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Tytuł :
[Tripeptidyl peptidase 1 deficiency in neuronal ceroid lipofuscinosis. A novel mutation].
Autorzy :
Bukina AM; Research Centre for Medical Genetics RAMS, 117478, Moscow Moscvorechij St. 1. />Tsvetkova IV
Semiachkina AN
Il'ina ES
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Transliterated Title :
Nedostatochnost' tripeptidil peptidazy 1 pri neĭronal'nom tseroidnom lipofuktsinoze. Novaia mutatsiia.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 594-8.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Endopeptidases/*genetics
Neuronal Ceroid-Lipofuscinoses/*genetics
Amino Acid Sequence ; Aminopeptidases ; Child ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases ; Endopeptidases/deficiency ; Humans ; Mutation ; Neuronal Ceroid-Lipofuscinoses/diagnosis ; Serine Proteases
Czasopismo naukowe
Tytuł :
[Inhibition by IFN-(Asp)4-Lys-HIV chimeric protein of hydrolysis of the low molecular substrate by the enteropeptidase light chain].
Autorzy :
Shibanova ED; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP-7, Moscow, 117997 Russia. />Grishina IuB
Rumsh LD
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Transliterated Title :
Ingibirovanie khimernym belkom IFN-(Asp)4-Lys-HIV gidroliza nizkomolekuliarnogo substrata legkoĭ tsep'iu énteropeptidazy.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 599-602.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Aspartic Acid/*genetics
Enteropeptidase/*chemistry
HIV Protease/*genetics
Interferon-gamma/*genetics
Mucoproteins/*genetics
Oligopeptides/*chemistry
Recombinant Fusion Proteins/*chemistry
Catalysis ; Depression, Chemical ; Hydrolysis ; Kinetics ; Molecular Weight ; Recombinant Fusion Proteins/genetics
Czasopismo naukowe
Tytuł :
[Comparative analysis of differentiating and apoptogenic effects of cytidine, thymidine, and guanosine on cells of human erythromyeloleukemic cell line K562].
Autorzy :
Volkova TO; Petrozavodsk State University, prosp. Lenina, 33, Petrozavodsk, 185640, Russia. />Malysheva IE
Nemova NN
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Transliterated Title :
Sravnitel'nyĭ analiz differentsiruiushchego i apoptogennogo deĭstviĭ tsitidina, timidina i guanozina na kletki éritromieloleĭkoznoĭ linii cheloveka K562.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 586-93.
Typ publikacji :
Comparative Study; English Abstract; Journal Article
MeSH Terms :
Apoptosis*
Antineoplastic Agents/*pharmacology
Cytidine/*pharmacology
Guanosine/*pharmacology
Thymidine/*pharmacology
Caspases/metabolism ; Cell Differentiation/drug effects ; Cell Division/drug effects ; Hemoglobins/biosynthesis ; Humans ; Leukemia, Erythroblastic, Acute ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
[Study of functional activity of components and factors of the human complement system].
Autorzy :
Kozlov LV; G.N. Gabrichevsky Moscow Scientific Research Institute of Epidemiology and Microbiology, 125212 Moscow, Street of Admiral Makarova.
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Transliterated Title :
Issledovanie funktsional'noĭ aktivnosti komponentov i faktorov sistemy komplementa cheloveka.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 624-31.
Typ publikacji :
English Abstract; Journal Article; Review
MeSH Terms :
Complement System Proteins/*analysis
Autoantibodies/blood ; Clinical Laboratory Techniques ; Complement Activation ; Complement System Proteins/immunology ; Hematologic Tests/methods ; Hemolysis ; Humans ; Immunoenzyme Techniques/methods ; Immunoglobulin A/blood ; Immunoglobulin G/blood ; Immunoglobulin M/blood ; Reagent Kits, Diagnostic
Czasopismo naukowe
Tytuł :
[Selected proceedings of the V Symposium on Structure and Functions of Proteolytic Enzymes dedicated to the 75th birthday of Vladimir Konstantinovich Antonov. Moscow, April 22-24, 2002].
