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Wyszukujesz frazę ""Wnt Signaling Pathway"" wg kryterium: Temat

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Tytuł:
Expression Levels of WNT Signaling Pathway Genes During Early Tooth Development.
Autorzy:
Song Y; Department of oral mucosa, Shanghai Stomatological Hospital, Fudan University, Shanghai, P. R. China.; Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital, Fudan University, Shanghai, P. R. China.
Song F; Department of first dental clinic, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai, China.
Xiao X; Department of oral mucosa, Shanghai Stomatological Hospital, Fudan University, Shanghai, P. R. China.; Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital, Fudan University, Shanghai, P. R. China.
Song Z; Department of oral mucosa, Shanghai Stomatological Hospital, Fudan University, Shanghai, P. R. China.; Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital, Fudan University, Shanghai, P. R. China.
Liu S; Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital, Fudan University, Shanghai, P. R. China.
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Źródło:
Organogenesis [Organogenesis] 2023 Dec 31; Vol. 19 (1), pp. 2212583.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Wnt Signaling Pathway*
Tooth*
Rats ; Animals ; Odontogenesis/genetics ; Wnt Proteins/genetics ; Wnt Proteins/metabolism ; Molar/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
The role of Wnt signaling in mesenchymal stromal cell-driven angiogenesis.
Autorzy:
Mankuzhy P; Department of Surgery and Centre for Medical Research, Faculty of Health and Medical Sciences, The University of Western Australia, 6009 Perth, Australia; College of Veterinary and Animal Sciences - Mannuthy, Kerala Veterinary and Animal Sciences University, Pookode, Wayanad, Kerala 673576 India. Electronic address: .
Dharmarajan A; Department of Biomedical Sciences, Sri Ramachandra faculty of Biomedical Sciences, Technology and Research, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai 600116, India; School of Pharmacy and Biomedical Sciences, Curtin University, Bentley, Perth, Western Australia, Australia; School of Human Sciences, Faculty of Life Sciences, University of Western Australia, 6009 Perth, Australia.
Perumalsamy LR; Department of Biomedical Sciences, Sri Ramachandra faculty of Biomedical Sciences, Technology and Research, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai 600116, India.
Sharun K; Division of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.
Samji P; Department of Biomedical Sciences, Sri Ramachandra faculty of Biomedical Sciences, Technology and Research, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai 600116, India.
Dilley RJ; Department of Surgery and Centre for Medical Research, Faculty of Health and Medical Sciences, The University of Western Australia, 6009 Perth, Australia.
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Źródło:
Tissue & cell [Tissue Cell] 2023 Dec; Vol. 85, pp. 102240. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Wnt Signaling Pathway*
Mesenchymal Stem Cells*
Cell Differentiation ; Cell Movement
Czasopismo naukowe
Szczegóły
Tytuł:
Novel treatment from a botanical formulation Si-Miao-Yong-an decoction inhibits vasa vasorum angiogenesis and stabilizes atherosclerosis plaques via the Wnt1/β-catenin signalling pathway.
Autorzy:
Qi Z; Postdoctoral Research Station of China Academy of Chinese Medical Sciences, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, P.R. China.; Institute of Gerontology, China Academy of Chinese Medical Sciences, Beijing, P.R. China.; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China.
Yan Z; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China.
Zhu K; Zhengzhou Hospital of Traditional Chinese Medicine, Zhengzhou, P.R. China.
Wang Y; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China.
Fan Y; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China.
Li T; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China.
Zhang J; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2023 Dec; Vol. 61 (1), pp. 1364-1373.
Typ publikacji:
Journal Article
MeSH Terms:
Atherosclerosis*/drug therapy
Wnt Signaling Pathway*
Animals ; Male ; Mice ; beta Catenin ; Cyclin D1 ; RNA, Messenger ; Vasa Vasorum
Czasopismo naukowe
Szczegóły
Tytuł:
PTEN/AKT and Wnt/β-catenin signaling pathways regulate the proliferation of Lgr5+ cells in liver cancer.
