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Tytuł :
LncRNA WT1-AS downregulates lncRNA UCA1 to suppress non-small cell lung cancer and predicts poor survival.
Autorzy :
Wan Y; Department of Thoracic Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, No.3002, Sungang west road, Futian district, Shenzhen City, 518000, People's Republic of China.
Yao D; Department of Thoracic Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, No.3002, Sungang west road, Futian district, Shenzhen City, 518000, People's Republic of China.
Fang F; Department of Thoracic Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, No.3002, Sungang west road, Futian district, Shenzhen City, 518000, People's Republic of China.
Wang Y; Department of Thoracic Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, No.3002, Sungang west road, Futian district, Shenzhen City, 518000, People's Republic of China.
Wu G; Department of Thoracic Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, No.3002, Sungang west road, Futian district, Shenzhen City, 518000, People's Republic of China.
Qian Y; Department of Thoracic Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, No.3002, Sungang west road, Futian district, Shenzhen City, 518000, People's Republic of China. .
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Źródło :
BMC cancer [BMC Cancer] 2021 Jan 29; Vol. 21 (1), pp. 104. Date of Electronic Publication: 2021 Jan 29.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*genetics
Carcinoma, Non-Small-Cell Lung/*mortality
Lung Neoplasms/*mortality
RNA, Long Noncoding/*genetics
Adult ; Aged ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Movement ; Cell Proliferation ; Female ; Follow-Up Studies ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Prognosis ; Signal Transduction ; Survival Rate ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
IQGAP3 interacts with Rad17 to recruit the Mre11-Rad50-Nbs1 complex and contributes to radioresistance in lung cancer.
Autorzy :
Zeng Y; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Jie X; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Wu B; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Wu G; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Liu L; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
Xu S; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2020 Nov 28; Vol. 493, pp. 254-265. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Radiation Tolerance*
Up-Regulation*
Cell Cycle Proteins/*metabolism
GTPase-Activating Proteins/*metabolism
Lung Neoplasms/*pathology
A549 Cells ; Acid Anhydride Hydrolases/metabolism ; Animals ; Cell Line, Tumor ; DNA-Binding Proteins/metabolism ; Epithelial-Mesenchymal Transition ; Female ; GTPase-Activating Proteins/genetics ; Gene Deletion ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/therapy ; MRE11 Homologue Protein/metabolism ; Mice ; Neoplasm Transplantation ; Nuclear Proteins/metabolism ; Prognosis ; Signal Transduction
Czasopismo naukowe
Tytuł :
Diagnosis of Invasive Lung Adenocarcinoma Based on Chest CT Radiomic Features of Part-Solid Pulmonary Nodules: A Multicenter Study.
Autorzy :
Wu G; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Woodruff HC; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Shen J; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Refaee T; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Sanduleanu S; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Ibrahim A; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Leijenaar RTH; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Wang R; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Xiong J; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Bian J; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Wu J; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
Lambin P; From the Departments of Precision Medicine (G.W., H.C.W., T.R., S.S., I.A., R.T.H.L., P.L.) and Radiology and Nuclear Medicine (H.C.W., I.A., P.L.), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, the Netherlands; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian 116001, People's Republic of China (G.W., J.S., J.W.); Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China (R.W.); and Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China (J.X., J.B.).
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Źródło :
Radiology [Radiology] 2020 Nov; Vol. 297 (2), pp. 451-458. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Tomography, X-Ray Computed*
Adenocarcinoma of Lung/*diagnostic imaging
Lung Neoplasms/*diagnostic imaging
Neoplasm Invasiveness/*diagnostic imaging
Solitary Pulmonary Nodule/*diagnostic imaging
Adenocarcinoma of Lung/pathology ; Aged ; Female ; Humans ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Invasiveness/pathology ; Retrospective Studies ; Solitary Pulmonary Nodule/pathology
Czasopismo naukowe
Tytuł :
CDK5 Activates Hippo Signaling to Confer Resistance to Radiation Therapy Via Upregulating TAZ in Lung Cancer.
