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    Wyświetlanie 1-8 z 8
    Tytuł:
    Influence of Genetic Variations in miRNA and Genes Encoding Proteins in the miRNA Synthesis Complex on Toxicity of the Treatment of Pediatric B-Cell ALL in the Brazilian Amazon.
    Autorzy:
    da Silva Menezes E; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
    de Moraes FCA; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
    de Nazaré Cohen-Paes A; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
    Wanderley AV; Otávio Lobo Children's Cancer Hospital, Belém 66063-005, PA, Brazil.; State Department of Public Health (SESPA), Belém 66093-677, PA, Brazil.
    Pereira EEB; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.; State Department of Public Health (SESPA), Belém 66093-677, PA, Brazil.; Laboratory of Human and Medical Genetics, Institute of Biological Science, Federal University of Pará, Belém 66077-830, PA, Brazil.; Instituto Tocantinense Presidente Antônio Carlos (ITPAC), Abaetetuba 68440-000, PA, Brazil.
    Pastana LF; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
    Modesto AAC; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
    de Assumpção PP; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
    Burbano RMR; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.; Ophir Loyola Hospital, Molecular Biology Laboratory, Belém 66063-240, PA, Brazil.
    Dos Santos SEB; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.; Laboratory of Human and Medical Genetics, Institute of Biological Science, Federal University of Pará, Belém 66077-830, PA, Brazil.
    Dos Santos NPC; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
    Fernandes MR; Oncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 Feb 23; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 23.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    MicroRNAs*/genetics
    Precursor B-Cell Lymphoblastic Leukemia-Lymphoma*
    Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics
    Humans ; Child ; Brazil ; Polymorphism, Single Nucleotide
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Performance of PRISM III and PIM 2 scores in a cancer pediatric intensive care unit.
    Autorzy:
    Farias ECF; Unidade de Terapia Intensiva Pediátrica, Hospital Oncológico Infantil Octávio Lobo - Belém (PA), Brasil.
    Mello MLFMF; Unidade de Terapia Intensiva Pediátrica, Hospital Oncológico Infantil Octávio Lobo - Belém (PA), Brasil.
    Assunção PBC; Unidade de Terapia Intensiva Pediátrica, Hospital Oncológico Infantil Octávio Lobo - Belém (PA), Brasil.
    Wanderley AV; Unidade de Oncologia Pediátrica, Hospital Oncológico Infantil Octávio Lobo - Belém (PA), Brasil.
    Ferraro KMMM; Unidade de Terapia Intensiva Pediátrica, Fundação Santa Casa de Misericórdia - Belém (PA), Brasil.
    Machado MMM; Universidade Federal do Pará - Belém (PA), Brasil.
    Marinho SJ; Universidade Federal do Pará - Belém (PA), Brasil.
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    Transliterated Title:
    Desempenho do PRISM III e do PIM 2 em unidade de terapia intensiva pediátrica oncológica.
    Źródło:
    Revista Brasileira de terapia intensiva [Rev Bras Ter Intensiva] 2021 Jan-Mar; Vol. 33 (1), pp. 119-124.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Critical Illness*
    Neoplasms*
    Child ; Hospital Mortality ; Humans ; Infant ; Intensive Care Units, Pediatric ; Prospective Studies ; Retrospective Studies ; Severity of Illness Index
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia.
    Autorzy:
    Moreira-Nunes CA; Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Coronel Nunes de Melo st, n 1000, Rodolfo Teófilo, Fortaleza, CE, CEP: 60416-000, Brazil. .
    Mesquita FP; Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Coronel Nunes de Melo st, n 1000, Rodolfo Teófilo, Fortaleza, CE, CEP: 60416-000, Brazil.
    Portilho AJS; Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Coronel Nunes de Melo st, n 1000, Rodolfo Teófilo, Fortaleza, CE, CEP: 60416-000, Brazil.
    Mello Júnior FAR; Molecular Biology Laboratory, Ophir Loyola Hospital, Belém, PA, Brazil.
    Maués JHDS; Laboratory of Human Cytogenetics, Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
    Pantoja LDC; Department of Pediatrics, Octávio Lobo Children's Hospital, Belém, PA, Brazil.
    Wanderley AV; Department of Pediatrics, Octávio Lobo Children's Hospital, Belém, PA, Brazil.
    Khayat AS; Oncology Research Center, João de Barros Barreto University Hospital, Federal University of Pará, Belém, PA, Brazil.
    Zuercher WJ; Division of Chemical Biology and Medicinal Chemistry, University of North Carolina at Chapel Hill, Eshelman School of Pharmacy, Chapel Hill, NC, USA.
    Montenegro RC; Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Coronel Nunes de Melo st, n 1000, Rodolfo Teófilo, Fortaleza, CE, CEP: 60416-000, Brazil.
    de Moraes-Filho MO; Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Coronel Nunes de Melo st, n 1000, Rodolfo Teófilo, Fortaleza, CE, CEP: 60416-000, Brazil.
    de Moraes MEA; Pharmacogenetics Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Coronel Nunes de Melo st, n 1000, Rodolfo Teófilo, Fortaleza, CE, CEP: 60416-000, Brazil.