Autorzy:
He J; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China; Department of Anesthesiology, The First People's Hospital of Foshan, Foshan, China.
Han J; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China.
Lin K; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China.
Wang J; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China.
Li G; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China.
Li X; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
Gao Y; Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China; Department of Anesthesiology, The First People's Hospital of Foshan, Foshan, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Nov 26; Vol. 683, pp. 149117. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Wnt Signaling Pathway*
Liver Neoplasms*/pathology
Male ; Animals ; Mice ; Proto-Oncogene Proteins c-akt/metabolism ; beta Catenin/metabolism ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism ; Neoplastic Stem Cells/pathology ; Cell Proliferation
Czasopismo naukowe
Szczegóły
Tytuł:
Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2.
Autorzy:
Colozza G; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.
Lee H; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.; Center for Genome Engineering, Institute for Basic Science, 55, Expo-ro, Yuseong-gu, Daejeon 34126, Republic of Korea.
Merenda A; HUB Organoids, Utrecht, Netherlands.
Wu SS; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.
Català-Bordes A; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.
Radaszkiewicz TW; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Jordens I; Oncode Institute and Centre for Molecular Medicine, University Medical Centre Utrecht, Utrecht, Netherlands.
Lee JH; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.; Center for Genome Engineering, Institute for Basic Science, 55, Expo-ro, Yuseong-gu, Daejeon 34126, Republic of Korea.
Bamford AD; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.; Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland.
Farnhammer F; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.; Division of Metabolism and Division of Oncology, University Children's Hospital Zurich and Children's Research Center, University of Zurich, 8032 Zurich, Switzerland.
Low TY; UKM Medical Molecular Biology Institute (UMBI), University Kebangsaan Malaysia (UKM), Jalan Yaacob Latiff, Bandar Tun Razak, 56000 Kuala Lumpur, Malaysia.
Maurice MM; Oncode Institute and Centre for Molecular Medicine, University Medical Centre Utrecht, Utrecht, Netherlands.
Bryja V; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.; Department of Cytokinetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic.
Kim J; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.; Department of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, Republic of Korea.
Koo BK; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.; Center for Genome Engineering, Institute for Basic Science, 55, Expo-ro, Yuseong-gu, Daejeon 34126, Republic of Korea.; Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea.
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Źródło:
Science advances [Sci Adv] 2023 Nov 24; Vol. 9 (47), pp. eadh9673. Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
Paneth Cells*
Animals ; Intestines ; Cell Differentiation ; Stem Cells/metabolism ; Mammals
Czasopismo naukowe
Szczegóły
Tytuł:
USP10 strikes down β-catenin by dual-wielding deubiquitinase activity and phase separation potential.
Autorzy:
Wang Y; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Mao A; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou 510006, China; Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou University, Shantou, Guangdong 515063, China.
Liu J; College of Basic Medical Science, China Medical University, Shenyang 110122, China.
Li P; Key Laboratory for Biomedical Photonics of MOE at Wuhan National Laboratory for Optoelectronics - Hubei Bioinformatics and Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Zheng S; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Tong T; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Li Z; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Zhang H; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Ma L; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Lin J; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Pang Z; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Han Q; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Qi F; Key Laboratory for Biomedical Photonics of MOE at Wuhan National Laboratory for Optoelectronics - Hubei Bioinformatics and Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Zhang X; Key Laboratory of Molecular Biophysics of the Ministry of Education, National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Chen M; F.M Kirby Neurobiology Center, Boston Children's Hospital, Department of Neurology, Harvard Medical School, Boston, MA 02115, USA.
He X; F.M Kirby Neurobiology Center, Boston Children's Hospital, Department of Neurology, Harvard Medical School, Boston, MA 02115, USA.
Zhang X; College of Sciences, Northeastern University, Shenyang 110004, China.
Fei T; College of Life and Health Science, Northeastern University, Shenyang 110819, China.
