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Wyświetlanie 1-20 z 35
Tytuł:
Biodegradable polymeric nanoparticles increase risk of cardiovascular diseases by inducing endothelium dysfunction and inflammation.
Autorzy:
Shi W; Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Fuad ARM; Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Li Y; Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Wang Y; Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Huang J; Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Du R; Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Wang G; Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Wang Y; School of Medicine, Chongqing University, Chongqing, 400030, China. yazhou_.
Yin T; Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China. tieying_.
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2023 Feb 24; Vol. 21 (1), pp. 65. Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiovascular Diseases*
Nanoparticles*
Animals ; Mice ; Polylactic Acid-Polyglycolic Acid Copolymer ; Polyglycolic Acid ; Lactic Acid ; Constriction, Pathologic ; Inflammation ; Endothelium ; Drug Carriers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
pH-activated, mitochondria-targeted, and redox-responsive delivery of paclitaxel nanomicelles to overcome drug resistance and suppress metastasis in lung cancer.
Autorzy:
Wang H; Center of Cancer Research, The Second Affiliated Hospital, Guangzhou Medical University, Guangdong, 510260, Guangzhou, People's Republic of China.
Shi W; The Fifth Affiliated Hospital, Key Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangdong, 511436, Guangzhou, People's Republic of China.
Zeng D; The Fifth Affiliated Hospital, Key Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangdong, 511436, Guangzhou, People's Republic of China.; Center of Cancer Research, The Second Affiliated Hospital, Guangzhou Medical University, Guangdong, 510260, Guangzhou, People's Republic of China.
Huang Q; The Fifth Affiliated Hospital, Key Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangdong, 511436, Guangzhou, People's Republic of China.
Xie J; The Fifth Affiliated Hospital, Key Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangdong, 511436, Guangzhou, People's Republic of China.
Wen H; The Fifth Affiliated Hospital, Key Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangdong, 511436, Guangzhou, People's Republic of China.
Li J; Department of Pharmaceutical Sciences, Xinjiang Second Medical College, Kelamayi, 830011, Xinjiang, People's Republic of China.
Yu X; The Fifth Affiliated Hospital, Key Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangdong, 511436, Guangzhou, People's Republic of China.
Qin L; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, Guangdong, People's Republic of China. qins_.
Zhou Y; The Fifth Affiliated Hospital, Key Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangdong, 511436, Guangzhou, People's Republic of China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2021 May 22; Vol. 19 (1), pp. 152. Date of Electronic Publication: 2021 May 22.
Typ publikacji:
Journal Article
MeSH Terms:
Micelles*
Antineoplastic Agents/*pharmacology
Lung Neoplasms/*drug therapy
Mitochondria/*metabolism
Nanoparticles/*chemistry
Paclitaxel/*metabolism
A549 Cells ; Apoptosis ; Drug Delivery Systems/methods ; Drug Resistance, Neoplasm/drug effects ; Humans ; Hydrogen-Ion Concentration ; Mitochondria/drug effects ; Mitochondrial Membranes/drug effects ; Nanoparticles/therapeutic use ; Oxidation-Reduction ; Paclitaxel/chemistry ; Poloxalene
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dimeric Her2-specific affibody mediated cisplatin-loaded nanoparticles for tumor enhanced chemo-radiotherapy.
Autorzy:
Wang H; Department of Pharmacy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, China.; School of Life Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Taian, 271016, China.
Jia D; Laboratory of Drug Discovery and Design, School of Pharmacy, Liaocheng University, Liaocheng, 252000, China.
Yuan D; Department of Digestive Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, China.
Yin X; School of Life Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Taian, 271016, China.
Yuan F; Joint Laboratory for Translational Medicine Research, Liaocheng People's Hospital, Liaocheng, 252000, China.
Wang F; Laboratory of Drug Discovery and Design, School of Pharmacy, Liaocheng University, Liaocheng, 252000, China.
Shi W; Department of Pharmacy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, China.
Li H; Department of Pharmacy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, China.
Zhu LM; College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, 201620, China. .
Fan Q; Department of Pharmacy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2021 May 13; Vol. 19 (1), pp. 138. Date of Electronic Publication: 2021 May 13.