Transliterated Title :
Izbrannye doklady V simpoziuma "Struktura i funktsii proteoliticheskikh fermentov", posviashchennyĭ 75-letiiu so dnia rozhdeniia Vladimira Konstantinovicha Antonova. Moskva, 22-24 aprelia 2002 g.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 541-631.
Typ publikacji :
Biography; Congress; Festschrift; Historical Article
MeSH Terms :
Endopeptidases*
Biochemistry/history ; History, 20th Century ; History, 21st Century ; Russia ; USSR
Personal Name as Subject :
Antonov VK
Biography
Tytuł :
[Ulysses retrotransposon aspartate proteinase (Drosophila virilis)].
Autorzy :
Volkov DA; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Miklukho-Maklaya st. 16/10, 117871 Russia. />Savvateeva LV
Dergousova NI
Rumsh LD
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Transliterated Title :
Aspartatnaia proteinaza retrotranspozona Ulysses (Drosophila virilis).
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 553-60.
Typ publikacji :
Journal Article
MeSH Terms :
Retroelements*
Aspartic Acid Endopeptidases/*genetics
Drosophila/*genetics
Drosophila Proteins/*genetics
Amino Acid Sequence ; Animals ; Aspartic Acid Endopeptidases/isolation & purification ; Conserved Sequence ; Drosophila Proteins/isolation & purification ; Escherichia coli/metabolism ; Humans ; Molecular Sequence Data ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification
Czasopismo naukowe
Tytuł :
[Peptide hydrolases with catalytic dyad Ser-Lys. Similarity and distinctions of the active centers of ATP-dependent Lon proteases, LexA repressors, signal peptidases and C-terminal processing proteases].
Autorzy :
Rotanova TV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Siences, Ul. Miklukho-Maklaya 16/10, GSP Moscow, 117997 Russia.
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Transliterated Title :
Peptidgidrolazy s kataliticheskoĭ diadoĭ Ser-Lys. Skhodstvo i razlichiia aktivnykh tsentrov ATP-zavisimykh Lon-proteinaz, repressorov LexA, signal'nykh peptidaz i proteinaz C-kontsevogo protsessinga.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 541-52.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Membrane Proteins*
Bacterial Proteins/*chemistry
Endopeptidases/*chemistry
Heat-Shock Proteins/*chemistry
Lysine/*chemistry
Serine/*chemistry
Serine Endopeptidases/*chemistry
ATP-Dependent Proteases ; Amino Acid Sequence ; Bacterial Proteins/genetics ; Catalytic Domain ; Endopeptidases/genetics ; Heat-Shock Proteins/genetics ; Molecular Sequence Data ; Serine Endopeptidases/genetics
Czasopismo naukowe
Tytuł :
[Polymer coatings with immobilized thrombin and peptides: preparation and use for wound healing].
Autorzy :
Markvicheva EA; Shemyakin Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Str. 16/10, Moscow, 117997 Russia. />Kuptsova SV
Rumsh LD
Dugina TN
Lange MA
Chistov IV
Strukova SM
Zubov VP
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Transliterated Title :
Polimernye pokrytiia s immobilizovannymi v nikh trombinom ili peptidami: poluchenie i primenenie dlia ranozazhivleniia.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 570-6.
Typ publikacji :
Journal Article
MeSH Terms :
Caprolactam/*analogs & derivatives
Peptide Fragments/*chemistry
Thrombin/*chemistry
Wound Healing/*drug effects
Alginates/chemistry ; Animals ; Caprolactam/chemistry ; Drug Carriers ; Enzymes, Immobilized ; Glucuronic Acid ; Hexuronic Acids ; Hydrogels ; Mice ; Mice, Inbred CBA ; Peptide Fragments/therapeutic use ; Polymers/chemistry ; Receptor, PAR-1 ; Receptor, PAR-2 ; Receptors, Thrombin/agonists ; Thrombin/therapeutic use
Czasopismo naukowe
Tytuł :
[Isolation, purification, and properties of factor XII and its active fragment (beta-XIIa)].