Autorzy :
Zeng Y; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu Q; Department of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang Y; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Tian C; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang Q; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhao Y; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu L; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
Wu G; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
Xu S; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
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Źródło :
International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2020 Nov 01; Vol. 108 (3), pp. 758-769. Date of Electronic Publication: 2020 May 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cyclin-Dependent Kinase 5/*metabolism
Lung Neoplasms/*radiotherapy
Protein-Serine-Threonine Kinases/*metabolism
Radiation Tolerance/*physiology
Transcription Factors/*metabolism
A549 Cells ; Animals ; Cell Line, Tumor ; Comet Assay ; Cyclin-Dependent Kinase 5/deficiency ; Cyclin-Dependent Kinase 5/genetics ; DNA Damage ; DNA Repair ; Disease Progression ; Down-Regulation ; Fluorescent Antibody Technique ; Gene Knockdown Techniques ; Gene Silencing ; Heterografts ; Histones/analysis ; Humans ; Lung Neoplasms/chemistry ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Mice ; Neoplasm Proteins/deficiency ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; RNA, Small Interfering ; Rad51 Recombinase/analysis ; Up-Regulation
Czasopismo naukowe
Tytuł :
Mutations in the exons of epidermal growth factor receptor gene are associated with clinicopathological features of lung cancer.
Autorzy :
Wan Y; Thoracic Surgery, The First Affiliated Hospital of Shenzhen University/ Thoracic Surgery, Shenzhen Second People's Hospital, Shenzhen, China.
Wang Y; Thoracic Surgery, The First Affiliated Hospital of Shenzhen University/ Thoracic Surgery, Shenzhen Second People's Hospital, Shenzhen, China.
Fang F; Thoracic Surgery, The First Affiliated Hospital of Shenzhen University/ Thoracic Surgery, Shenzhen Second People's Hospital, Shenzhen, China.
Wu G; Thoracic Surgery, The First Affiliated Hospital of Shenzhen University/ Thoracic Surgery, Shenzhen Second People's Hospital, Shenzhen, China.
Zhang M; Internal Medicine, Shenzhen Prevention and Treatment Center for Occupational Diseases, Shenzhen, China. Electronic address: .
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Źródło :
Asian journal of surgery [Asian J Surg] 2020 Oct; Vol. 43 (10), pp. 1037-1038. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Letter
MeSH Terms :
Genetic Association Studies*
Mutation*
Carcinoma, Non-Small-Cell Lung/*genetics
Carcinoma, Non-Small-Cell Lung/*pathology
Exons/*genetics
Genes, erbB-1/*genetics
Lung Neoplasms/*genetics
Lung Neoplasms/*pathology
Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/mortality ; Cell Proliferation/genetics ; Cell Transformation, Neoplastic/genetics ; Female ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/mortality ; Male ; Middle Aged ; Neovascularization, Pathologic/genetics ; Retrospective Studies ; Survival Rate ; Treatment Outcome
Opinia redakcyjna
Tytuł :
Combination of Bronchial Arterial Infusion Chemotherapy plus Drug-Eluting Embolic Transarterial Chemoembolization for Treatment of Advanced Lung Cancer-A Retrospective Analysis of 23 Patients.
Autorzy :
Zeng Y; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China.
Yin M; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China.
Zhao Y; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China.
Liu Y; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China.
Li X; Department of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China.
Qi Y; Department of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China.
Ma Y; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China.
Li Z; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China.
Li C; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China.
Wu G; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Rd., Zhengzhou 450052, China. Electronic address: .
