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Wyszukujesz frazę ""Wnt Signaling Pathway"" wg kryterium: Temat


Tytuł:
WNT6 participates in the occurrence and development of ovarian cancer by upregulating/activating the typical Wnt pathway and Notch1 signaling pathway.
Autorzy:
Bao H; Department of Obstetrics and Gynecology, Department of Gynecologic Oncology Research Office, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
Wu W; Department of Obstetrics and Gynecology, Department of Gynecologic Oncology Research Office, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
Li Y; Department of Obstetrics and Gynecology, Department of Gynecologic Oncology Research Office, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
Zong Z; Department of Obstetrics and Gynecology, Department of Gynecologic Oncology Research Office, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China; China Medical University, Shenyang 110001, China. Electronic address: zongzhi_.
Chen S; Department of Obstetrics and Gynecology, Department of Gynecologic Oncology Research Office, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China. Electronic address: .
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Źródło:
Gene [Gene] 2022 Dec 20; Vol. 846, pp. 146871. Date of Electronic Publication: 2022 Sep 06.
Typ publikacji:
Journal Article
MeSH Terms:
Ovarian Neoplasms*/metabolism
Wnt Signaling Pathway*
Apoptosis ; Carcinoma, Ovarian Epithelial/genetics ; Cell Line, Tumor ; Cell Proliferation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; RNA, Messenger ; Receptor, Notch1/genetics ; Receptor, Notch1/metabolism ; Wnt Proteins/genetics ; Wnt Proteins/metabolism ; beta Catenin/genetics ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł:
Effect of VD3 on cell proliferation and the Wnt signaling pathway in bovine endometrial epithelial cells treated with lipopolysaccharide.
Autorzy:
Zhang F; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China. Electronic address: .
Zhang J; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China. Electronic address: .
Li J; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China.
Yan P; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China.
Li Y; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China.
Zhang Y; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China.
Zhuang Y; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China.
Zhou J; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China.
Deng L; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China.
Zhang Z; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, China. Electronic address: .
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Źródło:
Theriogenology [Theriogenology] 2022 Nov; Vol. 193, pp. 68-76. Date of Electronic Publication: 2022 Sep 17.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*/genetics
beta Catenin*/metabolism
Animals ; Cattle ; Cell Proliferation ; Cholecalciferol/pharmacology ; Epithelial Cells/metabolism ; Female ; Lipopolysaccharides/pharmacology ; Proliferating Cell Nuclear Antigen/metabolism ; Sincalide/metabolism ; Sincalide/pharmacology
Czasopismo naukowe
Tytuł:
Canonical Wnt/β-catenin signaling has positive effects on osteogenesis, but can have negative effects on cementogenesis.
Autorzy:
Li T; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Wang H; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Jiang Y; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Guan Y; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Chen S; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Wu Z; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Zou S; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Bonewald LF; Departments of Anatomy, Cell Biology & Physiology and Orthopaedic Surgery, Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Duan P; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
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Źródło:
Journal of periodontology [J Periodontol] 2022 Nov; Vol. 93 (11), pp. 1725-1737. Date of Electronic Publication: 2022 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Cementogenesis*
Wnt Signaling Pathway*
Mice ; Animals ; Osteogenesis ; beta Catenin/genetics ; beta Catenin/metabolism ; beta Catenin/pharmacology ; Cell Differentiation ; Alkaline Phosphatase/metabolism ; RNA, Messenger
Czasopismo naukowe
Tytuł:
SAT2 regulates Sertoli cell-germline interactions via STIM1-mediated ROS/WNT/β-catenin signaling pathway.
Autorzy:
Chen X; Department of Obstetrics and Gynecology, Affiliated Hospital 2 of Nantong University and First People's Hospital of Nantong City, Nantong, Jiangsu, China.
Zheng Y; Department of Obstetrics and Gynecology, Affiliated Hospital 2 of Nantong University and First People's Hospital of Nantong City, Nantong, Jiangsu, China.
Han Y; Department of Obstetrics and Gynecology, Affiliated Hospital 2 of Nantong University and First People's Hospital of Nantong City, Nantong, Jiangsu, China.