Liu BF; Key Laboratory for Biomedical Photonics of MOE at Wuhan National Laboratory for Optoelectronics - Hubei Bioinformatics and Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Gao D; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China.
Cao L; College of Basic Medical Science, China Medical University, Shenyang 110122, China. Electronic address: .
Wang Q; Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou 510006, China. Electronic address: .
Li Y; Key Laboratory for Biomedical Photonics of MOE at Wuhan National Laboratory for Optoelectronics - Hubei Bioinformatics and Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China. Electronic address: .
Sheng R; College of Life and Health Science, Northeastern University, Shenyang 110819, China. Electronic address: .
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Źródło:
Cell chemical biology [Cell Chem Biol] 2023 Nov 16; Vol. 30 (11), pp. 1436-1452.e10. Date of Electronic Publication: 2023 Aug 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
beta Catenin*/metabolism
Wnt Signaling Pathway*
Deubiquitinating Enzymes/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
RNF2 regulates Wnt/ß-catenin signaling via TCF7L1 destabilization.
Autorzy:
Koo Y; Department of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Republic of Korea.
Han W; F. M. Kirby Neurobiology Center, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Keum BR; Department of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Republic of Korea.
Lutz L; Department of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Republic of Korea.
Yun SH; Center for Research Equipment, Korea Basic Science Institute, Cheongju, 28119, Republic of Korea.
Kim GH; Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju, 28119, Republic of Korea.
Han JK; Department of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 13; Vol. 13 (1), pp. 19750. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Wnt Signaling Pathway*
Catenins*/metabolism
Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitination ; beta Catenin/genetics ; beta Catenin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling.
Autorzy:
Qi X; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: .
Hu Q; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Elghobashi-Meinhardt N; School of Chemistry, University College Dublin, South Belfield, Dublin 4, Ireland.
Long T; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Chen H; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Li X; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: .
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Źródło:
Cell [Cell] 2023 Nov 09; Vol. 186 (23), pp. 5028-5040.e14. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, G-Protein-Coupled*/metabolism
Wnt Signaling Pathway*
Wnt Proteins*/chemistry
Wnt Proteins*/metabolism
Blood-Brain Barrier/metabolism ; Protein Binding ; Humans
Czasopismo naukowe
Szczegóły
Tytuł:
ROR2 homodimerization is sufficient to activate a neuronal Wnt/calcium signaling pathway.
Autorzy:
Riquelme R; Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, Washington, USA.
Li L; Neuroscience Undergraduate Program, University of Washington, Seattle, Washington, USA.
Gambrill A; Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, Washington, USA.
Barria A; Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, Washington, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Nov; Vol. 299 (11), pp. 105350. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
Wnt Proteins*/genetics
Wnt Proteins*/metabolism
Animals ; Calcium/metabolism ; Calcium Signaling ; Receptor Tyrosine Kinase-like Orphan Receptors/genetics ; Wnt-5a Protein/metabolism ; Receptors, G-Protein-Coupled/metabolism ; Neurons/metabolism ; Frizzled Receptors/genetics ; Frizzled Receptors/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Wnt signaling in periodontitis.
Autorzy:
Güney Z; Faculty of Dentistry Department of Periodontology, Ankara University, 06500-Cankaya, Ankara, Turkey.; Faculty of Dentistry Department of Periodontology, Ankara Medipol University, Ankara, Turkey.
Kurgan Ş; Faculty of Dentistry Department of Periodontology, Ankara University, 06500-Cankaya, Ankara, Turkey. .
Önder C; Faculty of Dentistry Department of Periodontology, Ankara University, 06500-Cankaya, Ankara, Turkey.
Tayman MA; Faculty of Dentistry Department of Periodontology, Yildirim Beyazit University, Ankara, Turkey.
Günhan Ö; Faculty of Medicine Department of Pathology, TOBB University, Ankara, Turkey.
Kantarci A; The Forsyth Institute, Cambridge, MA, USA.
Serdar MA; Faculty of Medicine, Department of Biochemistry, Acibadem University, Istanbul, Turkey.
