High-Throughput Screening for the Prevalence of Neutralizing Antibodies against Human Adenovirus Serotype 5.
Autorzy:
WettengelJM; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.; Institute of Virology, Technical University of Munich, 81675 Munich, Germany.; German Center for Infection Research, Munich Partner Site, 81675 Munich, Germany. Naka H; Division of Genetics, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Dissen GA; Molecular Virology Core, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Torgerson J; Molecular Virology Core, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Pounder M; Molecular Virology Core, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Mueller SF; LABOKLIN GmbH, 97688 Bad Kissingen, Germany. Mueller E; LABOKLIN GmbH, 97688 Bad Kissingen, Germany. Hagen P; Institute of Virology, Technical University of Munich, 81675 Munich, Germany. Brandt M; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Protzer U; Institute of Virology, Technical University of Munich, 81675 Munich, Germany.; German Center for Infection Research, Munich Partner Site, 81675 Munich, Germany. Burwitz BJ; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
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Vaccines [Vaccines (Basel)] 2024 Feb 01; Vol. 12 (2). Date of Electronic Publication: 2024 Feb 01.
Improved detection of infection with SARS-CoV-2 Omicron variants of concern in healthcare workers by a second-generation rapid antigen test.
Autorzy:
WettengelJM; Institute of Virology, School of Medicine and Health, Technical University of Munich (TUM) , München, Germany.; German Center for Infection Research (DZIF), Munich Partner Site , München, Germany. Strehle K; Institute of Molecular Immunology, School of Medicine and Health, TUM , München, Germany.; Coronavirus Diagnostic Center of the University Hospital München Rechts der Isar, School of Medicine, TUM , München, Germany. von Lucke C; Coronavirus Diagnostic Center of the University Hospital München Rechts der Isar, School of Medicine, TUM , München, Germany. Roggendorf H; Institute of Molecular Immunology, School of Medicine and Health, TUM , München, Germany.; Coronavirus Diagnostic Center of the University Hospital München Rechts der Isar, School of Medicine, TUM , München, Germany. Jeske SD; Institute of Virology, School of Medicine and Health, Technical University of Munich (TUM) , München, Germany. Christa C; Institute of Virology, School of Medicine and Health, Technical University of Munich (TUM) , München, Germany. Zelger O; Coronavirus Diagnostic Center of the University Hospital München Rechts der Isar, School of Medicine, TUM , München, Germany. Haller B; Institute for AI and Informatics in Medicine Statistics, School of Medicine and Health, TUM , München, Germany. Protzer U; Institute of Virology, School of Medicine and Health, Technical University of Munich (TUM) , München, Germany.; German Center for Infection Research (DZIF), Munich Partner Site , München, Germany.; Institute of Virology, Helmholtz Munich , München, Germany. Knolle PA; German Center for Infection Research (DZIF), Munich Partner Site , München, Germany.; Institute of Molecular Immunology, School of Medicine and Health, TUM , München, Germany.
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Microbiology spectrum [Microbiol Spectr] 2023 Dec 12; Vol. 11 (6), pp. e0176823. Date of Electronic Publication: 2023 Oct 13.
Implementation and clinical evaluation of an Mpox virus laboratory-developed test on a fully automated random-access platform.
Autorzy:
WettengelJM; School of Medicine, Institute of Virology, Technical University of Munich, Munich, Germany.; Helmholtz Munich, School of Medicine, Institute of Virology, Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany. Bunse T; School of Medicine, Institute of Virology, Technical University of Munich, Munich, Germany.; Helmholtz Munich, School of Medicine, Institute of Virology, Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany. Jeske SD; School of Medicine, Institute of Virology, Technical University of Munich, Munich, Germany. Wölfel R; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany.; Bundeswehr, Institute of Microbiology, Munich, Germany. Zange S; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany.; Bundeswehr, Institute of Microbiology, Munich, Germany. Taeubner J; QIAGEN GmbH, Strategic Lab Consultancy, Hilden, Germany. Goelnitz U; QIAGEN GmbH, Strategic Lab Consultancy, Hilden, Germany. Protzer U; School of Medicine, Institute of Virology, Technical University of Munich, Munich, Germany.; Helmholtz Munich, School of Medicine, Institute of Virology, Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany.