He H; Department of Human Anatomy, School of Medicine, Nantong University, Nantong, China.
Lv J; Suzhou Dushu Lake Hospital (Dushu Lake Hospital Affiliated to Soochow University), Suzhou, China.
Yu J; Institute of Reproductive Medicine, School of Medicine, Nantong University, Nantong, China.
Li H; State Key Laboratory of Reproductive Medicine, Center for Reproduction and Genetics, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School, Nanjing Medical University, Suzhou, China.
Hou S; Department of Gynaecology, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School, Nanjing Medical University, Suzhou, China.
Shen C; State Key Laboratory of Reproductive Medicine, Center for Reproduction and Genetics, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School, Nanjing Medical University, Suzhou, China.
Zheng B; State Key Laboratory of Reproductive Medicine, Center for Reproduction and Genetics, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School, Nanjing Medical University, Suzhou, China.
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Źródło:
Cell biology international [Cell Biol Int] 2022 Oct; Vol. 46 (10), pp. 1704-1713. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article
MeSH Terms:
Acetyltransferases*/metabolism
Sertoli Cells*/metabolism
Stromal Interaction Molecule 1*/metabolism
Wnt Signaling Pathway*
Animals ; Germ Cells/metabolism ; Male ; Mice ; Reactive Oxygen Species/metabolism ; Spermatogenesis/physiology ; Testis/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł:
Relaxin inhibits renal fibrosis and the epithelial-to-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Autorzy:
Feiteng C; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lei C; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Deng L; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chaoliang X; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zijie X; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi S; Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Minglei S; Department of Geriatric, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło:
Renal failure [Ren Fail] 2022 Dec; Vol. 44 (1), pp. 513-524.
Typ publikacji:
Journal Article
MeSH Terms:
Renal Insufficiency, Chronic*/pathology
Wnt Signaling Pathway*
Relaxin/*metabolism
Animals ; Disease Models, Animal ; Epithelial-Mesenchymal Transition ; Fibrosis ; Humans ; Mice
Czasopismo naukowe
Tytuł:
Porcn as a novel therapeutic target in cancer therapy:  A review.
Autorzy:
Raeisi M; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Saberivand M; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Velaei K; Department of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Aghaei N; Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.; Imam Sajjad Hospital, Tabriz, Iran.
Rahimi-Farsi N; Department of Biology, University College of Nabi Akram, Tabriz, Iran.
Kharrati-Shishavan H; Department of Plant Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Hassanzadeh D; Department of Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Mehdizadeh A; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
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Źródło:
Cell biology international [Cell Biol Int] 2022 Dec; Vol. 46 (12), pp. 1979-1991. Date of Electronic Publication: 2022 Aug 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Wnt Signaling Pathway*
Neoplasms*/drug therapy
Humans ; Membrane Proteins/metabolism ; Acyltransferases
Czasopismo naukowe
Tytuł:
Wnt signalling in cell division: from mechanisms to tissue engineering.
Autorzy:
Habib SJ; Department of Biomedical Sciences, University of Lausanne, Rue du Bugnon 7a, CH-1005 Lausanne, Switzerland. Electronic address: .
Acebrón SP; Centre for Organismal Studies (COS), University of Heidelberg, Im Neuenheimer Feld 230, 69120 Heidelberg, Germany. Electronic address: .
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Źródło:
Trends in cell biology [Trends Cell Biol] 2022 Dec; Vol. 32 (12), pp. 1035-1048. Date of Electronic Publication: 2022 Jun 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Tissue Engineering*
Wnt Signaling Pathway*
Humans ; Mitosis ; Chromosome Segregation ; Asymmetric Cell Division ; Spindle Apparatus/physiology
Czasopismo naukowe
Tytuł:
CD146 at the Interface between Oxidative Stress and the Wnt Signaling Pathway in Systemic Sclerosis.
Autorzy:
Heim X; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France; Service d'immunologie, Biogénopôle, Hôpital de la Timone, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France. Electronic address: .