Typ publikacji:
Journal Article
MeSH Terms:
Chemoradiotherapy/*methods
Cisplatin/*chemistry
Cisplatin/*pharmacology
Nanoparticles/*chemistry
Polymers/*chemistry
Receptor, ErbB-2/*chemistry
Animals ; Cell Line, Tumor ; Drug Delivery Systems ; Drug Liberation ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Female ; Humans ; Manganese Compounds ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Nanoparticles/therapeutic use ; Oxides ; Radiation-Sensitizing Agents ; Reactive Oxygen Species/metabolism ; Receptor, ErbB-2/genetics ; Tumor Hypoxia ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
EGFP-EGF1-conjugated poly (lactic-co-glycolic acid) nanoparticles as a carrier for the delivery of CCR2- shRNA to atherosclerotic macrophage in vitro.
Autorzy:
Wu Z; Anesthesiology Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
Chen C; Anesthesiology Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China. .
Luo J; Anesthesiology Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
Davis JRJ; Anesthesiology Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
Zhang B; Haematology Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
Tang L; Haematology Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
Shi W; Haematology Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
Liao D; Haematology Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 12; Vol. 10 (1), pp. 19636. Date of Electronic Publication: 2020 Nov 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Delivery Systems*
Atherosclerosis/*drug therapy
Macrophages/*drug effects
Nanoparticles/*administration & dosage
Polylactic Acid-Polyglycolic Acid Copolymer/*chemistry
RNA, Small Interfering/*pharmacology
Receptors, CCR2/*antagonists & inhibitors
Animals ; Atherosclerosis/metabolism ; Biocompatible Materials/chemistry ; Cell Line ; Drug Carriers/administration & dosage ; Green Fluorescent Proteins/chemistry ; Macrophages/metabolism ; Mice ; Nanoparticles/chemistry ; Peptide Elongation Factor G/chemistry ; RNA, Small Interfering/administration & dosage ; RNA, Small Interfering/chemistry ; Receptors, CCR2/genetics ; Recombinant Fusion Proteins/chemistry ; Transfection
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tumor- and mitochondria-targeted nanoparticles eradicate drug resistant lung cancer through mitochondrial pathway of apoptosis.
Autorzy:
Wang H; Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.; Center of Cancer Research, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, Guangdong, China.
Zhang F; Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.
Wen H; Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.
Shi W; Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.
Huang Q; Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.
Huang Y; Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.
Xie J; Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.
Li P; Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.
Chen J; Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Qin L; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, Guangdong, China. qins_.
Zhou Y; Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2020 Jan 09; Vol. 18 (1), pp. 8. Date of Electronic Publication: 2020 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Drug Resistance, Neoplasm*/drug effects
Lung Neoplasms/*drug therapy
Mitochondria/*metabolism
Nanoparticles/*chemistry
A549 Cells ; Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Survival/drug effects ; Endocytosis/drug effects ; Female ; Humans ; Hyaluronic Acid/chemical synthesis ; Hyaluronic Acid/chemistry ; Inhibitory Concentration 50 ; Lysosomes/drug effects ; Lysosomes/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Mice, Inbred BALB C ; Micelles ; Mitochondria/drug effects ; Mitochondrial Membranes/drug effects ; Mitochondrial Membranes/metabolism ; Nanoparticles/ultrastructure ; Organophosphorus Compounds/chemical synthesis ; Organophosphorus Compounds/chemistry ; Paclitaxel/pharmacology ; Paclitaxel/therapeutic use ; Poloxamer/chemical synthesis ; Poloxamer/chemistry ; Proton Magnetic Resonance Spectroscopy ; Signal Transduction/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hierarchical self-assembly of squaraine and silica nanoparticle functionalized with cationic coordination sites for near infrared detection of ATP.
Autorzy:
Feng R; Shaanxi Key Laboratory of Natural Products &Chemical Biology, College of Chemistry &Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Shi W; Shaanxi Key Laboratory of Natural Products &Chemical Biology, College of Chemistry &Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Wang D; Shaanxi Key Laboratory of Natural Products &Chemical Biology, College of Chemistry &Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Wen J; Shaanxi Key Laboratory of Natural Products &Chemical Biology, College of Chemistry &Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Li H; Shaanxi Key Laboratory of Natural Products &Chemical Biology, College of Chemistry &Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Sun S; Shaanxi Key Laboratory of Natural Products &Chemical Biology, College of Chemistry &Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
Xu Y; Shaanxi Key Laboratory of Natural Products &Chemical Biology, College of Chemistry &Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, P. R. China.
