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Tytuł :
Classical swine fever virus employs the PERK- and IRE1-dependent autophagy for viral replication in cultured cells.
Autorzy :
Zhu E; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.; Department of Veterinary Medicine, College of Animal Science, Guizhou University , Guiyang, China.
Wu H; Department of Viral Biologics, China Institute of Veterinary Drug Control , Beijing, China.
Chen W; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Qin Y; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Liu J; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Fan S; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Ma S; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Wu K; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Mao Q; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Luo C; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Qin Y; Department of Viral Biologics, China Institute of Veterinary Drug Control , Beijing, China.
Yi L; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Ding H; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Zhao M; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
Chen J; Department of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture , Guangzhou, China.
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Źródło :
Virulence [Virulence] 2021 Dec; Vol. 12 (1), pp. 130-149.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autophagy*
Cell Survival*
Virus Replication*
Classical Swine Fever Virus/*genetics
Classical Swine Fever Virus/*physiology
Endoribonucleases/*metabolism
eIF-2 Kinase/*metabolism
Animals ; Cell Line ; Classical Swine Fever Virus/immunology ; Classical Swine Fever Virus/pathogenicity ; Cytokines/immunology ; Endoplasmic Reticulum Stress ; Endoribonucleases/genetics ; RNA, Small Interfering ; Signal Transduction ; Swine ; eIF-2 Kinase/genetics
Czasopismo naukowe
Tytuł :
Targeting conserved co-opted host factors to block virus replication: Using allosteric inhibitors of the cytosolic Hsp70s to interfere with tomato bushy stunt virus replication.
Autorzy :
Molho M; Department of Plant Pathology, University of Kentucky, Lexington, KY, 40546, USA.
Prasanth KR; Department of Plant Pathology, University of Kentucky, Lexington, KY, 40546, USA.
Pogany J; Department of Plant Pathology, University of Kentucky, Lexington, KY, 40546, USA.
Nagy PD; Department of Plant Pathology, University of Kentucky, Lexington, KY, 40546, USA. Electronic address: .
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Źródło :
Virology [Virology] 2021 Nov; Vol. 563, pp. 1-19. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Arabidopsis/*metabolism
HSP70 Heat-Shock Proteins/*metabolism
Tombusvirus/*physiology
Virus Replication/*physiology
Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Benzothiazoles/pharmacology ; Gene Expression Regulation, Plant/immunology ; Gene Expression Regulation, Viral/drug effects ; Gene Expression Regulation, Viral/physiology ; Gene Knockdown Techniques ; Genetic Complementation Test ; HSP70 Heat-Shock Proteins/genetics ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Plant Leaves/metabolism ; Plant Leaves/virology ; Pyridinium Compounds/pharmacology ; RNA, Viral/physiology ; Tobacco/metabolism ; Tobacco/virology ; Two-Hybrid System Techniques ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Marek's disease virus encoded miR-M6 and miR-M10 are dispensable for virus replication and pathogenesis in chickens.
Autorzy :
Yang S; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China.
Liao Y; Division of Infectious Disease, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Zhang S; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China.
Lu W; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China.
Jin J; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China.
Teng M; Key Laboratory of Animal Immunology, Ministry of Agriculture and Rural Affairs & Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, People's Republic of China; UK-China Centre of Excellence for Research on Avian Diseases, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, People's Republic of China.
Chai S; Key Laboratory of Animal Immunology, Ministry of Agriculture and Rural Affairs & Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, People's Republic of China.
Luo J; Key Laboratory of Animal Immunology, Ministry of Agriculture and Rural Affairs & Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, People's Republic of China; UK-China Centre of Excellence for Research on Avian Diseases, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, People's Republic of China.
Zhang G; Key Laboratory of Animal Immunology, Ministry of Agriculture and Rural Affairs & Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, People's Republic of China; UK-China Centre of Excellence for Research on Avian Diseases, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, People's Republic of China; Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou University, Yangzhou, 225009, People's Republic of China.
Sun A; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China. Electronic address: .