Bermudez J; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Joshkon A; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Kaspi E; Aix Marseille University, APHM, INSERM, MMG, Hôpital la Timone, Service de Biologie Cellulaire, Marseille, France.
Bachelier R; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Nollet M; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Vélier M; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France; Hematology and Vascular Biology Department, Hopital de la Conception, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France.
Dou L; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Brodovitch A; Service d'immunologie, Biogénopôle, Hôpital de la Timone, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France.
Foucault-Bertaud A; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Leroyer AS; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Benyamine A; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France; Internal Medicine Department, Hopital Nord, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France.
Daumas A; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France; Internal Medicine, Geriatric and Therapeutic Department, Hopital de la Timone, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France.
Granel B; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France; Internal Medicine Department, Hopital Nord, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France.
Sabatier F; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France; Cell Therapy Laboratory, INSERM CIC BT 1409, Hôpital de la Conception, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France.
Dignat-George F; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France; Hematology and Vascular Biology Department, Hopital de la Conception, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France.
Blot-Chabaud M; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Bardin N; Aix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France; Service d'immunologie, Biogénopôle, Hôpital de la Timone, Assistance Publique des Hôpitaux de Marseille (AP-HM), Marseille, France.
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Źródło:
The Journal of investigative dermatology [J Invest Dermatol] 2022 Dec; Vol. 142 (12), pp. 3200-3210.e5. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*/physiology
Scleroderma, Systemic*/genetics
Scleroderma, Systemic*/metabolism
Humans ; Animals ; Mice ; CD146 Antigen/genetics ; CD146 Antigen/metabolism ; Reactive Oxygen Species/metabolism ; Ligands ; Fibroblasts/metabolism ; Fibrosis ; Oxidative Stress
Czasopismo naukowe
Tytuł:
5-HMF affects cardiovascular development in zebrafish larvae via reactive oxygen species and Wnt signaling pathways.
Autorzy:
Jiang Y; Department of General Practice, The Affiliated Wuxi Clinical College of Nantong University, Jiangsu, China; The Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Geng N; Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Wang M; Murui Biological Technology Co., Ltd., Suzhou Industrial Park, No 11 Jinpu road, Suzhou, China.
Wu W; Department of General Practice, The Affiliated Wuxi Clinical College of Nantong University, Jiangsu, China.
Feng N; Department of General Practice, The Affiliated Wuxi Clinical College of Nantong University, Jiangsu, China. Electronic address: .
Zhang X; Wuxi Hospital of Traditional Chinese Medicine, Wuxi, Jiangsu, China. Electronic address: .
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Źródło:
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP [Comp Biochem Physiol C Toxicol Pharmacol] 2022 Dec; Vol. 262, pp. 109452. Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
Zebrafish*/metabolism
Acetylcysteine/metabolism ; Acetylcysteine/pharmacology ; Aldehydes/metabolism ; Aldehydes/pharmacology ; Animals ; Antioxidants/metabolism ; Embryo, Nonmammalian ; Humans ; Larva/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
TRIM46 upregulates Wnt/β-catenin signaling by inhibiting Axin1 to mediate hypoxia-induced epithelial-mesenchymal transition in HK2 cells.
Autorzy:
Liao L; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Duan L; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Guo Y; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Zhou B; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Xu Q; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Zhang C; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Liu W; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Liu W; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Liu Z; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Hu J; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Chen J; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China. sea_.
Lu J; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China. .
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Źródło:
Molecular and cellular biochemistry [Mol Cell Biochem] 2022 Dec; Vol. 477 (12), pp. 2829-2839. Date of Electronic Publication: 2022 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*
Kidney Diseases*/metabolism
Wnt Signaling Pathway*
Animals ; Humans ; Rats ; Axin Protein/genetics ; beta Catenin/metabolism ; Fibrosis ; Hypoxia
Czasopismo naukowe
Tytuł:
Wnt signaling promotes tooth germ development through YAP1-TGF-β signaling.
Autorzy:
Nagano R; Laboratory of Oral Pathology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan; Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Fujii S; Laboratory of Oral Pathology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan; Dento-craniofacial Development and Regeneration Research Center, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: .
