Anti-HBc: a significant host predictor of spontaneous HBsAg seroclearance in chronic hepatitis B patients - a retrospective longitudinal study.
Autorzy:
Kan K; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. WongDK; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. Hui RW; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China. Seto WK; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. Yuen MF; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China. .; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. . Mak LY; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China. .; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. .
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BMC gastroenterology [BMC Gastroenterol] 2023 Oct 06; Vol. 23 (1), pp. 348. Date of Electronic Publication: 2023 Oct 06.
A prospective cohort study of renal function and bone turnover in adults with hepatitis B virus (HBV)-HIV co-infection with high prevalence of tenofovir-based antiretroviral therapy use.
Autorzy:
Gizaw A; Virginia Commonwealth University, Richmond, Virginia, USA. King WC; University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA. Hinerman AS; University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA. Chung RT; Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. Lisker-Melman M; Washington University School of Medicine and John Cochran VA Medical Center, St. Louis, Missouri, USA. Ghany MG; National Institute of Health, Bethesda, Maryland, USA. Khalili M; University of California San Francisco, San Francisco, California, USA. Jain MK; University of Texas Southwestern and Parkland Health & Hospital System, Dallas, Texas, USA. Graham J; Biobehavioral Research Lab, Virginia Commonwealth University School of Nursing. Swift-Scanlan T; Biobehavioral Research Lab, Virginia Commonwealth University School of Nursing. Kleiner DE; National Cancer Institute, Bethesda, Maryland, USA. Sulkowski M; Johns Hopkins University, Baltimore, Maryland, USA. WongDK; University Health Network, Toronto, Ontario, Canada. Sterling RK; Virginia Commonwealth University, Richmond, Virginia, USA.
Clinical Outcomes and Quantitative HBV Surface Antigen Levels in Diverse Chronic Hepatitis B Patients in Canada: A Retrospective Real-World Study of CHB in Canada (REVEAL-CANADA).
Autorzy:
Coffin CS; Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada. Haylock-Jacobs S; Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada. Doucette K; Department of Medicine, University of Alberta, Edmonton, AB T6G 2R3, Canada. Ramji A; Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. Ko HH; Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. WongDK; Department of Medicine, University of Toronto, Toronto, ON M5G 2CV, Canada. Elkhashab M; Toronto Liver Centre, Toronto, ON M6H 3M1, Canada. Bailey R; Bailey Health Clinic, Edmonton, AB T5H 4B9, Canada. Uhanova J; Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3T 2N2, Canada. Minuk G; Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3T 2N2, Canada. Tsoi K; Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada. Wong A; Department of Medicine, University of Saskatchewan, Regina, SK S7N 5A2, Canada. Ma MM; Department of Medicine, University of Alberta, Edmonton, AB T6G 2R3, Canada. Tam E; Pacific Gastroenterology Associates, Vancouver, BC V6Z 2K5, Canada. Brahmania M; Multi Organ Transplant Unit, Department of Medicine, Division of Gastroenterology, Western University, London, ON N6A 3K7, Canada. Nudo C; Cité-de-la-Santé de Laval, Laval, QC H7M 3L9, Canada. Zhu J; Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4R2, Canada. Lowe CF; Division of Medical Microbiology, Providence Health Care, Vancouver, BC V6Z 1Y6, Canada. Osiowy C; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada. Lethebe BC; Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada. Congly SE; Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada. Chan EKH; Janssen Global Services LC, Raritan, NJ 08869, USA. Villasis-Keever A; Janssen Global Services LC, Raritan, NJ 08869, USA. Sbarigia U; Janssen Pharmaceuticals NV, 2340 Beerse, Belgium. Cooper CL; Department of Medicine, Division of infectious Diseases, University of Ottawa, Ottawa, ON K1N 6N5, Canada. Fung S; Department of Medicine, University of Toronto, Toronto, ON M5G 2CV, Canada.
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Viruses [Viruses] 2022 Nov 29; Vol. 14 (12). Date of Electronic Publication: 2022 Nov 29.
Early virologic relapse predicts alanine aminotransferase flares after nucleos(t)ide analogue withdrawal in patients with chronic hepatitis B.