Zhuang G; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2021 Nov; Vol. 262, pp. 109248. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article
MeSH Terms :
Herpesvirus 2, Gallid*/genetics
Marek Disease*/physiopathology
Marek Disease*/virology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Virus Replication*/genetics
Animals ; Cells, Cultured ; Chickens
Czasopismo naukowe
Tytuł :
Synthesis and In Vitro Study of Antiviral Activity of Glycyrrhizin Nicotinate Derivatives against HIV-1 Pseudoviruses and SARS-CoV-2 Viruses.
Autorzy :
Fomenko VV; Department of Medicinal Chemistry, N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentiev Ave. 9, 630090 Novosibirsk, Russia.
Rudometova NB; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia.
Yarovaya OI; Department of Medicinal Chemistry, N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentiev Ave. 9, 630090 Novosibirsk, Russia.; Zelman Institute for Medicine and Psychology, Novosibirsk State University, Pirogov Str. 1, 630090 Novosibirsk, Russia.
Rogachev AD; Department of Medicinal Chemistry, N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentiev Ave. 9, 630090 Novosibirsk, Russia.; Zelman Institute for Medicine and Psychology, Novosibirsk State University, Pirogov Str. 1, 630090 Novosibirsk, Russia.
Fando AA; Zelman Institute for Medicine and Psychology, Novosibirsk State University, Pirogov Str. 1, 630090 Novosibirsk, Russia.
Zaykovskaya AV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia.
Komarova NI; Department of Medicinal Chemistry, N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentiev Ave. 9, 630090 Novosibirsk, Russia.
Shcherbakov DN; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia.
Pyankov OV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia.
Pokrovsky AG; Zelman Institute for Medicine and Psychology, Novosibirsk State University, Pirogov Str. 1, 630090 Novosibirsk, Russia.
Karpenko LI; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia.
Maksyutov RA; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia.
Salakhutdinov NF; Department of Medicinal Chemistry, N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrentiev Ave. 9, 630090 Novosibirsk, Russia.; Zelman Institute for Medicine and Psychology, Novosibirsk State University, Pirogov Str. 1, 630090 Novosibirsk, Russia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2022 Jan 04; Vol. 27 (1). Date of Electronic Publication: 2022 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Virus Replication*
Antiviral Agents/*pharmacology
COVID-19/*drug therapy
Glycyrrhizic Acid/*chemistry
HIV Infections/*drug therapy
HIV-1/*drug effects
SARS-CoV-2/*drug effects
Animals ; Antiviral Agents/chemical synthesis ; COVID-19/virology ; Chlorocebus aethiops ; HIV Infections/virology ; HeLa Cells ; Humans ; In Vitro Techniques ; Vero Cells
Czasopismo naukowe
Tytuł :
Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans.
Autorzy :
Zickler M; Leibniz Institute for Experimental Virology, Hamburg, Germany.
Stanelle-Bertram S; Leibniz Institute for Experimental Virology, Hamburg, Germany.
Ehret S; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Heinrich F; Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Lange P; Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Schaumburg B; Leibniz Institute for Experimental Virology, Hamburg, Germany.
Kouassi NM; Leibniz Institute for Experimental Virology, Hamburg, Germany.
Beck S; Leibniz Institute for Experimental Virology, Hamburg, Germany.
Jaeckstein MY; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Mann O; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Krasemann S; Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany.
Schroeder M; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jarczak D; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nierhaus A; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Kluge S; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Peschka M; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Schlüter H; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Renné T; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Pueschel K; Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Kloetgen A; Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Scheja L; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ondruschka B; Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Heeren J; Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: .
Gabriel G; Leibniz Institute for Experimental Virology, Hamburg, Germany; Institute for Virology, University for Veterinary Medicine Hanover, Hanover, Germany. Electronic address: .