Günhan M; Faculty of Dentistry Department of Periodontology, Ankara University, 06500-Cankaya, Ankara, Turkey.
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Źródło:
Clinical oral investigations [Clin Oral Investig] 2023 Nov; Vol. 27 (11), pp. 6801-6812. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
Periodontitis*/metabolism
Humans ; beta Catenin/metabolism ; Gingiva/metabolism ; Inflammation/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Super-enhancer-associated SNHG15 cooperating with FOSL1 contributes to bladder cancer progression through the WNT pathway.
Autorzy:
Tan M; Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Pan Q; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Gong H; Department of Urology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China.
Zhai X; Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Wan Z; Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Ge M; Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Gu J; Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhang D; Department of Urology, Shanghai Pudong New Area People's Hospital, Shanghai 201299, China. Electronic address: .
Chen X; Department of Endocrinology, Gongli Hospital of Shanghai Pudong New Area, Shanghai 200135, China. Electronic address: .
Xu D; Department of Urology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: dr_.
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Źródło:
Pharmacological research [Pharmacol Res] 2023 Nov; Vol. 197, pp. 106940. Date of Electronic Publication: 2023 Sep 26.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
Urinary Bladder Neoplasms*/genetics
Humans ; Animals ; Mice ; Urinary Bladder ; Epithelial Cells ; Apoptosis
Czasopismo naukowe
Szczegóły
Tytuł:
Anti-Pan-Rspo Chimeric Protein-Conjugated Albumin Nanoparticle Provides Promising Opportunities in Cancer Targeted Therapy.
Autorzy:
Zheng S; College of Life and Health Science, Northeastern University, 195 Chuangxin Road, Shenyang, Liaoning, 110819, China.
Zhang X; College of Science, Northeastern University, 3-11 Wenhua Road, Shenyang, Liaoning, 110004, China.
Pang Z; College of Life and Health Science, Northeastern University, 195 Chuangxin Road, Shenyang, Liaoning, 110819, China.
Liu J; College of Life and Health Science, Northeastern University, 195 Chuangxin Road, Shenyang, Liaoning, 110819, China.
Liu S; College of Life and Health Science, Northeastern University, 195 Chuangxin Road, Shenyang, Liaoning, 110819, China.
Sheng R; College of Life and Health Science, Northeastern University, 195 Chuangxin Road, Shenyang, Liaoning, 110819, China.
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Źródło:
Advanced healthcare materials [Adv Healthc Mater] 2023 Nov; Vol. 12 (29), pp. e2301441. Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*/physiology
Neoplasms*/drug therapy
Humans ; Albumins ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/pharmacology ; Recombinant Fusion Proteins/therapeutic use
Czasopismo naukowe
Szczegóły
Tytuł:
G protein-coupled receptor 17 is regulated by WNT pathway during oligodendrocyte precursor cell differentiation.
Autorzy:
Boccazzi M; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France; Laboratory of Molecular and Cellular Pharmacology of Purinergic Transmission, Department of Pharmaceutical Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Macchiarulo G; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France.
Lebon S; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France.
Janowska J; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France; NeuroRepair Department, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland.
Le Charpentier T; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France.
Faivre V; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France.
Hua J; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France.
Marangon D; Laboratory of Molecular and Cellular Pharmacology of Purinergic Transmission, Department of Pharmaceutical Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Lecca D; Laboratory of Molecular and Cellular Pharmacology of Purinergic Transmission, Department of Pharmaceutical Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Fumagalli M; Department of Pharmacological and Biomolecular Sciences 'Rodolfo Paoletti', Università degli Studi di Milano, 20133 Milan, Italy.
Mani S; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France.
Abbracchio MP; Laboratory of Molecular and Cellular Pharmacology of Purinergic Transmission, Department of Pharmaceutical Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Gressens P; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France.
Schang AL; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France; Université Paris Cité, UMR 1153 CRESS, Paris, France. Electronic address: .
