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    Wyświetlanie 1-19 z 19
    Tytuł:
    Machine learning determination of motivators of terminal extubation during the transition to end-of-life care in intensive care unit.
    Autorzy:
    Waldauf P; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czech Republic.
    Scales N; Ottawa Hospital Research Institute, Ottawa, ON, Canada.
    Shahin J; Faculty of Medicine, Division of Critical Care, Respiratory Epidemiology and Clinical Research Unit, McGill University Health Centre, Montreal, QC, Canada.
    Schmidt M; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czech Republic.
    van Beinum A; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
    Hornby L; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.; Canadian Donation and Transplant Research Program, Edmonton, Canada.; System Development, Canadian Blood Services, Ottawa, ON, Canada.
    Shemie SD; Pediatric Critical Care, Montreal Children's Hospital, Montreal, QC, Canada.; System Development, Canadian Blood Services, Ottawa, ON, Canada.
    Hogue M; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
    Wind TJ; Maastricht University Medical Centre and Heart and Vascular Centre, Maastricht, The Netherlands.
    van Mook W; Department of Intensive Care Medicine, Maastricht University Medical Centre, and School of Health, Maastricht, The Netherlands.
    Dhanani S; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.; Canadian Donation and Transplant Research Program, Edmonton, Canada.
    Duska F; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czech Republic. .
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    Źródło:
    Scientific reports [Sci Rep] 2023 Feb 14; Vol. 13 (1), pp. 2632. Date of Electronic Publication: 2023 Feb 14.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Ventilator Weaning*/methods
    Terminal Care*
    Humans ; Cohort Studies ; Prospective Studies ; Airway Extubation/methods ; Intensive Care Units
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The mitogenome portrait of Umbria in Central Italy as depicted by contemporary inhabitants and pre-Roman remains.
    Autorzy:
    Modi A; Department of Biology, University of Florence, 50122, Florence, Italy.
    Lancioni H; Department of Chemistry, Biology and Biotechnology, University of Perugia, 06123, Perugia, Italy. .
    Cardinali I; Department of Chemistry, Biology and Biotechnology, University of Perugia, 06123, Perugia, Italy.
    Capodiferro MR; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy.
    Rambaldi Migliore N; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy.
    Hussein A; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy.
    Strobl C; Institute of Legal Medicine, Medical University of Innsbruck, 6020, Innsbruck, Austria.
    Bodner M; Institute of Legal Medicine, Medical University of Innsbruck, 6020, Innsbruck, Austria.
    Schnaller L; Institute of Legal Medicine, Medical University of Innsbruck, 6020, Innsbruck, Austria.
    Xavier C; Institute of Legal Medicine, Medical University of Innsbruck, 6020, Innsbruck, Austria.
    Rizzi E; Istituto di Tecnologie Biomediche, CNR, Segrate, 20090, Milan, Italy.
    Bonomi Ponzi L; M.A.N.U. National Archeological Museum of Umbria, 06121, Perugia, Italy.
    Vai S; Department of Biology, University of Florence, 50122, Florence, Italy.
    Raveane A; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy.
    Cavadas B; IPATIMUP (Instituto de Patologia e Imunologia Molecular da Universidade do Porto), Porto, Portugal.; i3S (Instituto de Investigação e Inovação em Saúde, Universidade do Porto), 4200-135, Porto, Portugal.
    Semino O; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy.
    Torroni A; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy.
    Olivieri A; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy.
    Lari M; Department of Biology, University of Florence, 50122, Florence, Italy.
    Pereira L; IPATIMUP (Instituto de Patologia e Imunologia Molecular da Universidade do Porto), Porto, Portugal.; i3S (Instituto de Investigação e Inovação em Saúde, Universidade do Porto), 4200-135, Porto, Portugal.
    Parson W; Institute of Legal Medicine, Medical University of Innsbruck, 6020, Innsbruck, Austria.; Forensic Science Program, The Pennsylvania State University, University Park, PA, 16801, USA.
    Caramelli D; Department of Biology, University of Florence, 50122, Florence, Italy.
