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    Wyświetlanie 1-15 z 15
    Tytuł:
    The relationship of mRNA with protein expression in CD8+ T cells associates with gene class and gene characteristics.
    Autorzy:
    Nicolet BP; Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
    Wolkers MC; Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
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    Źródło:
    PloS one [PLoS One] 2022 Oct 19; Vol. 17 (10), pp. e0276294. Date of Electronic Publication: 2022 Oct 19 (Print Publication: 2022).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    AU Rich Elements*
    Lymphocyte Activation*/genetics
    Humans ; RNA, Messenger/metabolism ; 3' Untranslated Regions/genetics ; CD8-Positive T-Lymphocytes/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Sequence determinants as key regulators in gene expression of T cells.
    Autorzy:
    Nicolet BP; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
    Zandhuis ND; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
    Lattanzio VM; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
    Wolkers MC; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
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    Źródło:
    Immunological reviews [Immunol Rev] 2021 Nov; Vol. 304 (1), pp. 10-29. Date of Electronic Publication: 2021 Sep 05.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    MicroRNAs*
    RNA Processing, Post-Transcriptional*
    Gene Expression ; Gene Expression Regulation ; RNA, Messenger/metabolism ; RNA-Binding Proteins/metabolism ; T-Lymphocytes/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.
    Autorzy:
    Pascutti MF; Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
    Geerman S; Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
    Slot E; Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
    van Gisbergen KP; Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
    Boon L; Bioceros BV, Utrecht, The Netherlands.
    Arens R; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
    van Lier RA; Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
    Wolkers MC; Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
    Nolte MA; Sanquin Research, Department of Hematopoiesis, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2015 Mar 04; Vol. 11 (3), pp. e1004675. Date of Electronic Publication: 2015 Mar 04 (Print Publication: 2015).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Immunity, Cellular*
    CD8-Positive T-Lymphocytes/*immunology
    Glucocorticoid-Induced TNFR-Related Protein/*immunology
    Lymphocytic Choriomeningitis/*immunology
    Lymphocytic choriomeningitis virus/*immunology
    T-Lymphocytes, Helper-Inducer/*immunology
    Animals ; CD40 Ligand/genetics ; CD40 Ligand/immunology ; CD8-Positive T-Lymphocytes/pathology ; Chronic Disease ; Glucocorticoid-Induced TNFR-Related Protein/genetics ; Interferon-gamma/genetics ; Interferon-gamma/immunology ; Interleukin-2/genetics ; Interleukin-2/immunology ; Lymphocytic Choriomeningitis/genetics ; Lymphocytic Choriomeningitis/pathology ; Mice ; Mice, Transgenic ; T-Box Domain Proteins/genetics ; T-Box Domain Proteins/immunology ; T-Lymphocytes, Helper-Inducer/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Adrenergic β2 receptor activation stimulates anti-inflammatory properties of dendritic cells in vitro.
    Autorzy:
    Nijhuis LE; Tytgat Institute for Gastro-Intestinal and Liver Research, Academic Medical Center, Amsterdam, The Netherlands.
    Olivier BJ; Tytgat Institute for Gastro-Intestinal and Liver Research, Academic Medical Center, Amsterdam, The Netherlands.
    Dhawan S; Tytgat Institute for Gastro-Intestinal and Liver Research, Academic Medical Center, Amsterdam, The Netherlands.
    Hilbers FW; Tytgat Institute for Gastro-Intestinal and Liver Research, Academic Medical Center, Amsterdam, The Netherlands.
    Boon L; Bioceros B.V., Yalelaan 46, Utrecht, The Netherlands.
    Wolkers MC; Sanquin Research/Landsteiner Laboratory, Department of Hematopoiesis, Amsterdam, The Netherlands.
    Samsom JN; Laboratory of Pediatric Gastroenterology, Erasmus University Medical Center, Rotterdam, The Netherlands.
    de Jonge WJ; Tytgat Institute for Gastro-Intestinal and Liver Research, Academic Medical Center, Amsterdam, The Netherlands.
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    Źródło:
    PloS one [PLoS One] 2014 Jan 22; Vol. 9 (1), pp. e85086. Date of Electronic Publication: 2014 Jan 22 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cytokines/*metabolism
    Dendritic Cells/*metabolism
    Inflammation Mediators/*metabolism
    Receptors, Adrenergic, beta-2/*metabolism
    Adrenergic beta-Agonists/pharmacology ; Albuterol/pharmacology ; Animals ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/metabolism ; Cells, Cultured ; Dendritic Cells/drug effects ; Dextrans/pharmacokinetics ; Endocytosis/drug effects ; Epinephrine/pharmacology ; Female ; Flow Cytometry ; Fluorescein-5-isothiocyanate/analogs & derivatives ; Fluorescein-5-isothiocyanate/pharmacokinetics ; Forkhead Transcription Factors/metabolism ; Interleukin-10/metabolism ; Interleukin-12/metabolism ; Interleukin-23/metabolism ; Interleukin-6/metabolism ; Mice ; Mice, Inbred C57BL ; Receptors, Adrenergic, beta-2/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Selective expansion of merocytic dendritic cells and CD8DCs confers anti-tumour effect of Fms-like tyrosine kinase 3-ligand treatment in vivo.
