Temat: "Voltage" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Neuronal Protection by Ha-RAS-GTPase Signaling through Selective Downregulation of Plasmalemmal Voltage-Dependent Anion Channel-1.
Autorzy:: Neumann S; Department of Biochemistry II-Molecular Neurobiochemistry, Faculty of Chemistry and Biochemistry, Ruhr-Universität Bochum, 44801 Bochum, Germany.
Kuteykin-Teplyakov K; Department of Biochemistry II-Molecular Neurobiochemistry, Faculty of Chemistry and Biochemistry, Ruhr-Universität Bochum, 44801 Bochum, Germany.
Heumann R; Department of Biochemistry II-Molecular Neurobiochemistry, Faculty of Chemistry and Biochemistry, Ruhr-Universität Bochum, 44801 Bochum, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:: Journal Article
MeSH Terms:: Voltage-Dependent Anion Channels*/metabolism
Neurodegenerative Diseases*/metabolism
Mice ; Animals ; Neuroprotection ; ras Proteins/metabolism ; Down-Regulation ; Voltage-Dependent Anion Channel 1/metabolism ; Cell Membrane/metabolism ; Mice, Transgenic ; RNA, Messenger/metabolism ; Voltage-Dependent Anion Channel 2/metabolism

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Skocz do pozycji: 2.

Tytuł:: The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5.
Autorzy:: Iamshanova O; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.
Hämmerli AF; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.
Ramaye E; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.
Seljmani A; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.; medi-Center for Medical Education, Bern, Switzerland.
Ross-Kaschitza D; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.
Schärz N; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.; medi-Center for Medical Education, Bern, Switzerland.
Essers M; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.
Guichard S; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.
Rougier JS; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.
Abriel H; Faculty of Medicine, Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 07; Vol. 19 (3), pp. e0298820. Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: 14-3-3 Proteins*/genetics
14-3-3 Proteins*/metabolism
Voltage-Gated Sodium Channels*/metabolism
Humans ; Myocytes, Cardiac/metabolism ; Cell Line ; Arrhythmias, Cardiac ; NAV1.5 Voltage-Gated Sodium Channel/genetics ; NAV1.5 Voltage-Gated Sodium Channel/metabolism

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Skocz do pozycji: 3.

Tytuł:: Impact on backpropagation of the spatial heterogeneity of sodium channel kinetics in the axon initial segment.
Autorzy:: Barlow BSM; Department of Physics, University of Ottawa, STEM Complex, 150 Louis-Pasteur Pvt, Ottawa, Ontario, Canada.
Longtin A; Department of Physics, University of Ottawa, STEM Complex, 150 Louis-Pasteur Pvt, Ottawa, Ontario, Canada.; Center for Neural Dynamics and AI, University of Ottawa, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Joós B; Department of Physics, University of Ottawa, STEM Complex, 150 Louis-Pasteur Pvt, Ottawa, Ontario, Canada.; Center for Neural Dynamics and AI, University of Ottawa, Ottawa, Ontario, Canada.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2024 Mar 15; Vol. 20 (3), pp. e1011846. Date of Electronic Publication: 2024 Mar 15 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Axon Initial Segment*/physiology
Voltage-Gated Sodium Channels*
NAV1.6 Voltage-Gated Sodium Channel/ultrastructure ; Axons/physiology ; Neurons/physiology ; Action Potentials/physiology

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Skocz do pozycji: 4.