Autorzy :
Blokhina TB; Russian Medical Academy of Postgraduate Education, Barrikadnaya st., 2, Moscow, 123995 Russia.
Neshkova EA
Iarovaia GA
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Transliterated Title :
Poluchenie, ochistka, svoĭstva faktora XII i ego aktivnogo fragmenta (beta-XIIa).
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 603-10.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Factor XII/*chemistry
Factor XII/*isolation & purification
Chromatography, Gel ; Chromatography, Ion Exchange ; Electrophoresis, Polyacrylamide Gel ; Humans
Czasopismo naukowe
Tytuł :
[Characterization of cysteine proteinase endogenous inhibitors obtained from transformed fibroblasts].
Autorzy :
Dilakian EA; Institute of Biomedical Chemistry Russian Academy of Medical Sciences (RAMS), Pogodinskaya St. 10, Moscow, 119121 Russia.
Gureeva TA
Zhurbitskaia VA
Suletskaia IuA
Solov'eva NI
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Transliterated Title :
Kharakteristika éndogennykh ingibitorov tsiteinovykh proteinaz iz transformirovannykh fibroblastov.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 611-7.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Cysteine Proteinase Inhibitors/*chemistry
Fibroblasts/*chemistry
Animals ; Cathepsin B/antagonists & inhibitors ; Cathepsin B/chemistry ; Cathepsin L ; Cathepsins/antagonists & inhibitors ; Cathepsins/chemistry ; Cell Line, Transformed ; Cells, Cultured ; Chromatography, Gel ; Cysteine Endopeptidases ; Cysteine Proteinase Inhibitors/isolation & purification ; Kinetics ; Papain/antagonists & inhibitors ; Papain/chemistry ; Rats ; Rats, Inbred F344
Czasopismo naukowe
Tytuł :
[Hydrolysis by enteropeptidase of nonspecific (model) peptide sequences and possible physiological role of this phenomenon].
Autorzy :
Likhareva VV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP-7, Moscow, 117997 Russia.
Mikhaĭlova AG
Rumsh LD
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Transliterated Title :
Gidroliz énteropeptidazoĭ nespetsificheskikh (model'nykh) peptidnykh posledovatel'nosteĭ i vozmozhnaia fiziologicheskaia rol' étogo iavleniia.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 561-9.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Enteropeptidase/*chemistry
Peptides/*chemistry
Amino Acid Sequence ; Animals ; Calcium/metabolism ; Catalytic Domain ; Cattle ; Enteropeptidase/metabolism ; Hydrolysis ; Molecular Sequence Data ; Oligopeptides/chemistry ; Peptides/metabolism ; Trypsin/metabolism
Czasopismo naukowe
Tytuł :
[Stability of immobilized insulin preparation at various pH].
Autorzy :
Valuev IL; Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Leninsky prospect, 29, Moscow, 117912 Russia. />Sytov GA
Valuev LI
Vanchugova LV
Pan AV
Ul'ianova MV
Platé NA
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Transliterated Title :
Stabil'nost' preparata immobilizovannogo insulina pri razlichnykh pH.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 618-23.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Insulin/*chemistry
Acrylic Resins/chemistry ; Animals ; Drug Carriers ; Drug Stability ; Ducks ; Hydrogels ; Hydrogen-Ion Concentration ; Kinetics ; Osmolar Concentration ; Ovomucin/chemistry
Czasopismo naukowe
Tytuł :
[Characterization of S1' subsite specificity of Thermoactinomyces vulgaris carboxypeptidase T by site-directed mutagenesis].
Autorzy :
Trachuk LA; Institute of Genetics and Selection of Industrial Microarganisms, Maskow, Russia.
Bushueva AM
Shevelev AB
Novgorodova SA
Akparov VKh
Chestukhina GG
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Transliterated Title :
Izuchenie S1'-karmana pervichnoĭ spetsifichnosti karboksipeptidazy T Thermoactinomyces vulgaris metodom napravlennogo mutageneza.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Nov-Dec; Vol. 48 (6), pp. 577-85.