    Achilli A; Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, 27100, Pavia, Italy. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 Jul 01; Vol. 10 (1), pp. 10700. Date of Electronic Publication: 2020 Jul 01.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Demography*
    Human Migration*
    DNA, Mitochondrial/*genetics
    Genome, Mitochondrial/*genetics
    White People/*genetics
    Anthropology/methods ; Gene Pool ; Genetic Variation/genetics ; Genetics, Population/methods ; Geography ; Humans ; Italy ; Mediterranean Region ; Phylogeny
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Mapping human dispersals into the Horn of Africa from Arabian Ice Age refugia using mitogenomes.
    Autorzy:
    Gandini F; Dipartimento di Biologia e Biotecnologie 'L. Spallanzani', Università di Pavia, Pavia, Italy.; School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, UK.
    Achilli A; Dipartimento di Biologia e Biotecnologie 'L. Spallanzani', Università di Pavia, Pavia, Italy.; Dipartimento di Chimica, Biologia e Biotecnologie, Università di Perugia, Perugia, Italy.
    Pala M; School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, UK.
    Bodner M; Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria.
    Brandini S; Dipartimento di Biologia e Biotecnologie 'L. Spallanzani', Università di Pavia, Pavia, Italy.
    Huber G; Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria.
    Egyed B; Department of Genetics, Eötvös Loránd University, Budapest, Hungary.
    Ferretti L; Dipartimento di Biologia e Biotecnologie 'L. Spallanzani', Università di Pavia, Pavia, Italy.
    Gómez-Carballa A; Unidade de Xenética, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Facultade de Medicina, Universidad de Santiago de Compostela, Santiago de Compostela 15782, Galicia, Spain.
    Salas A; Unidade de Xenética, Departamento de Anatomía Patolóxica e Ciencias Forenses, and Instituto de Ciencias Forenses, Facultade de Medicina, Universidad de Santiago de Compostela, Santiago de Compostela 15782, Galicia, Spain.
    Scozzari R; Dipartimento di Biologia e Biotecnologie 'Charles Darwin', Sapienza Università di Roma, Rome, Italy.
    Cruciani F; Dipartimento di Biologia e Biotecnologie 'Charles Darwin', Sapienza Università di Roma, Rome, Italy.
    Coppa A; Dipartimento di Biologia Ambientale, Sapienza Università di Roma, Rome, Italy.
    Parson W; Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria.; Forensic Science Program, The Pennsylvania State University, University Park, Pennsylvania, USA.
    Semino O; Dipartimento di Biologia e Biotecnologie 'L. Spallanzani', Università di Pavia, Pavia, Italy.
    Soares P; CBMA (Centre of Molecular and Environmental Biology), Department of Biology, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
    Torroni A; Dipartimento di Biologia e Biotecnologie 'L. Spallanzani', Università di Pavia, Pavia, Italy.
    Richards MB; School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, UK.
    Olivieri A; Dipartimento di Biologia e Biotecnologie 'L. Spallanzani', Università di Pavia, Pavia, Italy.
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    Źródło:
    Scientific reports [Sci Rep] 2016 May 05; Vol. 6, pp. 25472. Date of Electronic Publication: 2016 May 05.
    Typ publikacji:
    Historical Article; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Flow*
    Genome, Mitochondrial*
    Phylogeny*
    Refugium*
    DNA, Mitochondrial/*genetics
    Human Migration/*history
    Africa, Eastern ; Bayes Theorem ; DNA, Mitochondrial/classification ; History, Ancient ; Human Migration/trends ; Humans ; Ice Cover ; Mediterranean Region ; Phylogeography ; Spatio-Temporal Analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Structure and immune recognition of trimeric pre-fusion HIV-1 Env.
    Autorzy:
    Pancera M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Druz A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Georgiev IS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Soto C; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Gorman J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Huang J; HIV-Specific Immunity Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Acharya P; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Chuang GY; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Ofek G; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Stewart-Jones GB; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Stuckey J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Bailer RT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Joyce MG; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Louder MK; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Tumba N; Center for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service (NHLS), Sandringham, Johannesburg 2131, South Africa.
    Yang Y; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Zhang B; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Cohen MS; Departments of Medicine, Epidemiology, Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
    Haynes BF; Duke University Human Vaccine Institute, Departments of Medicine, Surgery, Pediatrics and Immunology, Duke University School of Medicine, and the Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery at Duke University, Durham, North Carolina 27710, USA.
    Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Morris L; 1] Center for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service (NHLS), Sandringham, Johannesburg 2131, South Africa [2] University of the Witwatersrand, Braamfontein, Johannesburg 2000, South Africa [3] Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban 4041, South Africa.
    Munro JB; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut 06536, USA.
    Blanchard SC; Department of Physiology and Biophysics, Weill Cornell Medical College of Cornell University, New York, New York 10021, USA.
    Mothes W; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut 06536, USA.
    Connors M; HIV-Specific Immunity Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
    Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
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    Źródło:
    Nature [Nature] 2014 Oct 23; Vol. 514 (7523), pp. 455-61. Date of Electronic Publication: 2014 Oct 08.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    HIV Envelope Protein gp120/*chemistry
    HIV Envelope Protein gp120/*immunology
    HIV Envelope Protein gp41/*chemistry
    HIV Envelope Protein gp41/*immunology
    AIDS Vaccines/chemistry ; AIDS Vaccines/immunology ; Amino Acid Sequence ; Antibodies, Neutralizing/immunology ; Cohort Studies ; Crystallography, X-Ray ; Genetic Variation ; Glycosylation ; HIV Antibodies/immunology ; HIV Envelope Protein gp120/genetics ; HIV Envelope Protein gp41/genetics ; HIV Infections/immunology ; Humans ; Immune Evasion ; Membrane Fusion ; Models, Molecular ; Molecular Sequence Data ; Polysaccharides/chemistry ; Polysaccharides/immunology ; Protein Multimerization ; Protein Structure, Quaternary ; Protein Subunits/chemistry ; Protein Subunits/genetics ; Protein Subunits/immunology ; Structural Homology, Protein ; Virus Internalization
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    TRIM5 is an innate immune sensor for the retrovirus capsid lattice.
    Autorzy:
    Pertel T; Department of Microbiology and Molecular Medicine, University of Geneva, Geneva CH-1211, Switzerland.
    Hausmann S
    Morger D
    Züger S
    Guerra J
    Lascano J
    Reinhard C
    Santoni FA
    Uchil PD
    Chatel L
    Bisiaux A
    Albert ML
    Strambio-De-Castillia C
    Mothes W
    Pizzato M
    Grütter MG
    Luban J
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    Źródło:
    Nature [Nature] 2011 Apr 21; Vol. 472 (7343), pp. 361-5.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Capsid/*chemistry
    Capsid/*immunology
    Carrier Proteins/*immunology
    Carrier Proteins/*metabolism
    Immunity, Innate/*immunology
    Retroviridae/*immunology
    Antiviral Restriction Factors ; Carrier Proteins/genetics ; Cell Line ; Enzyme Activation ; HEK293 Cells ; HIV-1/chemistry ; HIV-1/immunology ; Humans ; Lipopolysaccharides/immunology ; Lipopolysaccharides/pharmacology ; MAP Kinase Kinase Kinases/metabolism ; NF-kappa B/metabolism ; Protein Binding ; Receptors, Pattern Recognition/immunology ; Receptors, Pattern Recognition/metabolism ; Retroviridae/chemistry ; Signal Transduction/drug effects ; Signal Transduction/immunology ; Transcription Factor AP-1/metabolism ; Transcription Factors/metabolism ; Tripartite Motif Proteins ; Ubiquitin/metabolism ; Ubiquitin-Conjugating Enzymes/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/immunology ; Ubiquitin-Protein Ligases/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population.
    Autorzy:
    Lu TT; Institut für Medizinische Informatik und Statistik, Christian-Albrechts-Universität Kiel, Kiel, Germany.
    Lao O
    Nothnagel M
    Junge O
    Freitag-Wolf S
    Caliebe A
    Balascakova M
    Bertranpetit J
    Bindoff LA
    Comas D
    Holmlund G
    Kouvatsi A
    Macek M
    Mollet I
    Nielsen F
    Parson W
    Palo J
    Ploski R
    Sajantila A
    Tagliabracci A
    Gether U
    Werge T
    Rivadeneira F
    Hofman A
    Uitterlinden AG
    Gieger C
    Wichmann HE
    Ruether A
    Schreiber S
    Becker C
    Nürnberg P
    Nelson MR
    Kayser M
    Krawczak M
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    Źródło:
    European journal of human genetics : EJHG [Eur J Hum Genet] 2009 Jul; Vol. 17 (7), pp. 967-75. Date of Electronic Publication: 2009 Jan 21.