A Multifunctional and Highly Adaptable Reporter System for CRISPR/Cas Editing.
Autorzy:
WettengelJM; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA.; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, 81675 München, Germany. Hansen-Palmus L; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, 81675 München, Germany. Yusova S; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA. Rust L; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA. Biswas S; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA. Carson J; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA. Ryu J; Division of Reproductive & Developmental, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Bimber BN; Division of Genetics, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Hennebold JD; Division of Reproductive & Developmental, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.; Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR 97239, USA. Burwitz BJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Hepatitis B Virus Targets Lipid Transport Pathways to Infect Hepatocytes.
Autorzy:
Esser K; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany. Electronic address: . Cheng X; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany. WettengelJM; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany. Lucifora J; INSERM U1052, CNRS UMR-5286, Cancer Research Center of Lyon (CRCL), Lyon, and University of Lyon, Université Claude-Bernard (UCBL), Lyon, France; CIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, University of Lyon, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS Lyon, France. Hansen-Palmus L; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany. Austen K; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany. Roca Suarez AA; CIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, University of Lyon, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS Lyon, France. Heintz S; CIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, University of Lyon, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS Lyon, France. Testoni B; CIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, University of Lyon, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS Lyon, France. Nebioglu F; Heidelberg University, Medical Faculty Heidelberg, Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Diseases Research, Heidelberg, Germany. Pham MT; Heidelberg University, Medical Faculty Heidelberg, Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Diseases Research, Heidelberg, Germany. Yang S; Heidelberg University, Medical Faculty Heidelberg, Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Diseases Research, Heidelberg, Germany. Zernecke A; Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany. Wohlleber D; Institute of Molecular Immunology and Experimental Oncology, University Hospital rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany; German Center for Infection Research (DZIF), Munich and Heidelberg partner sites, Munich and Heidelberg, Germany. Ringelhan M; German Center for Infection Research (DZIF), Munich and Heidelberg partner sites, Munich and Heidelberg, Germany; 2nd Medical Department, University Hospital rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany. Broxtermann M; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany. Hartmann D; Department of Surgery, University Hospital rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany. Hüser N; Department of Surgery, University Hospital rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany. Mergner J; Bavarian Center for Biomolecular Mass Spectrometry at Klinikum rechts der Isar (BayBioMS@MRI), TUM, Munich, Germany. Pichlmair A; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany; German Center for Infection Research (DZIF), Munich and Heidelberg partner sites, Munich and Heidelberg, Germany; Bavarian Center for Biomolecular Mass Spectrometry at Klinikum rechts der Isar (BayBioMS@MRI), TUM, Munich, Germany. Thasler WE; Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Grosshadern Hospital, Ludwig Maximilians University, Munich, Germany. Heikenwalder M; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany. Gasteiger G; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany. Blutke A; Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany. Walch A; Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany. Knolle PA; Institute of Molecular Immunology and Experimental Oncology, University Hospital rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany; German Center for Infection Research (DZIF), Munich and Heidelberg partner sites, Munich and Heidelberg, Germany. Bartenschlager R; Heidelberg University, Medical Faculty Heidelberg, Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Diseases Research, Heidelberg, Germany; German Center for Infection Research (DZIF), Munich and Heidelberg partner sites, Munich and Heidelberg, Germany; Division Virus-Associated Carcinogenesis, German Cancer Research Center (DKFZ), Heidelberg, Germany. Protzer U; Institute of Virology, Technical University of Munich, School of Medicine / Helmholtz Munich, Munich, Germany; German Center for Infection Research (DZIF), Munich and Heidelberg partner sites, Munich and Heidelberg, Germany. Electronic address: .
