Autor: "Wang, Hong‐Yang" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Development of a TMErisk model based on immune infiltration in tumour microenvironment to predict prognosis of immune checkpoint inhibitor treatment in hepatocellular carcinoma.
Autorzy:: Yan ZJ; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital/National Center for Liver Cancer, Shanghai 200438, PR. China.; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education. Shanghai 200438, PR. China.; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai 200438, PR. China.
Yu CT; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital/National Center for Liver Cancer, Shanghai 200438, PR. China.; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education. Shanghai 200438, PR. China.; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai 200438, PR. China.
Chen L; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital/National Center for Liver Cancer, Shanghai 200438, PR. China.; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education. Shanghai 200438, PR. China.; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai 200438, PR. China.
Wang HY; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital/National Center for Liver Cancer, Shanghai 200438, PR. China.; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education. Shanghai 200438, PR. China.; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai 200438, PR. China.; Pokaż więcej
Źródło:: Briefings in bioinformatics [Brief Bioinform] 2023 Mar 19; Vol. 24 (2).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Hepatocellular*/drug therapy
Liver Neoplasms*/drug therapy
Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Tumor Microenvironment ; Immunotherapy

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Skocz do pozycji: 2.

Tytuł:: The development of a cSMART-based integrated model for hepatocellular carcinoma diagnosis.
Autorzy:: Wu T; International Cooperation Laboratory on Signal Transduction, National Center for Liver Cancer, Eastern Hepatobiliary Surgery Institute/hospital, Shanghai, 200438, People's Republic of China.; Department of Radiotherapy Oncology, General Hospital of Northern Theater Command, Shenyang, 110016, People's Republic of China.
Fan R; Department of Infectious Diseases, State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.; Hepatology Unit, Shenzhen Hospital, Southern Medical University, Shenzhen, People's Republic of China.
Bai J; Berry Oncology Corporation, Beijing, 100102, People's Republic of China.
Yang Z; Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, 200438, People's Republic of China.
Qian YS; Hepatology Department, Ningbo Hwamei Hospital, University of Chinese Academy of Sciences, Ningbo, 315010, People's Republic of China.
Du LT; Department of Clinical Laboratory, The Second Hospital, Cheeloo College of Medicine, Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, People's Republic of China.; Shandong Provincial Clinical Medicine Research Center for Clinical Laboratory, Jinan, 250033, People's Republic of China.
Wang CY; Xuzhou Infectious Diseases Hospital, Xuzhou, 221004, People's Republic of China.
Wang YC; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, 350025, People's Republic of China.
Jiang GQ; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, 225001, People's Republic of China.
Zheng D; Department of Gastroenterology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, People's Republic of China.
Fan XT; Department of Hepatology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, People's Republic of China.
Zheng B; International Cooperation Laboratory on Signal Transduction, National Center for Liver Cancer, Eastern Hepatobiliary Surgery Institute/hospital, Shanghai, 200438, People's Republic of China.
Liu JF; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, 350025, People's Republic of China.
Deng GH; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, People's Republic of China.
Shen F; Department of Hepatic Surgery IV, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, 200438, People's Republic of China.
Hu HP; Department of Hepatobiliary Medicine, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, 210822, People's Republic of China.
Ye YN; The Department of Infectious Disease, The First People's Hospital of Foshan, Foshan City, 528000, People's Republic of China.
Zhang QZ; Berry Oncology Corporation, Beijing, 100102, People's Republic of China.
Zhang J; Berry Oncology Corporation, Beijing, 100102, People's Republic of China.
Gao YH; The First Hospital of Jilin University, Jilin, 130021, People's Republic of China.
Xia J; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, People's Republic of China.
Yan HD; Hepatology Department, Ningbo Hwamei Hospital, University of Chinese Academy of Sciences, Ningbo, 315010, People's Republic of China.
Liang MF; The Department of Infectious Disease, The First People's Hospital of Foshan, Foshan City, 528000, People's Republic of China.
Yu YL; Chifeng Clinical Medical School of Inner, Mongolia Medical University, Chifeng, 024000, People's Republic of China.
Sun FM; Berry Oncology Corporation, Beijing, 100102, People's Republic of China.
Gao YJ; Xuzhou Infectious Diseases Hospital, Xuzhou, 221004, People's Republic of China.
Sun J; Department of Infectious Diseases, State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Zhong CX; Department of Infectious Diseases, State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Wang Y; Berry Oncology Corporation, Beijing, 100102, People's Republic of China.
Wang H; Department of Hepatobiliary Medicine, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, 210822, People's Republic of China.
Kong F; The First Hospital of Jilin University, Jilin, 130021, People's Republic of China.
Chen JM; Chifeng Clinical Medical School of Inner, Mongolia Medical University, Chifeng, 024000, People's Republic of China.
Wen H; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, People's Republic of China.
Wu BM; Hepatology Department, Ningbo Hwamei Hospital, University of Chinese Academy of Sciences, Ningbo, 315010, People's Republic of China.
Wang CX; Department of Clinical Laboratory, The Second Hospital, Cheeloo College of Medicine, Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, People's Republic of China.; Shandong Provincial Clinical Medicine Research Center for Clinical Laboratory, Jinan, 250033, People's Republic of China.
Wu L; Berry Oncology Corporation, Beijing, 100102, People's Republic of China.
Hou JL; Department of Infectious Diseases, State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.; Hepatology Unit, Shenzhen Hospital, Southern Medical University, Shenzhen, People's Republic of China.
Liu XL; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, 350025, People's Republic of China. .
Wang HY; International Cooperation Laboratory on Signal Transduction, National Center for Liver Cancer, Eastern Hepatobiliary Surgery Institute/hospital, Shanghai, 200438, People's Republic of China. .; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education, Shanghai, 200438, People's Republic of China. .; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai, 200438, People's Republic of China. .
Chen L; International Cooperation Laboratory on Signal Transduction, National Center for Liver Cancer, Eastern Hepatobiliary Surgery Institute/hospital, Shanghai, 200438, People's Republic of China. .; Pokaż więcej
Źródło:: Journal of hematology & oncology [J Hematol Oncol] 2023 Jan 05; Vol. 16 (1), pp. 1. Date of Electronic Publication: 2023 Jan 05.
Typ publikacji:: Multicenter Study; Letter; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Hepatocellular*/diagnosis
Carcinoma, Hepatocellular*/genetics
Liver Neoplasms*/diagnosis
Liver Neoplasms*/genetics
Humans ; alpha-Fetoproteins ; Biomarkers, Tumor/genetics ; Liver Cirrhosis/diagnosis

