ETC-159, an Upstream Wnt inhibitor, Induces Tumour Necrosis via Modulation of Angiogenesis in Osteosarcoma.
Autorzy:
Chua K; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore.; Department of Orthopaedic Surgery, Singapore General Hospital, Singapore 169608, Singapore.; Programme in Musculoskeletal Sciences Academic Clinical Program, SingHealth/Duke-NUS, Singapore 169857, Singapore. Sim AYL; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Level 3 NUH Main Building, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. Yeo EYM; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Level 3 NUH Main Building, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. Bin Masroni MS; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Level 3 NUH Main Building, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. Naw WW; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Level 3 NUH Main Building, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. Leong SM; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Level 3 NUH Main Building, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. Lee KW; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, MD10, 4 Medical Drive, Singapore 117594, Singapore. Lim HJ; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Level 3 NUH Main Building, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. VirshupDM; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore. Lee VKM; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Level 3 NUH Main Building, 5 Lower Kent Ridge Road, Singapore 119074, Singapore.
Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation.
Autorzy:
Liu S; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, Singapore. Harmston N; Science Division, Yale-NUS College, Singapore, Singapore. Glaser TL; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore. Wong Y; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore. Zhong Z; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore. Madan B; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore. VirshupDM; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore. david.virshup@duke-nus.edu.sg.; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina, USA. david.virshup@duke-nus.edu.sg. Petretto E; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, Singapore. .; MRC London Institute of Medical Sciences, Imperial College London, London, UK. .
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Źródło:
Genome medicine [Genome Med] 2020 Oct 22; Vol. 12 (1), pp. 89. Date of Electronic Publication: 2020 Oct 22.
A Ras-LSD1 axis activates PI3K signaling through PIK3IP1 suppression.
Autorzy:
Lee K; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore. .; Prestige Biopharma Pte Ltd, Singapore, 117543, Singapore. . Kitagawa M; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.; MK, Daiichi Sankyo Co., Tokyo, 103-8426, Japan. Liao PJ; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore. VirshupDM; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore. david.virshup@duke-nus.edu.sg.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, 27710, USA. david.virshup@duke-nus.edu.sg. Lee SH; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, 169857, Singapore.
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Źródło:
Oncogenesis [Oncogenesis] 2020 Jan 02; Vol. 9 (1), pp. 2. Date of Electronic Publication: 2020 Jan 02.
Wnt traffic from endoplasmic reticulum to filopodia.
Autorzy:
Moti N; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore. Yu J; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore. Boncompain G; Institut Curie, PSL Research University, Sorbonne Université, CNRS UMR144 'Cell Biology and Cancer', Paris, France. Perez F; Institut Curie, PSL Research University, Sorbonne Université, CNRS UMR144 'Cell Biology and Cancer', Paris, France. VirshupDM; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore.; Department of Pediatrics, Duke University, Durham, North Carolina, United States of America.
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Źródło:
PloS one [PLoS One] 2019 Feb 22; Vol. 14 (2), pp. e0212711. Date of Electronic Publication: 2019 Feb 22 (Print Publication: 2019).
Site-specific phosphorylation of casein kinase 1 δ (CK1δ) regulates its activity towards the circadian regulator PER2.
Autorzy:
Eng GWL; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore. Edison; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore. VirshupDM; Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina, United States of America.
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Źródło:
PloS one [PLoS One] 2017 May 17; Vol. 12 (5), pp. e0177834. Date of Electronic Publication: 2017 May 17 (Print Publication: 2017).
Cheong JK; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School , Singapore. VirshupDM; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School , Singapore.
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Źródło:
Molecular & cellular oncology [Mol Cell Oncol] 2015 May 26; Vol. 3 (3), pp. e1045117. Date of Electronic Publication: 2015 May 26 (Print Publication: 2016).
Casein kinase 1 regulates Sprouty2 in FGF-ERK signaling.
Autorzy:
Yim DG; 1] Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore [2] Signal Transduction Laboratory, Institute for Molecular and Cellular Biology, Biopolis, Singapore [3] Genome Institute of Singapore, Biopolis, Singapore. Ghosh S; Center for Computational Biology, Duke-NUS Graduate Medical School, Singapore, Singapore. Guy GR; Signal Transduction Laboratory, Institute for Molecular and Cellular Biology, Biopolis, Singapore. VirshupDM; 1] Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore [2] Department of Biochemistry, YYL School of Medicine, National University of Singapore, Singapore, Singapore.
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Źródło:
Oncogene [Oncogene] 2015 Jan 22; Vol. 34 (4), pp. 474-84. Date of Electronic Publication: 2014 Jan 27.
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