Mitosis of hepatitis B virus-infected cells in vitro results in uninfected daughter cells.
Autorzy:
Tu T; Storr Liver Centre, Westmead Clinical School and Westmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.; Sydney Institute for Infectious Diseases, University of Sydney at Westmead Hospital, Westmead, NSW, Australia. Zehnder B; Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany. WettengelJM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany. Zhang H; Storr Liver Centre, Westmead Clinical School and Westmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia. Coulter S; Storr Liver Centre, Westmead Clinical School and Westmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia. Ho V; Storr Liver Centre, Westmead Clinical School and Westmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia. Douglas MW; Storr Liver Centre, Westmead Clinical School and Westmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.; Sydney Institute for Infectious Diseases, University of Sydney at Westmead Hospital, Westmead, NSW, Australia. Protzer U; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany. George J; Storr Liver Centre, Westmead Clinical School and Westmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia. Urban S; Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany.; German Center for Infection Research (DZIF), Heidelberg Partner Site, Heidelberg, Germany.
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JHEP reports : innovation in hepatology [JHEP Rep] 2022 Jun 15; Vol. 4 (9), pp. 100514. Date of Electronic Publication: 2022 Jun 15 (Print Publication: 2022).
Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity.
Autorzy:
Biswas S; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, 97006, USA. Rust LN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, 97006, USA. WettengelJM; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, 97006, USA.; Institute of Virology, Technical University of Munich / Helmholtz Zentrum München, München, 81675, Germany. Yusova S; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, 97006, USA. Fischer M; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, 97006, USA. Carson JN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, 97006, USA. Johnson J; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, 97006, USA. Wei L; Department of Molecular Biology, Princeton University, Princeton, NJ, 08544, USA. Thode T; Translational Genomics Research Institute, Phoenix, AZ, 85004, USA. Kaadige MR; Translational Genomics Research Institute, Phoenix, AZ, 85004, USA. Sharma S; Translational Genomics Research Institute, Phoenix, AZ, 85004, USA. Agbaria M; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 12272, Israel. Bimber BN; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, 97006, USA. Tu T; Storr Liver Centre, Westmead Clinical School and Westmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, 2145, Australia.; Centre for Infectious Diseases and Microbiology, Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney at Westmead Hospital, Westmead, NSW, 2145, Australia. Protzer U; Institute of Virology, Technical University of Munich / Helmholtz Zentrum München, München, 81675, Germany. Ploss A; Department of Molecular Biology, Princeton University, Princeton, NJ, 08544, USA. Smedley JV; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, 97006, USA. Golomb G; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 12272, Israel. Sacha JB; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, 97006, USA.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, 97006, USA. Burwitz BJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, 97006, USA. .; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, 97006, USA. .
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Nature communications [Nat Commun] 2022 May 30; Vol. 13 (1), pp. 2995. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Rapid, accurate mapping of transgene integration in viable rhesus macaque embryos using enhanced-specificity tagmentation-assisted PCR.
Autorzy:
Ryu J; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Chan W; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. WettengelJM; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, München, 81675 Germany.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA. Hanna CB; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Burwitz BJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA.; Division of Pathobiology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA. Hennebold JD; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.; Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR 97239, USA. Bimber BN; Division of Pathobiology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.; Division of Genetics, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
T-cell engager antibodies enable T cells to control HBV infection and to target HBsAg-positive hepatoma in mice.
