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Tytuł:
Activation of Metabotropic Glutamate Receptor (mGlu 2 ) and Muscarinic Receptors (M 1 , M 4 , and M 5 ), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis.
Autorzy:
Wierońska JM; Maj Institute of Pharmacology Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland.
Cieślik P; Maj Institute of Pharmacology Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland.
Burnat G; Maj Institute of Pharmacology Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland.
Kalinowski L; Department of Medical Laboratory Diagnostics-Fahrenheit Biobank BBMRI.pl, Medical University of Gdansk, 7 Debinki Street, 80-211 Gdansk, Poland.; BioTechMed Centre, Department of Mechanics of Materials and Structures, Gdansk University of Technology, 11/12 Gabriela Narutowicza Street, 80-233 Gdansk, Poland.
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Źródło:
Biomolecules [Biomolecules] 2023 Jun 30; Vol. 13 (7). Date of Electronic Publication: 2023 Jun 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dizocilpine Maleate*/pharmacology
Receptors, Metabotropic Glutamate*/metabolism
Animals ; Glutamic Acid ; N-Methylaspartate ; Morris Water Maze Test ; Receptors, Muscarinic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chronic Cyanuric Acid Exposure Depresses Hippocampal LTP but Does Not Disrupt Spatial Learning or Memory in the Morris Water Maze.
Autorzy:
Sun W; Department of Pediatric, The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, 550001, China.; Behavioral Neuroscience Laboratory, The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, 550001, China.
Yang Y; Department of Pediatric, The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, 550001, China. .
Wu Z; Department of Pediatric, The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, 550001, China.
Chen X; Behavioral Neuroscience Laboratory, The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, 550001, China.
Li W; Department of Neurology, Jinan Geriatric/Rehabilitation Hospital, Jinan, 250013, China.
An L; Department of Pediatric, The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, 550001, China. al_.; Behavioral Neuroscience Laboratory, The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, 550001, China. al_.
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Źródło:
Neurotoxicity research [Neurotox Res] 2021 Aug; Vol. 39 (4), pp. 1148-1159. Date of Electronic Publication: 2021 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Hippocampus/*drug effects
Long-Term Potentiation/*drug effects
Morris Water Maze Test/*drug effects
Spatial Learning/*drug effects
Spatial Memory/*drug effects
Triazines/*toxicity
Animals ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Hippocampus/physiology ; Long-Term Potentiation/physiology ; Male ; Morris Water Maze Test/physiology ; Organ Culture Techniques ; Rats ; Rats, Sprague-Dawley ; Spatial Learning/physiology ; Spatial Memory/physiology ; Triazines/administration & dosage
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Genes associated with cognitive performance in the Morris water maze: an RNA-seq study.
Autorzy:
Reshetnikov VV; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk, Russia.
Kisaretova PE; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk, Russia.
Ershov NI; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk, Russia.
Shulyupova AS; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk, Russia.
Oshchepkov DY; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk, Russia.
Klimova NV; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk, Russia.
Ivanchihina AV; Novosibirsk State University, Novosibirsk, Russia.
Merkulova TI; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk, Russia.
Bondar NP; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (SB RAS), Novosibirsk, Russia. .; Novosibirsk State University, Novosibirsk, Russia. .
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Źródło:
Scientific reports [Sci Rep] 2020 Dec 16; Vol. 10 (1), pp. 22078. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cognition*
Gene Expression Regulation*
Hippocampus*
Morris Water Maze Test*
RNA-Seq*
Synaptic Transmission/*genetics
Animals ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of different protocols of Morris water maze in cognitive impairment with heart failure.
