- Tytuł:
- IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.
- Autorzy:
- Źródło:
- Nature [Nature] 2012 Feb 15; Vol. 483 (7390), pp. 479-83. Date of Electronic Publication: 2012 Feb 15.
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Phenotype*
DNA Methylation/*genetics
Glioma/*geneticsIsocitrate Dehydrogenase /*genetics
Mutation/*genetics
Astrocytes/cytology ; Astrocytes/metabolism ; Cell Survival/genetics ; Cells, Cultured ; CpG Islands/genetics ; Epigenesis, Genetic ; Epigenomics ; Gene Expression Regulation ; Glioblastoma/genetics ; Glioblastoma/pathology ; Glioma/pathology ; HEK293 Cells ; Histones/metabolism ; Humans ;Isocitrate Dehydrogenase /metabolism ; Metabolome/genetics ; Tumor Cells, Cultured
Czasopismo naukowe