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Tytuł :
Identification of an ATP metabolism-related signature associated with prognosis and immune microenvironment in gliomas.
Autorzy :
Huang R; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Li G; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Wang Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Hu H; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Zeng F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Zhang K; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Wang K; Chinese Glioma Cooperative Group (CGCG), Beijing, China.; Department of Gamma Knife Center, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Jul; Vol. 111 (7), pp. 2325-2335. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor*
Metabolome*
Adenosine Triphosphate/*metabolism
Glioma/*etiology
Glioma/*metabolism
Tumor Microenvironment/*immunology
Adult ; Computational Biology/methods ; DNA Methylation ; Gene Expression Regulation, Neoplastic ; Glioma/mortality ; Glioma/pathology ; Humans ; Metabolomics/methods ; Middle Aged ; Molecular Sequence Annotation ; Neoplasm Grading ; Prognosis ; Promoter Regions, Genetic ; ROC Curve ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł :
Molecular subtyping reveals immune alterations in IDH wild-type lower-grade diffuse glioma.
Autorzy :
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, PR China.
Li GZ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.
Liu HJ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.
Zhao Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, PR China.
Chai RC; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, PR China.
Liu YQ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, PR China.
Jiang HY; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.
Zhai Y; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.
Feng YM; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.
Li RP; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.
Zhang W; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, PR China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, PR China.
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Źródło :
The Journal of pathology [J Pathol] 2020 Jul; Vol. 251 (3), pp. 272-283. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Transcriptome*
Biomarkers, Tumor/*genetics
Brain Neoplasms/*genetics
Glioma/*genetics
Isocitrate Dehydrogenase/*genetics
Brain Neoplasms/classification ; Brain Neoplasms/enzymology ; Brain Neoplasms/immunology ; Cluster Analysis ; Female ; Gene Expression Profiling ; Genetic Predisposition to Disease ; Glioma/classification ; Glioma/enzymology ; Glioma/immunology ; Humans ; Male ; Neoplasm Grading ; Phenotype ; Predictive Value of Tests ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
EFEMP2 indicates assembly of M0 macrophage and more malignant phenotypes of glioma.
Autorzy :
Huang L; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Wang Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Chang Y; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Wang K; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Kang X; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Huang R; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Zhang Y; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Chen J; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Zeng F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Zhao Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Li G; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Huang H; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Jiang T; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Hu H; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
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Źródło :
Aging [Aging (Albany NY)] 2020 May 12; Vol. 12 (9), pp. 8397-8412. Date of Electronic Publication: 2020 May 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Neoplasms/*pathology
Extracellular Matrix Proteins/*metabolism
Glioma/*pathology
Macrophages/*pathology
Brain Neoplasms/metabolism ; Cell Differentiation ; Cell Line, Tumor ; Cell Proliferation ; Glioma/metabolism ; Humans ; Macrophages/metabolism ; Phenotype ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Prognostic power of a lipid metabolism gene panel for diffuse gliomas.
Autorzy :
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, China.
Zhao Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, China.
Chai RC; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, China.
Liu YQ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, China.
Li GZ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, China.
Jiang HY; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, China.
Jiang T; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Nov; Vol. 23 (11), pp. 7741-7748. Date of Electronic Publication: 2019 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, Neoplasm*
Brain Neoplasms/*genetics
Glioma/*genetics
Lipid Metabolism/*genetics
Brain Neoplasms/immunology ; Brain Neoplasms/pathology ; Cell Division ; Cohort Studies ; Female ; Glioma/immunology ; Glioma/pathology ; Humans ; Male ; Multivariate Analysis ; Neoplasm Grading ; Phenotype ; Prognosis ; Proportional Hazards Models ; Risk Factors
Czasopismo naukowe
Tytuł :
Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma.
Autorzy :
Chai RC; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.; China National Clinical Research Center for Neurological Diseases.
Zhang KN; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Chang YZ; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Liu YQ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Zhao Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Wang KY; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Chang YH; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Jiang T; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.; China National Clinical Research Center for Neurological Diseases.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wang YZ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.; China National Clinical Research Center for Neurological Diseases.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
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Źródło :
Carcinogenesis [Carcinogenesis] 2019 Oct 16; Vol. 40 (10), pp. 1229-1239.