Autorzy:
Lu Z; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yang T; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Wang L; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Qiu Q; Department of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Zhao Y; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Wu A; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Li T; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Cheng W; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Wang B; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Li Y; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yang J; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Zhao M; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
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Źródło:
Brain and behavior [Brain Behav] 2020 Feb; Vol. 10 (2), pp. e01519. Date of Electronic Publication: 2020 Jan 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cognitive Dysfunction*/physiopathology
Cognitive Dysfunction*/psychology
Morris Water Maze Test*
Cognition/*physiology
Heart Failure/*psychology
Animals ; Behavior, Animal/physiology ; Memory, Short-Term ; Rats ; Rats, Sprague-Dawley ; Reversal Learning ; Spatial Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nootropic Effects of 7-Isoprenyloxycoumarin and Herniarin from Tagetes lucida on Lipopolysaccharide-Induced Neuroinflammation
Autorzy:
Monterrosas-Brisson, Nayeli
Jiménez-Ferrer, Enrique
Bahena-Pérez, RafaelAff1, Aff2
González-Cortazar, Manases
Porras-Dávila, Sandra Liliana
Tapia-Maruri, Daniel
Martínez-Duncker, Iván
Herrera-Ruiz, MaribelAff2, IDs43450024005187_cor8
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Źródło:
Revista Brasileira de Farmacognosia: Brazilian Journal of Pharmacognosy. :1-12
Czasopismo naukowe
Szczegóły
Tytuł:
THE EFFECT OF A MODIFIED FRAGMENT OF NEUROPEPTIDE Y ON SPATIAL MEMORY AND LEARNING IN THE MORRIS WATER MAZE.
Autorzy:
Havrylov, Ihnat
Shtrygol', Sergіy
Kavraiskyi, Dmytryi
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Alternatywny tytuł:
ВПЛИВ МОДИФІКОВАННОГО ФРАГМЕНТУ НЕЙРОПЕПТИДУ Y НА ПРОСТОРОВУ ПАМ'ЯТЬ ТА НАВЧАННЯ У ВОДНОМУ ЛАБІРИНТІ МОРРІСА (с. 22-27)
Źródło:
ScienceRise: Pharmaceutical Science. 2022, Vol. 35 Issue 1, p22-27. 6p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits.
Autorzy:
Curdt N; Department of Psychiatry and Psychotherapy, Division of Molecular Psychiatry, Georg-August-University Göttingen, University Medicine Göttingen, 37075, Göttingen, Germany.
Schmitt FW; Department of Psychiatry and Psychotherapy, Division of Molecular Psychiatry, Georg-August-University Göttingen, University Medicine Göttingen, 37075, Göttingen, Germany.
Bouter C; Department of Nuclear Medicine, University Medical Center Göttingen (UMG), Georg-August-University, Göttingen, Germany.
Iseni T; Department of Psychiatry and Psychotherapy, Division of Molecular Psychiatry, Georg-August-University Göttingen, University Medicine Göttingen, 37075, Göttingen, Germany.
Weile HC; Department of Psychiatry and Psychotherapy, Division of Molecular Psychiatry, Georg-August-University Göttingen, University Medicine Göttingen, 37075, Göttingen, Germany.
Altunok B; Department of Psychiatry and Psychotherapy, Division of Molecular Psychiatry, Georg-August-University Göttingen, University Medicine Göttingen, 37075, Göttingen, Germany.
Beindorff N; Berlin Experimental Radionuclide Imaging Center (BERIC), Charité-University Medicine Berlin, Berlin, Germany.
Bayer TA; Department of Psychiatry and Psychotherapy, Division of Molecular Psychiatry, Georg-August-University Göttingen, University Medicine Göttingen, 37075, Göttingen, Germany.
Cooke MB; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada.; Department of Psychology, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.
Bouter Y; Department of Psychiatry and Psychotherapy, Division of Molecular Psychiatry, Georg-August-University Göttingen, University Medicine Göttingen, 37075, Göttingen, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2022 Mar 31; Vol. 12 (1), pp. 5451. Date of Electronic Publication: 2022 Mar 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease*
Spatial Navigation*
Animals ; Female ; Maze Learning ; Mice ; Morris Water Maze Test ; Spatial Memory
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Influence of diurnal phase on behavioral tests of sensorimotor performance, anxiety, learning and memory in mice.
Autorzy:
Tsao CH; Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan.
