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    Wyświetlanie 1-16 z 16
    Tytuł:
    Profile of bevacizumab in the treatment of platinum-resistant ovarian cancer: current perspectives
    Autorzy:
    McClung EC
    Wenham RM
    Pokaż więcej
    Temat:
    Bevacizumab
    angiogenesis
    ovarian cancer
    platinum resistant ovarian cancer
    recurrent ovarian cancer
    Gynecology and obstetrics
    RG1-991
    Źródło:
    International Journal of Women's Health, Vol 2016, Iss Issue 1, Pp 59-75 (2016)
    Opis pliku:
    electronic resource
    Relacje:
    https://www.dovepress.com/profile-of-bevacizumab-in-the-treatment-of-platinum-resistant-ovarian--peer-reviewed-article-IJWH; https://doaj.org/toc/1179-1411
    Dostęp URL:
    https://doaj.org/article/d35612b2a0c84135a4f99d0074c5d815  Link otwiera się w nowym oknie
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes.
    Autorzy:
    Robertson SE; Department of Gynecology Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Yasukawa M; Department of Gynecology Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Marchion DC; Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Xiong Y; Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Naqvi SMH; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Gheit T; International Agency for Research on Cancer, World Health Organization, Lyon, France.
    Tommasino M; International Agency for Research on Cancer, World Health Organization, Lyon, France.
    Wenham RM; Department of Gynecology Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida, United States of America.
    Giuliano AR; Risk Assessment, Detection and Intervention Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Lancaster JM; Department of Gynecology Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida, United States of America.
    Shahzad MMK; Department of Gynecology Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Department of Oncologic Sciences, University of South Florida, Tampa, Florida, United States of America.
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    Źródło:
    PloS one [PLoS One] 2023 Dec 01; Vol. 18 (12), pp. e0294448. Date of Electronic Publication: 2023 Dec 01 (Print Publication: 2023).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Epstein-Barr Virus Infections*
    Ovarian Neoplasms*/epidemiology
    Ovarian Neoplasms*/genetics
    Cystadenocarcinoma, Serous*/pathology
    Humans ; Female ; Infant ; Aged ; Carcinoma, Ovarian Epithelial/epidemiology ; Carcinoma, Ovarian Epithelial/genetics ; DNA, Viral/genetics ; Prevalence ; Herpesvirus 4, Human/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Relationships among Inflammatory Biomarkers and Objectively Assessed Physical Activity and Sleep during and after Chemotherapy for Gynecologic Malignancies.
    Autorzy:
    Tometich DB; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Hoogland AI; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Small BJ; School of Aging Studies, University of South Florida, Tampa, FL 33620, USA.
    Janelsins MC; Department of Surgery and Neuroscience, University of Rochester Medical Center, Rochester, NY 14642, USA.
    Bryant C; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Rodriguez Y; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Gonzalez BD; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Li X; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Bulls HW; Section of Palliative Care and Medical Ethics, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.
    James BW; Morsani College of Medicine, University of South Florida, Tampa, FL 33620, USA.
    Arboleda B; Morsani College of Medicine, University of South Florida, Tampa, FL 33620, USA.
    Colon-Echevarria C; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Townsend MK; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Tworoger SS; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Rodriguez P; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Oswald LB; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Bower JE; Department of Psychology, University of California Los Angeles, Los Angeles, CA 90095, USA.
    Apte SM; Huntsman Cancer Institute, Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT 84112, USA.
    Wenham RM; Department of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Chon HS; Department of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Shahzad MM; Department of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Jim HSL; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
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    Źródło:
    Cancers [Cancers (Basel)] 2023 Jul 30; Vol. 15 (15). Date of Electronic Publication: 2023 Jul 30.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Relationships among Inflammatory Biomarkers and Self-Reported Treatment-Related Symptoms in Patients Treated with Chemotherapy for Gynecologic Cancer: A Controlled Comparison.
    Autorzy:
    Hoogland AI; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Small BJ; School of Aging Studies, University of South Florida, Tampa, FL 33612, USA.
    Oswald LB; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Bryant C; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Rodriguez Y; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Gonzalez BD; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Li X; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Janelsins MC; Department of Surgery and Neuroscience, University of Rochester Medical Center, Rochester, NY 14642, USA.