Typ publikacji :
Journal Article
MeSH Terms :
Chromosome Deletion*
Gene Expression Regulation, Neoplastic*
Mutation*
Biomarkers, Tumor/*genetics
Brain Neoplasms/*pathology
Chromosomes, Human, Pair 19/*genetics
Glioma/*pathology
Adult ; Aged ; Aged, 80 and over ; Apoptosis ; Brain Neoplasms/genetics ; Brain Neoplasms/surgery ; Cell Movement ; Cell Proliferation ; Follow-Up Studies ; Glioma/genetics ; Glioma/surgery ; Humans ; Middle Aged ; Prognosis ; RNA-Seq ; Survival Rate ; Transcriptome ; Tumor Cells, Cultured ; Young Adult
Czasopismo naukowe
Tytuł :
PTB-AS, a Novel Natural Antisense Transcript, Promotes Glioma Progression by Improving PTBP1 mRNA Stability with SND1.
Autorzy :
Zhu L; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Wei Q; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Qi Y; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Ruan X; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Wu F; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Li L; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Zhou J; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Liu W; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Jiang T; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing China.
Zhang J; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Yin B; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Yuan J; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Qiang B; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
Han W; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China. Electronic address: .
Peng X; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China; Institute of Medical Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Kunming, China. Electronic address: .
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Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2019 Sep 04; Vol. 27 (9), pp. 1621-1637. Date of Electronic Publication: 2019 Jun 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Stability*
Endonucleases/*metabolism
Glioma/*genetics
Heterogeneous-Nuclear Ribonucleoproteins/*genetics
Polypyrimidine Tract-Binding Protein/*genetics
RNA, Antisense/*genetics
RNA, Messenger/*genetics
3' Untranslated Regions ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; MicroRNAs/genetics ; RNA Interference ; RNA, Long Noncoding/genetics ; RNA-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
RNA processing genes characterize RNA splicing and further stratify lower-grade glioma.
Autorzy :
Chai RC; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.; China National Clinical Research Center for Neurological Diseases and.
Li YM; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang KN; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Chang YZ; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Liu YQ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Zhao Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Wang ZL; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Chang YH; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Li GZ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Wang KY; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Wang YZ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.; China National Clinical Research Center for Neurological Diseases and.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
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Źródło :
JCI insight [JCI Insight] 2019 Aug 13; Vol. 5. Date of Electronic Publication: 2019 Aug 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Transcriptome*
Glioma/*genetics
RNA Splicing/*genetics
Adenosine Triphosphatases/genetics ; Base Sequence ; Cell Line, Tumor ; Computational Biology ; DNA-Binding Proteins/genetics ; Gene Expression Profiling ; Glioma/metabolism ; Glioma/mortality ; Humans ; Kaplan-Meier Estimate ; Molecular Biology ; Multivariate Analysis ; Prognosis ; RNA Splicing/physiology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Regression Analysis ; Survival Analysis ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
The antibiotic clofoctol suppresses glioma stem cell proliferation by activating KLF13.
Autorzy :
Hu Y; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Zhang M; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Tian N; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Li D; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Hu P; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Wang Z; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Wang L; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Hao W; National Experimental Demonstration Center of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Kang J; National Experimental Demonstration Center of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yin B; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Zheng Z; Centralab Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Jiang T; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yuan J; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Qiang B; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Han W; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Peng X; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.; Institute of Medical Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Kunming, China.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2019 May 21; Vol. 129 (8), pp. 3072-3085. Date of Electronic Publication: 2019 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibiotics, Antineoplastic/*pharmacology
Cell Proliferation/*drug effects
Glioma/*drug therapy
Neoplastic Stem Cells/*metabolism
Animals ; Cell Cycle Proteins/metabolism ; Cell Line, Tumor ; Cresols/pharmacology ; DNA-Binding Proteins/metabolism ; Glioma/metabolism ; Glioma/pathology ; Humans ; Kruppel-Like Transcription Factors/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Proteins/metabolism ; Neoplastic Stem Cells/pathology ; RNA-Binding Proteins/metabolism ; Repressor Proteins/metabolism ; Xenograft Model Antitumor Assays ; Zebrafish
Czasopismo naukowe
Tytuł :
FHL3 links cell growth and self-renewal by modulating SOX4 in glioma.
Autorzy :
Han W; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Hu P; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Wu F; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, 100050, Beijing, China.
Wang S; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Hu Y; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Li S; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Jiang T; Department of Neurosurgery, Beijing Tiantan Hospital, 100050, Beijing, China.
Qiang B; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China. .
Peng X; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China. .; Institute of Medical Biology, Chinese Academy of Medical Sciences, Chinese Academy of Medical Science and Peking Union Medical College, 650118, Kunming, China. .