Flint J; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Huang GJ; Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan. .; Department of Neurology, Chang Gung Memorial Hospital-Linkou Medical Center, Taoyuan 333, Taiwan. .; Healthy Aging Research Center, Chang Gung University, Taoyuan, 33302, Taiwan. .; Molecular Medicine Research Center, Chang Gung University, Taoyuan, 33302, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 10; Vol. 12 (1), pp. 432. Date of Electronic Publication: 2022 Jan 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anxiety*
Circadian Rhythm*
Psychomotor Performance*
Memory/*physiology
Spatial Learning/*physiology
Animals ; Avoidance Learning ; Female ; Male ; Mice, Inbred C57BL ; Morris Water Maze Test ; Sex Characteristics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structure-activity relationship, in vitro and in vivo evaluation of novel dienyl sulphonyl fluorides as selective BuChE inhibitors for the treatment of Alzheimer's disease.
Autorzy:
Wu C; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China.
Zhang G; Management Center of Anhui Continuing Education Network Park, Anhui Open University, Hefei, China.
Zhang ZW; School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan, China.
Jiang X; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China.
Zhang Z; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China.
Li H; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China.
Qin HL; School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan, China.
Tang W; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 1860-1873.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease/*drug therapy
Cholinesterase Inhibitors/*chemistry
Cholinesterases/*metabolism
Neuroprotective Agents/*chemistry
Sulfinic Acids/*chemistry
Alkynes/chemistry ; Amyloid/metabolism ; Animals ; Behavior, Animal ; Blood-Brain Barrier/metabolism ; Cell Survival/drug effects ; Cholinesterase Inhibitors/pharmacology ; Drug Design ; Humans ; Liver ; Male ; Mice, Inbred ICR ; Molecular Docking Simulation ; Molecular Structure ; Morris Water Maze Test ; Nervous System ; Neuroprotective Agents/pharmacology ; Structure-Activity Relationship ; Sulfinic Acids/pharmacology ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Luteolin Suppresses Microglia Neuroinflammatory Responses and Relieves Inflammation-Induced Cognitive Impairments.
Autorzy:
Zhou W; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, 100 Waihuanxi Road, Guangzhou, 510006, PR China.
Hu M; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, 100 Waihuanxi Road, Guangzhou, 510006, PR China.
Hu J; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, 100 Waihuanxi Road, Guangzhou, 510006, PR China.
Du Z; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, 100 Waihuanxi Road, Guangzhou, 510006, PR China.
Su Q; School of Computers, Guangdong University of Technology, 100 Waihuanxi Road, Guangzhou, 510006, PR China. .
Xiang Z; Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Guangdong Institute of Analysis, Guangzhou, 510070, PR China. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2021 Dec; Vol. 39 (6), pp. 1800-1811. Date of Electronic Publication: 2021 Oct 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cognitive Dysfunction/*drug therapy
Luteolin/*therapeutic use
Microglia/*drug effects
Neuroinflammatory Diseases/*drug therapy
Animals ; Blotting, Western ; Cell Line ; Cognitive Dysfunction/etiology ; Enzyme-Linked Immunosorbent Assay ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Morris Water Maze Test ; Neuroinflammatory Diseases/complications
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Preclinical validation of a novel oral Edaravone formulation for treatment of frontotemporal dementia.
Autorzy:
Kelliny S; Health and Biomedical Innovation, Clinical and Health Sciences, University of South Australia, Adelaide, SA, 5000, Australia.; Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Xiong J; Department of Neurology, The Second Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, China.
Bobrovskaya L; Health and Biomedical Innovation, Clinical and Health Sciences, University of South Australia, Adelaide, SA, 5000, Australia.
Zhou XF; Health and Biomedical Innovation, Clinical and Health Sciences, University of South Australia, Adelaide, SA, 5000, Australia. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2021 Dec; Vol. 39 (6), pp. 1689-1707. Date of Electronic Publication: 2021 Oct 02.
Typ publikacji:
Journal Article
MeSH Terms:
Edaravone/*therapeutic use
Frontotemporal Dementia/*drug therapy
Neuroprotective Agents/*therapeutic use
Administration, Oral ; Animals ; Blotting, Western ; Brain/pathology ; Edaravone/administration & dosage ; Female ; Frontotemporal Dementia/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Morris Water Maze Test ; Neuroprotective Agents/administration & dosage ; Open Field Test ; tau Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Quercetin Exhibits α7nAChR/Nrf2/HO-1-Mediated Neuroprotection Against STZ-Induced Mitochondrial Toxicity and Cognitive Impairments in Experimental Rodents.
