028. Date of Electronic Publication: 2019 Mar 28.
Typ publikacji :
Journal Article
MeSH Terms :
Delayed-Action Preparations/*pharmacokinetics
Drug Carriers/*chemistry
Polymers/*chemistry
Vinca Alkaloids/*pharmacokinetics
beta-Cyclodextrins/*chemistry
Animals ; Biological Availability ; Delayed-Action Preparations/administration & dosage ; Drug Compounding/methods ; Drug Evaluation, Preclinical ; Drug Liberation ; Drug Stability ; Hydrogen-Ion Concentration ; Hydrophobic and Hydrophilic Interactions ; Injections, Intravenous ; Micelles ; Rats ; Rats, Sprague-Dawley ; Surface-Active Agents/chemistry ; Tissue Distribution ; Vinca Alkaloids/administration & dosage
Czasopismo naukowe
Tytuł :
Vinpocetine in the treatment of poststroke cognitive dysfunction: A protocol for systematic review and meta-analysis.
Autorzy :
Liu Y; Department of Neurology, Fifth Central Hospital of Tianjin, Binhai Hospital of Peking University, Tianjin, 300450.
Yin Y; Department of Neurology, Fifth Central Hospital of Tianjin, Binhai Hospital of Peking University, Tianjin, 300450.
Lu QL; Department of Neurology, Fifth Central Hospital of Tianjin, Binhai Hospital of Peking University, Tianjin, 300450.
Dan Y; Department of Neurology, Fifth Central Hospital of Tianjin, Binhai Hospital of Peking University, Tianjin, 300450.
Xu MS; Department of Neurology, Fifth Central Hospital of Tianjin, Binhai Hospital of Peking University, Tianjin, 300450.
Song G; Department of Clinical Medicine, Xinxiang Medical University, Henan, 453003, China.
Li C; Department of Neurology, Fifth Central Hospital of Tianjin, Binhai Hospital of Peking University, Tianjin, 300450.
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Źródło :
Medicine [Medicine (Baltimore)] 2019 Feb; Vol. 98 (6), pp. e13685.
Typ publikacji :
Journal Article; Meta-Analysis; Review
MeSH Terms :
Cognitive Dysfunction/*drug therapy
Cognitive Dysfunction/*etiology
Nootropic Agents/*therapeutic use
Stroke/*complications
Vinca Alkaloids/*therapeutic use
Humans ; Nootropic Agents/administration & dosage ; Nootropic Agents/adverse effects ; Quality of Life ; Randomized Controlled Trials as Topic ; Research Design ; Vinca Alkaloids/administration & dosage ; Vinca Alkaloids/adverse effects
Czasopismo naukowe
Tytuł :
Pharmacokinetics, Tissue Distribution, Plasma Protein Binding Studies of 10-Dehydroxyl-12-Demethoxy-Conophylline, a Novel Anti-Tumor Candidate, in Rats.
Autorzy :
Jiang C; School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China. .
Li J; School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China. .; School of Environmental and Chemical Engineering, Zhaoqing University, Zhaoqing 526061, China. .
Cai X; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. .
Li N; School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China. .
Guo Y; School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China. .
Wang D; School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China. .
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2019 Jan 14; Vol. 24 (2). Date of Electronic Publication: 2019 Jan 14.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacokinetics
Blood Proteins/*metabolism
Vinca Alkaloids/*pharmacokinetics
Animals ; Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Agents, Phytogenic/chemistry ; Female ; Male ; Molecular Structure ; Protein Binding ; Rats ; Tissue Distribution ; Vinca Alkaloids/administration & dosage ; Vinca Alkaloids/chemistry
Czasopismo naukowe
Tytuł :
Vinpocetine regulates levels of circulating TLRs in Parkinson's disease patients.
Autorzy :
Ping Z; Department of Neurology, Jiangxi Provincial People's Hospital, No, 92 Aiguo Road, Donghu District, Nanchang, 330006, Jiangxi, China. .
Xiaomu W; Department of Neurology, Jiangxi Provincial People's Hospital, No, 92 Aiguo Road, Donghu District, Nanchang, 330006, Jiangxi, China.
Xufang X; Department of Neurology, Jiangxi Provincial People's Hospital, No, 92 Aiguo Road, Donghu District, Nanchang, 330006, Jiangxi, China.
Liang S; Department of Cardiology, Jiangxi Provincial People's Hospital, No, 92 Aiguo Road, Donghu District, Nanchang, 330006, Jiangxi, China. .
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Źródło :
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2019 Jan; Vol. 40 (1), pp. 113-120. Date of Electronic Publication: 2018 Oct 12.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroprotective Agents/*therapeutic use
Parkinson Disease/*blood
Parkinson Disease/*drug therapy
Toll-Like Receptors/*blood
Vinca Alkaloids/*therapeutic use
Aged ; Biomarkers/blood ; Case-Control Studies ; Cohort Studies ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Neuroprotective Agents/pharmacology ; Random Allocation ; Toll-Like Receptors/antagonists & inhibitors ; Vinca Alkaloids/pharmacology
Czasopismo naukowe
Tytuł :
Extended-release vinpocetine: a possible adjuvant treatment for focal onset epileptic seizures.