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Źródło :
Cell death and differentiation [Cell Death Differ] 2019 May; Vol. 26 (5), pp. 796-811. Date of Electronic Publication: 2018 Jun 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glioma/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
LIM Domain Proteins/*genetics
SOXB1 Transcription Factors/*genetics
SOXC Transcription Factors/*genetics
Animals ; Cell Proliferation/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Glioma/pathology ; Humans ; Male ; Mice ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Protein Phosphatase 2C/genetics ; Smad2 Protein/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Elevated signature of a gene module coexpressed with CDC20 marks genomic instability in glioma.
Autorzy :
Zhang Y; Beijing Key Laboratory of Gene Resource and Molecular Development, Laboratory of Neuroscience and Brain Development, Beijing Normal University, 100875 Beijing, China.
Li J; Beijing Key Laboratory of Gene Resource and Molecular Development, Laboratory of Neuroscience and Brain Development, Beijing Normal University, 100875 Beijing, China.
Yi K; Laboratory of Neuro-Oncology, Tianjin Neurological Institute, Department of Neurosurgery, Tianjin Medical University General Hospital, 300052 Tianjin, China.; Key Laboratory of Neurotrauma, Variation, and Regeneration, Ministry of Education and Tianjin Municipal Government, 300052 Tianjin, China.
Feng J; Beijing Key Laboratory of Gene Resource and Molecular Development, Laboratory of Neuroscience and Brain Development, Beijing Normal University, 100875 Beijing, China.
Cong Z; Beijing Key Laboratory of Gene Resource and Molecular Development, Laboratory of Neuroscience and Brain Development, Beijing Normal University, 100875 Beijing, China.
Wang Z; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 100070 Beijing, China.; Beijing Neurosurgical Institute, 100070 Beijing, China.
Wei Y; Beijing Key Laboratory of Gene Resource and Molecular Development, Laboratory of Neuroscience and Brain Development, Beijing Normal University, 100875 Beijing, China.
Wu F; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 100070 Beijing, China.; Beijing Neurosurgical Institute, 100070 Beijing, China.
Cheng W; Department of Neurosurgery, The First Hospital of China Medical University, 110001 Shenyang, China.
Samo AA; Beijing Key Laboratory of Gene Resource and Molecular Development, Laboratory of Neuroscience and Brain Development, Beijing Normal University, 100875 Beijing, China.
Salomoni P; Nuclear Function Group, German Center for Neurodegenerative Diseases, 53127 Bonn, Germany.
Yang Q; Beijing Key Laboratory of Gene Resource and Molecular Development, Laboratory of Neuroscience and Brain Development, Beijing Normal University, 100875 Beijing, China.
Huang Y; Department of Medical Genetics, School of Basic Medical Sciences, Peking University Health Science Center, 100191 Beijing, China.
Kang C; Laboratory of Neuro-Oncology, Tianjin Neurological Institute, Department of Neurosurgery, Tianjin Medical University General Hospital, 300052 Tianjin, China; .; Key Laboratory of Neurotrauma, Variation, and Regeneration, Ministry of Education and Tianjin Municipal Government, 300052 Tianjin, China.; Chinese Glioma Genome Atlas Network and Asian Glioma Genome Atlas Network, Fengtai District, 100070 Beijing, China.
Jiang T; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 100070 Beijing, China; .; Beijing Neurosurgical Institute, 100070 Beijing, China.; Chinese Glioma Genome Atlas Network and Asian Glioma Genome Atlas Network, Fengtai District, 100070 Beijing, China.
Fan X; Beijing Key Laboratory of Gene Resource and Molecular Development, Laboratory of Neuroscience and Brain Development, Beijing Normal University, 100875 Beijing, China; .; Chinese Glioma Genome Atlas Network and Asian Glioma Genome Atlas Network, Fengtai District, 100070 Beijing, China.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Apr 02; Vol. 116 (14), pp. 6975-6984. Date of Electronic Publication: 2019 Mar 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Genomic Instability*
Biomarkers, Tumor/*biosynthesis
Cdc20 Proteins/*biosynthesis
Glioma/*metabolism
Neoplasm Proteins/*biosynthesis
Animals ; Biomarkers, Tumor/genetics ; Cdc20 Proteins/genetics ; Chemotherapy, Adjuvant ; Female ; Gene Expression Profiling ; Glioma/drug therapy ; Glioma/genetics ; Glioma/pathology ; Humans ; Male ; Mice ; Mice, Nude ; Neoplasm Proteins/genetics ; Temozolomide/pharmacology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Combinations of four or more CpGs methylation present equivalent predictive value for MGMT expression and temozolomide therapeutic prognosis in gliomas.
