Autor: "Wang, Shan-Jin" - OpacWWW

Skocz do pozycji: 1 1.

Tytuł :: Leptin regulates disc cartilage endplate degeneration and ossification through activation of the MAPK-ERK signalling pathway in vivo and in vitro.
Autorzy :: Han YC; Department of Orthopedics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Ma B; Department of Orthopedics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Guo S; Department of Orthopedics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yang M; Department of Orthopedics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Li LJ; Department of Orthopedics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Wang SJ; Department of Spinal Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Tan J; Department of Orthopedics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.; Pokaż więcej
Źródło :: Journal of cellular and molecular medicine [J Cell Mol Med] 2018 Apr; Vol. 22 (4), pp. 2098-2109. Date of Electronic Publication: 2018 Jan 26.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: MAP Kinase Signaling System*/drug effects
Cartilage/*enzymology
Cartilage/*pathology
Intervertebral Disc Degeneration/*enzymology
Intervertebral Disc Degeneration/*pathology
Leptin/*pharmacology
Osteogenesis/*drug effects
Animals ; Calcification, Physiologic/drug effects ; Cartilage/drug effects ; Cell Differentiation/drug effects ; Core Binding Factor Alpha 1 Subunit/metabolism ; Disease Models, Animal ; Lumbar Vertebrae/drug effects ; Lumbar Vertebrae/pathology ; Male ; Motor Endplate/drug effects ; Motor Endplate/pathology ; Osteocalcin/metabolism ; Phosphorylation/drug effects ; Rats, Sprague-Dawley ; STAT3 Transcription Factor/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: Leptin induces osteocalcin expression in ATDC5 cells through activation of the MAPK-ERK1/2 signaling pathway.
Autorzy :: Han Y; Department of Spine Surgery, Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, 200120, China.
Xu G; Department of Orthopedics, Shanghai Zhabei District Central hospital, Zhonghuaxin Road Zhabei District, Shanghai, 200070, China.
Zhang J; Department of Spine Surgery, Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, 200120, China.
Yan M; Department of Spine Surgery, Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, 200120, China.
Li X; Department of Spine Surgery, Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, 200120, China.
Ma B; Department of Spine Surgery, Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, 200120, China.
Jun L; Department of Spine Surgery, Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, 200120, China.
Wang SJ; Department of Spine Surgery, Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, 200120, China.
Tan J; Department of Spine Surgery, Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, 200120, China.; Pokaż więcej
Źródło :: Oncotarget [Oncotarget] 2016 Sep 27; Vol. 7 (39), pp. 64021-64029.
Typ publikacji :: Journal Article
MeSH Terms :: MAP Kinase Signaling System*
Chondrocytes/*cytology
Extracellular Signal-Regulated MAP Kinases/*metabolism
Leptin/*metabolism
Osteocalcin/*metabolism
Animals ; Butadienes/chemistry ; Cell Count ; Cell Differentiation ; Cell Line ; Chondrogenesis/drug effects ; Mice ; Mitogen-Activated Protein Kinase 3/metabolism ; Mitogen-Activated Protein Kinases/metabolism ; Nitriles/chemistry ; Osteoblasts/cytology ; Osteocalcin/blood ; Osteogenesis/drug effects ; Phosphorylation ; RNA, Small Interfering/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 3 3.

Tytuł :: Stage specific effect of leptin on the expressions of estrogen receptor and extracellular matrix in a model of chondrocyte differentiation.
Autorzy :: Li XF; Department of Orthopaedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Wang SJ
Jiang LS
Dai LY; Pokaż więcej
Źródło :: Cytokine [Cytokine] 2013 Mar; Vol. 61 (3), pp. 876-84. Date of Electronic Publication: 2013 Jan 26.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Models, Biological*
Cell Differentiation/*genetics
Chondrocytes/*cytology
Estrogen Receptor alpha/*genetics
Estrogen Receptor beta/*genetics
Extracellular Matrix/*metabolism
Leptin/*pharmacology
Animals ; Cell Differentiation/drug effects ; Chondrocytes/drug effects ; Chondrocytes/metabolism ; Chondrogenesis/drug effects ; Chondrogenesis/genetics ; Collagen Type II/genetics ; Collagen Type II/metabolism ; Collagen Type X/genetics ; Collagen Type X/metabolism ; Estrogen Receptor alpha/metabolism ; Estrogen Receptor beta/metabolism ; Extracellular Matrix/drug effects ; Mice ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Leptin/genetics ; Receptors, Leptin/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: Leptin regulates estrogen receptor gene expression in ATDC5 cells through the extracellular signal regulated kinase signaling pathway.
Autorzy :: Wang SJ; Department of Orthopedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Li XF
Jiang LS
Dai LY; Pokaż więcej
Źródło :: Journal of cellular biochemistry [J Cell Biochem] 2012 Apr; Vol. 113 (4), pp. 1323-32.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Signal Transduction*
Estrogen Receptor alpha/*genetics
Estrogen Receptor beta/*genetics
Extracellular Signal-Regulated MAP Kinases/*metabolism
Leptin/*physiology
Animals ; Base Sequence ; Blotting, Western ; Cell Differentiation ; Cell Line ; DNA Primers ; Estrogen Receptor alpha/metabolism ; Estrogen Receptor beta/metabolism ; Mice ; RNA, Messenger/genetics ; Real-Time Polymerase Chain Reaction ; p38 Mitogen-Activated Protein Kinases/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: Leptin regulates disc cartilage endplate degeneration and ossification through activation of the MAPK‐ERK signalling pathway in vivo and in vitro.
Autorzy :: Han, Ying‐Chao
Ma, Bin
Guo, Song
Yang, Mingjie
Li, Li‐Jun
Wang, Shan‐Jin
Tan, Jun; Pokaż więcej
Temat :: OSTEOBLASTS
CELL differentiation
MITOGEN-activated protein kinases
DEGENERATION (Pathology)
OSTEOCALCIN
LEPTIN
CELLULAR signal transduction
Źródło :: Journal of Cellular & Molecular Medicine; Apr2018, Vol. 22 Issue 4, p2098-2109, 12p
: Czasopismo naukowe

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