Hasegawa K; Laboratory of Oral Pathology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Maeda H; Department of Endodontology and Operative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Kiyoshima T; Laboratory of Oral Pathology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Nov 19; Vol. 630, pp. 64-70. Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tooth*/metabolism
Wnt Signaling Pathway*
Semaphorin-3A/metabolism ; Tooth Germ ; Transforming Growth Factor beta2/metabolism ; YAP-Signaling Proteins/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł:
MICAL1 facilitates pancreatic cancer proliferation, migration, and invasion by activating WNT/β-catenin pathway.
Autorzy:
Cai K; Department of Hepatic-Biliary-Pancreatic Surgery, The Affiliated Hospital of Guizhou Medical University, No.28 Guiyi Street, Yunyan District, Guiyang, 550001, Guizhou, China.; College of Clinical Medicine, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Institute of Hepatobiliary, Pancreatic and Splenic Diseases, Guiyang, China.; Key Laboratory of Liver, Gallbladder, Pancreas and Spleen, Guizhou Medical University, Guiyang, China.
Deng L; Guizhou Provincial Staff Hospital, Guiyang, China.
Zheng D; Department of Hepatic-Biliary-Pancreatic Surgery, The Affiliated Hospital of Guizhou Medical University, No.28 Guiyi Street, Yunyan District, Guiyang, 550001, Guizhou, China.; College of Basic Medicine, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Institute of Hepatobiliary, Pancreatic and Splenic Diseases, Guiyang, China.; Key Laboratory of Liver, Gallbladder, Pancreas and Spleen, Guizhou Medical University, Guiyang, China.
Li L; Department of Hepatic-Biliary-Pancreatic Surgery, The Affiliated Hospital of Guizhou Medical University, No.28 Guiyi Street, Yunyan District, Guiyang, 550001, Guizhou, China.; College of Basic Medicine, Guizhou Medical University, Guiyang, China.; Guizhou Provincial Institute of Hepatobiliary, Pancreatic and Splenic Diseases, Guiyang, China.; Key Laboratory of Liver, Gallbladder, Pancreas and Spleen, Guizhou Medical University, Guiyang, China.
He Z; Department of Hepatobiliary Surgery, Shenzhen Key Laboratory, Shenzhen University General Hospital, Xueyuan AVE 1098, Nanshan District, Shenzhen, 518055, Guangdong, China. .; Shenzhen University Clinical Medical Academy Center, Shenzhen University, Shenzhen, China. .
Yu C; Department of Hepatic-Biliary-Pancreatic Surgery, The Affiliated Hospital of Guizhou Medical University, No.28 Guiyi Street, Yunyan District, Guiyang, 550001, Guizhou, China. .; College of Clinical Medicine, Guizhou Medical University, Guiyang, China. .; Guizhou Provincial Institute of Hepatobiliary, Pancreatic and Splenic Diseases, Guiyang, China. .; Key Laboratory of Liver, Gallbladder, Pancreas and Spleen, Guizhou Medical University, Guiyang, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2022 Nov 12; Vol. 20 (1), pp. 528. Date of Electronic Publication: 2022 Nov 12.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*/genetics
Pancreatic Neoplasms*/pathology
Animals ; beta Catenin/metabolism ; Cell Proliferation/genetics ; Cell Movement/genetics ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic
SCR Disease Name:
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł:
R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton.
Autorzy:
Nagano K; School of Dental Medicine, Harvard University, Boston, United States.
Yamana K; School of Dental Medicine, Harvard University, Boston, United States.
Saito H; School of Dental Medicine, Harvard University, Boston, United States.
Kiviranta R; School of Dental Medicine, Harvard University, Boston, United States.
Pedroni AC; School of Dental Medicine, Harvard University, Boston, United States.
Raval D; School of Dental Medicine, Harvard University, Boston, United States.
Niehrs C; German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany.
Gori F; School of Dental Medicine, Harvard University, Boston, United States.
