Autor: "Wolko D" - OpacWWW

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Tytuł:: Efficacy and safety of long-acting recombinant fusion protein linking factor IX with albumin in haemophilia B patients undergoing surgery.
Autorzy:: Négrier C; Centre Régional de Traitement de l'Hémophilie (CRTH)/Unite d'Hemostase Clinique, Hôpital Cardiologique Louis Pradel, University Lyon I, Lyon, France.
Abdul Karim F; National Blood Centre, Kuala Lumpur, Malaysia.
Lepatan LM; Perpetual Succour Hospital, Cebu City, Philippines.
Lienhart A; Centre Régional de Traitement de l'Hémophilie (CRTH)/Unite d'Hemostase Clinique, Hôpital Cardiologique Louis Pradel, University Lyon I, Lyon, France.
López-Fernández MF; Complexo Hospitalario Universitario A Coruňa, A Coruňa, Spain.
Mahlangu J; Haemophilia Clinic, Comprehensive Care Centre Charlotte Maxeke Johannesburg Academic Hospital and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; NHLS South Africa, Johannesburg, South Africa.
Pabinger I; Clinical Division of Haematology and Haemostaseology, Medical Clinic I, Medical University Vienna, Vienna, Austria.
Li Y; Clinical Research and Development, CSL Behring, King of Prussia, PA, USA.
Wolko D; Clinical Research and Development, CSL Behring, King of Prussia, PA, USA.
Voigt C; Clinical Research and Development, CSL Behring, King of Prussia, PA, USA.
Jacobs I; Clinical Research and Development, CSL Behring, King of Prussia, PA, USA.
Santagostino E; A. Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Ca' Granda Foundation, Maggiore Hospital Policlinico, Milan, Italy.; Pokaż więcej
Źródło:: Haemophilia : the official journal of the World Federation of Hemophilia [Haemophilia] 2016 Jul; Vol. 22 (4), pp. e259-66. Date of Electronic Publication: 2016 Jun 22.
Typ publikacji:: Clinical Trial, Phase III; Journal Article; Multicenter Study
MeSH Terms:: Coagulants/*therapeutic use
Factor IX/*therapeutic use
Hemophilia B/*drug therapy
Serum Albumin/*genetics
Adolescent ; Adult ; Child ; Factor IX/genetics ; Factor IX/metabolism ; Half-Life ; Hemophilia B/pathology ; Hemorrhage/prevention & control ; Humans ; Middle Aged ; Postoperative Period ; Preoperative Care ; Recombinant Fusion Proteins/biosynthesis ; Recombinant Fusion Proteins/pharmacokinetics ; Recombinant Fusion Proteins/therapeutic use ; Serum Albumin/metabolism ; Severity of Illness Index ; Surgical Procedures, Operative ; Young Adult

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