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Wyświetlanie 1-7 z 7
Tytuł :
Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Autorzy :
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Colombo MV; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Arrigoni C; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Bardinet V; Department of Pediatrics, Division of Oncology and Hematology, Charité Berlin, Berlin, Germany.
Saucier D; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Amatruda JF; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.; Children's Hospital of Los Angeles, Los Angeles, CA, USA.
Cossarizza A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Modena, Italy.
Henssen AG; Department of Pediatrics, Division of Oncology and Hematology, Charité Berlin, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany.; Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), partner site, Berlin, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), partner site, Munich, Germany.
Moretti M; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany. .; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. .; German Cancer Consortium (DKTK), partner site, Munich, Germany. .; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 23; Vol. 11 (1), pp. 6068. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Published Erratum
Tytuł :
A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas.
Autorzy :
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany.
Buecklein VL; Department of Internal Medicine III, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany.
Kampmann E; Department of Internal Medicine III, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany.
Subklewe M; Department of Internal Medicine III, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany.
Noessner E; Institute of Molecular Immunology, Helmholtz Center, Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians University Munich, Thalkirchner Str. 36, 80337, Munich, Germany.
Lindner L; Department of Internal Medicine III, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany.
Issels R; Department of Internal Medicine III, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians University Munich, Thalkirchner Str. 36, 80337, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Altendorf-Hofmann A; Department of General, Visceral and Vascular Surgery, Friedrich-Schiller-University, Jena, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany. .; Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians University Munich, Thalkirchner Str. 36, 80337, Munich, Germany. .; German Cancer Consortium (DKTK), partner site Munich, Munich, Germany. .; German Cancer Research Center (DKFZ), Heidelberg, Germany. .
Knösel T; Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians University Munich, Thalkirchner Str. 36, 80337, Munich, Germany. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Jul; Vol. 69 (7), pp. 1353-1362. Date of Electronic Publication: 2020 Mar 28.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
B7-H1 Antigen/*metabolism
Biomarkers, Tumor/*metabolism
Programmed Cell Death 1 Receptor/*metabolism
Sarcoma/*metabolism
Adolescent ; Adult ; Aged ; Cohort Studies ; Female ; Follow-Up Studies ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Neoplasm Metastasis ; Prognosis ; Sarcoma/classification ; Sarcoma/pathology ; Survival Rate ; Young Adult
Czasopismo naukowe
Tytuł :
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Autorzy :
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Colombo MV; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Arrigoni C; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Bardinet V; Department of Pediatrics, Division of Oncology and Hematology, Charité Berlin, Berlin, Germany.
Saucier D; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Amatruda JF; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.; Children's Hospital of Los Angeles, Los Angeles, CA, USA.
Cossarizza A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Modena, Italy.
Henssen AG; Department of Pediatrics, Division of Oncology and Hematology, Charité Berlin, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany.; Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), partner site, Berlin, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), partner site, Munich, Germany.
Moretti M; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. .; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany. .; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. .; German Cancer Consortium (DKTK), partner site, Munich, Germany. .; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 May 15; Vol. 11 (1), pp. 2423. Date of Electronic Publication: 2020 May 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Oxidative Stress*
Oncogene Proteins, Fusion/*metabolism
Sarcoma, Ewing/*pathology
Adult ; Animals ; Bone Neoplasms/pathology ; Cell Line, Tumor ; Cell Proliferation ; Child ; Chondrocytes/metabolism ; DNA Methylation ; Enhancer Elements, Genetic ; Gene Expression Profiling ; HEK293 Cells ; Humans ; Hydrazines/chemistry ; Mesenchymal Stem Cells/metabolism ; Mice ; Microsatellite Repeats ; Mitochondria/metabolism ; Oligonucleotide Array Sequence Analysis ; Oncogenes ; RNA Interference ; SOXD Transcription Factors/metabolism ; Sarcoma/genetics
Czasopismo naukowe
Tytuł :
Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma.
Autorzy :
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Tolkach Y; Institute of Pathology, University Hospital Bonn, Bonn, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany.; Department of Internal Medicine I (Cardiology), Hospital of the LMU Munich, Munich, Germany.
Strauch K; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.
Stief C; Urologic Clinic und Polyclinic, Clinical Center of the University of Munich, Munich, Germany.
Kristiansen G; Institute of Pathology, University Hospital Bonn, Bonn, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Buchner A; Department of Internal Medicine I (Cardiology), Hospital of the LMU Munich, Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), partner site Munich, Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
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Źródło :
International journal of cancer [Int J Cancer] 2020 Apr 01; Vol. 146 (7), pp. 2036-2046. Date of Electronic Publication: 2019 Nov 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor*
Adenocarcinoma/*genetics
Adenocarcinoma/*mortality
Oncogene Proteins, Fusion/*genetics
Prostatic Neoplasms/*genetics
Prostatic Neoplasms/*mortality
Adenocarcinoma/diagnosis ; Computational Biology ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Male ; Neoplasm Grading ; Neoplasm Metastasis ; Neoplasm Staging ; Prognosis ; Prostatic Neoplasms/diagnosis
Czasopismo naukowe
Tytuł :
High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma.
Autorzy :
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Department of Pediatrics, University Hospital Münster, 48149 Münster, Germany.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Paul T; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Surdez D; INSERM Unit 830 'Genetics and Biology of Cancers', Institut Curie Research Center, 75248 Paris, France.
Delattre O; INSERM Unit 830 'Genetics and Biology of Cancers', Institut Curie Research Center, 75248 Paris, France.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Kasan M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.