Autorzy :
Chai RC; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas (CGGA), Beijing, China.
Zhang KN; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas (CGGA), Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Liu YQ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas (CGGA), Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas (CGGA), Beijing, China.
Zhao Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas (CGGA), Beijing, China.
Wang KY; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas (CGGA), Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jiang T; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas (CGGA), Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wang YZ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas (CGGA), Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
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Źródło :
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2019 Mar; Vol. 25 (3), pp. 314-322. Date of Electronic Publication: 2018 Aug 16.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
CpG Islands*
Antineoplastic Agents, Alkylating/*therapeutic use
Brain Neoplasms/*metabolism
DNA Modification Methylases/*metabolism
DNA Repair Enzymes/*metabolism
Glioma/*metabolism
Temozolomide/*therapeutic use
Tumor Suppressor Proteins/*metabolism
Adult ; Aged ; Biomarkers, Tumor ; Brain Neoplasms/genetics ; Brain Neoplasms/therapy ; Cohort Studies ; DNA Methylation ; DNA Modification Methylases/genetics ; DNA Repair Enzymes/genetics ; Female ; Gene Expression ; Glioma/genetics ; Glioma/therapy ; Humans ; Male ; Middle Aged ; Prognosis ; Promoter Regions, Genetic ; RNA, Messenger/metabolism ; Tumor Suppressor Proteins/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
m A RNA methylation regulators contribute to malignant progression and have clinical prognostic impact in gliomas.
Autorzy :
Chai RC; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100160, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA).
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100160, China.; Chinese Glioma Genome Atlas Network (CGGA).
Wang QX; Laboratory of Neuro-Oncology, Tianjin Neurological Institute, Department of Neurosurgery, Tianjin Medical University General Hospital and Key Laboratory of Neurotrauma, Variation, and Regeneration, Ministry of Education and Tianjin Municipal Government, Tianjin 300052, China.; Chinese Glioma Genome Atlas Network (CGGA).
Zhang S; Laboratory of Neuro-Oncology, Tianjin Neurological Institute, Department of Neurosurgery, Tianjin Medical University General Hospital and Key Laboratory of Neurotrauma, Variation, and Regeneration, Ministry of Education and Tianjin Municipal Government, Tianjin 300052, China.
Zhang KN; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100160, China.; Chinese Glioma Genome Atlas Network (CGGA).
Liu YQ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100160, China.; Chinese Glioma Genome Atlas Network (CGGA).
Zhao Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100160, China.; Chinese Glioma Genome Atlas Network (CGGA).
Jiang T; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100160, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100160, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA).
Wang YZ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing 100160, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100160, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA).
Kang CS; Laboratory of Neuro-Oncology, Tianjin Neurological Institute, Department of Neurosurgery, Tianjin Medical University General Hospital and Key Laboratory of Neurotrauma, Variation, and Regeneration, Ministry of Education and Tianjin Municipal Government, Tianjin 300052, China.; Chinese Glioma Genome Atlas Network (CGGA).; Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, China.
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Źródło :
Aging [Aging (Albany NY)] 2019 Feb 27; Vol. 11 (4), pp. 1204-1225.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor*
Gene Expression Regulation, Neoplastic*
Sequence Analysis, RNA*
Brain Neoplasms/*metabolism
Glioma/*metabolism
Computational Biology ; Disease Progression ; Humans ; Methylation ; Prognosis ; Transcriptome
Czasopismo naukowe
Tytuł :
Acidosis enhances the self-renewal and mitochondrial respiration of stem cell-like glioma cells through CYP24A1-mediated reduction of vitamin D.
Autorzy :
Hu P; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Li S; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Tian N; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Hu Y; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Li D; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Qi Y; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Wei Z; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Wei Q; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Li Y; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Yin B; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Jiang T; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yuan J; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Qiang B; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China.
Han W; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China. .
Peng X; State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, 100005, Beijing, China. .; Institute of Medical Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Kunming, China. .