Autorzy:
Quitt O; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Luo S; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Meyer M; Antigen Presentation and T/NK Cell Activation Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Centre, Heidelberg, Germany. Xie Z; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Golsaz-Shirazi F; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Loffredo-Verde E; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Festag J; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Bockmann JH; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich and Hamburg Partner sites, Germany; Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Zhao L; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Stadler D; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Chou WM; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Tedjokusumo R; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. WettengelJM; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Ko C; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Noeßner E; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Bulbuc N; Antigen Presentation and T/NK Cell Activation Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Centre, Heidelberg, Germany. Shokri F; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Lüttgau S; Department of Translational Immunology, German Cancer Research Centre, Heidelberg, Germany. Heikenwälder M; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Bohne F; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany. Moldenhauer G; Department of Translational Immunology, German Cancer Research Centre, Heidelberg, Germany. Momburg F; Antigen Presentation and T/NK Cell Activation Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Centre, Heidelberg, Germany. Protzer U; Institute of Virology, School of Medicine, Technical University of Munich, Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich and Hamburg Partner sites, Germany. Electronic address: .
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Journal of hepatology [J Hepatol] 2021 Nov; Vol. 75 (5), pp. 1058-1071. Date of Electronic Publication: 2021 Jun 23.
Concentration of Na -taurocholate-cotransporting polypeptide expressed after in vitro-transcribed mRNA transfection determines susceptibility of hepatoma cells for hepatitis B virus.
Autorzy:
Oswald A; Institute of Virology, School of Medicine, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany. Chakraborty A; Institute of Virology, School of Medicine, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany. Ni Y; Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Heidelberg, Heidelberg, Germany. WettengelJM; Institute of Virology, School of Medicine, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany. Urban S; Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Heidelberg, Heidelberg, Germany. Protzer U; Institute of Virology, School of Medicine, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany. .; German Center for Infection Research (DZIF), partner site Munich, Munich, Germany. .
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Scientific reports [Sci Rep] 2021 Oct 05; Vol. 11 (1), pp. 19799. Date of Electronic Publication: 2021 Oct 05.
Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP.
Autorzy:
Appelman MD; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands. WettengelJM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. Protzer U; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany. Oude Elferink RPJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Rapid and Robust Continuous Purification of High-Titer Hepatitis B Virus for In Vitro and In Vivo Applications.
Autorzy:
WettengelJM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, 81675 Munich, Germany.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA. Linden B; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, 81675 Munich, Germany. Esser K; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, 81675 Munich, Germany. Laue M; Advanced Light and Electron Microscopy (ZBS 4), Robert Koch Institute, 13353 Berlin, Germany. Burwitz BJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA. Protzer U; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, 81675 Munich, Germany.
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Viruses [Viruses] 2021 Jul 30; Vol. 13 (8). Date of Electronic Publication: 2021 Jul 30.
Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter.
Autorzy:
Wing PAC; Nuffield Department of Medicine, University of Oxford, Oxford, UK; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. Liu PJ; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Harris JM; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Magri A; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Michler T; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany. Zhuang X; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Borrmann H; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Minisini R; Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy. Frampton NR; Institute of Inflammation and Immunotherapy, University of Birmingham, Birmingham, UK. WettengelJM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany. Mailly L; Université de Strasbourg, Strasbourg, France; INSERM, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France. D'Arienzo V; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Riedl T; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. Nobre L; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. Weekes MP; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. Pirisi M; Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy. Heikenwalder M; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. Baumert TF; Université de Strasbourg, Strasbourg, France; INSERM, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France. Hammond EM; Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK. Mole DR; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Protzer U; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany. Balfe P; Nuffield Department of Medicine, University of Oxford, Oxford, UK. McKeating JA; Nuffield Department of Medicine, University of Oxford, Oxford, UK; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. Electronic address: .
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Journal of hepatology [J Hepatol] 2021 Jul; Vol. 75 (1), pp. 64-73. Date of Electronic Publication: 2021 Jan 29.
Prolonged norovirus infections correlate to quasispecies evolution resulting in structural changes of surface-exposed epitopes.