Autorzy:
Liem KS; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada.; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands. Chi H; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands. Fung S; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada. WongDK; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada. Yim C; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada. Noureldin S; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada. Chen J; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada. de Man RA; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands. Sarowar A; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada. Feld JJ; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada.; McLaughlin-Rotman Centre for Global Health, Toronto, Ontario, Canada. Hansen BE; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada.; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada. Hou J; Department of Infectious Diseases, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University, Guangzhou, China. Peng J; Department of Infectious Diseases, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University, Guangzhou, China. Janssen HLA; Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada.; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
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Źródło:
Journal of viral hepatitis [J Viral Hepat] 2022 Nov; Vol. 29 (11), pp. 986-993. Date of Electronic Publication: 2022 Sep 14.
Correction: CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma.
Autorzy:
Mitsui Y; Department of Urology Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, 693-8501, Japan. .; Department of Urology, San Francisco Veterans Affairs Medical Center and University of California San Francisco, Bldg 42 Rm 109, San Francisco, CA, 94121, USA. . Chang I; Department of Oral Biology, Yonsei University College of Density, Seoul, South Korea.; Department of Urology, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan. Fukuhara S; Department of Urology, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan. Hiraki M; Department of Urology Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, 693-8501, Japan. Arichi N; Department of Urology Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, 693-8501, Japan. Yasumoto H; Department of Urology Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, 693-8501, Japan. Hirata H; Department of Urology, San Francisco Veterans Affairs Medical Center and University of California San Francisco, Bldg 42 Rm 109, San Francisco, CA, 94121, USA. Yamamura S; Department of Urology, San Francisco Veterans Affairs Medical Center and University of California San Francisco, Bldg 42 Rm 109, San Francisco, CA, 94121, USA. Shahryari V; Department of Urology, San Francisco Veterans Affairs Medical Center and University of California San Francisco, Bldg 42 Rm 109, San Francisco, CA, 94121, USA. Deng G; Department of Urology, San Francisco Veterans Affairs Medical Center and University of California San Francisco, Bldg 42 Rm 109, San Francisco, CA, 94121, USA. WongDK; Department of Urology, San Francisco Veterans Affairs Medical Center and University of California San Francisco, Bldg 42 Rm 109, San Francisco, CA, 94121, USA. Majid S; Department of Urology, San Francisco Veterans Affairs Medical Center and University of California San Francisco, Bldg 42 Rm 109, San Francisco, CA, 94121, USA. Shiina H; Department of Urology Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, 693-8501, Japan. Dahiya R; Department of Urology, San Francisco Veterans Affairs Medical Center and University of California San Francisco, Bldg 42 Rm 109, San Francisco, CA, 94121, USA. Tanaka Y; Department of Urology, San Francisco Veterans Affairs Medical Center and University of California San Francisco, Bldg 42 Rm 109, San Francisco, CA, 94121, USA. .
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BMC cancer [BMC Cancer] 2022 Jul 25; Vol. 22 (1), pp. 813. Date of Electronic Publication: 2022 Jul 25.
Sparse logistic regression revealed the associations between HBV PreS quasispecies and hepatocellular carcinoma.
Autorzy:
Jia JA; Department of Laboratory Medicine, Eastern Hepatobiliary Surgery Hospital, Navy Military Medical University, Shanghai, 200438, China.; Department of Laboratory Medicine, The 901th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Hefei, 230031, China. Zhang S; Centre for Computational Systems Biology, School of Mathematical Sciences, Fudan University, Shanghai, 200433, China. Bai X; Molecular and Computational Program, Department of Biological Sciences, University of Southern California, 1050 Childs Way, Los Angeles, 90089, USA. Fang M; Department of Laboratory Medicine, Eastern Hepatobiliary Surgery Hospital, Navy Military Medical University, Shanghai, 200438, China. Chen S; Department of Laboratory Medicine, Eastern Hepatobiliary Surgery Hospital, Navy Military Medical University, Shanghai, 200438, China. Liang X; Department of Computer Science, Fudan University, Shanghai, 200433, China. Zhu S; Department of Computer Science, Fudan University, Shanghai, 200433, China.; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, 200433, China. WongDK; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong SAR, China. Zhang A; Department of Medicine, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518033, China. Feng J; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, 200433, China.; Department of Computer Science, University of Warwick, Coventry, CV4 7AL, UK. Sun F; Molecular and Computational Program, Department of Biological Sciences, University of Southern California, 1050 Childs Way, Los Angeles, 90089, USA. . Gao C; Department of Laboratory Medicine, Eastern Hepatobiliary Surgery Hospital, Navy Military Medical University, Shanghai, 200438, China. .; Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. .