    Autorzy:
    Hennies CM; Division of Molecular Immunology, Cincinnati Children's Hospital Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.
    Reboulet RA
    Garcia Z
    Nierkens S
    Wolkers MC
    Janssen EM
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    Źródło:
    Clinical and experimental immunology [Clin Exp Immunol] 2011 Mar; Vol. 163 (3), pp. 381-91. Date of Electronic Publication: 2011 Jan 14.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Adjuvants, Immunologic/*therapeutic use
    CD8 Antigens/*metabolism
    Cancer Vaccines/*immunology
    Dendritic Cells/*immunology
    Membrane Proteins/*therapeutic use
    Neoplasms/*therapy
    Adjuvants, Immunologic/pharmacology ; Adoptive Transfer ; Animals ; Antigens, Surface/metabolism ; CD4-Positive T-Lymphocytes/cytology ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Cancer Vaccines/therapeutic use ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cytokines/metabolism ; Dendritic Cells/cytology ; Dendritic Cells/metabolism ; Dendritic Cells/transplantation ; Immunodominant Epitopes/immunology ; Interferon-gamma/metabolism ; Lymphocyte Activation/immunology ; Membrane Proteins/pharmacology ; Mice ; Mice, Inbred BALB C ; Mice, Transgenic ; Natural Killer T-Cells/immunology ; Neoplasms/immunology ; Neoplasms/prevention & control ; Ovalbumin/immunology ; Peptide Fragments/immunology ; Spleen/cytology ; Spleen/immunology ; Survival Analysis ; Vaccination
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells.
    Autorzy:
    Hamilton SE; Department of Laboratory Medicine and Pathology, University of Minnesota Medical Center, Center for Immunology, Minneapolis, Minnesota 55454, USA.
    Wolkers MC
    Schoenberger SP
    Jameson SC
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    Źródło:
    Nature immunology [Nat Immunol] 2006 May; Vol. 7 (5), pp. 475-81. Date of Electronic Publication: 2006 Apr 09.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Cell Proliferation*
    Immunologic Memory*
    CD4-Positive T-Lymphocytes/*immunology
    CD8-Positive T-Lymphocytes/*immunology
    Homeostasis/*immunology
    Adoptive Transfer ; Animals ; Apoptosis Regulatory Proteins/metabolism ; CD4-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/cytology ; Listeriosis/immunology ; Membrane Glycoproteins/metabolism ; Mice ; Mice, Knockout ; TNF-Related Apoptosis-Inducing Ligand ; Tumor Necrosis Factor-alpha/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression.
    Autorzy:
    Bins AD; Department of Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.
    Jorritsma A
    Wolkers MC
    Hung CF
    Wu TC
    Schumacher TN
    Haanen JB
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    Źródło:
    Nature medicine [Nat Med] 2005 Aug; Vol. 11 (8), pp. 899-904. Date of Electronic Publication: 2005 Jun 19.
    Typ publikacji:
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Drug Delivery Systems/*methods
    Immunity, Cellular/*immunology
    Influenza A virus/*immunology
    Vaccination/*methods
    Vaccines, DNA/*administration & dosage
    Vaccines, DNA/*immunology
    Animals ; Antigens, Viral/immunology ; Luciferases ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Immunotherapy through TCR gene transfer.
    Autorzy:
    Kessels HW; Division of Immunology, Department of Experimental Animal Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
    Wolkers MC
    van den Boom MD
    van der Valk MA
    Schumacher TN
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    Źródło:
    Nature immunology [Nat Immunol] 2001 Oct; Vol. 2 (10), pp. 957-61.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genes, T-Cell Receptor alpha*
    Genes, T-Cell Receptor beta*
    Genetic Therapy*
    Immunotherapy, Adoptive*
    Neoplasms, Experimental/*therapy
    T-Lymphocytes, Cytotoxic/*transplantation
    Animals ; Autoimmune Diseases/pathology ; Cell Movement ; Cells, Cultured ; Lymphocyte Activation ; Mice ; Mice, Inbred C57BL ; Orthomyxoviridae Infections/immunology ; T-Lymphocytes, Cytotoxic/immunology ; Transduction, Genetic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-15 z 15

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