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Źródło :
Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2020 Oct; Vol. 31 (10), pp. 1645-1653. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article
MeSH Terms :
Bronchial Arteries*
Chemoembolization, Therapeutic*/adverse effects
Chemoembolization, Therapeutic*/mortality
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Doxorubicin/*analogs & derivatives
Irinotecan/*administration & dosage
Lung Neoplasms/*therapy
Topoisomerase I Inhibitors/*administration & dosage
Topoisomerase II Inhibitors/*administration & dosage
Aged ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Disease Progression ; Doxorubicin/administration & dosage ; Doxorubicin/adverse effects ; Female ; Humans ; Infusions, Intra-Arterial ; Irinotecan/adverse effects ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Staging ; Retrospective Studies ; Risk Factors ; Time Factors ; Topoisomerase I Inhibitors/adverse effects ; Topoisomerase II Inhibitors/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
BMP2 signalling activation enhances bone metastases of non-small cell lung cancer.
Autorzy :
Huang F; Central Laboratory, First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Fujian Platform for Medical Research at First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou, China.; Key Laboratory of Radiation Biology of Fujian Province Universities, Fuzhou, China.
Cao Y; CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Wu G; Department of Orthopedics, First Affiliated hospital, Fujian Medical University, Fuzhou, China.
Chen J; Central Laboratory, First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Fujian Platform for Medical Research at First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou, China.; Key Laboratory of Radiation Biology of Fujian Province Universities, Fuzhou, China.
CaihongWang; Key Laboratory of Radiation Biology of Fujian Province Universities, Fuzhou, China.; Department of Radiation Oncology, First Affiliated hospital, Fujian Medical University, Fuzhou, China.
Lin W; Department of Chemotherapy, First Affiliated hospital, Fujian Medical University, Fuzhou, China.
Lan R; Central Laboratory, First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Fujian Platform for Medical Research at First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou, China.; Key Laboratory of Radiation Biology of Fujian Province Universities, Fuzhou, China.
Wu B; Central Laboratory, First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Fujian Platform for Medical Research at First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou, China.; Key Laboratory of Radiation Biology of Fujian Province Universities, Fuzhou, China.
Xie X; Department of Chemotherapy, First Affiliated hospital, Fujian Medical University, Fuzhou, China.
Hong J; Key Laboratory of Radiation Biology of Fujian Province Universities, Fuzhou, China.; Department of Radiation Oncology, First Affiliated hospital, Fujian Medical University, Fuzhou, China.
Fu L; Central Laboratory, First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Fujian Platform for Medical Research at First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Fujian Key Laboratory of Individualized Active Immunotherapy, Fuzhou, China.; Key Laboratory of Radiation Biology of Fujian Province Universities, Fuzhou, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Sep; Vol. 24 (18), pp. 10768-10784. Date of Electronic Publication: 2020 Aug 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Morphogenetic Protein 2/*physiology
Bone Neoplasms/*secondary
Carcinoma, Lewis Lung/*secondary
Carcinoma, Non-Small-Cell Lung/*secondary
Lung Neoplasms/*physiopathology
Neoplasm Proteins/*physiology
A549 Cells ; Animals ; Bone Neoplasms/complications ; Bone Neoplasms/physiopathology ; Carcinoma, Lewis Lung/physiopathology ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/physiopathology ; Cell Movement ; Female ; Fibroblasts/metabolism ; Humans ; Kaplan-Meier Estimate ; Lung Neoplasms/mortality ; Mice ; Mice, Inbred C57BL ; Neoplasm Invasiveness/physiopathology ; Osteoblasts/pathology ; Osteolysis/etiology ; Osteolysis/physiopathology ; RAW 264.7 Cells ; Signal Transduction ; Specific Pathogen-Free Organisms ; Stromal Cells/metabolism
Czasopismo naukowe
Tytuł :
CDK7 inhibitor THZ1 enhances antiPD-1 therapy efficacy via the p38α/MYC/PD-L1 signaling in non-small cell lung cancer.
