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Tytuł :
Nanodissection of Selected Viral Particles by Scanning Transmission Electron Microscopy/Focused Ion Beam for Genetic Identification.
Autorzy :
Horvitz D; Electron Microscopy, Thermo Fisher Israel Ltd., HaYarden 1 street, Airport City 7019900, Israel.
Milrot E; Department of Infectious Diseases, Israel Institute for Biological Research, P.O.B 19, Ness Ziona 74100, Israel.
Luria N; Department of Plant Pathology, ARO, The Volcani Center, Rishon Lezion 50250, Israel.
Makdasi E; Department of Infectious Diseases, Israel Institute for Biological Research, P.O.B 19, Ness Ziona 74100, Israel.
Beth-Din A; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, P.O.B 19, Ness Ziona 74100, Israel.
Glinert I; Department of Infectious Diseases, Israel Institute for Biological Research, P.O.B 19, Ness Ziona 74100, Israel.
Dombrovsky A; Department of Plant Pathology, ARO, The Volcani Center, Rishon Lezion 50250, Israel.
Laskar O; Department of Infectious Diseases, Israel Institute for Biological Research, P.O.B 19, Ness Ziona 74100, Israel.
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Źródło :
Analytical chemistry [Anal Chem] 2021 Oct 05; Vol. 93 (39), pp. 13126-13133. Date of Electronic Publication: 2021 Sep 22.
Typ publikacji :
Journal Article
MeSH Terms :
Virion*/genetics
Humans ; Microscopy, Electron, Scanning Transmission
Czasopismo naukowe
Tytuł :
Just Seeing Is Not Enough for Believing: Immunolabelling as Indisputable Proof of SARS-CoV-2 Virions in Infected Tissue.
Autorzy :
Erman A; Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Wechtersbach K; Institute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Velkavrh D; Institute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Pleško J; Institute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Frelih M; Institute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Kojc N; Institute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
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Źródło :
Viruses [Viruses] 2021 Sep 13; Vol. 13 (9). Date of Electronic Publication: 2021 Sep 13.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*virology
SARS-CoV-2/*isolation & purification
Virion/*isolation & purification
Coronavirus Nucleocapsid Proteins/analysis ; Humans ; Immunohistochemistry ; Microscopy, Immunoelectron ; Nasopharynx/virology ; Phosphoproteins/analysis ; SARS-CoV-2/ultrastructure ; Virion/ultrastructure
Czasopismo naukowe
Tytuł :
Presumed SARS-CoV-2 Viral Particles in the Human Retina of Patients With COVID-19.
Autorzy :
Araujo-Silva CA; Instituto Nacional de Ciência e Tecnologia em Biologia Estrutural e Bioimagens-INBEB, Rio de Janeiro, Brazil.; Laboratório de Ultraestrutura Celular Hertha Meyer, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Centro Nacional de Biologia Estrutural e Bioimagens-CENABIO, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Marcos AAA; São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; Instituto da Visão-IPEPO, São Paulo, Brazil.
Marinho PM; São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; Instituto da Visão-IPEPO, São Paulo, Brazil.; Hospital Municipal de Barueri Dr. Francisco Moran, Barueri, Brazil.
Branco AMC; São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.
Roque A; Hospital Municipal de Barueri Dr. Francisco Moran, Barueri, Brazil.
Romano AC; São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; Instituto da Visão-IPEPO, São Paulo, Brazil.
Matuoka ML; Hospital Municipal de Barueri Dr. Francisco Moran, Barueri, Brazil.
Farah M; São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; Instituto da Visão-IPEPO, São Paulo, Brazil.
Burnier M; Mc Gill University, Montreal, Quebec, Canada.
Moraes NF; Hospital Municipal de Barueri Dr. Francisco Moran, Barueri, Brazil.
Tierno PFGMM; Hospital Municipal de Barueri Dr. Francisco Moran, Barueri, Brazil.
Schor P; São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; Instituto da Visão-IPEPO, São Paulo, Brazil.
Sakamoto V; São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.