Tytuł:: Synthesis, Pharmacological Evaluation, and Molecular Modeling of Lappaconitine-1,5-Benzodiazepine Hybrids.
Autorzy:: Cheremnykh KP; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.
Bryzgalov AO; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.
Baev DS; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.
Borisov SA; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.
Sotnikova YS; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.
Savelyev VA; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.
Tolstikova TG; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.
Sagdullaev SS; S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Mirzo Ulugbek Str. 77, Tashkent 100170, Uzbekistan.
Shults EE; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Lavrentjev Avenue 9, 630090 Novosibirsk, Russia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 May 22; Vol. 28 (10). Date of Electronic Publication: 2023 May 22.
Typ publikacji:: Journal Article
MeSH Terms:: Aconitine*/analogs & derivatives
Aconitine*/chemical synthesis
Aconitine*/pharmacology
Benzodiazepines*/chemical synthesis
Benzodiazepines*/chemistry
Benzodiazepines*/pharmacology
Analgesics, Non-Narcotic*/chemical synthesis
Analgesics, Non-Narcotic*/chemistry
Analgesics, Non-Narcotic*/pharmacology
Anti-Arrhythmia Agents*/chemical synthesis
Anti-Arrhythmia Agents*/chemistry
Anti-Arrhythmia Agents*/pharmacology
Voltage-Gated Sodium Channel Blockers*/chemical synthesis
Voltage-Gated Sodium Channel Blockers*/chemistry
Voltage-Gated Sodium Channel Blockers*/pharmacology
Models, Molecular ; Protein Binding ; Animals ; Rats ; Rats, Wistar ; NAV1.5 Voltage-Gated Sodium Channel ; Male ; Mice ; Mice, Inbred Strains ; Molecular Docking Simulation

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Skocz do pozycji: 5.

Tytuł:: Sensitive Detection of Ciguatoxins Using a Neuroblastoma Cell-Based Assay with Voltage-Gated Potassium Channel Inhibitors.
Autorzy:: Yokozeki T; Osaka Saito Laboratory, Japan Food Research Laboratories, 7-4-41 Saitoasagi, Osaka 567-0085, Ibaraki, Japan.; Department of Biological Chemistry, Graduate School of Science, Osaka Metropolitan University, 1-2 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8570, Kanagawa, Japan.
Kawabata M; Department of Biological Chemistry, Graduate School of Science, Osaka Metropolitan University, 1-2 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8570, Kanagawa, Japan.
Fujita K; Osaka Saito Laboratory, Japan Food Research Laboratories, 7-4-41 Saitoasagi, Osaka 567-0085, Ibaraki, Japan.
Hirama M; Department of Biological Chemistry, Graduate School of Science, Osaka Metropolitan University, 1-2 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8570, Kanagawa, Japan.
Tsumuraya T; Department of Biological Chemistry, Graduate School of Science, Osaka Metropolitan University, 1-2 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8570, Kanagawa, Japan.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2024 Feb 29; Vol. 16 (3). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:: Journal Article
MeSH Terms:: Ciguatoxins*
Ciguatera Poisoning*
Potassium Channels, Voltage-Gated*
Neuroblastoma*
Humans ; Animals ; Aminopyridines

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Skocz do pozycji: 6.

Tytuł:: Functional Characteristics of the Nav1.1 p.Arg1596Cys Mutation Associated with Varying Severity of Epilepsy Phenotypes.
Autorzy:: Witkowski G; First Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957 Warsaw, Poland.; Military Institute of Aviation Medicine, Krasinskiego 54/56, 01-755 Warsaw, Poland.
Szulczyk B; Chair and Department of Pharmacotherapy and Pharmaceutical Care, Faculty of Pharmacy, The Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.
Nurowska E; Chair and Department of Pharmacotherapy and Pharmaceutical Care, Faculty of Pharmacy, The Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.
Jurek M; Department of Medical Genetics, Institute of Mother and Child, Kasprzaka 17a, 01-211 Warsaw, Poland.
Pasierski M; Chair and Department of Pharmacotherapy and Pharmaceutical Care, Faculty of Pharmacy, The Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.
Lipiec A; Clinic of Pediatric Neurology, Institute of Mother and Child, Kasprzaka 17a, 01-211 Warsaw, Poland.
Charzewska A; Department of Medical Genetics, Institute of Mother and Child, Kasprzaka 17a, 01-211 Warsaw, Poland.
Dawidziuk M; Department of Medical Genetics, Institute of Mother and Child, Kasprzaka 17a, 01-211 Warsaw, Poland.
Milewski M; Department of Medical Genetics, Institute of Mother and Child, Kasprzaka 17a, 01-211 Warsaw, Poland.
Owsiak S; First Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957 Warsaw, Poland.
Rola R; Military Institute of Aviation Medicine, Krasinskiego 54/56, 01-755 Warsaw, Poland.
Sienkiewicz Jarosz H; First Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957 Warsaw, Poland.
Hoffman-Zacharska D; Department of Medical Genetics, Institute of Mother and Child, Kasprzaka 17a, 01-211 Warsaw, Poland.; Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02-096 Warsaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 01; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:: Journal Article
MeSH Terms:: Epilepsy*/pathology
Epilepsy, Generalized*/genetics
Seizures, Febrile*
NAV1.1 Voltage-Gated Sodium Channel*/genetics
NAV1.1 Voltage-Gated Sodium Channel*/metabolism
Humans ; Mutation ; Phenotype