Baron R; School of Dental Medicine, Harvard University, Boston, United States.; Department of Medicine, Harvard Medical School, Boston, United States.; Endocrine Unit, Massachusetts General Hospital, Boston, United States.
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Źródło:
ELife [Elife] 2022 Nov 02; Vol. 11. Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Wnt Signaling Pathway*/physiology
Osteogenesis*
Humans ; Mice ; Animals ; Phosphorylation ; Bone and Bones ; Glycoproteins
Czasopismo naukowe
Tytuł:
Salinomycin alleviates osteoarthritis progression via inhibiting Wnt/β-catenin signaling.
Autorzy:
Chen J; Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China; The First People's Hospital of Zhaoqing, Zhaoqing 526020, China.
Liu J; Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.
Chen S; Guangxi Botanical Garden of Medicinal Plants, Nanning, China; Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Lai R; Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zheng C; Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.
Lu J; Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.
Jiang X; Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.
He F; Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.
Yang C; Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.
Li K; Academy of Orthopedics, Guangdong Province, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Xie K; Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.
Tang Y; Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China. Electronic address: .
Wang L; State Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai, China.
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2022 Nov; Vol. 112, pp. 109225. Date of Electronic Publication: 2022 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
Osteoarthritis*/metabolism
Osteoarthritis*/pathology
Osteophyte*/metabolism
Osteophyte*/pathology
Wnt Signaling Pathway*
Animals ; Mice ; Aggrecans/metabolism ; beta Catenin/metabolism ; Cartilage, Articular/pathology ; Cells, Cultured ; Chondrocytes ; Disease Models, Animal ; Interleukin-1beta/metabolism ; Ionophores/metabolism ; Ionophores/pharmacology ; Ionophores/therapeutic use ; Matrix Metalloproteinase 13/metabolism ; Menisci, Tibial/pathology ; Sclerosis/metabolism ; Sclerosis/pathology ; Thrombospondins/metabolism ; Thrombospondins/pharmacology ; Thrombospondins/therapeutic use
Czasopismo naukowe
Tytuł:
Knockdown of SOX9 alleviates tracheal fibrosis through the Wnt/β-catenin signaling pathway.
Autorzy:
Gu L; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Li A; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Lin J; Department of Infection Disease, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Gan Y; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
He C; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Xiao R; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Liao J; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Li Y; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China. .
Guo S; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China. .
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Źródło:
Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2022 Nov; Vol. 100 (11), pp. 1659-1670. Date of Electronic Publication: 2022 Oct 03.
Typ publikacji:
Journal Article
MeSH Terms:
SOX9 Transcription Factor*/genetics
SOX9 Transcription Factor*/metabolism
Trachea*/pathology
Wnt Signaling Pathway*
Animals ; Rats ; beta Catenin/genetics ; beta Catenin/metabolism ; Cell Proliferation/genetics ; Fibrosis ; Glycogen Synthase Kinase 3 beta/metabolism ; Inflammation/metabolism
Czasopismo naukowe
Tytuł:
FAM96A and FAM96B function as new tumor suppressor genes in breast cancer through regulation of the Wnt/β-catenin signaling pathway.
Autorzy:
Zhang DD; Beijing International Science and Technology Cooperation Base of Antivirus Drug, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, China.
Sun XL; Beijing International Science and Technology Cooperation Base of Antivirus Drug, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, China.
Liang ZY; Beijing International Science and Technology Cooperation Base of Antivirus Drug, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, China.
Wang XY; Beijing International Science and Technology Cooperation Base of Antivirus Drug, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, China.
Zhang LN; Beijing International Science and Technology Cooperation Base of Antivirus Drug, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, China. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2022 Nov 01; Vol. 308, pp. 120983. Date of Electronic Publication: 2022 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/pathology
Wnt Signaling Pathway*/genetics
Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Epithelial-Mesenchymal Transition/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Genes, Tumor Suppressor ; Humans ; Neoplasm Invasiveness/genetics ; beta Catenin/genetics ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł:
The role of the Wnt signalling pathway in the energy metabolism of bone remodelling.
