- Tytuł:
- A phase I trial of metformin in combination with vincristine, irinotecan, and temozolomide in children with relapsed or refractory solid and central nervous system tumors: A report from the national pediatric cancer foundation.
- Autorzy:
- Źródło:
- Cancer medicine [Cancer Med] 2023 Feb; Vol. 12 (4), pp. 4270-4281. Date of Electronic Publication: 2022 Sep 23.
- Typ publikacji:
- Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Sarcoma, Ewing*/drug therapy
Metformin*/therapeutic use
Neoplasms*/drug therapy
Neoplasms*/etiology
Central Nervous System Neoplasms*/drug therapy
Child ; Humans ; Child, Preschool ; Adolescent ; Irinotecan/adverse effects ; Temozolomide/therapeutic use ; Vincristine/therapeutic use ; Camptothecin ; Dacarbazine ; Maximum Tolerated Dose ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics ; Neoplasm Recurrence, Local/drug therapy
Czasopismo naukowe