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Proteins*
Carboxypeptidases/*chemistry
Micromonosporaceae/*enzymology
Amino Acid Sequence ; Amino Acid Substitution ; Carboxypeptidases/genetics ; Carboxypeptidases/metabolism ; Escherichia coli/metabolism ; Hydrolysis ; Kinetics ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Substrate Specificity
Czasopismo naukowe
Tytuł :
[Computer model of 3D structure of cytochrome P450 2B4].
Autorzy :
Sechenykh AA; Orekhovich Institute of Biomedical Chemistry RAMS, 10, Pogodinskaya str., Moscow, 119121, Russia.
Dubanov AV
Skvortsov VS
Ivanov AS
Archakov AI
Williams P
Cosme J
Johnson EF
McRee DE
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Transliterated Title :
Komp'iuternaia model' trekhmernoĭ struktury tsitokhroma P450 2B4.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Sep-Oct; Vol. 48 (5), pp. 526-38.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Computer Simulation*
Aryl Hydrocarbon Hydroxylases/*chemistry
Amino Acid Sequence ; Cytochrome P-450 Enzyme System/chemistry ; Cytochrome P450 Family 2 ; Models, Molecular ; Molecular Sequence Data ; Protein Structure, Secondary ; Sequence Alignment ; Steroid 21-Hydroxylase/chemistry
Czasopismo naukowe
Tytuł :
[Glutamine metabolism in the liver after partial hepatectomy in chronic hepatitis].
Autorzy :
Savilov PN; Burdenko Voronezh State Medical Academy, 394622 Voronezh, Stydencheskaya st., 10.
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Transliterated Title :
Metabolizm glutamina v pecheni posle chastichnoĭ gepatéktomii na fone khronicheskogo gepatita.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Sep-Oct; Vol. 48 (5), pp. 461-8.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Hepatectomy*
Glutamine/*metabolism
Hepatitis, Chronic/*metabolism
Liver/*metabolism
Animals ; Carbon Tetrachloride Poisoning/metabolism ; Carbon Tetrachloride Poisoning/surgery ; Female ; Glutamate-Ammonia Ligase/antagonists & inhibitors ; Glutaminase/metabolism ; Hepatitis, Chronic/surgery ; Liver/enzymology ; Postoperative Period ; Rats
Czasopismo naukowe
Tytuł :
[Effect of nifedipine and verapamil on cytosolic glucocorticoid receptors in hemorrhagic shock].
Autorzy :
Golikov PP; Sklifosovsky Institute for Emergency Medicine, Russia Moscow, B. Sukharevskaya pl., 3, 129010.
Kozhevnikova LM
Nikolaeva NIu
Arkhipenko IuV
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Transliterated Title :
Vliianie nifedipina i verapamila na svoĭstva tsitozol'nykh gliukokortikoidnykh retseptorov pri gemorragicheskom shoke.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Sep-Oct; Vol. 48 (5), pp. 503-12.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Calcium Channel Blockers/*pharmacology
Cytosol/*metabolism
Nifedipine/*pharmacology
Receptors, Glucocorticoid/*metabolism
Shock, Hemorrhagic/*metabolism
Verapamil/*pharmacology
Animals ; Blood Pressure/drug effects ; Cytosol/drug effects ; Liver/cytology ; Liver/drug effects ; Liver/metabolism ; Male ; Rats ; Rats, Wistar ; Receptors, Glucocorticoid/antagonists & inhibitors ; Shock, Hemorrhagic/physiopathology
Czasopismo naukowe
Tytuł :
[Effect of treatment with perftoran on the course of experimental uveitis, lipid peroxidation and activity of antioxidant defense enzymes].
Autorzy :
Karimova MKh; 2nd Tashkent State Medical Institute, Uzbekistan.
Inoiatova FKh
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Transliterated Title :
Techenie éksperimental'nogo uveita, protsessy perekisnogo okisleniia lipidov i aktivnost' fermentov antioksidantnoĭ zashchity na fone lecheniia perftoranom.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Sep-Oct; Vol. 48 (5), pp. 450-4.