Autorzy :
Garza-Morales S; Hospital Infantil de México Federico Gómez, Ciudad de México.
Briceño-González E; Instituto Nacional de Neurología y Neurocirugía, Ciudad de México.
Ceja-Moreno H; Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jal.
Ruiz-Sandoval JL; Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jal.
Góngora-Rivera F; Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, N.L.
Rodríguez-Leyva I; Hospital Ángeles, San Luis Potosí, S.L.P. México.
Alonso-Rivera CG; Hospital Ángeles, San Luis Potosí, S.L.P. México.
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Transliterated Title :
Vinpocetina de liberación prolongada: un posible tratamiento adyuvante en crisis epiléptica de inicio focal.
Źródło :
Boletin medico del Hospital Infantil de Mexico [Bol Med Hosp Infant Mex] 2019; Vol. 76 (5), pp. 215-224.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticonvulsants/*administration & dosage
Epilepsies, Partial/*drug therapy
Vinca Alkaloids/*administration & dosage
Adolescent ; Adult ; Anticonvulsants/adverse effects ; Child ; Delayed-Action Preparations ; Double-Blind Method ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Treatment Outcome ; Vinca Alkaloids/adverse effects ; Young Adult
Czasopismo naukowe
Tytuł :
Formulation and clinical investigation of optimized vinpocetine lyoplant-tabs: new strategy in development of buccal solid dosage form.
Autorzy :
Ahmed TA; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, .; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt, .
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Źródło :
Drug design, development and therapy [Drug Des Devel Ther] 2018 Dec 28; Vol. 13, pp. 205-220. Date of Electronic Publication: 2018 Dec 28 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Vinca Alkaloids/*pharmacokinetics
Drug Compounding ; Freeze Drying ; Healthy Volunteers ; Humans ; Povidone/chemistry ; Solubility ; Tablets/chemistry ; Tablets/pharmacokinetics ; Thermodynamics ; Vinca Alkaloids/chemistry ; Vinyl Compounds/chemistry
Czasopismo naukowe
Tytuł :
Vinpocetine halts ketamine-induced schizophrenia-like deficits in rats: impact on BDNF and GSK-3β/β-catenin pathway.
Autorzy :
Ahmed HI; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, 11754, Egypt. .
Abdel-Sattar SA; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, 11754, Egypt.
Zaky HS; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, 11754, Egypt.
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Źródło :
Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2018 Dec; Vol. 391 (12), pp. 1327-1338. Date of Electronic Publication: 2018 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Antipsychotic Agents/*therapeutic use
Schizophrenia/*drug therapy
Vinca Alkaloids/*therapeutic use
Animals ; Antipsychotic Agents/pharmacology ; Behavior, Animal/drug effects ; Brain-Derived Neurotrophic Factor/metabolism ; Glycogen Synthase Kinase 3 beta/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Ketamine ; Male ; Malondialdehyde/metabolism ; Oxidative Stress/drug effects ; Rats, Sprague-Dawley ; Schizophrenia/chemically induced ; Schizophrenia/metabolism ; Signal Transduction/drug effects ; Vinca Alkaloids/pharmacology ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Antibiotics potentiating potential of catharanthine against superbug Pseudomonas aeruginosa.
Autorzy :
Dwivedi GR; a Microbiology Department , ICMR-Regional Medical Research Centre Bhubaneswar , Bhubaneswar 751023 , Odisha , India.
Tyagi R; b Medicinal Chemistry Department , Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) , P.O.- CIMAP, Lucknow 226015 , India.
Sanchita; c Biotechnology Division , Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) , P.O.- CIMAP, Lucknow 226015 , India.
Tripathi S; c Biotechnology Division , Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) , P.O.- CIMAP, Lucknow 226015 , India.
Pati S; a Microbiology Department , ICMR-Regional Medical Research Centre Bhubaneswar , Bhubaneswar 751023 , Odisha , India.
Srivastava SK; b Medicinal Chemistry Department , Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) , P.O.- CIMAP, Lucknow 226015 , India.
Darokar MP; c Biotechnology Division , Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) , P.O.- CIMAP, Lucknow 226015 , India.
Sharma A; c Biotechnology Division , Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) , P.O.- CIMAP, Lucknow 226015 , India.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2018 Dec; Vol. 36 (16), pp. 4270-4284. Date of Electronic Publication: 2018 Jan 02.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Bacterial Proteins/*antagonists & inhibitors
Drug Resistance, Multiple, Bacterial/*drug effects
Pseudomonas aeruginosa/*drug effects
Vinca Alkaloids/*pharmacology
Anti-Bacterial Agents/chemistry ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Catharanthus/chemistry ; Drug Resistance, Multiple, Bacterial/genetics ; Drug Synergism ; Humans ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Molecular Structure ; Plant Leaves/chemistry ; Protein Binding ; Protein Domains ; Pseudomonas aeruginosa/metabolism ; Vinca Alkaloids/chemistry
Czasopismo naukowe
Tytuł :
Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead.