Van Steenwinckel J; Université Paris Cité, Inserm, NeuroDiderot, F-75019 Paris, France.
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Źródło:
Neurobiology of disease [Neurobiol Dis] 2023 Oct 15; Vol. 187, pp. 106315. Date of Electronic Publication: 2023 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
Oligodendrocyte Precursor Cells*/metabolism
Mice ; Animals ; beta Catenin/metabolism ; Receptor, Platelet-Derived Growth Factor alpha/metabolism ; Nerve Tissue Proteins/genetics ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism ; Cell Differentiation/physiology ; Oligodendroglia/metabolism ; RNA, Messenger/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Secreted frizzled-related protein 5: A promising therapeutic target for metabolic diseases via regulation of Wnt signaling.
Autorzy:
Song Y; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.
Ma Y; Department of Pathophysiology, School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, China.
Zhang K; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.
Zhang W; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Department of Pathology, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.
Xiong G; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.
Qi T; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.
Shi J; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.
Qiu H; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.
Zhang J; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.
Han F; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Department of Pathology, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China.
Kan C; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China. Electronic address: .
Sun X; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, 261031, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Oct 15; Vol. 677, pp. 70-76. Date of Electronic Publication: 2023 Aug 03.
Typ publikacji:
Review; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Wnt Signaling Pathway*
Insulin Resistance*
Humans ; Secreted Frizzled-Related Proteins ; Eye Proteins/metabolism ; Membrane Proteins/metabolism ; Adaptor Proteins, Signal Transducing/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors.
Autorzy:
Zhang B; Department of Neurosurgery, Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Zhao C; Department of Neurosurgery, Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Shen W; Department of Neurosurgery, Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Li W; Department of Neurosurgery, Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Zheng Y; Department of Neurosurgery, Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Kong X; Department of Neurosurgery, Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Wang J; Department of Neurosurgery, Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Wu X; Department of Cell Biology, Tianjin Medical University, Tianjin, China.; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Zeng T; Department of Neurosurgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China. .
Liu Y; Department of Neurosurgery, Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China. .
Zhou Y; Department of Neurosurgery, Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China. .
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Źródło:
Nature communications [Nat Commun] 2023 Oct 14; Vol. 14 (1), pp. 6489. Date of Electronic Publication: 2023 Oct 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hippocampus*
Wnt Signaling Pathway*/genetics
Animals ; Humans ; Mice ; Cell Differentiation/genetics ; Neurogenesis/genetics ; Polycomb-Group Proteins
Czasopismo naukowe
Szczegóły
Tytuł:
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6.
Autorzy:
Spencer ZT; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.
Ng VH; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Benchabane H; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.
Siddiqui GS; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.
Duwadi D; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.
Maines B; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.
Bryant JM; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Schwarzkopf A; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Yuan K; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.
Kassel SN; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Mishra A; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.
Pimentel A; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.
Lebensohn AM; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Rohatgi R; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Gerber SA; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, 03766, USA.
Robbins DJ; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA.
Lee E; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA. .
Ahmed Y; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Oct 05; Vol. 14 (1), pp. 6174. Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Wnt Signaling Pathway*
Drosophila Proteins*/metabolism
Animals ; Wnt1 Protein/genetics ; Wnt1 Protein/metabolism ; Drosophila/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling.
Autorzy:
Ng VH; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.; Program in Cancer Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Spencer Z; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, 03755, USA.
Neitzel LR; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Nayak A; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA.
Loberg MA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Shen C; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA.
Kassel SN; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Kroh HK; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
An Z; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94158, USA.
Anthony CC; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Bryant JM; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Lawson A; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Goldsmith L; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Benchabane H; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, 03755, USA.
Hansen AG; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.; STEMCELL Technologies, 1618 Station Street, Vancouver, BC, V6A 1B6, Canada.
Li J; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
D'Souza S; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
Lebensohn AM; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Rohatgi R; Departments of Biochemistry, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Weiss WA; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94158, USA.
Weiss VL; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Williams C; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Hong CC; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Robbins DJ; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA.