Autorzy :
Wang J; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zhang R; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Lin Z; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zhang S; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Chen Y; Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Tang J; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Hong J; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zhou X; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zong Y; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Xu Y; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Meng R; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Xu S; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Liu L; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zhang T; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Yang K; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Dong X; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
Wu G; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
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Źródło :
Journal of hematology & oncology [J Hematol Oncol] 2020 Jul 20; Vol. 13 (1), pp. 99. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Targeted Therapy*
Carcinoma, Non-Small-Cell Lung/*drug therapy
Cyclin-Dependent Kinases/*antagonists & inhibitors
Imidazoles/*pharmacology
Lung Neoplasms/*drug therapy
Neoplasm Proteins/*antagonists & inhibitors
Phenylenediamines/*therapeutic use
Programmed Cell Death 1 Receptor/*antagonists & inhibitors
Pyridines/*pharmacology
Pyrimidines/*therapeutic use
Signal Transduction/*drug effects
Animals ; B7-H1 Antigen/biosynthesis ; B7-H1 Antigen/genetics ; B7-H1 Antigen/physiology ; CD8-Positive T-Lymphocytes/immunology ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/immunology ; Cyclin-Dependent Kinases/biosynthesis ; Cyclin-Dependent Kinases/genetics ; Drug Resistance, Neoplasm ; Drug Synergism ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/immunology ; Lymphocytes, Tumor-Infiltrating/immunology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Nude ; Mitogen-Activated Protein Kinase 14/antagonists & inhibitors ; Mitogen-Activated Protein Kinase 14/physiology ; Neoplasm Proteins/biosynthesis ; Neoplasm Proteins/genetics ; Phenylenediamines/administration & dosage ; Phenylenediamines/pharmacology ; Prognosis ; Proto-Oncogene Proteins c-myc/antagonists & inhibitors ; Proto-Oncogene Proteins c-myc/physiology ; Pyrimidines/administration & dosage ; Pyrimidines/pharmacology ; RNA Interference ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; RNA, Neoplasm/biosynthesis ; RNA, Neoplasm/genetics ; Tissue Array Analysis ; Transcriptome ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
[Preoperative Pulmonary Nodule Localization Methods:A Comparison of Microcoil and Sclerosing Agent].
Autorzy :
Wu G; Department of Thoracic Surgery, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001, China.
Wu X; Department of Thoracic Surgery, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001, China.
Xu M; Department of Thoracic Surgery, the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital), Hefei 230001, China.
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Źródło :
Zhongguo fei ai za zhi = Chinese journal of lung cancer [Zhongguo Fei Ai Za Zhi] 2020 Jun 20; Vol. 23 (6), pp. 429-435.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Preoperative Period*
Lung Neoplasms/*diagnostic imaging
Lung Neoplasms/*surgery
Surgery, Computer-Assisted/*instrumentation
Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Surgery, Computer-Assisted/adverse effects ; Tomography, X-Ray Computed ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Preoperative CT-based radiomics combined with intraoperative frozen section is predictive of invasive adenocarcinoma in pulmonary nodules: a multicenter study.
Autorzy :
Wu G; The D-Lab: Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands. g.wu@maastrichtuniversity.nl.; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian, 116001, People's Republic of China. g.wu@maastrichtuniversity.nl.
Woodruff HC; The D-Lab: Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Sanduleanu S; The D-Lab: Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Refaee T; The D-Lab: Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Jochems A; The D-Lab: Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Leijenaar R; The D-Lab: Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Gietema H; Department of Radiology, Maastricht University Medical Center+, Maastricht, The Netherlands.
Shen J; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian, 116001, People's Republic of China.
Wang R; Department of Radiology, The Fifth Hospital of Dalian, Dalian, People's Republic of China.
Xiong J; Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China.
Bian J; Department of Radiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China.
Wu J; Department of Radiology, Affiliated Zhongshan Hospital of Dalian University, 6 Jiefang Street, Dalian, 116001, People's Republic of China. .