Autorzy :
Martino E; Department of Earth and Environmental Sciences, University of Pavia, Via S. Epifanio 14, 27100 Pavia, Italy.
Casamassima G; Department of Drug Sciences, Medicinal Chemistry Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Castiglione S; Department of Drug Sciences, Medicinal Chemistry Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Cellupica E; Department of Drug Sciences, Medicinal Chemistry Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Pantalone S; Department of Drug Sciences, Medicinal Chemistry Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Papagni F; Department of Drug Sciences, Medicinal Chemistry Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Rui M; Department of Drug Sciences, Medicinal Chemistry Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Siciliano AM; Department of Drug Sciences, Medicinal Chemistry Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Collina S; Department of Drug Sciences, Medicinal Chemistry Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2018 Sep 15; Vol. 28 (17), pp. 2816-2826. Date of Electronic Publication: 2018 Jun 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Neoplasms/*drug therapy
Vinca Alkaloids/*therapeutic use
Animals ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Humans ; Neoplasms/pathology ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/pathology ; Vinca Alkaloids/chemistry
Czasopismo naukowe
Tytuł :
Alkaloid and iridoid glucosides from Palicourea luxurians (Rubiaceae: Palicoureeae) indicate tryptamine- and tryptophan-iridoid alkaloid formation apart the strictosidine pathway.
Autorzy :
Kornpointner C; Department of Organic Chemistry, University of Vienna, Währinger Strasse 38, A-1090, Vienna, Austria.
Berger A; Department of Botany and Biodiversity Research, University of Vienna, Rennweg 14, A-1030, Vienna, Austria.
Traxler F; Department of Organic Chemistry, University of Vienna, Währinger Strasse 38, A-1090, Vienna, Austria.
Hadžiabdić A; Department of Organic Chemistry, University of Vienna, Währinger Strasse 38, A-1090, Vienna, Austria.
Massar M; Department of Organic Chemistry, University of Vienna, Währinger Strasse 38, A-1090, Vienna, Austria.
Matek J; Department of Organic Chemistry, University of Vienna, Währinger Strasse 38, A-1090, Vienna, Austria.
Brecker L; Department of Organic Chemistry, University of Vienna, Währinger Strasse 38, A-1090, Vienna, Austria. Electronic address: .
Schinnerl J; Department of Botany and Biodiversity Research, University of Vienna, Rennweg 14, A-1030, Vienna, Austria. Electronic address: .
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Źródło :
Phytochemistry [Phytochemistry] 2020 May; Vol. 173, pp. 112296. Date of Electronic Publication: 2020 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids*
Rubiaceae*
Secologanin Tryptamine Alkaloids*
Iridoid Glucosides ; Iridoids ; Tryptamines ; Tryptophan ; Vinca Alkaloids
Czasopismo naukowe
Tytuł :
Effect of different doses of borneol on the pharmacokinetics of vinpocetine in rat plasma and brain after intraocular administration.
Autorzy :
Ma Q; Department of Pharmaceutics, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China.
Dai M; Department of Pharmaceutics, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China.
Zhang H; Department of Pharmaceutics, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China.
Bai L; Department of Pharmaceutics, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China.
He N; Department of Pharmaceutics, College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China.; Institute of Pharmaceutics, Anhui Academy of Chinese Medical Sciences, Hefei, China.; Education Office of Anhui Province, Engineering Technology Research Center of Modernized Pharmaceutics, Hefei, China.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2020 May; Vol. 50 (5), pp. 580-587. Date of Electronic Publication: 2019 Aug 28.
Typ publikacji :
Journal Article
MeSH Terms :
Camphanes/*metabolism
Vinca Alkaloids/*pharmacokinetics
Animals ; Brain/metabolism ; Dose-Response Relationship, Drug ; Injections, Intraocular ; Plasma/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Autorzy :
Zhu M; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Liu H; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Sun K; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Liu J; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Mou Y; Institute of Neural Regeneration and Repair and Department of Neurology, The First Hospital of Yichang, Three Gorges University College of Medicine, Yichang, Hubei, 443000, China.
Qi D; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Zhou C; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Abudunaibi M; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Tasiken B; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Li J; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.
Cheng H; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China. Electronic address: .
Huang H; Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Mar; Vol. 123, pp. 109769. Date of Electronic Publication: 2019 Dec 15.
Typ publikacji :
Journal Article
MeSH Terms :
Ovariectomy*
Bone Resorption/*etiology
Osteogenesis/*drug effects
RANK Ligand/*pharmacology
Vinca Alkaloids/*pharmacology
Actins/metabolism ; Animals ; Bone Resorption/genetics ; Cytoprotection/drug effects ; Female ; Gene Expression Regulation/drug effects ; Male ; Mice, Inbred C57BL ; Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Osteoclasts/drug effects ; Osteoclasts/pathology ; Osteogenesis/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe

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