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Skocz do pozycji: 7.

Tytuł:: µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype Na V 1.7.
Autorzy:: McMahon KL; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Tran HNT; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Deuis JR; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Craik DJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Vetter I; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.; The School of Pharmacy, The University of Queensland, Woolloongabba, QLD 4102, Australia.
Schroeder CI; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2022 Aug 30; Vol. 14 (9). Date of Electronic Publication: 2022 Aug 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural
MeSH Terms:: Conotoxins*/chemistry
Conotoxins*/pharmacology
Voltage-Gated Sodium Channel Blockers*/chemistry
Voltage-Gated Sodium Channel Blockers*/pharmacology
Analgesics/chemistry ; Analgesics/pharmacology ; Animals ; Cysteine ; Humans ; NAV1.4 Voltage-Gated Sodium Channel ; NAV1.7 Voltage-Gated Sodium Channel ; Peptides

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Skocz do pozycji: 8.

Tytuł:: Exploring the Pivotal Components Influencing the Side Effects Induced by an Analgesic-Antitumor Peptide from Scorpion Venom on Human Voltage-Gated Sodium Channels 1.4 and 1.5 through Computational Simulation.
Autorzy:: Zhao F; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China.
Fang L; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China.
Wang Q; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China.
Ye Q; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China.
He Y; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China.
Xu W; Faculty of Functional Food and Wine, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China.
Song Y; School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2022 Dec 31; Vol. 15 (1). Date of Electronic Publication: 2022 Dec 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Scorpion Venoms*/chemistry
Voltage-Gated Sodium Channels*
Spider Venoms*/chemistry
Humans ; Analgesics/adverse effects ; Peptides/pharmacology ; Computer Simulation ; NAV1.7 Voltage-Gated Sodium Channel

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Skocz do pozycji: 9.

Tytuł:: Solute Transport through Mitochondrial Porins In Vitro and In Vivo.
Autorzy:: Benz R; Science Faculty, Constructor University Bremen, Campus-Ring 1, 28759 Bremen, Germany.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2024 Mar 04; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Ion Channels*/metabolism
Voltage-Dependent Anion Channels*/metabolism
Porins/analysis ; Porins/chemistry ; Porins/metabolism ; Mitochondrial Membranes/metabolism ; Mitochondria/metabolism ; Membrane Potentials

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Skocz do pozycji: 10.

Tytuł:: E as in Enigma: The Mysterious Role of the Voltage-Dependent Anion Channel Glutamate E73.
Autorzy:: Rister AB; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, LMU Munich, 80336 Munich, Germany.
Gudermann T; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, LMU Munich, 80336 Munich, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung, Partner Site Munich Heart Alliance, Munich, Germany.
Schredelseker J; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, LMU Munich, 80336 Munich, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung, Partner Site Munich Heart Alliance, Munich, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Dec 23; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 23.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Glutamic Acid*/metabolism
Voltage-Dependent Anion Channel 1*/metabolism
Voltage-Dependent Anion Channels/metabolism ; Mitochondrial Membranes/metabolism ; Mitochondria/metabolism

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Skocz do pozycji: 11.