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Źródło:
Scientific reports [Sci Rep] 2017 Feb 27; Vol. 7, pp. 43491. Date of Electronic Publication: 2017 Feb 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenosine Triphosphate*/chemistry
Cations*/chemistry
Cyclobutanes*/chemistry
Nanoparticles*/chemistry
Nanoparticles*/ultrastructure
Phenols*/chemistry
Silicon Dioxide*/chemistry
Biosensing Techniques ; Hydrogen-Ion Concentration ; Infrared Rays ; Ions ; Microscopy, Confocal ; Molecular Imaging ; Solutions
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Nanoparticle biointerfacing by platelet membrane cloaking.
Autorzy:
Hu CM; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.
Fang RH; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.
Wang KC; Department of Bioengineering, University of California, San Diego, La Jolla, California 92093, USA.; Institute of Engineering in Medicine, University of California, San Diego, La Jolla, California 92093, USA.
Luk BT; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.; Department of Bioengineering, University of California, San Diego, La Jolla, California 92093, USA.
Thamphiwatana S; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.
Dehaini D; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.
Nguyen P; Department of Bioengineering, University of California, San Diego, La Jolla, California 92093, USA.; Institute of Engineering in Medicine, University of California, San Diego, La Jolla, California 92093, USA.
Angsantikul P; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.
Wen CH; Shiley Eye Institute, University of California, San Diego, La Jolla, California 92093, USA.
Kroll AV; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.
Carpenter C; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.
Ramesh M; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.
Qu V; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.
Patel SH; Shiley Eye Institute, University of California, San Diego, La Jolla, California 92093, USA.
Zhu J; Shiley Eye Institute, University of California, San Diego, La Jolla, California 92093, USA.
Shi W; Shiley Eye Institute, University of California, San Diego, La Jolla, California 92093, USA.
Hofman FM; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.
Chen TC; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.
Gao W; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.
Zhang K; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.; Institute of Engineering in Medicine, University of California, San Diego, La Jolla, California 92093, USA.; Shiley Eye Institute, University of California, San Diego, La Jolla, California 92093, USA.; Veterans Administration Healthcare System, San Diego, California 92093, USA.
Chien S; Department of Bioengineering, University of California, San Diego, La Jolla, California 92093, USA.; Institute of Engineering in Medicine, University of California, San Diego, La Jolla, California 92093, USA.
Zhang L; Department of NanoEngineering, University of California, San Diego, La Jolla, California 92093, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA.; Institute of Engineering in Medicine, University of California, San Diego, La Jolla, California 92093, USA.
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Źródło:
Nature [Nature] 2015 Oct 01; Vol. 526 (7571), pp. 118-21. Date of Electronic Publication: 2015 Sep 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Platelet Adhesiveness*
Anti-Bacterial Agents/*administration & dosage
Blood Platelets/*cytology
Cell Membrane/*metabolism
Drug Delivery Systems/*methods
Nanoparticles/*administration & dosage
Nanoparticles/*chemistry
Animals ; Anti-Bacterial Agents/pharmacokinetics ; Blood Vessels/cytology ; Blood Vessels/metabolism ; Blood Vessels/pathology ; Collagen/chemistry ; Collagen/immunology ; Complement Activation/immunology ; Coronary Restenosis/blood ; Coronary Restenosis/drug therapy ; Coronary Restenosis/metabolism ; Disease Models, Animal ; Docetaxel ; Humans ; Macrophages/immunology ; Male ; Mice ; Polymers/chemistry ; Rats ; Rats, Sprague-Dawley ; Staphylococcal Infections/blood ; Staphylococcal Infections/drug therapy ; Staphylococcal Infections/metabolism ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/cytology ; Staphylococcus aureus/metabolism ; Taxoids/administration & dosage ; Taxoids/pharmacokinetics ; Unilamellar Liposomes/chemistry ; Vancomycin/administration & dosage ; Vancomycin/pharmacokinetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
EGFP-EGF1-conjugated PLGA nanoparticles for targeted delivery of siRNA into injured brain microvascular endothelial cells for efficient RNA interference.
Autorzy:
Chen C; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China.
Mei H
Shi W
Deng J
Zhang B
Guo T
Wang H
Hu Y
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Źródło:
PloS one [PLoS One] 2013 Apr 10; Vol. 8 (4), pp. e60860. Date of Electronic Publication: 2013 Apr 10 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nanoparticles*
RNA Interference*
Green Fluorescent Proteins/*metabolism
Lactic Acid/*chemistry
Polyglycolic Acid/*chemistry
RNA, Small Interfering/*administration & dosage
Animals ; Base Sequence ; Cells, Cultured ; Polylactic Acid-Polyglycolic Acid Copolymer ; RNA, Small Interfering/genetics ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 35

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