Autorzy:
Singh NK; Division of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura, 281406, India.
Garabadu D; Division of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura, 281406, India. .; Department of Pharmacology, School of Health Sciences, Central University of Punjab, Bathinda, 151401, India. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2021 Dec; Vol. 39 (6), pp. 1859-1879. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji:
Journal Article
MeSH Terms:
Cognitive Dysfunction/*drug therapy
Heme Oxygenase (Decyclizing)/*metabolism
Mitochondria/*drug effects
NF-E2-Related Factor 2/*metabolism
Neuroprotective Agents/*therapeutic use
Quercetin/*therapeutic use
Streptozocin/*toxicity
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Animals ; Brain/drug effects ; Brain/metabolism ; Brain/pathology ; Cognitive Dysfunction/chemically induced ; Male ; Membrane Potential, Mitochondrial/drug effects ; Morris Water Maze Test/drug effects ; Neuroprotective Agents/pharmacology ; Quercetin/pharmacology ; Rats ; Rats, Wistar ; Streptozocin/antagonists & inhibitors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Role of PKC in Regulating NMDARs in Aluminum-Induced Learning and Memory Impairment in Rats.
Autorzy:
He C; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.; Key Lab of Environmental Hazard & Health of Shanxi Province, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.; Key Lab of Cellular Physiology of Education Ministry, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.; Department of Anatomy, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Ji J; Fenyang College, Shanxi Medical University, Fenyang, 032200, Shanxi, China.
Zhao X; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Lei Y; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Li H; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Hao Y; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Zhang S; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Zhang J; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Liu C; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Nie J; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China. .; Key Lab of Environmental Hazard & Health of Shanxi Province, Shanxi Medical University, Taiyuan, 030001, Shanxi, China. .; Key Lab of Cellular Physiology of Education Ministry, Shanxi Medical University, Taiyuan, 030001, Shanxi, China. .
Niu Q; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, 030001, Shanxi, China. .; Key Lab of Environmental Hazard & Health of Shanxi Province, Shanxi Medical University, Taiyuan, 030001, Shanxi, China. .; Key Lab of Cellular Physiology of Education Ministry, Shanxi Medical University, Taiyuan, 030001, Shanxi, China. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2021 Dec; Vol. 39 (6), pp. 2042-2055. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
Aluminum/*toxicity
Learning/*drug effects
Memory/*drug effects
Protein Kinase C/*metabolism
Receptors, N-Methyl-D-Aspartate/*metabolism
Animals ; Blotting, Western ; Dose-Response Relationship, Drug ; Hippocampus/drug effects ; Hippocampus/metabolism ; Male ; Morris Water Maze Test/drug effects ; Open Field Test/drug effects ; Protein Kinase C/physiology ; Rats ; Rats, Sprague-Dawley ; Real-Time Polymerase Chain Reaction ; Receptors, N-Methyl-D-Aspartate/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Rosinidin Attenuates Lipopolysaccharide-Induced Memory Impairment in Rats: Possible Mechanisms of Action Include Antioxidant and Anti-Inflammatory Effects.
Autorzy:
Alshehri S; Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Imam SS; Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
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Źródło:
Biomolecules [Biomolecules] 2021 Nov 23; Vol. 11 (12). Date of Electronic Publication: 2021 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Anthocyanins/*administration & dosage
Anti-Inflammatory Agents/*administration & dosage
Antioxidants/*administration & dosage
Cognitive Dysfunction/*drug therapy
Lipopolysaccharides/*adverse effects
Acetylcholinesterase/metabolism ; Administration, Oral ; Animals ; Anthocyanins/chemistry ; Anthocyanins/pharmacology ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Brain-Derived Neurotrophic Factor/metabolism ; Cognitive Dysfunction/chemically induced ; Cognitive Dysfunction/metabolism ; Cognitive Dysfunction/physiopathology ; Disease Models, Animal ; GPI-Linked Proteins/metabolism ; Male ; Molecular Structure ; Morris Water Maze Test/drug effects ; Oxidative Stress/drug effects ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Silver Nanoparticles Conjugate Attenuates Highly Active Antiretroviral Therapy-Induced Hippocampal Nissl Substance and Cognitive Deficits in Diabetic Rats.
