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    Wyświetlanie 1-18 z 18
    Tytuł:
    Three-year clinical outcome with the Endeavor™ zotarolimus-eluting stent in primary percutaneous coronary intervention for ST elevation myocardial infarction: the Endeavor™ primary PCI study (E-PPCI).
    Autorzy:
    Shelton RJ
    Chitkara K
    Singh R
    Dorsch MF
    Somers K
    McLenachan JM
    Blaxill JM
    Wheatcroft SB
    Blackman DJ
    Greenwood JP
    Shelton, Rhidian J
    Chitkara, Kamal
    Singh, Ravi
    Dorsch, Micha F
    Somers, Kathryn
    McLenachan, James M
    Blaxill, Jonathan M
    Wheatcroft, Stephen B
    Blackman, Daniel J
    Greenwood, John P
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    Źródło:
    Journal of Interventional Cardiology; Dec2011, Vol. 24 Issue 6, p542-548, 7p
    Czasopismo naukowe
    Szczegóły
    Tytuł:
    Coronary Guidewires in Temporary Cardiac Pacing and Assessment of Myocardial Viability: Current Perspectives and Future Directions.
    Autorzy:
    Javid R; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK.; Leeds General Infirmary, Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds LS1 3EX, UK.
    Wassef N; Leeds General Infirmary, Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds LS1 3EX, UK.
    Wheatcroft SB; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK.; Leeds General Infirmary, Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds LS1 3EX, UK.
    Tayebjee MH; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds LS2 9JT, UK.; Leeds General Infirmary, Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds LS1 3EX, UK.
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    Źródło:
    Journal of clinical medicine [J Clin Med] 2023 Nov 08; Vol. 12 (22). Date of Electronic Publication: 2023 Nov 08.
    Typ publikacji:
    Journal Article; Review
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Transcoronary electrophysiological parameters in patients undergoing elective and acute coronary intervention.
    Autorzy:
    Javid R; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds, United Kingdom.
    Slater TA; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds, United Kingdom.
    Bowes R; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
    Veerasamy M; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
    Wassef N; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
    Rossington JA; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
    Mozid AM; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
    Kidambi A; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
    Wheatcroft SB; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds, United Kingdom.
    Tayebjee MH; Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds, United Kingdom.
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    Źródło:
    PloS one [PLoS One] 2023 Feb 06; Vol. 18 (2), pp. e0281374. Date of Electronic Publication: 2023 Feb 06 (Print Publication: 2023).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Myocardial Infarction*/therapy
    Coronary Artery Disease*/therapy
    Percutaneous Coronary Intervention*
    Humans ; Contrast Media ; Gadolinium ; Myocardium ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Fractional Flow Reserve versus Angiography-Guided Management of Coronary Artery Disease: A Meta-Analysis of Contemporary Randomised Controlled Trials.
    Autorzy:
    Maznyczka AM; Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.
    Matthews CJ; Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.
    Blaxill JM; Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS1 3EX, UK.
    Greenwood JP; Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS1 3EX, UK.
    Mozid AM; Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS1 3EX, UK.
    Rossington JA; Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS1 3EX, UK.
    Veerasamy M; Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS1 3EX, UK.
    Wheatcroft SB; Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS1 3EX, UK.
    Curzen N; Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK.; Coronary Research Group, University Hospital Southampton NHS Trust, Southampton SO17 1BJ, UK.
    Bulluck H; Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS1 3EX, UK.
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    Źródło:
    Journal of clinical medicine [J Clin Med] 2022 Nov 30; Vol. 11 (23). Date of Electronic Publication: 2022 Nov 30.
    Typ publikacji:
    Journal Article; Review
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    TRPC5 ion channel permeation promotes weight gain in hypercholesterolaemic mice.
    Autorzy:
    Rode B; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK.
    Yuldasheva NY; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK.
    Baxter PD; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK.
    Sedo A; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK.
    Ainscough JF; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK.
    Shires M; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK.
    Kearney MT; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK.
    Bailey MA; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK.
    Wheatcroft SB; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK.
    Beech DJ; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Jan 28; Vol. 9 (1), pp. 773. Date of Electronic Publication: 2019 Jan 28.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Diet, Western/*adverse effects
    Hypercholesterolemia/*genetics
    TRPC Cation Channels/*genetics
    Weight Gain/*genetics
    Animals ; Disease Models, Animal ; Gene Expression Profiling ; Gene Expression Regulation ; Genes, Dominant ; Genetic Markers ; Male ; Mice ; Mice, Knockout, ApoE ; Mice, Transgenic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8.
    Autorzy:
    Smith GA; Endothelial Cell Biology Unit, School of Molecular & Cellular Biology, University of Leeds, LS2 9JT, Leeds, UK.