Tytuł:: Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Narirutin via Block of Na v 1.7 Voltage-Gated Sodium Channel.
Autorzy:: Yang H; Department of Anatomy and Histology, Shenzhen University Health Science Center, Shenzhen 518060, China.
Shan Z; Laboratory and Clinical Research Institute for Pain, Department of Anaesthesiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; Department of Anesthesiology, Shenzhen People's Hospital (The First Affiliated Hospital, Southern University of Science and Technology; The Second Clinical Medical College, Jinan University), Shenzhen 518020, China.; Shenzhen Engineering Research Center of Anesthesiology, Shenzhen 518020, China.
Guo W; Department of Anatomy and Histology, Shenzhen University Health Science Center, Shenzhen 518060, China.
Wang Y; Department of Anatomy and Histology, Shenzhen University Health Science Center, Shenzhen 518060, China.
Cai S; Department of Anatomy and Histology, Shenzhen University Health Science Center, Shenzhen 518060, China.
Li F; Department of Anatomy and Histology, Shenzhen University Health Science Center, Shenzhen 518060, China.
Huang Q; Department of Anatomy and Histology, Shenzhen University Health Science Center, Shenzhen 518060, China.
Liu JA; Department of Neuroscience, City University of Hong Kong, Hong Kong 999077, China.
Cheung CW; Laboratory and Clinical Research Institute for Pain, Department of Anaesthesiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.
Cai S; Department of Anatomy and Histology, Shenzhen University Health Science Center, Shenzhen 518060, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 27; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 27.
Typ publikacji:: Journal Article
MeSH Terms:: Biological Products*/pharmacology
Biological Products*/therapeutic use
Biological Products*/metabolism
Neuralgia*/drug therapy
Neuralgia*/metabolism
Voltage-Gated Sodium Channels*/metabolism
Rats ; Humans ; Animals ; HEK293 Cells ; Rats, Sprague-Dawley ; Ganglia, Spinal/metabolism ; Tetrodotoxin/pharmacology ; Sensory Receptor Cells/metabolism ; Analgesics/pharmacology ; Analgesics/therapeutic use ; Analgesics/metabolism ; NAV1.7 Voltage-Gated Sodium Channel/metabolism

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Skocz do pozycji: 12.

Tytuł:: Pyrethroid resistance status and co-occurrence of V1016G, F1534C and S989P mutations in the Aedes aegypti population from two dengue outbreak counties along the China-Myanmar border.
Autorzy:: Chen L; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.; Yunnan International Joint Laboratory of Tropical Infectious Diseases, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Key Technology Innovation Team for Insect Borne Infectious Disease Prevention and Control, Yunnan Institute of Parasitic Diseases, Pu'er, China.
Zhou K; Yunnan International Joint Laboratory of Tropical Infectious Diseases, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Key Technology Innovation Team for Insect Borne Infectious Disease Prevention and Control, Yunnan Institute of Parasitic Diseases, Pu'er, China.
Shi J; Lincang Center for Disease Control and Prevention, Lincang, China.
Zheng Y; Yunnan International Joint Laboratory of Tropical Infectious Diseases, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Key Technology Innovation Team for Insect Borne Infectious Disease Prevention and Control, Yunnan Institute of Parasitic Diseases, Pu'er, China.
Zhao X; Yunnan International Joint Laboratory of Tropical Infectious Diseases, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Key Technology Innovation Team for Insect Borne Infectious Disease Prevention and Control, Yunnan Institute of Parasitic Diseases, Pu'er, China.
Du Q; Gengma Center for Disease Control and Prevention, Gengma, China.
Lin Y; Dehong Prefecture Center for Disease Control and Prevention, Mangshi, China.
Yin X; Ruili Center for Disease Control and Prevention, Ruili, China.
Jiang J; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China. .; Yunnan International Joint Laboratory of Tropical Infectious Diseases, Yunnan Provincial Key Laboratory of Vector-Borne Diseases Control and Research, Yunnan Key Technology Innovation Team for Insect Borne Infectious Disease Prevention and Control, Yunnan Institute of Parasitic Diseases, Pu'er, China. .
Feng X; School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, 20025, China. .; One Health Center, Shanghai Jiao Tong University, The University of Edinburgh, Shanghai, 20025, China. .; Pokaż więcej
Źródło:: Parasites & vectors [Parasit Vectors] 2024 Feb 27; Vol. 17 (1), pp. 91. Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:: Journal Article
MeSH Terms:: Insecticides*/pharmacology
Aedes*/genetics
Pyrethrins*/pharmacology
Voltage-Gated Sodium Channels*/genetics
Dengue*/epidemiology
Dengue*/prevention & control
Nitriles*
Animals ; Permethrin ; Myanmar ; China/epidemiology ; Mutation ; Insecticide Resistance/genetics ; Disease Outbreaks ; Mosquito Vectors/genetics