Nascimento H; São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; Instituto da Visão-IPEPO, São Paulo, Brazil.; Hospital Municipal de Barueri Dr. Francisco Moran, Barueri, Brazil.
de Sousa W; Instituto Nacional de Ciência e Tecnologia em Biologia Estrutural e Bioimagens-INBEB, Rio de Janeiro, Brazil.; Laboratório de Ultraestrutura Celular Hertha Meyer, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Centro Nacional de Biologia Estrutural e Bioimagens-CENABIO, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Belfort R Jr; São Paulo Hospital, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; Instituto da Visão-IPEPO, São Paulo, Brazil.
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Źródło :
JAMA ophthalmology [JAMA Ophthalmol] 2021 Sep 01; Vol. 139 (9), pp. 1015-1021.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*virology
Retina/*virology
SARS-CoV-2/*isolation & purification
Virion/*isolation & purification
Aged ; COVID-19/diagnosis ; COVID-19/mortality ; Female ; Fluorescent Antibody Technique ; Humans ; Male ; Microscopy, Electron, Transmission ; Retina/ultrastructure ; SARS-CoV-2/ultrastructure ; Virion/ultrastructure
Czasopismo naukowe
Tytuł :
Quantifying Viral Particle Aerosolization Risk During Tracheostomy Surgery and Tracheostomy Care.
Autorzy :
Berges AJ; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Lina IA; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Ospino R; Johns Hopkins University School of Medicine, Baltimore, Maryland.
Tsai HW; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Brenner MJ; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor.
Pandian V; Department of Nursing Faculty, and Outcomes After Critical Illness and Surgery (OACIS) Research Group, Johns Hopkins University, Baltimore, Maryland.
Rule AM; Department of Environmental Health and Engineering, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Hillel AT; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland.
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Źródło :
JAMA otolaryngology-- head & neck surgery [JAMA Otolaryngol Head Neck Surg] 2021 Sep 01; Vol. 147 (9), pp. 797-803.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Aerosols*
Medical Staff, Hospital*
Virion*
Infection Control/*methods
Infectious Disease Transmission, Patient-to-Professional/*prevention & control
Tracheostomy/*adverse effects
Animals ; COVID-19/prevention & control ; COVID-19/transmission ; Comparative Effectiveness Research ; Electrocoagulation/adverse effects ; Hot Temperature ; Humans ; Humidity ; Manikins ; Masks ; Risk Factors ; SARS-CoV-2 ; Swine ; Tracheostomy/instrumentation
Czasopismo naukowe
Tytuł :
Emerging roles of extracellular vesicles in COVID-19, a double-edged sword?
Autorzy :
Xia X; Center for Translational Neurodegeneration and Regenerative Therapy, Shanghai Tenth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.; Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.
Yuan P; Department of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Liu Y; Department of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Wang Y; Center for Translational Neurodegeneration and Regenerative Therapy, Shanghai Tenth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.; Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.
Cao W; Department of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Zheng JC; Center for Translational Neurodegeneration and Regenerative Therapy, Shanghai Tenth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.; Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.; Collaborative Innovation Center for Brain Science, Tongji University, Shanghai, China.
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Źródło :
Immunology [Immunology] 2021 Aug; Vol. 163 (4), pp. 416-430. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*virology
Extracellular Vesicles/*virology
Lung/*virology
Mesenchymal Stem Cells/*metabolism
SARS-CoV-2/*pathogenicity
Virion/*metabolism
Animals ; Antiviral Agents/administration & dosage ; COVID-19/drug therapy ; COVID-19/immunology ; COVID-19/metabolism ; COVID-19/therapy ; COVID-19 Vaccines/administration & dosage ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/metabolism ; Cytokine Release Syndrome/virology ; Cytokines/metabolism ; Drug Carriers ; Extracellular Vesicles/immunology ; Extracellular Vesicles/metabolism ; Extracellular Vesicles/transplantation ; Host-Pathogen Interactions ; Humans ; Inflammation Mediators/metabolism ; Lung/immunology ; Lung/metabolism ; Mesenchymal Stem Cells/immunology ; SARS-CoV-2/immunology ; Virion/immunology
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Characterization of HIV-1 virus-like particles and determination of Gag stoichiometry for different production platforms.
Autorzy :
Lavado-García J; Grup d'Enginyeria Cel·lular i Bioprocessos, Department of Chemical, Biological and Environmental Engineering, Escola d'Enginyeria, Universitat Autònoma de Barcelona, Campus de Bellaterra, Cerdanyola del Vallès, Barcelona, Spain.