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Źródło:
Virology journal [Virol J] 2022 Jun 28; Vol. 19 (1), pp. 114. Date of Electronic Publication: 2022 Jun 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
First-line oral antiviral therapies showed similar efficacies in suppression of serum HBcrAg in chronic hepatitis B patients.
Autorzy:
Mak LY; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road 102,, Pok Fu Lam, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Pok Fu Lam, Hong Kong. WongDK; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road 102,, Pok Fu Lam, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Pok Fu Lam, Hong Kong. Cheung KS; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road 102,, Pok Fu Lam, Hong Kong.; Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. Seto WK; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road 102,, Pok Fu Lam, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Pok Fu Lam, Hong Kong. Fung J; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road 102,, Pok Fu Lam, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Pok Fu Lam, Hong Kong. Yuen MF; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road 102,, Pok Fu Lam, Hong Kong. .; State Key Laboratory of Liver Research, The University of Hong Kong, Pok Fu Lam, Hong Kong. .
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BMC gastroenterology [BMC Gastroenterol] 2021 Mar 17; Vol. 21 (1), pp. 123. Date of Electronic Publication: 2021 Mar 17.
Maintained virological suppression and renal function with reduced dose tenofovir disoproxil fumarate in renally impaired chronic hepatitis B patients.
Autorzy:
Liem KS; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, ON, Canada.; Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands. WongDK; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, ON, Canada. Fung S; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, ON, Canada. Zahirieh A; Sunnybrook Health Sciences Centre, Toronto, ON, Canada. Yim C; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, ON, Canada. Zanjir WR; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, ON, Canada. Feld JJ; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, ON, Canada.; McLaughlin-Rotman Centre for Global Health, Toronto, ON, Canada. Hansen BE; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, ON, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada. Janssen HLA; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
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Journal of viral hepatitis [J Viral Hepat] 2021 Jan; Vol. 28 (1), pp. 51-60. Date of Electronic Publication: 2020 Oct 04.
Entecavir Reduced Serum Hepatitis B Core-Related Antigen in Chronic Hepatitis B Patients with Hepatocellular Carcinoma.
Autorzy:
Mak LY; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, China. Ko KL; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, China. To WP; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, China. WongDK; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. Seto WK; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China.; Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. Fung J; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. Yuen MF; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China.
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Źródło:
Gut and liver [Gut Liver] 2020 Sep 15; Vol. 14 (5), pp. 665-668.
Optimized ex vivo stimulation identifies multi-functional HBV-specific T cells in a majority of chronic hepatitis B patients.
Autorzy:
Chua CG; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.; Institute of Medical Sciences, University of Toronto, Toronto, Canada. Mehrotra A; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada. Mazzulli T; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Department of Microbiology, Mount Sinai Hospital, University Health Network, Toronto, Canada. WongDK; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada. Feld JJ; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada. Janssen HLA; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada. Gehring AJ; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada. .; Institute of Medical Sciences, University of Toronto, Toronto, Canada. .
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Scientific reports [Sci Rep] 2020 Jul 09; Vol. 10 (1), pp. 11344. Date of Electronic Publication: 2020 Jul 09.
Hepatitis B core-related antigen levels after HBeAg seroconversion is associated with the development of hepatocellular carcinoma.
Autorzy:
To WP; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China. Mak LY; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China. WongDK; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, China. Fung J; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, China. Liu F; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China. Seto WK; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, China.; Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China. Lai CL; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, China. Yuen MF; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, China.
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Journal of viral hepatitis [J Viral Hepat] 2019 Dec; Vol. 26 (12), pp. 1473-1480. Date of Electronic Publication: 2019 Sep 02.
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