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Źródło :
Cell metabolism [Cell Metab] 2022 Jan 04; Vol. 34 (1), pp. 1-2. Date of Electronic Publication: 2021 Dec 10.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipid Metabolism*
Virus Replication*
Adipose Tissue/*metabolism
COVID-19/*virology
Liver/*metabolism
Lung/*metabolism
SARS-CoV-2/*isolation & purification
Adipose Tissue/virology ; Animals ; COVID-19/metabolism ; Cricetinae ; Female ; Humans ; Liver/virology ; Lung/virology ; Male
Raport
Tytuł :
Swine acute diarrhea syndrome coronavirus replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway.
Autorzy :
Zhang J; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Zhang L; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Shi H; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Feng S; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Feng T; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Chen J; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Zhang X; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Han Y; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Liu J; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Wang Y; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Ji Z; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Jing Z; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Liu D; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China.
Shi D; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China. Electronic address: .
Feng L; State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xiangfang District, Haping Road 678, Harbin, 150069, China. Electronic address: .
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Źródło :
Virology [Virology] 2022 Jan 02; Vol. 565, pp. 96-105. Date of Electronic Publication: 2021 Oct 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
MAP Kinase Signaling System*/drug effects
Virus Replication*/drug effects
Alphacoronavirus/*physiology
Mitogen-Activated Protein Kinase 1/*metabolism
Mitogen-Activated Protein Kinase 3/*metabolism
Animals ; Apoptosis/drug effects ; Cell Line ; Cell Nucleus/metabolism ; Chlorocebus aethiops ; Gene Knockdown Techniques ; Host-Pathogen Interactions ; Mitogen-Activated Protein Kinase 1/antagonists & inhibitors ; Mitogen-Activated Protein Kinase 1/genetics ; Mitogen-Activated Protein Kinase 3/antagonists & inhibitors ; Mitogen-Activated Protein Kinase 3/genetics ; Protein Kinase Inhibitors/pharmacology ; Swine ; Vero Cells
SCR Organism :
Swine acute diarrhea syndrome coronavirus
Czasopismo naukowe
Tytuł :
NS1 protein as a novel anti-influenza target: Map-and-mutate antiviral rationale reveals new putative druggable hot spots with an important role on viral replication.
Autorzy :
Trigueiro-Louro J; Host-Pathogen Interaction Unit, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Professor Gama Pinto, 1649-003, Lisbon, Portugal; Antiviral Resistance Lab, Research & Development Unit, Infectious Diseases Department, Instituto Nacional de Saúde Doutor Ricardo Jorge, IP, Av. Padre Cruz, 1649-016, Lisbon, Portugal. Electronic address: .
Santos LA; Antiviral Resistance Lab, Research & Development Unit, Infectious Diseases Department, Instituto Nacional de Saúde Doutor Ricardo Jorge, IP, Av. Padre Cruz, 1649-016, Lisbon, Portugal.
Almeida F; Host-Pathogen Interaction Unit, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Professor Gama Pinto, 1649-003, Lisbon, Portugal; Antiviral Resistance Lab, Research & Development Unit, Infectious Diseases Department, Instituto Nacional de Saúde Doutor Ricardo Jorge, IP, Av. Padre Cruz, 1649-016, Lisbon, Portugal.
Correia V; Antiviral Resistance Lab, Research & Development Unit, Infectious Diseases Department, Instituto Nacional de Saúde Doutor Ricardo Jorge, IP, Av. Padre Cruz, 1649-016, Lisbon, Portugal.
Brito RMM; Chemistry Department and Coimbra Chemistry Centre, Faculty of Science and Technology, University of Coimbra, 3004-535, Coimbra, Portugal.
Rebelo-de-Andrade H; Host-Pathogen Interaction Unit, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Professor Gama Pinto, 1649-003, Lisbon, Portugal; Antiviral Resistance Lab, Research & Development Unit, Infectious Diseases Department, Instituto Nacional de Saúde Doutor Ricardo Jorge, IP, Av. Padre Cruz, 1649-016, Lisbon, Portugal. Electronic address: .