Lambin P; The D-Lab: Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
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Źródło :
European radiology [Eur Radiol] 2020 May; Vol. 30 (5), pp. 2680-2691. Date of Electronic Publication: 2020 Jan 31.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Adenocarcinoma in Situ/*diagnostic imaging
Adenocarcinoma of Lung/*diagnostic imaging
Lung Neoplasms/*diagnostic imaging
Multiple Pulmonary Nodules/*diagnostic imaging
Solitary Pulmonary Nodule/*diagnostic imaging
Adenocarcinoma in Situ/pathology ; Adenocarcinoma in Situ/surgery ; Adenocarcinoma of Lung/pathology ; Adenocarcinoma of Lung/surgery ; Area Under Curve ; Female ; Frozen Sections ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Male ; Middle Aged ; Multiple Pulmonary Nodules/pathology ; Multiple Pulmonary Nodules/surgery ; Preoperative Care ; ROC Curve ; Retrospective Studies ; Solitary Pulmonary Nodule/pathology ; Tomography, X-Ray Computed/methods
Czasopismo naukowe
Tytuł :
Monitoring of lung malignant epithelial cells by gene methylation analysis in the conditionally reprogrammed cell cultures.
Autorzy :
Wu GD; Department of Thoracic Surgery, 2nd People's Hospital of Shenzhen, Shenzhen, China.
Xiao YG; USK Bioscience, Shenzhen, China.
Fang FY; Department of Thoracic Surgery, 2nd People's Hospital of Shenzhen, Shenzhen, China.
Yao D; Department of Thoracic Surgery, 2nd People's Hospital of Shenzhen, Shenzhen, China.
Liu J; USK Bioscience, Shenzhen, China.
Cao YH; USK Bioscience, Shenzhen, China.
Mao Y; USK Bioscience, Shenzhen, China.
Yu B; Feinberg School of Medicine, Northwestern University, Chicago, United States.
Yao TR; USK Bioscience, Shenzhen, China.
Wu YM; Department of Histopathology, Xiaolan People's Hospital, Zhongshan, China.
Qian YH; Department of Thoracic Surgery, 2nd People's Hospital of Shenzhen, Shenzhen, China.
Yu DH; USK Bioscience, Shenzhen, China.
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Źródło :
Neoplasma [Neoplasma] 2020 May; Vol. 67 (3), pp. 692-699. Date of Electronic Publication: 2020 Mar 24.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Biomarkers, Tumor/*genetics
Epithelial Cells/*pathology
Lung Neoplasms/*diagnosis
Homeodomain Proteins/genetics ; Humans ; Lung Neoplasms/genetics ; Receptors, Prostaglandin E, EP4 Subtype/genetics
Czasopismo naukowe
Tytuł :
Safety and Feasibility of Low-Dose Apatinib Combined with S-1 as the Second-Line Therapy or Beyond in Chinese Patients with Pulmonary and Hepatic Metastasis of Nasopharyngeal Carcinoma.
Autorzy :
Zhou L; Department of Radiation Oncology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province 570311, People's Republic of China.
Lin J; Department of Radiation Oncology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province 570311, People's Republic of China.
Wu G; Department of Radiation Oncology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province 570311, People's Republic of China.
Chen J; Department of Radiation Oncology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province 570311, People's Republic of China.
Huang X; Department of Radiation Oncology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province 570311, People's Republic of China.
Zhang S; Department of Radiation Oncology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province 570311, People's Republic of China.
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Źródło :
Drug design, development and therapy [Drug Des Devel Ther] 2020 Mar 30; Vol. 14, pp. 1257-1262. Date of Electronic Publication: 2020 Mar 30 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Carcinoma, Non-Small-Cell Lung/*drug therapy
Liver Neoplasms/*drug therapy
Lung Neoplasms/*drug therapy
Nasopharyngeal Carcinoma/*drug therapy
Nasopharyngeal Neoplasms/*drug therapy
Administration, Oral ; Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Asian Continental Ancestry Group ; Carcinoma, Non-Small-Cell Lung/secondary ; Combined Modality Therapy ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Drug Combinations ; Feasibility Studies ; Female ; Humans ; Liver Neoplasms/secondary ; Lung Neoplasms/secondary ; Male ; Middle Aged ; Oxonic Acid/administration & dosage ; Oxonic Acid/adverse effects ; Oxonic Acid/therapeutic use ; Pyridines/administration & dosage ; Pyridines/adverse effects ; Pyridines/therapeutic use ; Survival Rate ; Tegafur/administration & dosage ; Tegafur/adverse effects ; Tegafur/therapeutic use ; Young Adult
Czasopismo naukowe
Tytuł :
Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.