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Źródło :
Cell death & disease [Cell Death Dis] 2019 Jan 10; Vol. 10 (1), pp. 25. Date of Electronic Publication: 2019 Jan 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acidosis/*metabolism
Brain Neoplasms/*metabolism
Calcitriol/*metabolism
Glioma/*metabolism
Mitochondria/*metabolism
Neoplastic Stem Cells/*metabolism
Vitamin D3 24-Hydroxylase/*metabolism
Acidosis/chemically induced ; Acidosis/genetics ; Animals ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Cell Self Renewal/drug effects ; Culture Media, Serum-Free/chemistry ; Glioma/pathology ; Heterografts ; Humans ; Hydrochloric Acid/pharmacology ; Hydrogen-Ion Concentration/drug effects ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Mitochondria/genetics ; Phenotype ; Sodium Hydroxide/pharmacology ; Transcriptome ; Tumor Microenvironment/drug effects ; Vitamin D3 24-Hydroxylase/genetics
Czasopismo naukowe
Tytuł :
Amino acid metabolism-related gene expression-based risk signature can better predict overall survival for glioma.
Autorzy :
Liu YQ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Chai RC; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Wang YZ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wang Z; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Liu X; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.
Jiang T; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing, China.; Chinese Glioma Genome Atlas Network (CGGA), Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
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Źródło :
Cancer science [Cancer Sci] 2019 Jan; Vol. 110 (1), pp. 321-333. Date of Electronic Publication: 2018 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Gene Expression Regulation, Neoplastic*
Amino Acids/*metabolism
Brain Neoplasms/*genetics
Glioma/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Brain Neoplasms/metabolism ; Child ; Cluster Analysis ; Female ; Glioma/metabolism ; Humans ; Male ; Middle Aged ; Prognosis ; Risk Factors ; Survival Analysis ; Young Adult
Czasopismo naukowe
Tytuł :
A novel analytical model of MGMT methylation pyrosequencing offers improved predictive performance in patients with gliomas.
Autorzy :
Chai RC; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Liu YQ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhang KN; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhao Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wang KY; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Jiang T; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Genome Atlas, Beijing, China.
Wang YZ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China. .; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. .; Chinese Glioma Genome Atlas, Beijing, China. .
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Źródło :
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2019 Jan; Vol. 32 (1), pp. 4-15. Date of Electronic Publication: 2018 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Methylation*
Brain Neoplasms/*genetics
DNA Modification Methylases/*genetics
DNA Repair Enzymes/*genetics
Glioma/*genetics
High-Throughput Nucleotide Sequencing/*methods
Tumor Suppressor Proteins/*genetics
Adult ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Identification of an energy metabolism-related signature associated with clinical prognosis in diffuse glioma.
Autorzy :
Zhou Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Department of Cerebral Surgery, The People's Hospital of Gongan County. Hu Bei, Gongan, 434300, China.
Huang R; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, 100050, China.
Chai R; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, 100050, China.
Zhou X; Department of Cerebral Surgery, The People's Hospital of Gongan County. Hu Bei, Gongan, 434300, China.
Hu Z; Department of Cerebral Surgery, The People's Hospital of Gongan County. Hu Bei, Gongan, 434300, China.
Wang W; Department of Cerebral Surgery, The People's Hospital of Gongan County. Hu Bei, Gongan, 434300, China.
Chen B; Department of Cerebral Surgery, The People's Hospital of Gongan County. Hu Bei, Gongan, 434300, China.
Deng L; Department of Cerebral Surgery, The People's Hospital of Gongan County. Hu Bei, Gongan, 434300, China.
Liu Y; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, 100050, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, 100050, China.
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Źródło :
Aging [Aging (Albany NY)] 2018 Nov 08; Vol. 10 (11), pp. 3185-3209.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*metabolism
Energy Metabolism/*physiology
Glioma/*metabolism
Glioma/*pathology
Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Prognosis ; Proportional Hazards Models
Czasopismo naukowe
Tytuł :
Long noncoding RNA LINC00152 is a potential prognostic biomarker in patients with high-grade glioma.
Autorzy :
Wang W; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Wu F; Chinese Glioma Cooperative Group (CGCG), Beijing, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Zhao Z; Chinese Glioma Cooperative Group (CGCG), Beijing, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Wang KY; Chinese Glioma Cooperative Group (CGCG), Beijing, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Huang RY; Chinese Glioma Cooperative Group (CGCG), Beijing, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Wang HY; Chinese Glioma Cooperative Group (CGCG), Beijing, China.; Department of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Lan Q; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Wang JF; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Zhao JZ; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
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Źródło :
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2018 Oct; Vol. 24 (10), pp. 957-966. Date of Electronic Publication: 2018 Mar 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Neoplasms/*metabolism
Gene Expression Regulation, Neoplastic/*physiology
Glioma/*metabolism
RNA, Long Noncoding/*metabolism
Animals ; Brain Neoplasms/diagnosis ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Female ; Glioma/diagnosis ; Humans ; Kaplan-Meier Estimate ; Male ; Mice, Nude ; Microarray Analysis ; Neoplasm Invasiveness/genetics ; Prognosis ; Proportional Hazards Models ; RNA, Long Noncoding/genetics ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Transduction, Genetic ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
An immune-related lncRNA signature for patients with anaplastic gliomas.