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Skocz do pozycji: 3.

Tytuł:: Novel transketolase inhibitor oroxylin A suppresses the non-oxidative pentose phosphate pathway and hepatocellular carcinoma tumour growth in mice and patient-derived organoids.
Autorzy:: Jia D; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.; National Center for Liver Cancer, Second Military Medical University/Naval Medical University, Shanghai, China.; Department of Biochemistry and Molecular Biology, College of Basic Medical, Second Military Medical University/Naval Medical University, Shanghai, China.
Liu C; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.
Zhu Z; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.
Cao Y; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.
Wen W; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.; National Center for Liver Cancer, Second Military Medical University/Naval Medical University, Shanghai, China.
Hong Z; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.
Liu Y; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.
Liu E; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.; National Center for Liver Cancer, Second Military Medical University/Naval Medical University, Shanghai, China.
Chen L; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.
Chen C; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.; Department of Pharmacy, Shanghai Ninth People's Hospital, School of Medicine of Shanghai Jiao Tong University, Shanghai, China.
Gu Y; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.; Department of Pharmacy, Shanghai Ninth People's Hospital, School of Medicine of Shanghai Jiao Tong University, Shanghai, China.
Jiao B; Department of Biochemistry and Molecular Biology, College of Basic Medical, Second Military Medical University/Naval Medical University, Shanghai, China.
Chai Y; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.
Wang HY; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.; National Center for Liver Cancer, Second Military Medical University/Naval Medical University, Shanghai, China.
Fu J; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.; National Center for Liver Cancer, Second Military Medical University/Naval Medical University, Shanghai, China.
Chen X; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.; School of Pharmacy, Second Military Medical University/Naval Medical University, Shanghai, China.; National Center for Liver Cancer, Second Military Medical University/Naval Medical University, Shanghai, China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2022 Nov; Vol. 12 (11), pp. e1095.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Humans ; Animals ; Mice ; Transketolase/genetics ; Transketolase/metabolism ; Pentose Phosphate Pathway ; Organoids/metabolism ; Organoids/pathology ; Molecular Docking Simulation

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Skocz do pozycji: 4.

Tytuł:: 4-phenylbutyric acid promotes hepatocellular carcinoma via initiating cancer stem cells through activation of PPAR-α.
Autorzy:: Chen SZ; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Ling Y; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Yu LX; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Song YT; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.; Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
Chen XF; School of Pharmacy, Second Military Medical University, Shanghai, China.
Cao QQ; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Yu H; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Chen C; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.; Fujian Medical University, Fuzhou, Fujian Province, China.
Tang JJ; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; Cancer Research Center, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui Province, China.
Fan ZC; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.
Miao YS; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Dong YP; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.; Fujian Medical University, Fuzhou, Fujian Province, China.
Tao JY; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Monga SPS; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Wen W; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Wang HY; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.; Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.; Fujian Medical University, Fuzhou, Fujian Province, China.; Cancer Research Center, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui Province, China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2021 Apr; Vol. 11 (4), pp. e379.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Hepatocellular/*chemically induced
Liver Neoplasms/*chemically induced
Neoplastic Stem Cells/*drug effects
PPAR alpha/*metabolism
Phenylbutyrates/*pharmacology
Animals ; Carcinogenesis/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Nude ; Wnt Signaling Pathway/drug effects