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Źródło :
Virology [Virology] 2022 Jan 02; Vol. 565, pp. 106-116. Date of Electronic Publication: 2021 Nov 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Replication*
Influenza A virus/*genetics
Influenza A virus/*pathogenicity
Influenza, Human/*virology
Orthomyxoviridae Infections/*virology
Viral Nonstructural Proteins/*genetics
Amino Acid Substitution ; Animals ; Apoptosis ; Cell Line ; Dogs ; Drug Discovery ; HEK293 Cells ; Host Microbial Interactions ; Humans ; Influenza, Human/metabolism ; Madin Darby Canine Kidney Cells ; Mutation ; Orthomyxoviridae Infections/metabolism
Czasopismo naukowe
Tytuł :
Replication of Streptococcus equi subspecies zooepidemicus infection in swine.
Autorzy :
Hau SJ; Virus and Prion Research Unit, National Animal Disease Center, ARS, USDA, Ames, IA, United States.
Lantz K; National Veterinary Services Laboratories, APHIS, USDA, Ames, IA, United States.
Stuart KL; National Veterinary Services Laboratories, APHIS, USDA, Ames, IA, United States.
Sitthicharoenchai P; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.
Macedo N; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.
Derscheid RJ; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.
Burrough ER; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.
Robbe-Austerman S; National Veterinary Services Laboratories, APHIS, USDA, Ames, IA, United States.
Brockmeier SL; Virus and Prion Research Unit, National Animal Disease Center, ARS, USDA, Ames, IA, United States. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2022 Jan; Vol. 264, pp. 109271. Date of Electronic Publication: 2021 Nov 02.
Typ publikacji :
Journal Article
MeSH Terms :
Horse Diseases*/virology
Streptococcal Infections*/veterinary
Streptococcal Infections*/virology
Streptococcus equi*/physiology
Swine Diseases*/virology
Virus Replication*/physiology
Animals ; Disease Models, Animal ; Female ; Guinea Pigs ; Horses ; Swine
Czasopismo naukowe
Tytuł :
Hepatitis E virus-encoded microRNA promotes viral replication by inhibiting type I interferon.
Autorzy :
Qian Z; Medical School, Kunming University of Science and Technology, Kunming, PR China.
Yang C; Medical School, Kunming University of Science and Technology, Kunming, PR China.
Xu L; Medical School, Kunming University of Science and Technology, Kunming, PR China.
Mickael HK; Medical School, Kunming University of Science and Technology, Kunming, PR China.
Chen S; Medical School, Kunming University of Science and Technology, Kunming, PR China.
Zhang Y; Medical School, Kunming University of Science and Technology, Kunming, PR China.
Xia Y; Medical School, Kunming University of Science and Technology, Kunming, PR China.
Li T; Medical School, Kunming University of Science and Technology, Kunming, PR China.
Yu W; Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, PR China.
Huang F; Medical School, Kunming University of Science and Technology, Kunming, PR China.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2022 Jan; Vol. 36 (1), pp. e22104.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Viral*
Virus Replication*
Hepatitis E/*metabolism
Hepatitis E virus/*physiology
Interferon-beta/*metabolism
MicroRNAs/*biosynthesis
RNA, Viral/*biosynthesis
Female ; Humans ; Male ; Organ Specificity
Czasopismo naukowe
Tytuł :
gga-miR-200b-3p promotes avian leukosis virus subgroup J replication via targeting dual-specificity phosphatase 1.
Autorzy :
Pang Y; College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China.
Yan Y; College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China.
Zhang X; College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, Guangdong 510642, PR China.
Chen F; College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, Guangdong 510642, PR China.
Luo Q; College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, Guangdong 510642, PR China.
Xie Q; College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, Guangdong 510642, PR China. Electronic address: .
Lin W; College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, Guangzhou, Guangdong 510642, PR China. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2022 Jan; Vol. 264, pp. 109278. Date of Electronic Publication: 2021 Nov 11.
