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    Tytuł:
    TLR4 deficiency upregulates TLR9 expression and enhances irinotecan-related intestinal mucositis and late-onset diarrhoea.
    Autorzy:
    Wong DVT; Graduate Program in Pathology, Department of Pathology and Forensic Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.; Laboratory of Molecular Biology and Genetics, Haroldo Juaçaba Hospital, Cancer Institute of Ceará (ICC), Fortaleza, Ceará, Brazil.
    Holanda RBF; Graduate Program in Pharmaceutical Sciences, Department of Pharmacy, Faculty of Pharmacy, Nursing and Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Cajado AG; Laboratory of Inflammation and Cancer Pharmacology, Drug Research and Development Center (NPDM), Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Bandeira AM; Laboratory of Inflammation and Cancer Pharmacology, Drug Research and Development Center (NPDM), Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Pereira JFB; Laboratory of Inflammation and Cancer Pharmacology, Drug Research and Development Center (NPDM), Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Amorim JO; Laboratory of Molecular Biology and Genetics, Haroldo Juaçaba Hospital, Cancer Institute of Ceará (ICC), Fortaleza, Ceará, Brazil.
    Torres CS; Laboratory of Inflammation and Cancer Pharmacology, Drug Research and Development Center (NPDM), Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Ferreira LMM; Laboratory of Inflammation and Cancer Pharmacology, Drug Research and Development Center (NPDM), Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Lopes MHS; Graduate Program in Pathology, Department of Pathology and Forensic Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Oliveira RTG; Cancer Cytogenomic Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Pereira AF; Laboratory of Inflammation and Cancer Pharmacology, Drug Research and Development Center (NPDM), Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Sant'Ana RO; Laboratory of Molecular Biology and Genetics, Haroldo Juaçaba Hospital, Cancer Institute of Ceará (ICC), Fortaleza, Ceará, Brazil.; Clinical Oncology Service, Haroldo Juaçaba Hospital, Cancer Institute of Ceará (ICC), Fortaleza, Ceará, Brazil.
    Arruda LM; Clinical Oncology Service, Haroldo Juaçaba Hospital, Cancer Institute of Ceará (ICC), Fortaleza, Ceará, Brazil.
    Ribeiro-Júnior HL; Cancer Cytogenomic Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Pinheiro RF; Cancer Cytogenomic Laboratory, Drug Research and Development Center (NPDM), Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Almeida PRC; Graduate Program in Pathology, Department of Pathology and Forensic Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Carvalho RF; Department of Structural and Functional Biology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
    Chaves FF; Clinical Oncology Service, Haroldo Juaçaba Hospital, Cancer Institute of Ceará (ICC), Fortaleza, Ceará, Brazil.
    Rocha-Filho DR; Clinical Oncology Service, Walter Cantídio University Hospital, Federal University of Ceará, Fortaleza, Ceará, Brazil.
    Cunha FQ; Department of Pharmacology, School of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, State of São Paulo, Brazil.
    Lima-Júnior RCP; Laboratory of Inflammation and Cancer Pharmacology, Drug Research and Development Center (NPDM), Department of Physiology and Pharmacology, Federal University of Ceará, Fortaleza, Ceará, Brazil.
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    Źródło:
    British journal of pharmacology [Br J Pharmacol] 2021 Oct; Vol. 178 (20), pp. 4193-4209. Date of Electronic Publication: 2021 Aug 01.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Diarrhea*/chemically induced
    Diarrhea*/genetics
    Irinotecan*/toxicity
    Mucositis*/chemically induced
    Mucositis*/genetics
    Toll-Like Receptor 4*/genetics
    Toll-Like Receptor 9*/genetics
    Animals ; Humans ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Circulating let-7e-5p, miR-106a-5p, miR-28-3p, and miR-542-5p as a Promising microRNA Signature for the Detection of Colorectal Cancer.
    Autorzy:
    Silva CMS; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza 60430-270, Brazil.