Henssen AG; Department of Pediatric Hematology/Oncology/BMT, Charité-University Medicine Berlin, 13353 Berlin, Germany.; Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, 13125 Berlin, Germany.
Özen Ö; Department of Pathology, Başkent University Hospital, 06490 Ankara, Turkey.
Sugita S; Department of Surgical Pathology, Sapporo Medical University, 060-8556 Sapporo, Japan.
Hasegawa T; Department of Surgical Pathology, Sapporo Medical University, 060-8556 Sapporo, Japan.
Kanaseki T; Department of Pathology, Sapporo Medical University, 060-8556 Sapporo, Japan.
Bertram S; Institute of Pathology, University Hospital Essen, 45147 Essen, Germany.
Dirksen U; Pediatrics III, AYA Unit, West German Cancer Centre, University Hospital Essen, 45147 Essen, Germany.; German Cancer Consortium (DKTK), Partner site Essen, 45147 Essen, Germany.
Hartmann W; Division of Translational Oncology, Gerhard-Domagk-Institute for Pathology, University Hospital Münster, 48149 Münster, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; German Cancer Consortium (DKTK), Partner site Munich, 80336 Munich, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, 80337 Munich, Germany.; German Cancer Consortium (DKTK), Partner site Munich, 80336 Munich, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
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Źródło :
Cancers [Cancers (Basel)] 2020 Mar 10; Vol. 12 (3). Date of Electronic Publication: 2020 Mar 10.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients.
Autorzy :
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Ranft A; Department of Pediatrics III, West German Cancer Centre, University Hospital Essen, Essen, Germany.
Jabar S; Department of Pediatrics III, West German Cancer Centre, University Hospital Essen, Essen, Germany.
Zacherl C; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Alba-Rubio R; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Kiran MM; Department of Pathology, Medical Faculty, Ankara Yildirim Beyazit University, Ankara, Turkey.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Jürgens H; Department of Pediatric Hematology and Oncology, University Hospital Münster, Münster, Germany.
Sastre A; Unidad hemato-oncología pediátrica, Hospital Infantil Universitario La Paz, Madrid, Spain.
Alonso J; Pediatric Solid Tumour Laboratory, Institute of Rare Diseases Research (IIER), Instituto de Salud Carlos III, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras, Instituto de Salud Carlos III (CB06/07/1009; CIBERER-ISCIII), Spain.
Da Silveira W; Center for Genomics Medicine, Medical University of South Carolina, Charleston, SC, USA.
Hardiman G; Center for Genomics Medicine, Medical University of South Carolina, Charleston, SC, USA; School of Biological Sciences, Institute for Global Food Security, Queen's University Belfast, Belfast, UK.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Hartmann W; Gerhard-Domagk Institute of Pathology, University Hospital of Münster, Münster, Germany.
Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Germany; German Cancer Consortium (DKTK), partner site Munich, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Dirksen U; Department of Pediatrics III, West German Cancer Centre, University Hospital Essen, Essen, Germany; German Cancer Consortium (DKTK), partner site Essen, Germany. Electronic address: .
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany; German Cancer Consortium (DKTK), partner site Munich, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: .
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Źródło :
EBioMedicine [EBioMedicine] 2019 Sep; Vol. 47, pp. 156-162. Date of Electronic Publication: 2019 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression*
SOXB1 Transcription Factors/*genetics
SOXB1 Transcription Factors/*metabolism
Sarcoma, Ewing/*genetics
Sarcoma, Ewing/*metabolism
Biomarkers ; Biomarkers, Tumor ; Female ; Humans ; Immunohistochemistry ; Male ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Prognosis ; Risk Factors ; Sarcoma, Ewing/diagnosis ; Sarcoma, Ewing/mortality
Czasopismo naukowe
Tytuł :
Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma.
Autorzy :
Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Alba Rubio R; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.; Institute of Pathology of the LMU Munich, Munich, Germany.
Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Wehweck FS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.; Institute of Pathology of the LMU Munich, Munich, Germany.
Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Kirchner T; Institute of Pathology of the LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.
Bach H; Department of Medicine, Division of Infectious Diseases, and IIRC Antibody Engineering and Proteomics facility, University of British Columbia, Vancouver, BC, Canada.
Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany.
Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology of the LMU Munich, Munich, Germany. .; Institute of Pathology of the LMU Munich, Munich, Germany. .; German Cancer Consortium (DKTK), Heidelberg, Germany. .; German Cancer Research Center (DKFZ), Heidelberg, Germany. .
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Źródło :
Cell death & disease [Cell Death Dis] 2019 Feb 11; Vol. 10 (2), pp. 116. Date of Electronic Publication: 2019 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcitonin Gene-Related Peptide/*metabolism
Receptor Activity-Modifying Protein 1/*metabolism
Sarcoma, Ewing/*pathology
Animals ; Calcitonin Gene-Related Peptide/antagonists & inhibitors ; Calcitonin Gene-Related Peptide/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Mice, Inbred NOD ; Microsatellite Repeats/genetics ; RNA Interference ; RNA, Small Interfering/metabolism ; RNA, Small Interfering/therapeutic use ; Receptor Activity-Modifying Protein 1/antagonists & inhibitors ; Receptor Activity-Modifying Protein 1/genetics ; Sarcoma, Ewing/drug therapy ; Sarcoma, Ewing/metabolism ; Small Molecule Libraries/pharmacology ; Transplantation, Heterologous
Czasopismo naukowe
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