Typ publikacji :
Journal Article
MeSH Terms :
Avian Leukosis*/pathology
Avian Leukosis*/virology
Avian Leukosis Virus*/enzymology
Avian Leukosis Virus*/genetics
Dual-Specificity Phosphatases*/metabolism
Host Microbial Interactions*/physiology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Virus Replication*/genetics
Animals ; Chickens
Czasopismo naukowe
Tytuł :
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication.
Autorzy :
Arena A; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
Gilardini Montani MS; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
Romeo MA; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
Benedetti R; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.
Gaeta A; Department of Molecular Medicine, 'Sapienza' University of Rome, Rome, Italy.
Cirone M; Department of Experimental Medicine, 'Sapienza' University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Rome, Italy.. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2022 Jan; Vol. 1869 (1), pp. 119168. Date of Electronic Publication: 2021 Oct 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
DNA Damage*
Virus Replication*
Lymphoma, Primary Effusion/*metabolism
Proto-Oncogene Proteins c-myc/*metabolism
Tumor Suppressor Protein p53/*metabolism
Cell Line ; Cells, Cultured ; Checkpoint Kinase 1/antagonists & inhibitors ; Checkpoint Kinase 1/metabolism ; Herpesvirus 8, Human/physiology ; Humans ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Lymphoma, Primary Effusion/genetics ; Lymphoma, Primary Effusion/virology ; Phthalazines/pharmacology ; Piperidines/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/toxicity ; Protein Kinase Inhibitors/toxicity ; Staurosporine/analogs & derivatives ; Staurosporine/pharmacology
Czasopismo naukowe
Tytuł :
DDX56 antagonizes IFN-β production to enhance EMCV replication by inhibiting IRF3 nuclear translocation.
Autorzy :
Xu S; Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Xie J; Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Zhang X; Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Chen L; Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Bi Y; Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Li X; Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China.
Idris A; Menzies Health Institute Queensland, School of Pharmacy and Medical Science, Griffith University, Southport, Queensland, Australia.
Feng R; Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Biomedical Research Center, Northwest Minzu University, Lanzhou, China; Gansu Tech Innovation Center of Animal Cell, Biomedical Research Center, Northwest Minzu University, Lanzhou, China. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2022 Jan; Vol. 264, pp. 109304. Date of Electronic Publication: 2021 Dec 13.
Typ publikacji :
Journal Article
MeSH Terms :
DEAD-box RNA Helicases*/metabolism
Encephalomyocarditis virus*/physiology
Host-Pathogen Interactions*/immunology
Interferon Regulatory Factor-3*/metabolism
Interferon-beta*/genetics
Interferon-beta*/metabolism
Protein Transport*
Virus Replication*/genetics
Cardiovirus Infections/physiopathology ; Cardiovirus Infections/virology ; Cell Line ; HEK293 Cells ; Humans
Czasopismo naukowe
Tytuł :
Gga-miR-29a-3p suppresses avian reovirus-induced apoptosis and viral replication via targeting Caspase-3.
Autorzy :
Zhou L; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Li J; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Haiyilati A; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Li X; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Gao L; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Cao H; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Wang Y; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China. Electronic address: .
Zheng SJ; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2022 Jan; Vol. 264, pp. 109294. Date of Electronic Publication: 2021 Nov 24.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/genetics
Caspase 3*/genetics
Caspase 3*/metabolism
MicroRNAs*/metabolism
MicroRNAs*/pharmacology
Orthoreovirus, Avian*/physiology
Virus Replication*/genetics
Animals ; Chickens
Czasopismo naukowe
Tytuł :
Molecular chaperone TRiC governs avian reovirus replication by protecting outer-capsid protein σC and inner core protein σA and non-structural protein σNS from ubiquitin- proteasome degradation.
Autorzy :
Huang WR; Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan; The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.
Li JY; Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan; The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.
Liao TL; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan; Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan; Ph.D Program in Translational Medicine, National Chung Hsing University, Taichung, 402, Taiwan.
Yeh CM; Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan; Bioproduction Reearch Institute, National Institute of Advanced Industrial Science and Technology, Tsukaba, Japan.
Wang CY; The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung, Taiwan; Department of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Wen HW; Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan.