Autorzy:
Zhu M; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Beijing, China.; Research Unit of Tooth Development and Regeneration, Chinese Academy of Medical Sciences, Beijing, China.
Fan Z; Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Beijing, China.; Research Unit of Tooth Development and Regeneration, Chinese Academy of Medical Sciences, Beijing, China.
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Źródło:
Cell proliferation [Cell Prolif] 2022 Nov; Vol. 55 (11), pp. e13309. Date of Electronic Publication: 2022 Jul 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Wnt Signaling Pathway*/physiology
Bone Resorption*/metabolism
Humans ; Bone Remodeling ; Osteogenesis ; Energy Metabolism
Czasopismo naukowe
Tytuł:
Therapeutic approaches to activate the canonical Wnt pathway for bone regeneration.
Autorzy:
Nelson AL; Center for Regenerative and Personalized Medicine, Steadman Philippon Research Institute (SPRI), Vail, Colorado, USA.; School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, USA.
Fontana G; Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Miclau E; Center for Regenerative and Personalized Medicine, Steadman Philippon Research Institute (SPRI), Vail, Colorado, USA.
Rongstad M; Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Murphy W; Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Huard J; Center for Regenerative and Personalized Medicine, Steadman Philippon Research Institute (SPRI), Vail, Colorado, USA.; Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Ehrhart N; School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, USA.; Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Bahney C; Center for Regenerative and Personalized Medicine, Steadman Philippon Research Institute (SPRI), Vail, Colorado, USA.; School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, USA.; Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.; Orthopaedic Trauma Institute, University of California, San Francisco (UCSF), San Francisco, California, USA.
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Źródło:
Journal of tissue engineering and regenerative medicine [J Tissue Eng Regen Med] 2022 Nov; Vol. 16 (11), pp. 961-976. Date of Electronic Publication: 2022 Sep 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Wnt Signaling Pathway*
Bone Regeneration*
Osteogenesis
Czasopismo naukowe
Tytuł:
Wnt/β-catenin signaling activator restores hair regeneration suppressed by diabetes mellitus.
Autorzy:
Ryu YC; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Kim YR; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Park J; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Choi S; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Kim GU; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Kim E; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Hwang Y; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Kim H; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Bak SS; Department of Immunology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Lee JE; Department of Immunology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Sung YK; Department of Immunology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Han G; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Lee SH; CK Regeon Inc., Engineering Research Park, Seoul 03722, Korea.
Choi KY; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722; CK Regeon Inc., Engineering Research Park, Seoul 03722, Korea.
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Źródło:
BMB reports [BMB Rep] 2022 Nov; Vol. 55 (11), pp. 559-564.
Typ publikacji:
Wiadomości
MeSH Terms:
Wnt Signaling Pathway*/physiology
Diabetes Mellitus, Experimental*/metabolism
Humans ; Mice ; Animals ; beta Catenin/metabolism ; Hair/metabolism ; Hair Follicle/metabolism ; Alopecia/metabolism
Periodyk
Tytuł:
Wnt signaling modulator DKK4 inhibits colorectal cancer metastasis through an AKT/Wnt/β-catenin negative feedback pathway.
Autorzy:
Liang J; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.
Sun L; Department of Gastroenterology, The Affiliated Children's Hospital of Xi'an Jiaotong University, Xi'an, China.
Li Y; Department of Endocrinology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Liu W; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China; College of Life Sciences, Northwest University, Xi'an, China.
Li D; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.
Chen P; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China; Department of Gastroenterology, Xingping People's Hospital, Xianyang, China.
Wang X; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China; Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China.
Hui J; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.
Zhou J; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.
Liu H; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.
Cao T; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.
Pang M; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.
Guo M; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.
Wang X; Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China. Electronic address: .
Zhao X; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China. Electronic address: .
Lu Y; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Nov; Vol. 298 (11), pp. 102545. Date of Electronic Publication: 2022 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Wnt Signaling Pathway*
Colorectal Neoplasms*/pathology
Mice ; Animals ; beta Catenin/genetics ; beta Catenin/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Feedback ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Cell Proliferation ; Cell Movement
Czasopismo naukowe

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