    Bulls HW; Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
    James BW; Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA.
    Arboleda B; Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA.
    Colon-Echevarria C; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Townsend MK; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Tworoger SS; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Rodriguez PC; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Bower JE; Department of Psychology, University of California Los Angeles, Los Angeles, CA 90095, USA.
    Apte SM; Department of Obstetrics and Gynecology, Huntsman Cancer Institute, Salt Lake City, UT 84132, USA.
    Wenham RM; Department of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Jim HSL; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
    Pokaż więcej
    Źródło:
    Cancers [Cancers (Basel)] 2023 Jun 29; Vol. 15 (13). Date of Electronic Publication: 2023 Jun 29.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Prognostic features of endometrial cancer metastasis to the central nervous system.
    Autorzy:
    Kuznicki ML; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, United States of America.; Department of Obstetrics and Gynecology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States of America.
    Mallen A; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, United States of America.; Department of Obstetrics and Gynecology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States of America.
    Ha K; Department of Obstetrics and Gynecology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States of America.
    McClung EC; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, United States of America.; Department of Obstetrics and Gynecology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States of America.
    Castaneda AV; Department of Gynecologic Oncology, University of Southern California, Los Angeles, CA, United States of America.; Department of Gynecologic Oncology, Ohio State University, Columbus, OH, United States of America.
    Cao B; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States of America.
    Fridley BL; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States of America.
    Chon HS; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, United States of America.
    Chern JY; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, United States of America.
    Hoffman M; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, United States of America.
    Wenham RM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, United States of America.
    Matsuo K; Department of Gynecologic Oncology, University of Southern California, Los Angeles, CA, United States of America.
    Shahzad MMK; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, United States of America.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2022 Aug 26; Vol. 17 (8), pp. e0268794. Date of Electronic Publication: 2022 Aug 26 (Print Publication: 2022).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Central Nervous System Neoplasms*
    Endometrial Neoplasms*
    Neoplasms, Second Primary*
    Central Nervous System ; Female ; Humans ; Prognosis ; Retrospective Studies
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Utilizing digital pathology to quantify stromal caveolin-1 expression in malignant and benign ovarian tumors: Associations with clinicopathological parameters and clinical outcomes.
    Autorzy:
    Saeed-Vafa D; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Marchion DC; Tissue Core-Biospecimen Processing Laboratory, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    McCarthy SM; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Hakam A; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Lopez A; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Wenham RM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Apte SM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Chen DT; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Magliocco AM; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Lancaster JM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Reid BM; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
    Permuth JB; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
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    Źródło:
    PloS one [PLoS One] 2021 Nov 23; Vol. 16 (11), pp. e0256615. Date of Electronic Publication: 2021 Nov 23 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Caveolin 1/*metabolism
    Cystadenocarcinoma, Serous/*metabolism
    Ovarian Neoplasms/*metabolism
    Ovary/*metabolism
    Stromal Cells/*metabolism
    Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Cystadenocarcinoma, Serous/mortality ; Cystadenocarcinoma, Serous/pathology ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Middle Aged ; Neoplasm Staging ; Ovarian Neoplasms/mortality ; Ovarian Neoplasms/pathology ; Ovary/pathology ; Stromal Cells/pathology ; Survival Rate ; Tissue Array Analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Quality of life after pelvic exenteration for gynecologic cancer: Findings from a qualitative study.
    Autorzy:
    Nelson AM; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.; Department of Psychology, University of South Florida, Tampa, FL, USA.
    Albizu-Jacob A; Department of Supportive Care Medicine, Moffitt Cancer Center, Tampa, FL, USA.
    Fenech AL; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.; Department of Supportive Care Medicine, Moffitt Cancer Center, Tampa, FL, USA.
    Chon HS; Department of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL, USA.
    Wenham RM; Department of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL, USA.
    Donovan KA; Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.; Department of Supportive Care Medicine, Moffitt Cancer Center, Tampa, FL, USA.
