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    Tytuł:
    Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
    Autorzy:
    Hossain MA; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.; Department of Neurosurgery and Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Sarin R; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Biogen Inc, Cambridge, Massachusetts, United States of America.
    Donnelly DP; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.
    Miller BC; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Weiss A; Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
    McAlary L; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, Australia.
    Antonyuk SV; Molecular Biophysics Group, Department of Biochemistry & Systems Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.
    Salisbury JP; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Amin J; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.
    Conway JB; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Watson SS; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Winters JN; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Xu Y; Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, United States of America.
    Alam N; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.
    Brahme RR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.
    Shahbazian H; School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America.
    Sivasankar D; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.
    Padmakumar S; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Sattarova A; Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, United States of America.
    Ponmudiyan AC; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Gawde T; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Verrill DE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.
    Yang W; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.
    Kannapadi S; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Plant LD; Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, United States of America.
    Auclair JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.
    Makowski L; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Department of Bioengineering, Northeastern University, Boston, Massachusetts, United States of America.
    Petsko GA; Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Departments of Chemistry and Biochemistry, and Rosenstiel Center for Basic Medical Research, Brandeis University, Waltham, Massachusetts, United States of America.
    Ringe D; Departments of Chemistry and Biochemistry, and Rosenstiel Center for Basic Medical Research, Brandeis University, Waltham, Massachusetts, United States of America.
    Agar NYR; Department of Neurosurgery and Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
    Greenblatt DJ; School of Medicine, Tufts University, Boston, Massachusetts, United States of America.
    Ondrechen MJ; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.
    Chen Y; Biogen Inc, Cambridge, Massachusetts, United States of America.
    Yerbury JJ; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, Australia.
    Manetsch R; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, United States of America.
    Hasnain SS; Molecular Biophysics Group, Department of Biochemistry & Systems Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.
    Brown RH Jr; Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
    Agar JN; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America.; Barnett Institute of Chemical and Biological Analysis, Boston, Massachusetts, United States of America.; Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, United States of America.
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    Źródło:
    PLoS biology [PLoS Biol] 2024 Jan 30; Vol. 22 (1), pp. e3002462. Date of Electronic Publication: 2024 Jan 30 (Print Publication: 2024).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Amyotrophic Lateral Sclerosis*/drug therapy
    Amyotrophic Lateral Sclerosis*/genetics
    Amyotrophic Lateral Sclerosis*/metabolism
    Animals ; Mice ; Cysteine/genetics ; Mutation ; Superoxide Dismutase/genetics ; Superoxide Dismutase/chemistry ; Superoxide Dismutase/metabolism ; Superoxide Dismutase-1/genetics
    SCR Disease Name:
    Amyotrophic lateral sclerosis 1
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Stereoselective Synthesis of β-Glycinamide Ribonucleotide.
    Autorzy:
    Ngu L; Department of Chemistry, Northeastern University, Boston, MA 02115, USA.
    Ray D; Department of Chemistry, Northeastern University, Boston, MA 02115, USA.
    Watson SS; Department of Chemistry, Northeastern University, Boston, MA 02115, USA.
    Beuning PJ; Department of Chemistry, Northeastern University, Boston, MA 02115, USA.
    Ondrechen MJ; Department of Chemistry, Northeastern University, Boston, MA 02115, USA.
    O'Doherty GA; Department of Chemistry, Northeastern University, Boston, MA 02115, USA.
    Pokaż więcej
    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2022 Apr 14; Vol. 27 (8). Date of Electronic Publication: 2022 Apr 14.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Hydroxymethyl and Formyl Transferases*
    Glycine/analogs & derivatives ; Phosphoribosylglycinamide Formyltransferase ; Ribonucleotides
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-5 z 5

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