Ahmed Y; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, 03755, USA. .
Lee E; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA. .; Program in Cancer Biology, Vanderbilt University, Nashville, TN, 37232, USA. .; Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Oct 05; Vol. 14 (1), pp. 6173. Date of Electronic Publication: 2023 Oct 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
beta Catenin*/genetics
beta Catenin*/metabolism
Wnt Signaling Pathway*
Endopeptidases*/metabolism
Animals ; Humans ; Ligases/metabolism ; Low Density Lipoprotein Receptor-Related Protein-6/genetics ; Low Density Lipoprotein Receptor-Related Protein-6/metabolism ; Receptors, Wnt ; Ubiquitin ; Zebrafish/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Autorzy:
Wu Y; Department of Pathology, Pingshan District People's Hospital of Shenzhen, Pingshan General Hospital of Southern Medical University, Shenzhen 518118, China. Electronic address: .
Chen W; Department of Pathology, Pingshan District People's Hospital of Shenzhen, Pingshan General Hospital of Southern Medical University, Shenzhen 518118, China.
Zhang B; Department of Pathology, Pingshan District People's Hospital of Shenzhen, Pingshan General Hospital of Southern Medical University, Shenzhen 518118, China.
Liu H; Department of Pathology, Pingshan District People's Hospital of Shenzhen, Pingshan General Hospital of Southern Medical University, Shenzhen 518118, China.
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Źródło:
Tissue & cell [Tissue Cell] 2023 Oct; Vol. 84, pp. 102193. Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*/genetics
Thyroid Neoplasms*/metabolism
Female ; Animals ; Mice ; Thyroid Cancer, Papillary/pathology ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Movement/genetics ; beta Catenin/metabolism ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Szczegóły
Tytuł:
PCBP1-mediated regulation of WNT signaling is critical for breast tumorigenesis.
Autorzy:
Yang ZY; Department of Breast Surgery, China-Japan Union Hospital of Jilin University, No.126, Xiantai Street, Changchun, Jilin, 130033, China.
Zhang WL; Department of Hematology and Oncology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China.
Jiang CW; Department of Pathology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China.
Sun G; Department of Breast Surgery, China-Japan Union Hospital of Jilin University, No.126, Xiantai Street, Changchun, Jilin, 130033, China. .
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Źródło:
Cell biology and toxicology [Cell Biol Toxicol] 2023 Oct; Vol. 39 (5), pp. 2331-2343. Date of Electronic Publication: 2022 May 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*
Wnt Signaling Pathway*
Animals ; Female ; Humans ; Mice ; Carcinogenesis ; Cell Transformation, Neoplastic ; DNA-Binding Proteins ; RNA-Binding Proteins/genetics ; Tumor Microenvironment
Czasopismo naukowe
Szczegóły
Tytuł:
Secreted frizzled-related proteins: A promising therapeutic target for cancer therapy through Wnt signaling inhibition.
Autorzy:
Zhang W; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Department of Pathology, Affiliated Hospital of Weifang Medical University, Weifang 261031, China.
Zhang K; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China.
Ma Y; Department of Pathology, Affiliated Hospital of Weifang Medical University, Weifang 261031, China.
Song Y; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China.
Qi T; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China.
Xiong G; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China.
Zhang Y; Department of Pathology, Affiliated Hospital of Weifang Medical University, Weifang 261031, China.
Kan C; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China.
Zhang J; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China. Electronic address: .
Han F; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Department of Pathology, Affiliated Hospital of Weifang Medical University, Weifang 261031, China. Electronic address: .
Sun X; Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang 261031, China; Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang 261031, China. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Oct; Vol. 166, pp. 115344. Date of Electronic Publication: 2023 Aug 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Wnt Signaling Pathway*
Neoplasms*/drug therapy
Neoplasms*/genetics
Adult ; Female ; Pregnancy ; Humans ; Secreted Frizzled-Related Proteins ; Ligands ; Homeostasis ; Frizzled Receptors/genetics
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 13216

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