Autor: "Voronkov DN" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Deferred Administration of Afobazole Induces Sigma1R-Dependent Restoration of Striatal Dopamine Content in a Mouse Model of Parkinson's Disease.
Autorzy:: Kadnikov IA; Department of Pharmacogenetics, FSBI 'Zakusov Institute of Pharmacology', Baltiyskaya street 8, 125315 Moscow, Russia.
Verbovaya ER; Department of Pharmacogenetics, FSBI 'Zakusov Institute of Pharmacology', Baltiyskaya street 8, 125315 Moscow, Russia.
Voronkov DN; Laboratory of neuromorphology, Research Center of Neurology, Volokolamskoe Highway 80, 125367 Moscow, Russia.
Voronin MV; Department of Pharmacogenetics, FSBI 'Zakusov Institute of Pharmacology', Baltiyskaya street 8, 125315 Moscow, Russia.
Seredenin SB; Department of Pharmacogenetics, FSBI 'Zakusov Institute of Pharmacology', Baltiyskaya street 8, 125315 Moscow, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 15; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 15.
Typ publikacji:: Journal Article
MeSH Terms:: Benzimidazoles/*therapeutic use
Corpus Striatum/*metabolism
Dopamine/*metabolism
Morpholines/*therapeutic use
Parkinson Disease/*drug therapy
Receptors, sigma/*metabolism
Animals ; Benzimidazoles/administration & dosage ; Benzimidazoles/pharmacology ; Corpus Striatum/drug effects ; Ethylenediamines/pharmacology ; Male ; Mice ; Mice, Inbred ICR ; Morpholines/administration & dosage ; Morpholines/pharmacology ; Movement ; Receptors, sigma/agonists ; Receptors, sigma/antagonists & inhibitors ; Sigma-1 Receptor

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Tytuł:: Chaperone Sigma1R mediates the neuroprotective action of afobazole in the 6-OHDA model of Parkinson's disease.
Autorzy:: Voronin MV; Federal State Budgetary Institution 'Research Zakusov Institute of Pharmacology', Department of Pharmacogenetics, Baltiyskaya street 8, Moscow, 125315, Russian Federation.
Kadnikov IA; Federal State Budgetary Institution 'Research Zakusov Institute of Pharmacology', Department of Pharmacogenetics, Baltiyskaya street 8, Moscow, 125315, Russian Federation. .
Voronkov DN; Research Center of Neurology, Laboratory of Functional Morphochemistry, Volokolamskoe Highway 80, Moscow, 125367, Russian Federation.
Seredenin SB; Federal State Budgetary Institution 'Research Zakusov Institute of Pharmacology', Department of Pharmacogenetics, Baltiyskaya street 8, Moscow, 125315, Russian Federation.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Nov 19; Vol. 9 (1), pp. 17020. Date of Electronic Publication: 2019 Nov 19.
Typ publikacji:: Journal Article
MeSH Terms:: Benzimidazoles/*pharmacology
Morpholines/*pharmacology
Neuroprotection/*drug effects
Neuroprotective Agents/*pharmacology
Parkinson Disease/*drug therapy
Receptors, sigma/*metabolism
Animals ; Corpus Striatum/drug effects ; Disease Models, Animal ; Dopamine/metabolism ; Ethylenediamines/pharmacology ; Male ; Mice ; Mice, Inbred ICR ; Neurons/drug effects ; Oxidopamine ; Parkinson Disease/physiopathology ; Receptors, sigma/agonists ; Receptors, sigma/antagonists & inhibitors ; Rotarod Performance Test ; Substantia Nigra/cytology ; Substantia Nigra/drug effects ; Sigma-1 Receptor

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