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Skocz do pozycji: 13.

Tytuł:: Upregulation of Na v 1.6 Mediated by the p38 MAPK Pathway in the Dorsal Root Ganglia Contributes to Cancer-Induced Bone Pain in Rats.
Autorzy:: Lin M; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350000, China.
Chen X; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350000, China.
Wu S; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350000, China.
Chen P; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350000, China.
Wan H; Department of Anesthesiology, First Affiliated Hospital of Yangtze University, First People's Hospital of Jingzhou, Jingzhou 434000, China.
Ma S; Fujian Provincial Maternity and Children's Hospital, Fuzhou 350000, China.
Lin N; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350000, China.
Liao Y; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350000, China.
Zheng T; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350000, China.
Jiang J; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350000, China.
Zheng X; Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou 350000, China.; Fujian Emergency Medical Center, Fujian Provincial Key Laboratory of Critical Care Medicine, Fuzhou 350000, China.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Oct 26; Vol. 11 (21). Date of Electronic Publication: 2022 Oct 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: p38 Mitogen-Activated Protein Kinases*/metabolism
NAV1.6 Voltage-Gated Sodium Channel*/genetics
NAV1.6 Voltage-Gated Sodium Channel*/metabolism
Cancer Pain*/genetics
Cancer Pain*/metabolism
Animals ; Rats ; Bone Neoplasms/complications ; Bone Neoplasms/metabolism ; Ganglia, Spinal/metabolism ; Pain/genetics ; Pain/metabolism ; Rats, Sprague-Dawley ; Up-Regulation ; Voltage-Gated Sodium Channels/metabolism

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Skocz do pozycji: 14.

Tytuł:: Neonatal Na V 1.5 channels: pharmacological distinctiveness of a cancer-related voltage-gated sodium channel splice variant.
Autorzy:: Fraser SP; Department of Life Sciences, Neuroscience Solutions to Cancer Research Group, Imperial College London, London, UK.
Onkal R; Department of Life Sciences, Neuroscience Solutions to Cancer Research Group, Imperial College London, London, UK.; Biotechnology Research Centre, Cyprus International University, Mersin 10, Turkey.
Theys M; Department of Basic and Applied Medical Sciences, University of Ghent, Ghent, Belgium.
Bosmans F; Department of Basic and Applied Medical Sciences, University of Ghent, Ghent, Belgium.
Djamgoz MBA; Department of Life Sciences, Neuroscience Solutions to Cancer Research Group, Imperial College London, London, UK.; Biotechnology Research Centre, Cyprus International University, Mersin 10, Turkey.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Feb; Vol. 179 (3), pp. 473-486. Date of Electronic Publication: 2021 Dec 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma*
Spider Venoms*/chemistry
Voltage-Gated Sodium Channels*/metabolism
Humans ; NAV1.7 Voltage-Gated Sodium Channel/metabolism ; Voltage-Gated Sodium Channel Blockers/chemistry ; Voltage-Gated Sodium Channel Blockers/pharmacology

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Skocz do pozycji: 15.