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    Źródło:
    Psycho-oncology [Psychooncology] 2018 Oct; Vol. 27 (10), pp. 2357-2362. Date of Electronic Publication: 2018 Jul 18.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Quality of Life*
    Genital Neoplasms, Female/*surgery
    Neoplasm Recurrence, Local/*surgery
    Pelvic Exenteration/*psychology
    Adult ; Aged ; Female ; Genital Neoplasms, Female/mortality ; Genital Neoplasms, Female/psychology ; Humans ; Interviews as Topic ; Middle Aged ; Neoplasm Recurrence, Local/mortality ; Palliative Care ; Postoperative Period ; Qualitative Research ; Survival Rate ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Phase I study of oral ridaforolimus in combination with paclitaxel and carboplatin in patients with solid tumor cancers.
    Autorzy:
    Chon HS; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33647, USA.
    Kang S; Division of Gynecologic Cancer Research, Center for Uterine Cancer, National Cancer Center, Ilsan-gu Madu-dong, Goyang, 410-768, Korea.
    Lee JK; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33647, USA.
    Apte SM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33647, USA.
    Shahzad MM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33647, USA.
    Williams-Elson I; Clinical Trials Office, Phase 1 Clinical trials, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33647, USA.
    Wenham RM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33647, USA. Robert.Wenham@moffitt.org.
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    Źródło:
    BMC cancer [BMC Cancer] 2017 Jun 08; Vol. 17 (1), pp. 407. Date of Electronic Publication: 2017 Jun 08.
    Typ publikacji:
    Clinical Trial, Phase I; Journal Article
    MeSH Terms:
    Maximum Tolerated Dose*
    Research Design*
    Antineoplastic Combined Chemotherapy Protocols/*adverse effects
    Carboplatin/*adverse effects
    Neoplasms/*drug therapy
    Paclitaxel/*adverse effects
    Sirolimus/*analogs & derivatives
    Administration, Oral ; Adult ; Aged ; Anemia/chemically induced ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/toxicity ; Carboplatin/therapeutic use ; Carboplatin/toxicity ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Fatigue/chemically induced ; Female ; Humans ; Male ; Middle Aged ; Neutropenia/chemically induced ; Paclitaxel/therapeutic use ; Paclitaxel/toxicity ; Sirolimus/administration & dosage ; Sirolimus/adverse effects ; Sirolimus/therapeutic use ; Sirolimus/toxicity ; Thrombocytopenia/chemically induced
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Sensitivity of ovarian cancer cells to acetaminophen reveals biological pathways that affect patient survival.
    Autorzy:
    Bush SH; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Tollin S; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Marchion DC; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Xiong Y; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Abbasi F; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Ramirez IJ; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Zgheib NB; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Boac B; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Judson PL; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Chon HS; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Wenham RM; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Apte SM; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Cubitt CL; Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Berglund AE; Cancer Informatics Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Havrilesky LJ; Duke University Medical Center, Durham, NC 27710, USA.
    Lancaster JM; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
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    Źródło:
    Molecular and clinical oncology [Mol Clin Oncol] 2016 Mar; Vol. 4 (3), pp. 399-404. Date of Electronic Publication: 2016 Jan 07.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Molecular determinants for lymph node metastasis in clinically early-stage endometrial cancer.
    Autorzy:
    Bou Zgheib N; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Marchion DC; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Bush SH; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Judson PL; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Department of Oncologic Sciences, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Wenham RM; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Department of Oncologic Sciences, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Apte SM; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Department of Oncologic Sciences, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Lancaster JM; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Department of Oncologic Sciences, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Gonzalez-Bosquet J; Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Iowa Hospital and Clinics, Iowa, IA 52242, USA.
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    Źródło:
    Oncology letters [Oncol Lett] 2016 Jan; Vol. 11 (1), pp. 323-329. Date of Electronic Publication: 2015 Nov 06.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours.
    Autorzy:
    Brana I; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
    Berger R; Sheba Medical Center, Ramat Gan, Israel.
    Golan T; Sheba Medical Center, Ramat Gan, Israel.
    Haluska P; Mayo Clinic, Rochester, MN, USA.
    Edenfield J; Greenville Health System - Cancer Institute, Greenville, SC, USA.
    Fiorica J; Sarasota Memorial Hospital, Sarasota, FL, USA.
    Stephenson J; Greenville Health System - Cancer Institute, Greenville, SC, USA.