Jorge I; Laboratory of Cardiovascular Proteomics, Vascular Physiopathology area, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, Madrid, Spain.; CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
Boix-Besora A; Grup d'Enginyeria Cel·lular i Bioprocessos, Department of Chemical, Biological and Environmental Engineering, Escola d'Enginyeria, Universitat Autònoma de Barcelona, Campus de Bellaterra, Cerdanyola del Vallès, Barcelona, Spain.
Vázquez J; Laboratory of Cardiovascular Proteomics, Vascular Physiopathology area, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, Madrid, Spain.; CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
Gòdia F; Grup d'Enginyeria Cel·lular i Bioprocessos, Department of Chemical, Biological and Environmental Engineering, Escola d'Enginyeria, Universitat Autònoma de Barcelona, Campus de Bellaterra, Cerdanyola del Vallès, Barcelona, Spain.
Cervera L; Grup d'Enginyeria Cel·lular i Bioprocessos, Department of Chemical, Biological and Environmental Engineering, Escola d'Enginyeria, Universitat Autònoma de Barcelona, Campus de Bellaterra, Cerdanyola del Vallès, Barcelona, Spain.
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2021 Jul; Vol. 118 (7), pp. 2660-2675. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Vaccines, Virus-Like Particle*
Virion*/chemistry
Virion*/genetics
gag Gene Products, Human Immunodeficiency Virus*/analysis
gag Gene Products, Human Immunodeficiency Virus*/chemistry
gag Gene Products, Human Immunodeficiency Virus*/genetics
COVID-19 Vaccines ; HEK293 Cells ; HIV-1/genetics ; Humans
Czasopismo naukowe
Tytuł :
Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity.
Autorzy :
Diehl WE; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.
Guney MH; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.
Vanzo T; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.
Kyawe PP; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.
White JM; Department of Cell Biology, University of Virginia, Charlottesville, VA 22908, USA.
Pizzato M; Department of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.
Luban J; Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
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Źródło :
Viruses [Viruses] 2021 Jun 30; Vol. 13 (7). Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Host-Pathogen Interactions*
Viral Envelope Proteins*/genetics
Viral Envelope Proteins*/immunology
Membrane Proteins/*genetics
Virion/*metabolism
Viruses/*metabolism
HEK293 Cells ; HIV-1/metabolism ; Humans ; Leukemia Virus, Murine/metabolism ; Membrane Proteins/immunology ; Retroviridae/classification ; Retroviridae/metabolism ; Virion/genetics ; Virus Internalization ; Viruses/chemistry ; Viruses/classification ; Viruses/genetics
Czasopismo naukowe
Tytuł :
The architecture of the SARS-CoV-2 RNA genome inside virion.
Autorzy :
Cao C; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Cai Z; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Xiao X; National Health Commission of the People's Republic of China Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Rao J; National Health Commission of the People's Republic of China Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Chen J; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Hu N; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Yang M; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xing X; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Wang Y; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Li M; School of Life Sciences, Henan Normal University, Xinxiang, China.
Zhou B; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.
Wang X; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Wang J; National Health Commission of the People's Republic of China Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. .; Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .
Xue Y; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. .; University of Chinese Academy of Sciences, Beijing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 24; Vol. 12 (1), pp. 3917. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*pathology
RNA, Viral/*chemistry
SARS-CoV-2/*genetics
Sequence Analysis, RNA/*methods
Virion/*genetics
Animals ; COVID-19/genetics ; COVID-19/virology ; Cells, Cultured ; Chlorocebus aethiops ; Genome, Viral ; Humans ; Nucleic Acid Conformation ; RNA, Viral/genetics ; SARS-CoV-2/isolation & purification ; SARS-CoV-2/pathogenicity ; Virion/chemistry ; Virion/metabolism
Czasopismo naukowe
Tytuł :
A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses.
Autorzy :
Hardy JM; Infection and Immunity Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.
Newton ND; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Modhiran N; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Scott CAP; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Venugopal H; Ramaciotti Centre for Cryo-Electron Microscopy, Monash University, Clayton, VIC, Australia.