Autorzy :
Wang W; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantan Xili, Dongcheng District, Beijing, 100050, China.; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215123, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
Zhao Z; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Yang F; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantan Xili, Dongcheng District, Beijing, 100050, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Wang H; Department of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Wu F; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Liang T; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantan Xili, Dongcheng District, Beijing, 100050, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Yan X; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Li J; Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.
Lan Q; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215123, China.
Wang J; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantan Xili, Dongcheng District, Beijing, 100050, China. .; Chinese Glioma Cooperative Group (CGCG), Beijing, China. .; China National Clinical Research Center for Neurological Diseases, Beijing, China. .
Zhao J; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantan Xili, Dongcheng District, Beijing, 100050, China. .; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215123, China. .; China National Clinical Research Center for Neurological Diseases, Beijing, China. .
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Źródło :
Journal of neuro-oncology [J Neurooncol] 2018 Jan; Vol. 136 (2), pp. 263-271. Date of Electronic Publication: 2017 Nov 23.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Brain Neoplasms/*genetics
Brain Neoplasms/*immunology
Glioma/*genetics
Glioma/*immunology
RNA, Long Noncoding/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/immunology ; Female ; Genetic Predisposition to Disease ; Humans ; Kaplan-Meier Estimate ; Male ; Microarray Analysis ; Middle Aged
Czasopismo naukowe
Tytuł :
Prognostic value of ion channel genes in Chinese patients with gliomas based on mRNA expression profiling.
Autorzy :
Lu FF; Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, 253# Gongye Road, Guangzhou, China.; The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Wang HY; Department of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Meishan Road 81, Hefei, 230032, Anhui, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
He XZ; Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, 253# Gongye Road, Guangzhou, China.; The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Liang TY; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Wang W; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantan Xili, Dongcheng District, Beijing, 100050, China.
Hu HM; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Wu F; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Liu YW; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China. .; Department of Radiation Therapy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. .; Chinese Glioma Cooperative Group (CGCG), Beijing, China. .; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantan Xili, Dongcheng District, Beijing, 100050, China. .
Zhang SZ; Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, 253# Gongye Road, Guangzhou, China. .; The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China. .
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Źródło :
Journal of neuro-oncology [J Neurooncol] 2017 Sep; Vol. 134 (2), pp. 397-405. Date of Electronic Publication: 2017 Jul 27.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*genetics
Glioma/*genetics
Ion Channels/*genetics
Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Brain Neoplasms/surgery ; Follow-Up Studies ; Gene Expression Profiling ; Genetic Association Studies ; Genetic Testing ; Glioma/metabolism ; Glioma/pathology ; Glioma/surgery ; Humans ; Ion Channels/metabolism ; Isocitrate Dehydrogenase/genetics ; Microarray Analysis ; Mutation ; Neoplasm Grading ; Prognosis ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
LncRNA profile study reveals four-lncRNA signature associated with the prognosis of patients with anaplastic gliomas.
Autorzy :
Wang W; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Yang F; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Zhang L; Department of Ophthalmology, School of Medicine, Shandong University, Jinan, China.
Chen J; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Zhao Z; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Wang H; Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Wu F; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Liang T; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Yan X; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Li J; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Lan Q; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Wang J; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Chinese Glioma Cooperative Group (CGCG), Beijing, China.
Zhao J; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.
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Źródło :
Oncotarget [Oncotarget] 2016 Nov 22; Vol. 7 (47), pp. 77225-77236.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*pathology
Gene Expression Profiling/*methods
Glioma/*pathology
RNA, Long Noncoding/*genetics
Brain Neoplasms/genetics ; Cell Line, Tumor ; Databases, Genetic ; Female ; Gene Expression Regulation, Neoplastic ; Glioma/genetics ; Humans ; Male ; Neoplasm Grading ; Prognosis ; Survival Analysis
Czasopismo naukowe

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