- Tytuł:
- Dynamic assembly of the mRNA m6A methyltransferase complex is regulated by METTL3 phase separation.
- Autorzy:
- Źródło:
- PLoS biology [PLoS Biol] 2022 Feb 10; Vol. 20 (2), pp. e3001535. Date of Electronic Publication: 2022 Feb 10 (Print Publication: 2022).
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Cell Nucleus/*metabolism
Methyltransferases/*metabolism
RNA, Messenger/*metabolism
Catalytic Domain ; Cell Line, Tumor ; Cell Nucleus/genetics ; Cryptochromes/genetics ; Cryptochromes/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Methyltransferases/chemistry ; Methyltransferases/genetics ; Microscopy, Confocal ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/genetics ; Multiprotein Complexes/metabolism ; Mutation ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Protein Binding ; RNA, Messenger/genetics ; S-Adenosylmethionine/metabolism ; Red Fluorescent Protein
Czasopismo naukowe