Vet LJ; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Young PR; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Hall RA; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Hobson-Peters J; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Coulibaly F; Infection and Immunity Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia. .
Watterson D; Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 01; Vol. 12 (1), pp. 3266. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Flavivirus/*ultrastructure
Flavivirus Infections/*therapy
Viral Envelope Proteins/*ultrastructure
Virion/*ultrastructure
Aedes/virology ; Animals ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Cell Line ; Chlorocebus aethiops ; Cryoelectron Microscopy ; Dengue/therapy ; Dengue/virology ; Dengue Vaccines/administration & dosage ; Dengue Vaccines/pharmacology ; Drug Design ; Flavivirus/drug effects ; Flavivirus/immunology ; Flavivirus/pathogenicity ; Flavivirus Infections/virology ; Humans ; Mesocricetus ; Models, Molecular ; Molecular Conformation ; Mutagenesis, Site-Directed ; Point Mutation ; Vero Cells ; Viral Envelope Proteins/metabolism ; Viral Vaccines/pharmacology ; Viral Vaccines/therapeutic use ; Virion/drug effects ; Virion/metabolism
Czasopismo naukowe
Tytuł :
Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.
Autorzy :
Zhang C; Joint Center for Infection and Immunity, Guangzhou Institute of Pediatrics, Department of Gastroenterology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Xu C; State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Dai W; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Wang Y; State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Liu Z; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Zhang X; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Wang X; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Wang H; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Gong S; Joint Center for Infection and Immunity, Guangzhou Institute of Pediatrics, Department of Gastroenterology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. .
Cong Y; State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. .; Shanghai Science Research Center, Chinese Academy of Sciences, Shanghai, China. .
Huang Z; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. .
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Źródło :
Nature communications [Nat Commun] 2021 May 18; Vol. 12 (1), pp. 2904. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*immunology
Enterovirus D, Human/*immunology
Enterovirus Infections/*immunology
Virion/*immunology
Animals ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/metabolism ; Antibodies, Neutralizing/administration & dosage ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/metabolism ; Cell Line, Tumor ; Cryoelectron Microscopy ; Enterovirus D, Human/drug effects ; Enterovirus D, Human/physiology ; Enterovirus Infections/drug therapy ; Enterovirus Infections/virology ; Female ; Humans ; Mice, Inbred BALB C ; Protein Binding/drug effects ; Receptors, Cell Surface/immunology ; Receptors, Cell Surface/metabolism ; Time-to-Treatment ; Treatment Outcome ; Virion/drug effects ; Virion/metabolism ; Virion/ultrastructure ; Virus Uncoating/drug effects
Czasopismo naukowe
Tytuł :
Molecular exclusion limits for diffusion across a porous capsid.
Autorzy :
Selivanovitch E; Department of Chemistry, Indiana University, Bloomington, IN, USA.
LaFrance B; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Douglas T; Department of Chemistry, Indiana University, Bloomington, IN, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 May 18; Vol. 12 (1), pp. 2903. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Bacteriophage P22/*metabolism
Capsid/*metabolism
Capsid Proteins/*metabolism
Virion/*metabolism
Algorithms ; Bacteriophage P22/genetics ; Bacteriophage P22/ultrastructure ; Capsid/ultrastructure ; Capsid Proteins/genetics ; Cryoelectron Microscopy ; Dendrimers/chemistry ; Dendrimers/metabolism ; Diffusion ; Microscopy, Electron, Transmission ; Models, Theoretical ; Mutation ; NAD/chemistry ; NAD/metabolism ; Particle Size ; Porosity ; Static Electricity ; Virion/genetics ; Virion/ultrastructure
Czasopismo naukowe
Tytuł :
The shape of pleomorphic virions determines resistance to cell-entry pressure.
Autorzy :
Li T; Biochemistry Department, Brandeis University, Waltham, MA, USA.
Li Z; Biochemistry Department, Brandeis University, Waltham, MA, USA.
Deans EE; Biochemistry Department, Brandeis University, Waltham, MA, USA.
Mittler E; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA.
Liu M; Biochemistry Department, Brandeis University, Waltham, MA, USA.
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA.
Ivanovic T; Biochemistry Department, Brandeis University, Waltham, MA, USA. .