    Barros-Filho MC; International Research Center-CIPE, A.C. Camargo Cancer Center, Sao Paulo 01525-001, Brazil.; Department of Head and Neck Surgery, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo/LIM-28-São Paulo, Sao Paulo 05403-000, Brazil.
    Wong DVT; Department of Pathology and Forensic Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza 60430-160, Brazil.; Haroldo Juaçaba Hospital-Cancer Institute of Ceará, Fortaleza 60430-230, Brazil.
    Mello JBH; Molecular Carcinogenesis Program, Brazilian National Cancer Institute (INCA), Rio de Janeiro 20230-240, Brazil.
    Nobre LMS; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza 60430-270, Brazil.
    Wanderley CWS; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza 60430-270, Brazil.
    Lucetti LT; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza 60430-270, Brazil.
    Muniz HA; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza 60430-270, Brazil.
    Paiva IKD; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza 60430-270, Brazil.
    Kuasne H; International Research Center-CIPE, A.C. Camargo Cancer Center, Sao Paulo 01525-001, Brazil.
    Ferreira DPP; Cesar Cals Hospital, Fortaleza 60015-152, Brazil.
    Cunha MPSS; Haroldo Juaçaba Hospital-Cancer Institute of Ceará, Fortaleza 60430-230, Brazil.
    Hirth CG; Haroldo Juaçaba Hospital-Cancer Institute of Ceará, Fortaleza 60430-230, Brazil.
    Silva PGB; Haroldo Juaçaba Hospital-Cancer Institute of Ceará, Fortaleza 60430-230, Brazil.
    Sant'Ana RO; Haroldo Juaçaba Hospital-Cancer Institute of Ceará, Fortaleza 60430-230, Brazil.; School of Medicine, University of Fortaleza, Fortaleza 60811-905, Brazil.
    Souza MHLP; Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza 60430-160, Brazil.
    Quetz JS; Haroldo Juaçaba Hospital-Cancer Institute of Ceará, Fortaleza 60430-230, Brazil.
    Rogatto SR; Department of Clinical Genetics, University Hospital of Southern Denmark, 7100 Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, 5000 Odense, Denmark.; Danish Colorectal Cancer Center South, 7100 Vejle, Denmark.
    Lima-Junior RCP; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza 60430-270, Brazil.
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    Źródło:
    Cancers [Cancers (Basel)] 2021 Mar 24; Vol. 13 (7). Date of Electronic Publication: 2021 Mar 24.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Interleukin-18 (IL-18) is equally expressed in inflammatory breast cancer and noninflammatory locally advanced breast cancer: A possible association with chemotherapy response.
    Autorzy:
    Aguiar MAN; Department of Surgery, Faculty of Medicine, Federal University of Ceará, Brazil.
    Wanderley CWS; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Brazil.
    Nobre LMS; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Brazil.
    Alencar MRM; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Brazil.
    Saldanha MDPS; Cancer Institute of Ceará, Brazil.
    Souza AM; Department of Pathology and Forensic Medicine, Faculty of Medicine, Federal University of Ceará, Brazil.
    Wong DVT; Department of Pathology and Forensic Medicine, Faculty of Medicine, Federal University of Ceará, Brazil.
    Barros PG; Cancer Institute of Ceará, Brazil.; Department of Dentistry, University Center Christus.
    Almeida PRC; Department of Pathology and Forensic Medicine, Faculty of Medicine, Federal University of Ceará, Brazil.
    Lima-Júnior RCP; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Brazil.
    Ribeiro RA; Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Brazil.; Cancer Institute of Ceará, Brazil.
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    Źródło:
    Asia-Pacific journal of clinical oncology [Asia Pac J Clin Oncol] 2018 Apr; Vol. 14 (2), pp. e138-e144. Date of Electronic Publication: 2017 Aug 02.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Inflammatory Breast Neoplasms/*genetics
    Interleukin-18/*metabolism
    Adult ; Aged ; Female ; Humans ; Inflammatory Breast Neoplasms/drug therapy ; Inflammatory Breast Neoplasms/mortality ; Middle Aged ; Prognosis ; Retrospective Studies ; Survival Analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-5 z 5

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