    Fearnley GW; Endothelial Cell Biology Unit, School of Molecular & Cellular Biology, University of Leeds, LS2 9JT, Leeds, UK.
    Abdul-Zani I; Endothelial Cell Biology Unit, School of Molecular & Cellular Biology, University of Leeds, LS2 9JT, Leeds, UK.
    Wheatcroft SB; Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, LS2 9JT, Leeds, UK.
    Tomlinson DC; Biomedical Health Research Centre & Astbury Centre for Structural Molecular Biology, University of Leeds, LS2 9JT, Leeds, UK.
    Harrison MA; School of Biomedical Sciences, University of Leeds, LS2 9JT, Leeds, UK.
    Ponnambalam S; Endothelial Cell Biology Unit, School of Molecular & Cellular Biology, University of Leeds, LS2 9JT, Leeds, UK.
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    Źródło:
    Traffic (Copenhagen, Denmark) [Traffic] 2016 Jan; Vol. 17 (1), pp. 53-65. Date of Electronic Publication: 2015 Dec 02.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Proteolysis*
    Signal Transduction*
    Endopeptidases/*metabolism
    Endosomal Sorting Complexes Required for Transport/*metabolism
    Ubiquitin Thiolesterase/*metabolism
    Vascular Endothelial Growth Factor Receptor-2/*metabolism
    Endosomes/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Protein Transport ; Ubiquitination
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Scavenger receptor structure and function in health and disease.
    Autorzy:
    Zani IA; Endothelial Cell Biology Unit, School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, UK.
    Stephen SL; Endothelial Cell Biology Unit, School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, UK.
    Mughal NA; Endothelial Cell Biology Unit, School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, UK.; Leeds Vascular Institute, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
    Russell D; Leeds Vascular Institute, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
    Homer-Vanniasinkam S; Leeds Vascular Institute, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
    Wheatcroft SB; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK.
    Ponnambalam S; Endothelial Cell Biology Unit, School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, UK. .
    Pokaż więcej
    Źródło:
    Cells [Cells] 2015 May 22; Vol. 4 (2), pp. 178-201. Date of Electronic Publication: 2015 May 22.
    Typ publikacji:
    Journal Article; Review
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    In silico design and biological evaluation of a dual specificity kinase inhibitor targeting cell cycle progression and angiogenesis.
    Autorzy:
    Latham AM; Endothelial Cell Biology Unit, School of Molecular & Cellular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.
    Kankanala J; School of Chemistry, University of Leeds, Leeds, LS2 9JT, United Kingdom.
    Fearnley GW; Endothelial Cell Biology Unit, School of Molecular & Cellular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.
    Gage MC; Leeds Institute of Cardiovascular & Metabolic Medicine, Faculty of Medicine & Health, University of Leeds, Leeds LS2 9JT, United Kingdom.
    Kearney MT; Leeds Institute of Cardiovascular & Metabolic Medicine, Faculty of Medicine & Health, University of Leeds, Leeds LS2 9JT, United Kingdom.
    Homer-Vanniasinkam S; Leeds Institute of Cardiovascular & Metabolic Medicine, Faculty of Medicine & Health, University of Leeds, Leeds LS2 9JT, United Kingdom.
    Wheatcroft SB; Leeds Institute of Cardiovascular & Metabolic Medicine, Faculty of Medicine & Health, University of Leeds, Leeds LS2 9JT, United Kingdom.
    Fishwick CW; School of Chemistry, University of Leeds, Leeds, LS2 9JT, United Kingdom.
    Ponnambalam S; Endothelial Cell Biology Unit, School of Molecular & Cellular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom.
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    Źródło:
    PloS one [PLoS One] 2014 Nov 13; Vol. 9 (11), pp. e110997. Date of Electronic Publication: 2014 Nov 13 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Angiogenesis Inhibitors/*pharmacology
    Aniline Compounds/*pharmacology
    CDC2 Protein Kinase/*antagonists & inhibitors
    Protein Kinase Inhibitors/*pharmacology
    Triazoles/*pharmacology
    Vascular Endothelial Growth Factor Receptor-2/*antagonists & inhibitors
    Animals ; Breast Neoplasms/blood supply ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Design ; Endothelial Cells/drug effects ; Female ; Humans ; MCF-7 Cells ; Male ; Mice ; Mice, Inbred C57BL ; Neoplasm Metastasis/drug therapy ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Physiologic/drug effects ; Signal Transduction/drug effects ; Wound Healing/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Optimal medical therapy and percutaneous coronary intervention for stable angina: why patients should 'be taking' and 'keep taking' the tablets.
    Autorzy:
    Mohee K; Division of Cardiovascular & Diabetes Research, Leeds Multidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds, UK.