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Źródło :
Nature microbiology [Nat Microbiol] 2021 May; Vol. 6 (5), pp. 617-629. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Virus Attachment*
Influenza A virus/*physiology
Influenza, Human/*virology
Viral Envelope Proteins/*chemistry
Virion/*physiology
Cell Line ; Humans ; Influenza A virus/chemistry ; Influenza A virus/ultrastructure ; Viral Envelope Proteins/metabolism ; Virion/chemistry ; Virion/ultrastructure
Czasopismo naukowe
Tytuł :
Surface Plasmon Resonance (SPR)- and Localized SPR (LSPR)-Based Virus Sensing Systems: Optical Vibration of Nano- and Micro-Metallic Materials for the Development of Next-Generation Virus Detection Technology.
Autorzy :
Takemura K; Sensing System Research Center, The National Institute of Advanced Industrial Science and Technology, 07-1 Shuku-Machi, Tosu 841-0052, Japan.
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Źródło :
Biosensors [Biosensors (Basel)] 2021 Jul 26; Vol. 11 (8). Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Metal Nanoparticles/*chemistry
SARS-CoV-2/*physiology
Surface Plasmon Resonance/*methods
Virion/*isolation & purification
COVID-19/diagnosis ; COVID-19/virology ; Dengue Virus/isolation & purification ; Dengue Virus/physiology ; Humans ; Limit of Detection ; Orthomyxoviridae/isolation & purification ; Orthomyxoviridae/physiology ; Point-of-Care Systems ; SARS-CoV-2/isolation & purification ; Virion/chemistry
Czasopismo naukowe
Tytuł :
CAR Macrophages for SARS-CoV-2 Immunotherapy.
Autorzy :
Fu W; Department of Biophysics, College of Basic Medical Sciences, Second Military Medical University, Shanghai, China.; Team SMMU-China of the International Genetically Engineered Machine (iGEM) Competition, Department of Biophysics, Second Military Medical University, Shanghai, China.; Department of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lei C; Department of Biophysics, College of Basic Medical Sciences, Second Military Medical University, Shanghai, China.; Team SMMU-China of the International Genetically Engineered Machine (iGEM) Competition, Department of Biophysics, Second Military Medical University, Shanghai, China.
Ma Z; Department of Biophysics, College of Basic Medical Sciences, Second Military Medical University, Shanghai, China.
Qian K; Team SMMU-China of the International Genetically Engineered Machine (iGEM) Competition, Department of Biophysics, Second Military Medical University, Shanghai, China.
Li T; Department of Biophysics, College of Basic Medical Sciences, Second Military Medical University, Shanghai, China.; Team SMMU-China of the International Genetically Engineered Machine (iGEM) Competition, Department of Biophysics, Second Military Medical University, Shanghai, China.
Zhao J; KOCHKOR Biotech, Inc., Shanghai, China.
Hu S; Department of Biophysics, College of Basic Medical Sciences, Second Military Medical University, Shanghai, China.; Team SMMU-China of the International Genetically Engineered Machine (iGEM) Competition, Department of Biophysics, Second Military Medical University, Shanghai, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Jul 23; Vol. 12, pp. 669103. Date of Electronic Publication: 2021 Jul 23 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunotherapy, Adoptive*
COVID-19/*drug therapy
COVID-19/*immunology
Macrophages/*immunology
SARS-CoV-2/*immunology
Virion/*immunology
Animals ; COVID-19/genetics ; Chlorocebus aethiops ; Humans ; Phagocytosis ; SARS-CoV-2/genetics ; THP-1 Cells ; Vero Cells ; Virion/genetics
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Structural plasticity of mumps virus nucleocapsids with cryo-EM structures.
Autorzy :
Shan H; iHuman Institute and School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
Su X; iHuman Institute and School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Li T; iHuman Institute and School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Qin Y; iHuman Institute and School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Zhang N; iHuman Institute and School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China.
Yang L; State Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao, China.; College of Marine Life Sciences, Ocean University of China, Qingdao, China.
Ma L; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Bai Y; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Qi L; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
Liu Y; iHuman Institute and School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Shen QT; iHuman Institute and School of Life Science and Technology, ShanghaiTech University, Shanghai, China. .; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China. .