Tytuł:: Voltage-Gated Sodium Channel Inhibition by µ-Conotoxins.
Autorzy:: McMahon KL; Institute for Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Vetter I; Institute for Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.; The School of Pharmacy, The University of Queensland, Woolloongabba, QLD 4102, Australia.
Schroeder CI; Institute for Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.; Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2024 Jan 18; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Conotoxins*/pharmacology
Voltage-Gated Sodium Channels*
Disulfides ; Structure-Activity Relationship

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Skocz do pozycji: 16.

Tytuł:: First report of kdr mutations in the voltage-gated sodium channel gene in the arbovirus vector, Aedes aegypti, from Nouakchott, Mauritania.
Autorzy:: Ould Lemrabott MA; Université de Nouakchott, UR-GEMI, Nouveau Campus Universitaire, BP 5026, Nouakchott, Mauritania.
Briolant S; Aix Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France. .; IHU-Méditerranée Infection, Marseille, France. .; Unité de Parasitologie Entomologie, Département de Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées (IRBA), Marseille, France. .
Gomez N; Aix Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France.; IHU-Méditerranée Infection, Marseille, France.; Unité de Parasitologie Entomologie, Département de Microbiologie et Maladies Infectieuses, Institut de Recherche Biomédicale des Armées (IRBA), Marseille, France.
Basco L; Aix Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France.; IHU-Méditerranée Infection, Marseille, France.
Ould Mohamed Salem Boukhary A; Université de Nouakchott, UR-GEMI, Nouveau Campus Universitaire, BP 5026, Nouakchott, Mauritania. .; Aix Marseille Université, IRD, AP-HM, SSA, VITROME, Marseille, France. .; Pokaż więcej
Źródło:: Parasites & vectors [Parasit Vectors] 2023 Dec 19; Vol. 16 (1), pp. 464. Date of Electronic Publication: 2023 Dec 19.
Typ publikacji:: Journal Article
MeSH Terms:: Insecticides*/pharmacology
Aedes*/genetics
Arboviruses*
Pyrethrins*
Voltage-Gated Sodium Channels*/genetics
Dengue*/prevention & control
Animals ; Female ; Humans ; Mauritania ; Mutation ; Insecticide Resistance/genetics ; Mosquito Vectors/genetics

Czasopismo naukowe

na półce

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Skocz do pozycji: 17.

Tytuł:: Combining nano-differential scanning fluorimetry and microscale thermophoresis to investigate VDAC1 interaction with small molecules.
Autorzy:: Gorny H; Centre de Recherche en Cancérologie de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Lyon, France.
Mularoni A; Centre de Recherche en Cancérologie de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Lyon, France.
Delcros JG; Centre de Recherche en Cancérologie de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Lyon, France.
Freton C; Molecular Microbiology and Structural Biochemistry, UMR 5086, Université de Lyon, CNRS, Lyon, France.
Preto J; Centre de Recherche en Cancérologie de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Lyon, France.
Krimm I; Centre de Recherche en Cancérologie de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Lyon, France.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2121821.
Typ publikacji:: Journal Article
MeSH Terms:: Voltage-Dependent Anion Channel 1*/chemistry
Voltage-Dependent Anion Channel 1*/metabolism
Cannabidiol*/metabolism
Mitochondria/metabolism ; Apoptosis

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Skocz do pozycji: 18.

Tytuł:: Sodium Channel β Subunits-An Additional Element in Animal Tetrodotoxin Resistance?
Autorzy:: Seneci L; Adaptive Biotoxicology Lab, School of the Environment, The University of Queensland, St Lucia, QLD 4067, Australia.
Mikheyev AS; Evolutionary Genomics Group, Research School of Biology, Australian National University, Canberra, ACT 0200, Australia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 25; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:: Journal Article
MeSH Terms:: Voltage-Gated Sodium Channels*/genetics
Animals ; Tetrodotoxin/pharmacology ; Likelihood Functions ; Sodium Channel Blockers/pharmacology

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Skocz do pozycji: 19.