    Typ publikacji:
    Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genome, Human*
    Genome-Wide Association Study*
    Matched-Pair Analysis*
    Polymorphism, Single Nucleotide*
    DNA/analysis ; DNA/genetics ; Europe ; Female ; Genetic Markers ; Genetic Variation ; Humans ; Male ; Population Groups/genetics ; Research Design ; Sequence Analysis, DNA
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Genetics of the Lp(a)/apo(a) system in an autochthonous Black African population from the Gabon.
    Autorzy:
    Schmidt K; Division of Human Genetics, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria.
    Kraft HG
    Parson W
    Utermann G
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    Źródło:
    European journal of human genetics : EJHG [Eur J Hum Genet] 2006 Feb; Vol. 14 (2), pp. 190-201.
    Typ publikacji:
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Quantitative Trait Loci*
    Apolipoproteins A/*blood
    Apolipoproteins A/*genetics
    Black People/*genetics
    Lipoprotein(a)/*blood
    Lipoprotein(a)/*genetics
    Adolescent ; Adult ; Child ; Electrophoresis, Polyacrylamide Gel ; Female ; Gabon ; Gene Frequency ; Humans ; Male ; Middle Aged ; Polymorphism, Genetic ; Protein Isoforms/blood ; Quantitative Trait, Heritable ; Regression Analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    A genomewide linkage analysis for prostate cancer susceptibility genes in families from Germany.
    Autorzy:
    Maier C; Abteilung Humangenetik, Universität Ulm, Germany.
    Herkommer K
    Hoegel J
    Vogel W
    Paiss T
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    Źródło:
    European journal of human genetics : EJHG [Eur J Hum Genet] 2005 Mar; Vol. 13 (3), pp. 352-60.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Genetic Linkage*
    Genetic Predisposition to Disease*
    Genome, Human*
    Prostatic Neoplasms/*genetics
    Aged ; Family Health ; Germany ; Humans ; Male ; Middle Aged ; Pedigree ; Statistics, Nonparametric
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    In NF1, CFTR, PER3, CARS and SYT7, alternatively included exons show higher conservation of surrounding intron sequences than constitutive exons.
    Autorzy:
    Kaufmann D; Department of Human Genetics, University of Ulm, Germany. />Kenner O
    Nurnberg P
    Vogel W
    Bartelt B
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    Źródło:
    European journal of human genetics : EJHG [Eur J Hum Genet] 2004 Feb; Vol. 12 (2), pp. 139-49.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alternative Splicing*
    Calcium-Binding Proteins*
    Exons*
    Introns*
    Amino Acyl-tRNA Synthetases/genetics ; Animals ; Base Sequence ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; DNA Primers ; Genes, Neurofibromatosis 1 ; Humans ; Membrane Glycoproteins/genetics ; Mice ; Nerve Tissue Proteins/genetics ; Nuclear Proteins/genetics ; Period Circadian Proteins ; Sequence Homology, Nucleic Acid ; Synaptotagmins ; Transcription Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Linkage of aggressive prostate cancer to chromosome 7q31-33 in German prostate cancer families.
    Autorzy:
    Paiss T; Department of Urology, University of Ulm, Germany.
    Wörner S
    Kurtz F
    Haeussler J
    Hautmann RE
    Gschwend JE
    Herkommer K
    Vogel W
    Pokaż więcej
    Źródło:
    European journal of human genetics : EJHG [Eur J Hum Genet] 2003 Jan; Vol. 11 (1), pp. 17-22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chromosomes, Human, Pair 7*
    Genetic Linkage*
    Genetic Predisposition to Disease*
    Prostatic Neoplasms/*genetics
    Age of Onset ; Genetic Heterogeneity ; Germany/epidemiology ; Humans ; Lod Score ; Male ; Prostatic Neoplasms/epidemiology ; Prostatic Neoplasms/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-19 z 19

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