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Źródło :
Communications biology [Commun Biol] 2021 Jul 02; Vol. 4 (1), pp. 833. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cryoelectron Microscopy/*methods
Mumps virus/*metabolism
Nucleocapsid/*ultrastructure
Nucleoproteins/*ultrastructure
Viral Proteins/*ultrastructure
Virion/*metabolism
Humans ; Models, Molecular ; Mumps virus/genetics ; Nucleic Acid Conformation ; Nucleocapsid/chemistry ; Nucleoproteins/chemistry ; Protein Conformation ; RNA, Viral/chemistry ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Viral Proteins/chemistry ; Virion/genetics
Czasopismo naukowe
Tytuł :
Atomic force microscopy analysis of native infectious and inactivated SARS-CoV-2 virions.
Autorzy :
Lyonnais S; CEMIPAI, University of Montpellier, UAR3725 CNRS, Montpellier, France. .
Hénaut M; CEMIPAI, University of Montpellier, UAR3725 CNRS, Montpellier, France.
Neyret A; CEMIPAI, University of Montpellier, UAR3725 CNRS, Montpellier, France.
Merida P; Institute of Research in Infectiology of Montpellier (IRIM), University of Montpellier, UMR9004 CNRS, Montpellier, France.
Cazevieille C; Institut des Neurosciences de Montpellier (INM), Université de Montpellier, Montpellier, France.
Gros N; CEMIPAI, University of Montpellier, UAR3725 CNRS, Montpellier, France.
Chable-Bessia C; CEMIPAI, University of Montpellier, UAR3725 CNRS, Montpellier, France.
Muriaux D; CEMIPAI, University of Montpellier, UAR3725 CNRS, Montpellier, France. .; Institute of Research in Infectiology of Montpellier (IRIM), University of Montpellier, UMR9004 CNRS, Montpellier, France. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jun 04; Vol. 11 (1), pp. 11885. Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Microscopy, Atomic Force*
COVID-19/*virology
SARS-CoV-2/*ultrastructure
Virion/*ultrastructure
Animals ; Chlorocebus aethiops ; Humans ; SARS-CoV-2/physiology ; Vero Cells ; Virion/physiology ; Virus Inactivation
Czasopismo naukowe
Tytuł :
Human cardiosphere-derived stromal cells exposed to SARS-CoV-2 evolve into hyper-inflammatory/pro-fibrotic phenotype and produce infective viral particles depending on the levels of ACE2 receptor expression.
Autorzy :
Amendola A; Istituto Nazionale per le Malattie Infettive, Lazzaro Spallanzani, IRCCS, Rome, Italy.
Garoffolo G; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.; DIMET Ph.D. program, Università di Milano-Bicocca, Italy.
Songia P; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.
Nardacci R; Istituto Nazionale per le Malattie Infettive, Lazzaro Spallanzani, IRCCS, Rome, Italy.
Ferrari S; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.; Ph.D. program in Translational Medicine, Università degli studi di Pavia, Italy.
Bernava G; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.
Canzano P; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.
Myasoedova V; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.
Colavita F; Istituto Nazionale per le Malattie Infettive, Lazzaro Spallanzani, IRCCS, Rome, Italy.
Castilletti C; Istituto Nazionale per le Malattie Infettive, Lazzaro Spallanzani, IRCCS, Rome, Italy.
Sberna G; Istituto Nazionale per le Malattie Infettive, Lazzaro Spallanzani, IRCCS, Rome, Italy.
Capobianchi MR; Istituto Nazionale per le Malattie Infettive, Lazzaro Spallanzani, IRCCS, Rome, Italy.
Piacentini M; Università degli studi di Roma 'Tor Vergata', Rome, Italy.
Agrifoglio M; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.; Università degli studi di Milano, Milan, Italy.
Colombo GI; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.
Poggio P; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.
Pesce M; Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, Milan, Italy.