Tytuł:: Kdr genotyping and the first report of V410L and V1016I kdr mutations in voltage-gated sodium channel gene in Aedes aegypti (Diptera: Culicidae) from Iran.
Autorzy:: Enayati A; Department of Medical Entomology and Vector Control, School of Public Health and Health Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran. .
Valadan R; Department of Immunology and Molecular and Cellular Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Bagherzadeh M; Department of Medical Entomology and Vector Control, School of Public Health, Student Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Cheraghpour M; Department of Medical Entomology and Vector Control, School of Public Health, Student Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Nikookar SH; Health Sciences Research Center, Department of Medical Entomology and Vector Control, School of Public Health, Mazandaran University of Medical Sciences, Sari, Iran.
Fazeli-Dinan M; Health Sciences Research Center, Department of Medical Entomology and Vector Control, School of Public Health, Mazandaran University of Medical Sciences, Sari, Iran.
Hosseini-Vasoukolaei N; Department of Medical Entomology and Vector Control, School of Public Health, Mazandaran University of Medical Sciences, Sari, Iran.
Sahraei Rostami F; Department of Medical Entomology and Vector Control, School of Public Health, Mazandaran University of Medical Sciences, Sari, Iran.
Shabani Kordshouli R; Department of Medical Entomology and Vector Control, School of Public Health, Mazandaran University of Medical Sciences, Sari, Iran.
Raeisi A; Vector Borne Diseases Control Department, Iran CDC, Ministry of Health and Medical Education, Tehran, Iran.; Department of Medical Parasitology & Mycology, Tehran University of Medical Sciences, Tehran, Iran.
Nikpour F; Vector Borne Diseases Control Department, Iran CDC, Ministry of Health and Medical Education, Tehran, Iran.; Department of Environmental Chemical Pollutants and Pesticides, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran.
Mirolyaei A; Vector Borne Diseases Control Department, Iran CDC, Ministry of Health and Medical Education, Tehran, Iran.
Bagheri F; Hormozgan Provincial Health Center, Department of Communicable Diseases Control, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Sedaghat MM; Department of Medical Entomology and Vector Control, Tehran University of Medical Sciences, Tehran, Iran.
Zaim M; Department of Medical Entomology and Vector Control, Tehran University of Medical Sciences, Tehran, Iran.
Weetman D; Vector Biology Department, Liverpool School of Tropical Medicine, Liverpool, UK.
Hemigway J; Vector Biology Department, Liverpool School of Tropical Medicine, Liverpool, UK.; Pokaż więcej
Źródło:: Parasites & vectors [Parasit Vectors] 2024 Jan 25; Vol. 17 (1), pp. 34. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:: Journal Article
MeSH Terms:: Aedes*/genetics
Insecticides*/pharmacology
Pyrethrins*/pharmacology
Voltage-Gated Sodium Channels*/genetics
Animals ; Iran ; Genotype ; Phylogeny ; Mutation ; Insecticide Resistance/genetics ; Mosquito Vectors/genetics

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Skocz do pozycji: 20.

Tytuł:: Snake Venom: A Promising Source of Neurotoxins Targeting Voltage-Gated Potassium Channels.
Autorzy:: AlShammari AK; College of Engineering and Technology, American University of the Middle East, Egaila 54200, Kuwait.
Abd El-Aziz TM; Zoology Department, Faculty of Science, Minia University, El-Minia 61519, Egypt.; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Al-Sabi A; College of Engineering and Technology, American University of the Middle East, Egaila 54200, Kuwait.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2023 Dec 25; Vol. 16 (1). Date of Electronic Publication: 2023 Dec 25.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Potassium Channels, Voltage-Gated*
Neurotoxicity Syndromes*
Humans ; Neurotoxins/toxicity ; Snake Venoms ; Cardiotoxicity

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