Autorzy:
Lawal SK; Discipline of Clinical Anatomy, School of Laboratory Medicine & Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban, South Africa.
Olojede SO; Discipline of Clinical Anatomy, School of Laboratory Medicine & Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban, South Africa.
Dare A; Department of Physiology, School of Laboratory Medicine & Medical Sciences, Westville Campus, University of KwaZulu-Natal, Durban, South Africa.
Faborode OS; Department of Physiology, School of Laboratory Medicine & Medical Sciences, Westville Campus, University of KwaZulu-Natal, Durban, South Africa.
Naidu ECS; Discipline of Clinical Anatomy, School of Laboratory Medicine & Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban, South Africa.
Rennie CO; Discipline of Clinical Anatomy, School of Laboratory Medicine & Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Durban, South Africa.
Azu OO; Department of Anatomy, School of Medicine, University of Namibia, Windhoek, Private Bag 13301, Namibia.
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Źródło:
Journal of diabetes research [J Diabetes Res] 2021 Nov 19; Vol. 2021, pp. 2118538. Date of Electronic Publication: 2021 Nov 19 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Metal Nanoparticles*
Behavior, Animal/*drug effects
Cognition/*drug effects
Cognitive Dysfunction/*prevention & control
Diabetes Mellitus, Experimental/*complications
Diabetes Mellitus, Type 2/*complications
Diabetic Neuropathies/*prevention & control
Hippocampus/*drug effects
Nissl Bodies/*drug effects
Silver Compounds/*pharmacology
Animals ; Anti-HIV Agents ; Antiretroviral Therapy, Highly Active/adverse effects ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/physiopathology ; Cognitive Dysfunction/psychology ; Diabetic Neuropathies/etiology ; Diabetic Neuropathies/physiopathology ; Diabetic Neuropathies/psychology ; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination ; Hippocampus/pathology ; Hippocampus/physiopathology ; Locomotion/drug effects ; Male ; Memory/drug effects ; Morris Water Maze Test/drug effects ; Nissl Bodies/pathology ; Rats, Sprague-Dawley ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protective effect of quercetin against the metabolic dysfunction of glucose and lipids and its associated learning and memory impairments in NAFLD rats.
Autorzy:
Gao XR; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, People's Republic of China.; The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei, China.; Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei, China.
Chen Z; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, People's Republic of China.; The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei, China.; Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei, China.
Fang K; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, People's Republic of China.; The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei, China.; Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei, China.
Xu JX; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, People's Republic of China.; The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei, China.; Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei, China.
Ge JF; School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei, 230032, People's Republic of China. .; The Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Medical University, Hefei, China. .; Anhui Provincial Laboratory of Inflammatory and Immune Disease, Anhui Institute of Innovative Drugs, Hefei, China. .
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2021 Nov 17; Vol. 20 (1), pp. 164. Date of Electronic Publication: 2021 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Memory Disorders/*drug therapy
Metabolic Diseases/*drug therapy
Neuroprotective Agents/*therapeutic use
Non-alcoholic Fatty Liver Disease/*drug therapy
Quercetin/*therapeutic use
Animals ; Blotting, Western ; Disease Models, Animal ; Glucose Tolerance Test ; Liver/pathology ; Male ; Membrane Glycoproteins/blood ; Memory Disorders/etiology ; Metabolic Diseases/etiology ; Morris Water Maze Test/drug effects ; Non-alcoholic Fatty Liver Disease/complications ; Open Field Test/drug effects ; Rats ; Rats, Sprague-Dawley ; Receptors, Immunologic/blood ; Triggering Receptor Expressed on Myeloid Cells-1/blood
Czasopismo naukowe
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