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    Źródło:
    Scientific reports [Sci Rep] 2020 Dec 04; Vol. 10 (1), pp. 21272. Date of Electronic Publication: 2020 Dec 04.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Aurora Kinase A/*metabolism
    Aurora Kinase B/*metabolism
    Precursor Cell Lymphoblastic Leukemia-Lymphoma/*enzymology
    Biomarkers, Tumor/metabolism ; Brazil/epidemiology ; Case-Control Studies ; Child ; Child, Preschool ; Female ; Fusion Proteins, bcr-abl/metabolism ; Humans ; Infant ; K562 Cells ; Male ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/mortality ; Protein Interaction Maps
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Identifying novel genetic alterations in pediatric acute lymphoblastic leukemia based on copy number analysis.
    Autorzy:
    Batista-Gomes JA; Oncology Research Center, Federal University of Pará, Belém, Brazil.
    Mello FAR Jr; Oncology Research Center, Federal University of Pará, Belém, Brazil.
    de Oliveira EHC; Cell culture and Cytogenetic Laboratory, Evandro Chagas Institute, Ananindeua, Brazil.
    de Souza MPC; Cell culture and Cytogenetic Laboratory, Evandro Chagas Institute, Ananindeua, Brazil.
    Wanderley AV; Octávio Lobo Children's Cancer Hospital, Belém, Brazil.
    da Costa Pantoja L; Octávio Lobo Children's Cancer Hospital, Belém, Brazil.
    Dos Santos NPC; Oncology Research Center, Federal University of Pará, Belém, Brazil.
    Khayat BCM; Oncology Research Center, Federal University of Pará, Belém, Brazil.
    Khayat AS; Oncology Research Center, Federal University of Pará, Belém, Brazil.
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    Źródło:
    Molecular cytogenetics [Mol Cytogenet] 2020 Jun 26; Vol. 13, pp. 25. Date of Electronic Publication: 2020 Jun 26 (Print Publication: 2020).
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Characterization of pharmacogenetic markers related to Acute Lymphoblastic Leukemia toxicity in Amazonian native Americans population.
    Autorzy:
    de Carvalho DC; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    Wanderley AV; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.; Departamento de Pediatria, Ophir Loyola Hospital, Belém, PA, Brazil.
    Dos Santos AMR; Human and Medical Genetics Laboratory, Instituto de Ciências Biológicas, Universidade Federal Do Pará, Belém, PA, Brazil.
    Moreira FC; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    de Sá RBA; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    Fernandes MR; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    Modesto AAC; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    de Souza TP; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    Cohen-Paes A; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    Leitão LPC; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    Rodrigues JCG; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    da Silva ALDC; Genomics and Bioinformatics Laboratory, Instituto de Ciências Biológicas, Universidade Federal Do Pará, Belém, Brazil.
    Guerreiro JF; Human and Medical Genetics Laboratory, Instituto de Ciências Biológicas, Universidade Federal Do Pará, Belém, PA, Brazil.
    Santos S; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.; Human and Medical Genetics Laboratory, Instituto de Ciências Biológicas, Universidade Federal Do Pará, Belém, PA, Brazil.
    Khayat AS; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.
    de Assumpção PP; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil.; João de Barros Barreto University Hospital, Universidade Federal Do Pará, Belém, PA, Brazil.
    Dos Santos NPC; Oncology Research Nucleus, Universidade Federal Do Pará, Belém, PA, Brazil. .; Human and Medical Genetics Laboratory, Instituto de Ciências Biológicas, Universidade Federal Do Pará, Belém, PA, Brazil. .; Hospital Universitário João de Barros Barreto - Núcleo de Pesquisa Em Oncologia, 2º Piso da Unidade de Alta Complexidade Em Oncologia. Av. Mundurucus, 4487, Guamá, Belém, PA, 66073-005, Brazil. .
    Pokaż więcej
    Źródło:
    Scientific reports [Sci Rep] 2020 Jun 24; Vol. 10 (1), pp. 10292. Date of Electronic Publication: 2020 Jun 24.
    Typ publikacji:
    Journal Article; Observational Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Pharmacogenomic Variants*
    Antineoplastic Agents/*pharmacology
    Indians, South American/*genetics
    Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
    Antineoplastic Agents/therapeutic use ; Brazil ; Child ; Child, Preschool ; Female ; Genetic Markers ; Humans ; Male ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Identification of NUDT15 gene variants in Amazonian Amerindians and admixed individuals from northern Brazil.
    Autorzy:
    Rodrigues JCG; Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil.
    Souza TP; Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil.
    Pastana LF; Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil.
    Ribeiro Dos Santos AM; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Fernandes MR; Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil.
    Pinto P; Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil.; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Wanderley AV; Hospital Ophir Loyola, Departamento de Pediatria, Belém, Pará, Brazil.
    Souza SJ; Brain Institute, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
    Kroll JE; Brain Institute, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
    Pereira AL; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Magalhães L; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Mercês LRD; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Vidal AF; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Vinasco-Sandoval T; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Cavalcante GC; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Guerreiro JF; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Assumpção PP; Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil.
    Ribeiro-Dos-Santos Â; Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil.; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Santos S; Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil.; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
    Santos NPCD; Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil.; Laboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
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    Źródło:
    PloS one [PLoS One] 2020 Apr 15; Vol. 15 (4), pp. e0231651. Date of Electronic Publication: 2020 Apr 15 (Print Publication: 2020).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Indigenous Peoples/*genetics
    Pyrophosphatases/*genetics
    Antimetabolites, Antineoplastic/pharmacology ; Antimetabolites, Antineoplastic/therapeutic use ; Brazil ; Humans ; Mercaptopurine/pharmacology ; Mercaptopurine/therapeutic use ; Polymorphism, Single Nucleotide ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Pyrophosphatases/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-8 z 8

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