Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions.
Autorzy:
Honda GS; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America. Pearce RG; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America. Pham LL; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America. Setzer RW; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America. WetmoreBA; National Exposure Research Laboratory, U.S. EPA, Research Triangle Park, North Carolina, United States of America. Sipes NS; Division of the National Toxicology Program, NIEHS, Research Triangle Park, North Carolina, United States of America. Gilbert J; Cyprotex, Watertown, MA, United States of America. Franz B; Cyprotex, Watertown, MA, United States of America. Thomas RS; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America. Wambaugh JF; National Center for Computational Toxicology, U.S. EPA, Research Triangle Park, North Carolina, United States of America.
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Źródło:
PloS one [PLoS One] 2019 May 28; Vol. 14 (5), pp. e0217564. Date of Electronic Publication: 2019 May 28 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Advancements in Life Cycle Human Exposure and Toxicity Characterization.
Autorzy:
Fantke P; Quantitative Sustainability Assessment Division, Department of Management Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark. Aylward L; National Centre for Environmental Toxicology, University of Queensland, Brisbane, Australia. Bare J; U.S. EPA (Environmental Protection Agency), Cincinnati, Ohio, USA. Chiu WA; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, USA. Dodson R; Silent Spring Institute, Newton, Massachusetts, USA. Dwyer R; International Copper Association, New York, New York, USA. Ernstoff A; Quantis, Lausanne, Switzerland. Howard B; American Chemical Council, Washington, DC, USA. Jantunen M; Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland. Jolliet O; School of Public Health, University of Michigan, Ann Arbor, Michigan, USA. Judson R; U.S. EPA, Research Triangle Park, North Carolina, USA. Kirchhübel N; Quantitative Sustainability Assessment Division, Department of Management Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark. Li D; School of Community Health Sciences, University of Nevada, Reno, Nevada, USA. Miller A; National Institute of Environmental Health Sciences, Bethesda, Maryland, USA. Paoli G; Risk Sciences International, Ottawa, Ontario, Canada. Price P; U.S. EPA, Research Triangle Park, North Carolina, USA. Rhomberg L; Gradient, Cambridge, Massachusetts, USA. Shen B; School of Public Health, University of California, Berkeley, California, USA. Shin HM; University of Texas at Arlington, Arlington, Texas, USA. Teeguarden J; Health Effects and Exposure Science, Pacific Northwest National Laboratory, Richland, Washington, USA. Vallero D; U.S. EPA, Research Triangle Park, North Carolina, USA. Wambaugh J; U.S. EPA, Research Triangle Park, North Carolina, USA. WetmoreBA; U.S. EPA, Research Triangle Park, North Carolina, USA. Zaleski R; ExxonMobil Biomedical Sciences, Inc., Annandale, New Jersey, USA. McKone TE; School of Public Health, University of California, Berkeley, California, USA.
Evaluation and Optimization of Pharmacokinetic Models for in Vitro to in Vivo Extrapolation of Estrogenic Activity for Environmental Chemicals.
Autorzy:
Casey WM; National Toxicology Program Division, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA. Chang X; Integrated Laboratory Systems, Inc., Morrisville, North Carolina, USA. Allen DG; Integrated Laboratory Systems, Inc., Morrisville, North Carolina, USA. Ceger PC; Integrated Laboratory Systems, Inc., Morrisville, North Carolina, USA. Choksi NY; Integrated Laboratory Systems, Inc., Morrisville, North Carolina, USA. Hsieh JH; Kelly Government Solutions, Research Triangle Park, North Carolina, USA. WetmoreBA; ScitoVation, Research Triangle Park, North Carolina, USA. Ferguson SS; National Toxicology Program Division, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA. DeVito MJ; National Toxicology Program Division, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA. Sprankle CS; Integrated Laboratory Systems, Inc., Morrisville, North Carolina, USA. Kleinstreuer NC; National Toxicology Program Division, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.
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