Autorzy:
Afridi SQ; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany. Usman Z; Department of Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universität München, 85354 Freising, Germany. Donakonda S; Institute of Molecular Immunology and Experimental Oncology, Technische Universität München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany. WettengelJM; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany. Velkov S; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany. Beck R; Institute of Medical Virology and Epidemiology of Viral diseases, Universitäts Klinikum Tübingen, 72076 Tübingen, Germany. Gerhard M; Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany. Knolle P; Institute of Molecular Immunology and Experimental Oncology, Technische Universität München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany. Frishman D; Department of Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universität München, 85354 Freising, Germany. Protzer U; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany. Moeini H; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany. Hoffmann D; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany.
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IScience [iScience] 2021 Jun 30; Vol. 24 (7), pp. 102802. Date of Electronic Publication: 2021 Jun 30 (Print Publication: 2021).
Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.
Autorzy:
Stadler D; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Kächele M; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Jones AN; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.; Center for Integrated Protein Science Munich and Bavarian NMR Center at Department of Chemistry, Technical University of Munich, Garching, Germany. Hess J; Research Unit Radiation Cytogenetics, Helmholtz Zentrum München, Neuherberg, Germany.; Department of Radiation Oncology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.; Clinical Cooperation Group Personalized Radiotherapy in Head and Neck Cancer, Helmholtz Zentrum München, Neuherberg, Germany. Urban C; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Schneider J; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Xia Y; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany.; State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China. Oswald A; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Nebioglu F; Department of Infectious Diseases, Molecular Virology, University of Heidelberg, Heidelberg, Germany. Bester R; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Lasitschka F; Institute of Pathology (DZIF tissue bank), University of Heidelberg, Heidelberg, Germany. Ringelhan M; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany.; Department of Internal Medicine II, University Hospital rechts der Isar, Technical University of Munich, Munich, Germany. Ko C; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Chou WM; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Geerlof A; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.; Center for Integrated Protein Science Munich and Bavarian NMR Center at Department of Chemistry, Technical University of Munich, Garching, Germany. van de Klundert MA; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. WettengelJM; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Schirmacher P; Institute of Pathology (DZIF tissue bank), University of Heidelberg, Heidelberg, Germany.; German Center for Infection Research (DZIF), Heidelberg, Germany. Heikenwälder M; German Center for Infection Research (DZIF), Heidelberg, Germany.; Division Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. Schreiner S; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany. Bartenschlager R; Department of Infectious Diseases, Molecular Virology, University of Heidelberg, Heidelberg, Germany.; German Center for Infection Research (DZIF), Heidelberg, Germany.; Division Virus-Associated Carcinogenesis, German Cancer Research Center (DKFZ), Heidelberg, Germany. Pichlmair A; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany.; German Center for Infection Research (DZIF), Heidelberg, Germany. Sattler M; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.; Center for Integrated Protein Science Munich and Bavarian NMR Center at Department of Chemistry, Technical University of Munich, Garching, Germany. Unger K; Research Unit Radiation Cytogenetics, Helmholtz Zentrum München, Neuherberg, Germany.; Department of Radiation Oncology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.; Clinical Cooperation Group Personalized Radiotherapy in Head and Neck Cancer, Helmholtz Zentrum München, Neuherberg, Germany. Protzer U; Institute of Virology, School of Medicine, Technical University of Munich / Helmholtz Zentrum München, Munich, Germany.; German Center for Infection Research (DZIF), Heidelberg, Germany.
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EMBO reports [EMBO Rep] 2021 Jun 04; Vol. 22 (6), pp. e49568. Date of Electronic Publication: 2021 May 09.
Evaluation of two rapid antigen tests to detect SARS-CoV-2 in a hospital setting.