Hu NJ; Institute of Biochemistry, National Chung Hsing University, Taichung, Taiwan.
Wu YY; Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan; The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.
Hsu CY; Ph.D Program in Translational Medicine, National Chung Hsing University, Taichung, 402, Taiwan; Division of Urology, Department of Surgery, Tung's Taichung MetroHarbor Hospital, Taichung, Taiwan.
Chang YK; Department of Medical Research, Tung's Taichung MetroHarbor Hospital, Taichung, Taiwan; Depertment of Nursing, Jen-Teh Junior College of Medicine and Management, Taiwan.
Chang CD; Department of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung, Taiwan.
Nielsen BL; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, USA.
Liu HJ; Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan; The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung, Taiwan; Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan; Ph.D Program in Translational Medicine, National Chung Hsing University, Taichung, 402, Taiwan; Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2022 Jan; Vol. 264, pp. 109277. Date of Electronic Publication: 2021 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Chaperonin Containing TCP-1*/metabolism
Orthoreovirus, Avian*/genetics
Viral Proteins*/metabolism
Virus Replication*/genetics
Animals ; Capsid Proteins/metabolism ; Proteasome Endopeptidase Complex/metabolism ; RNA-Binding Proteins/metabolism ; Ubiquitin/metabolism ; Viral Core Proteins/metabolism ; Viral Regulatory and Accessory Proteins/metabolism
Czasopismo naukowe
Tytuł :
T598 and T601 phosphorylation sites of canine parvovirus NS1 are crucial for viral replication and pathogenicity.
Autorzy :
Miao B; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Chen S; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Zhang X; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Ma P; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Ma M; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Chen C; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Zhang X; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Chang L; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Du Q; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Huang Y; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China. Electronic address: .
Tong D; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2022 Jan; Vol. 264, pp. 109301. Date of Electronic Publication: 2021 Dec 07.
Typ publikacji :
Journal Article
MeSH Terms :
Dog Diseases*/virology
Parvoviridae Infections*/veterinary
Parvoviridae Infections*/virology
Parvovirus, Canine*/genetics
Parvovirus, Canine*/pathogenicity
Virus Replication*/genetics
Animals ; Dogs ; Phosphorylation ; Phylogeny ; Virulence/genetics
Czasopismo naukowe
Tytuł :
The Betacoronavirus PHEV Replicates and Disrupts the Respiratory Epithelia and Upregulates Key Pattern Recognition Receptor Genes and Downstream Mediators, Including IL-8 and IFN-λ.
Autorzy :
Nelli RK; Veterinary Diagnostic Laboratory, Department of Veterinary Diagnostic & Production Animal Medicine, College of Veterinary Medicine, Iowa State Universitygrid.34421.30, Ames, Iowa, USA.
Mora-Díaz JC; Veterinary Diagnostic Laboratory, Department of Veterinary Diagnostic & Production Animal Medicine, College of Veterinary Medicine, Iowa State Universitygrid.34421.30, Ames, Iowa, USA.
Giménez-Lirola LG; Veterinary Diagnostic Laboratory, Department of Veterinary Diagnostic & Production Animal Medicine, College of Veterinary Medicine, Iowa State Universitygrid.34421.30, Ames, Iowa, USA.
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Źródło :
MSphere [mSphere] 2021 Dec 22; Vol. 6 (6), pp. e0082021. Date of Electronic Publication: 2021 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Virus Replication*/immunology
Betacoronavirus 1/*physiology
Interferons/*genetics
Interleukin-8/*immunology
Receptors, Pattern Recognition/*genetics
Respiratory Mucosa/*immunology
Respiratory Mucosa/*virology
Animals ; Animals, Newborn ; Betacoronavirus 1/immunology ; Coronavirus Infections/immunology ; Coronavirus Infections/virology ; Immunity, Innate/genetics ; Immunity, Innate/immunology ; Interferons/immunology ; Interleukin-8/genetics ; Respiratory Mucosa/pathology ; Swine ; Up-Regulation
Czasopismo naukowe
Tytuł :
Bacteriophage self-counting in the presence of viral replication.