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Źródło :
Cardiovascular research [Cardiovasc Res] 2021 May 25; Vol. 117 (6), pp. 1557-1566.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin-Converting Enzyme 2/*metabolism
COVID-19/*virology
Heart Diseases/*virology
Myocardium/*enzymology
Receptors, Virus/*metabolism
SARS-CoV-2/*pathogenicity
Stromal Cells/*virology
Virion/*pathogenicity
Aged ; Aged, 80 and over ; Angiotensin-Converting Enzyme 2/genetics ; Animals ; COVID-19/complications ; Chlorocebus aethiops ; Female ; Fibrosis ; Heart Diseases/enzymology ; Heart Diseases/pathology ; Host-Pathogen Interactions ; Humans ; Inflammation Mediators/metabolism ; Male ; Middle Aged ; Myocardium/ultrastructure ; Phenotype ; Receptors, Virus/genetics ; SARS-CoV-2/ultrastructure ; Spheroids, Cellular ; Stromal Cells/enzymology ; Stromal Cells/ultrastructure ; Vero Cells ; Virion/ultrastructure
Czasopismo naukowe
Tytuł :
Chemodynamic features of nanoparticles: Application to understanding the dynamic life cycle of SARS-CoV-2 in aerosols and aqueous biointerfacial zones.
Autorzy :
Duval JFL; Université de Lorraine, CNRS, LIEC, F-54000 Nancy, France.
van Leeuwen HP; Physical Chemistry and Soft Matter, Wageningen University & Research, Stippeneng 4, 6708, WE, Wageningen, the Netherlands.
Norde W; Physical Chemistry and Soft Matter, Wageningen University & Research, Stippeneng 4, 6708, WE, Wageningen, the Netherlands.
Town RM; Physical Chemistry and Soft Matter, Wageningen University & Research, Stippeneng 4, 6708, WE, Wageningen, the Netherlands; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, Universiteit Antwerpen, Groenenborgerlaan 171, 2020 Antwerpen, Belgium.. Electronic address: .
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Źródło :
Advances in colloid and interface science [Adv Colloid Interface Sci] 2021 Apr; Vol. 290, pp. 102400. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*transmission
Epithelial Cells/*virology
Particulate Matter/*chemistry
SARS-CoV-2/*chemistry
Virion/*chemistry
Aerosols ; Biomechanical Phenomena ; COVID-19/virology ; Diffusion ; Humans ; Hydrophobic and Hydrophilic Interactions ; Models, Chemical ; Nanoparticles/chemistry ; Pulmonary Alveoli/virology ; SARS-CoV-2/metabolism ; SARS-CoV-2/pathogenicity ; Static Electricity ; Virion/metabolism ; Virion/pathogenicity ; Virus Internalization ; Water/chemistry
Czasopismo naukowe
Tytuł :
Effect of Inactivation Methods on SARS-CoV-2 Virion Protein and Structure.
Autorzy :
Loveday EK; Department of Chemical & Biological Engineering, Montana State University, Bozeman, MT 59717, USA.
Hain KS; Department of Microbiology & Immunology, Montana State University, Bozeman, MT 59717, USA.
Kochetkova I; Department of Microbiology & Immunology, Montana State University, Bozeman, MT 59717, USA.
Hedges JF; Department of Microbiology & Immunology, Montana State University, Bozeman, MT 59717, USA.
Robison A; Department of Microbiology & Immunology, Montana State University, Bozeman, MT 59717, USA.
Snyder DT; Department of Microbiology & Immunology, Montana State University, Bozeman, MT 59717, USA.
Brumfield SK; Department of Plant Science and Plant Pathology, Montana State University; Bozeman, MT 59717, USA.
Young MJ; Department of Plant Science and Plant Pathology, Montana State University; Bozeman, MT 59717, USA.
Jutila MA; Department of Microbiology & Immunology, Montana State University, Bozeman, MT 59717, USA.
Chang CB; Department of Chemical & Biological Engineering, Montana State University, Bozeman, MT 59717, USA.
Taylor MP; Department of Microbiology & Immunology, Montana State University, Bozeman, MT 59717, USA.
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Źródło :
Viruses [Viruses] 2021 Mar 26; Vol. 13 (4). Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*virology
Disinfection/*methods
SARS-CoV-2/*radiation effects
Virion/*radiation effects
Virus Inactivation/*radiation effects
Disinfection/instrumentation ; Hot Temperature ; Humans ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology ; Ultraviolet Rays ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Virion/chemistry ; Virion/genetics ; Virion/physiology
Czasopismo naukowe

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