Typ publikacji :
Comparative Study; English Abstract; Journal Article
MeSH Terms :
Antioxidants/*therapeutic use
Catalase/*metabolism
Fluorocarbons/*therapeutic use
Lipid Peroxidation/*drug effects
Staphylococcal Infections/*drug therapy
Superoxide Dismutase/*metabolism
Uveitis, Suppurative/*drug therapy
Animals ; Anti-Bacterial Agents/therapeutic use ; Catalase/blood ; Gentamicins/therapeutic use ; Male ; Rabbits ; Staphylococcal Infections/metabolism ; Superoxide Dismutase/blood ; Uveitis, Suppurative/metabolism ; Uveitis, Suppurative/microbiology
Czasopismo naukowe
Tytuł :
[Effect of GABA and pyracetam on mitochondrial ADP phosphorylation in experimental hypokinesia].
Autorzy :
Sotskiĭ OP; Department of Pharmacology, Yerevan State Medical University Koryun, st. 2.
Akopian VP
Zhamgarian LG
Zhamgarian AG
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Transliterated Title :
Vliianie GAMK i piratsetama na sistemu fosforilirovaniia ADP mitokhondriĭ v usloviiakh éksperimental'noĭ gipokinezii.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Sep-Oct; Vol. 48 (5), pp. 485-9.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Adenosine Diphosphate/*metabolism
Hypokinesia/*metabolism
Mitochondria, Liver/*metabolism
Nootropic Agents/*pharmacology
Piracetam/*pharmacology
gamma-Aminobutyric Acid/*pharmacology
Animals ; Male ; Mitochondria, Liver/drug effects ; Mitochondria, Liver/enzymology ; Phosphorylation ; Rats ; Succinate Dehydrogenase/metabolism
Czasopismo naukowe
Tytuł :
[Hepatoprotective effects of gamma-L-glutamylhistamine].
Autorzy :
Zheltukhina GA; M. V. Lomonosov Moscow State Academy of Fine Chemical Technology, 117571, Moscow, Vernadskogo pr. 86.
Nebol'sin VE
Krzhechkovskaia VV
Evstigneeva RP
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Transliterated Title :
Gepatoprotektornaia aktivnost' gamma-L-glutamilgistamina.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Sep-Oct; Vol. 48 (5), pp. 443-9.
Typ publikacji :
Journal Article
MeSH Terms :
Carbon Tetrachloride Poisoning/*drug therapy
Chemical and Drug Induced Liver Injury/*drug therapy
Histamine/*analogs & derivatives
Histamine/*therapeutic use
Liver/*drug effects
Protective Agents/*therapeutic use
Animals ; Carbon Tetrachloride Poisoning/metabolism ; Chemical and Drug Induced Liver Injury/metabolism ; Disease Models, Animal ; Female ; Lipid Peroxidation/drug effects ; Liver/metabolism ; Liver Function Tests ; Rats ; Silymarin/therapeutic use
Czasopismo naukowe
Tytuł :
[The activity of NAD(P)-dependent dehydrogenases in blood lymphocytes in children and adolescents with different duration of insulin-dependent diabetes mellitus].
Autorzy :
Savchenko AA; Institute for Medical Problems of the North, Siberian Division of Russian Academy of Medical Sciences, Zheleznjak str., 3-G, Krasnoyarsk, 660022, Russia.
Kriukova EV
Manchuk VT
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Transliterated Title :
Aktivnost' NAD(P)-zavisimykh degidrogenaz v limfotsitakh krovi u deteĭ i podrostkov s raznoĭ prodolzhitel'nost'iu insulinozavisimogo diabeta.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Sep-Oct; Vol. 48 (5), pp. 519-25.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Diabetes Mellitus, Type 1/*blood
Lymphocytes/*enzymology
NADPH Dehydrogenase/*blood
Adolescent ; Child ; Glucosephosphate Dehydrogenase/blood ; Glutamate Dehydrogenase/blood ; Glutathione Reductase/blood ; Humans ; Isocitrate Dehydrogenase/blood ; Time Factors
Czasopismo naukowe

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