Autorzy:
Osterman A; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany. Baldauf HM; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany. Eletreby M; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany. WettengelJM; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany. Afridi SQ; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany. Fuchs T; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany. Holzmann E; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany. Maier A; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany. Döring J; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany. Grzimek-Koschewa N; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany. Muenchhoff M; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany. Protzer U; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany.; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany. Kaderali L; Institute of Bioinformatics, University Medicine Greifswald, Greifswald, Germany. Keppler OT; Max von Pettenkofer Institute and Gene Center, Virology, National Reference Center for Retroviruses, LMU München, Pettenkoferstr. 9a, 80336, Munich, Germany. .; German Center for Infection Research (DZIF), Partner Site Munich, Munich, Germany. .
Synchronised infection identifies early rate-limiting steps in the hepatitis B virus life cycle.
Autorzy:
Chakraborty A; Institute of Virology, Technical University of Munich, School of Medicine/Helmholtz Zentrum München, Munich, Germany.; Technical University of Munich, Institute for Advanced Study, Munich, Germany. Ko C; Institute of Virology, Technical University of Munich, School of Medicine/Helmholtz Zentrum München, Munich, Germany. Henning C; Institute of Virology, Technical University of Munich, School of Medicine/Helmholtz Zentrum München, Munich, Germany. Lucko A; Institute of Virology, Technical University of Munich, School of Medicine/Helmholtz Zentrum München, Munich, Germany. Harris JM; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Chen F; Institute of Virology, Technical University of Munich, School of Medicine/Helmholtz Zentrum München, Munich, Germany. Zhuang X; Nuffield Department of Medicine, University of Oxford, Oxford, UK. WettengelJM; Institute of Virology, Technical University of Munich, School of Medicine/Helmholtz Zentrum München, Munich, Germany. Roessler S; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. Protzer U; Institute of Virology, Technical University of Munich, School of Medicine/Helmholtz Zentrum München, Munich, Germany.; Technical University of Munich, Institute for Advanced Study, Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany. McKeating JA; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
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Cellular microbiology [Cell Microbiol] 2020 Dec; Vol. 22 (12), pp. e13250. Date of Electronic Publication: 2020 Sep 28.
Innovative HBV Animal Models Based on the Entry Receptor NTCP.
Autorzy:
WettengelJM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, 505 N.W. 185th Avenue Beaverton, Tanasbourne, OR 97006, USA. Burwitz BJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, 505 N.W. 185th Avenue Beaverton, Tanasbourne, OR 97006, USA.
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Źródło:
Viruses [Viruses] 2020 Jul 30; Vol. 12 (8). Date of Electronic Publication: 2020 Jul 30.
Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients.
Autorzy:
Afridi SQ; Institute of Virology, Technische Universität und Helmholtz Zentrum München, Munich, Germany. Moeini H; Institute of Virology, Technische Universität und Helmholtz Zentrum München, Munich, Germany. Kalali B; Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany. WettengelJM; Institute of Virology, Technische Universität und Helmholtz Zentrum München, Munich, Germany. Quitt O; Institute of Virology, Technische Universität und Helmholtz Zentrum München, Munich, Germany. Semper R; Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany. Gerhard M; Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany. Protzer U; Institute of Virology, Technische Universität und Helmholtz Zentrum München, Munich, Germany. Hoffmann D; Institute of Virology, Technische Universität und Helmholtz Zentrum München, Munich, Germany. .
Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels.
Autorzy:
Ko C; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. Chakraborty A; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; Technische Universität München, Institute for Advanced Study, Munich, Germany. Chou WM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. Hasreiter J; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. WettengelJM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. Stadler D; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. Bester R; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. Asen T; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. Zhang K; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. Wisskirchen K; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany. McKeating JA; Technische Universität München, Institute for Advanced Study, Munich, Germany; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom. Ryu WS; Department of Biochemistry, Yonsei University, Seoul, Republic of Korea. Protzer U; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; Technische Universität München, Institute for Advanced Study, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany. Electronic address: .
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Źródło:
Journal of hepatology [J Hepatol] 2018 Dec; Vol. 69 (6), pp. 1231-1241. Date of Electronic Publication: 2018 Aug 22.
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