Autorzy :
Yao T; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030.; Department of Physics, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Coleman S; Center for Theoretical Biological Physics, Rice University, Houston, TX 77030.; Applied Physics Graduate Program, Rice University, Houston, TX 77005.; Department of Bioengineering, Rice University, Houston, TX 77030.
Nguyen TVP; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030.; Department of Physics, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Golding I; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030; .; Department of Physics, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, IL 61801.; Center for Theoretical Biological Physics, Rice University, Houston, TX 77030.
Igoshin OA; Center for Theoretical Biological Physics, Rice University, Houston, TX 77030; .; Department of Bioengineering, Rice University, Houston, TX 77030.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Dec 21; Vol. 118 (51).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Lysogeny*
Models, Biological*
Virus Replication*
Bacteriophage lambda/*physiology
Gene Dosage ; Gene Expression Regulation, Viral ; Genome, Viral
Czasopismo naukowe
Tytuł :
Immune memory from SARS-CoV-2 infection in hamsters provides variant-independent protection but still allows virus transmission.
Autorzy :
Horiuchi S; Department of Microbiology, New York University, New York, NY 10016, USA.
Oishi K; Department of Microbiology, New York University, New York, NY 10016, USA.
Carrau L; Department of Microbiology, New York University, New York, NY 10016, USA.
Frere J; Department of Microbiology, New York University, New York, NY 10016, USA.
Møller R; Department of Microbiology, New York University, New York, NY 10016, USA.
Panis M; Department of Microbiology, New York University, New York, NY 10016, USA.
tenOever BR; Department of Microbiology, New York University, New York, NY 10016, USA.
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Źródło :
Science immunology [Sci Immunol] 2021 Dec 17; Vol. 6 (66), pp. eabm3131. Date of Electronic Publication: 2021 Dec 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
COVID-19/*immunology
Immunologic Memory/*immunology
SARS-CoV-2/*immunology
Virus Replication/*immunology
Adaptive Immunity/immunology ; Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; B-Lymphocytes/immunology ; B-Lymphocytes/virology ; COVID-19/virology ; Cricetinae ; Host-Pathogen Interactions/immunology ; Humans ; Immunity, Innate/immunology ; Mesocricetus ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology ; T-Lymphocytes/immunology ; T-Lymphocytes/virology ; Virus Replication/genetics
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Analysis of Severe Acute Respiratory Syndrome 2 Replication in Explant Cultures of the Human Upper Respiratory Tract Reveals Broad Tissue Tropism of Wild-Type and B.1.1.7 Variant Viruses.
Autorzy :
Schulze J; Unit 17 'Influenza and other Respiratory Viruses', Robert Koch Institute, Berlin, Germany.
Mache C; Unit 17 'Influenza and other Respiratory Viruses', Robert Koch Institute, Berlin, Germany.
Balázs A; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Berlin, Germany.; German Center for Lung Research (DZL), associated partner site, Berlin, Germany.
Frey D; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany.
Niemeyer D; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Institute of Virology, Berlin Institute of Health and German Centre for Infection Research, Berlin, Germany.
Olze H; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Department of Otorhinolaryngology, Berlin, Germany.
Dommerich S; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Department of Otorhinolaryngology, Berlin, Germany.
Drosten C; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Institute of Virology, Berlin Institute of Health and German Centre for Infection Research, Berlin, Germany.
Hocke AC; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany.
Mall MA; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Berlin, Germany.; German Center for Lung Research (DZL), associated partner site, Berlin, Germany.
Hippenstiel S; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany.
Wolff T; Unit 17 'Influenza and other Respiratory Viruses', Robert Koch Institute, Berlin, Germany.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2021 Dec 15; Vol. 224 (12), pp. 2020-2024.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Viral Tropism*
Virus Replication*
COVID-19/*virology
Respiratory System/*virology
Humans ; Respiratory Tract Infections ; SARS-CoV-2 ; Trachea
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe

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