    Wheatcroft SB
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    Źródło:
    Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2014 Aug; Vol. 39 (4), pp. 331-3. Date of Electronic Publication: 2014 Apr 23.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Angina, Stable/*therapy
    Cardiotonic Agents/*therapeutic use
    Percutaneous Coronary Intervention/*methods
    Cardiotonic Agents/administration & dosage ; Combined Modality Therapy ; Coronary Artery Disease/therapy ; Humans ; Medication Adherence ; Randomized Controlled Trials as Topic ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The S100A6 calcium-binding protein regulates endothelial cell-cycle progression and senescence.
    Autorzy:
    Bao L; Endothelial Cell Biology Unit, School of Molecular & Cellular Biology, LIGHT Laboratories, University of Leeds, UK.
    Odell AF
    Stephen SL
    Wheatcroft SB
    Walker JH
    Ponnambalam S
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    Źródło:
    The FEBS journal [FEBS J] 2012 Dec; Vol. 279 (24), pp. 4576-88. Date of Electronic Publication: 2012 Nov 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cell Cycle/*physiology
    Cell Cycle Proteins/*physiology
    Cellular Senescence/*physiology
    S100 Proteins/*physiology
    Cell Cycle Proteins/genetics ; DNA Replication/physiology ; Humans ; RNA, Messenger/genetics ; S100 Calcium Binding Protein A6 ; S100 Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair.
    Autorzy:
    Bruns AF; Endothelial Cell Biology Unit, School for Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom.
    Yuldasheva N
    Latham AM
    Bao L
    Pellet-Many C
    Frankel P
    Stephen SL
    Howell GJ
    Wheatcroft SB
    Kearney MT
    Zachary IC
    Ponnambalam S
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2012; Vol. 7 (11), pp. e48539. Date of Electronic Publication: 2012 Nov 06.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Neovascularization, Physiologic*/drug effects
    Proteolysis*/drug effects
    Signal Transduction*/drug effects
    Wound Healing*/drug effects
    Blood Vessels/*growth & development
    Heat-Shock Proteins/*metabolism
    Vascular Endothelial Growth Factor Receptor-2/*metabolism
    Animals ; Arteries/drug effects ; Arteries/physiology ; Benzoquinones/pharmacology ; Blood Vessels/drug effects ; Blood Vessels/metabolism ; Cell Movement/drug effects ; Clathrin/metabolism ; Endocytosis/drug effects ; HSP70 Heat-Shock Proteins/metabolism ; HSP90 Heat-Shock Proteins/antagonists & inhibitors ; HSP90 Heat-Shock Proteins/metabolism ; Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Intracellular Space/drug effects ; Intracellular Space/metabolism ; Lactams, Macrocyclic/pharmacology ; Mice ; Mice, Inbred C57BL ; Models, Biological ; Protein Stability/drug effects ; Protein Transport/drug effects ; Regeneration/drug effects ; Zebrafish
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular disease.
    Autorzy:
    Stephen SL; Endothelial Cell Biology Unit, Institute of Molecular & Cellular Biology, LIGHT Laboratories, University of Leeds, Clarendon Way, Leeds LS2 9JT, UK.
    Freestone K
    Dunn S
    Twigg MW
    Homer-Vanniasinkam S
    Walker JH
    Wheatcroft SB
    Ponnambalam S
    Pokaż więcej
    Źródło:
    International journal of hypertension [Int J Hypertens] 2010 Aug 17; Vol. 2010, pp. 646929. Date of Electronic Publication: 2010 Aug 17.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Diabetes mellitus and mortality after acute coronary syndrome as a first or recurrent cardiovascular event.
    Autorzy:
    Cubbon RM; Division of Cardiovascular and Diabetes Research, Leeds Institute of Genetics, Health & Therapeutics, The LIGHT Laboratories, The University of Leeds, Leeds, United Kingdom.
    Abbas A
    Wheatcroft SB
    Kilcullen N
    Das R
    Morrell C
    Barth JH
    Kearney MT
    Hall AS
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    Corporate Authors:
    EMMACE-2 investigators
    Źródło:
    PloS one [PLoS One] 2008; Vol. 3 (10), pp. e3483. Date of Electronic Publication: 2008 Oct 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Acute Coronary Syndrome/*complications
    Acute Coronary Syndrome/*mortality
    Diabetes Mellitus/*mortality
    Acute Coronary Syndrome/epidemiology ; Aged ; Case-Control Studies ; Cohort Studies ; Diabetes Mellitus/epidemiology ; Female ; Humans ; Male ; Mortality ; Retrospective Studies ; Troponin I/blood ; United Kingdom
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-18 z 18

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