    Martin LP; Fox Chase Cancer Center, Philadelphia, PA, USA.
    Westin S; University of Texas - MD Anderson Cancer Center, Houston, TX, USA.
    Hanjani P; Abington Memorial Hospital, Abington, PA, USA.
    Jones MB; Merck & Co., Inc., North Wales, PA, USA.
    Almhanna K; H Lee Moffitt Cancer Center, Tampa, FL, USA.
    Wenham RM; H Lee Moffitt Cancer Center, Tampa, FL, USA.
    Sullivan DM; 1] H Lee Moffitt Cancer Center, Tampa, FL, USA [2] M2Gen Tampa, Tampa, FL, USA.
    Dalton WS; M2Gen Tampa, Tampa, FL, USA.
    Gunchenko A; Merck & Co., Inc., North Wales, PA, USA.
    Cheng JD; Merck & Co., Inc., North Wales, PA, USA.
    Siu LL; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
    Gray JE; H Lee Moffitt Cancer Center, Tampa, FL, USA.
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    Źródło:
    British journal of cancer [Br J Cancer] 2014 Nov 11; Vol. 111 (10), pp. 1932-44. Date of Electronic Publication: 2014 Oct 07.
    Typ publikacji:
    Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Monoclonal/*therapeutic use
    Benzene Derivatives/*therapeutic use
    Heterocyclic Compounds, 3-Ring/*therapeutic use
    Neoplasms/*drug therapy
    Propionates/*therapeutic use
    Sirolimus/*analogs & derivatives
    Sulfones/*therapeutic use
    Adult ; Aged ; Aged, 80 and over ; Antibodies, Monoclonal/pharmacokinetics ; Antibodies, Monoclonal, Humanized ; Antineoplastic Combined Chemotherapy Protocols ; Benzene Derivatives/pharmacokinetics ; Biomarkers, Tumor/metabolism ; Clinical Trials, Phase II as Topic ; Clinical Trials, Phase III as Topic ; Cohort Studies ; Female ; Follow-Up Studies ; Heterocyclic Compounds, 3-Ring/pharmacokinetics ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Neoplasms/metabolism ; Neoplasms/pathology ; Prognosis ; Propionates/pharmacokinetics ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Randomized Controlled Trials as Topic ; Receptor, IGF Type 1/antagonists & inhibitors ; Receptors, Notch/antagonists & inhibitors ; Sirolimus/pharmacokinetics ; Sirolimus/therapeutic use ; Sulfones/pharmacokinetics ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; Tissue Distribution
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    In vitro analysis of ovarian cancer response to cisplatin, carboplatin, and paclitaxel identifies common pathways that are also associated with overall patient survival.
    Autorzy:
    Bicaku E; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
    Xiong Y
    Marchion DC
    Chon HS
    Stickles XB
    Chen N
    Judson PL
    Hakam A
    Gonzalez-Bosquet J
    Wenham RM
    Apte SM
    Fulp W
    Cubitt CL
    Chen DT
    Lancaster JM
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    Źródło:
    British journal of cancer [Br J Cancer] 2012 Jun 05; Vol. 106 (12), pp. 1967-75. Date of Electronic Publication: 2012 May 17.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
    Ovarian Neoplasms/*drug therapy
    Ovarian Neoplasms/*metabolism
    Carboplatin/administration & dosage ; Cell Line, Tumor/immunology ; Cisplatin/administration & dosage ; Cyclic AMP Response Element-Binding Protein ; Female ; Humans ; Ovarian Neoplasms/mortality ; Paclitaxel/administration & dosage ; Signal Transduction ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    BCL2 antagonist of cell death kinases, phosphatases, and ovarian cancer sensitivity to cisplatin.
    Autorzy:
    Bansal N; Department of Women's Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
    Marchion DC
    Bicaku E
    Xiong Y
    Chen N
    Stickles XB
    Sawah EA
    Wenham RM
    Apte SM
    Gonzalez-Bosquet J
    Judson PL
    Hakam A
    Lancaster JM
    Pokaż więcej
    Źródło:
    Journal of gynecologic oncology [J Gynecol Oncol] 2012 Jan; Vol. 23 (1), pp. 35-42. Date of Electronic Publication: 2012 Jan 09.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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