Autorzy :
Wong JYY; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA. Electronic address: .
Zhang H; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Hsiung CA; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Shiraishi K; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.
Yu K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Matsuo K; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan; Department of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Wong MP; Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong.
Hong YC; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Wang J; Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Seow WJ; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Wang Z; Cancer Genomics Research Laboratory, Leidos Biomedical Research Inc, Gaithersburg, MD, USA; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Song M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Department of Statistics, Sookmyung Women's University, Seoul, Republic of Korea.
Kim HN; Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Chang IS; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.
Chatterjee N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Hu W; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Wu C; Department of Etiology & Carcinogenesis and State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Mitsudomi T; Division of Thoracic Surgery, Kinki University School of Medicine, Sayama, Japan.
Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Kim JH; Department of Integrative Bioscience & Biotechnology, Sejong University, Seoul, Republic of Korea.
Seow A; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Caporaso NE; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Shin MH; Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Chung LP; Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong.
An SJ; Guangdong Lung Cancer Institute, Medical Research Center and Cancer Center of Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Wang P; Department of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
Yang Y; Shanghai Pulmonary Hospital, Shanghai, China.
Zheng H; Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Yatabe Y; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Central Hospital, Nagoya, Japan.
Zhang XC; Guangdong Lung Cancer Institute, Medical Research Center and Cancer Center of Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Kim YT; Department of Thoracic and Cardiovascular Surgery, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Yin Z; Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China.
Kim YC; Lung and Esophageal Cancer Clinic, Chonnam National University Hwasun Hospital, Hwasun-eup, Republic of Korea; Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Bassig BA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Chang J; Department of Etiology & Carcinogenesis and State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ho JCM; Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong.
Ji BT; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Daigo Y; Department of Medical Oncology and Cancer Center, Shiga University of Medical Science, Otsu, Japan; Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Ito H; Division of Cancer Information and Control, Aichi Cancer Center Research Institute, Nagoya, Japan; Department of Descriptive Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Momozawa Y; Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan.
Ashikawa K; Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan.
Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Honda T; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.
Hosgood HD; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Sakamoto H; Division of Genetics, National Cancer Center Research Institute, Tokyo, Japan.
Kunitoh H; Department of Medical Oncology, Japanese Red Cross Medical Center, Tokyo, Japan.
Tsuta K; Department of Pathology and Laboratory Medicine, Kansai Medical University, Osaka, Japan.
Watanabe SI; Division of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan.
Kubo M; Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan.
Miyagi Y; Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Kanagawa, Japan.
Nakayama H; Department of Thoracic Surgery, Kanagawa Cancer Center, Kanagawa, Japan.
Matsumoto S; Division of Translational Research, Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, Chiba, Japan.
Tsuboi M; Department of Thoracic Surgery, National Cancer Center Hospital East, Chiba, Japan.
Goto K; Department of Thoracic Oncology, National Cancer Center Hospital East, Japan.
Shi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Song L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Hua X; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Takahashi A; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan; Department of Genomic Medicine, Research Institute, National Cerebral and Cardiovascular Center, Osaka, Japan.
Goto A; Department of Cellular and Organ Pathology, Graduate School of Medicine, Akita University, Akita City, Japan.
Minamiya Y; Department of Thoracic Surgery, Graduate School of Medicine, Akita University, Akita City, Japan.
Shimizu K; Department of Integrative Center of General Surgery, Gunma University Hospital, Gunma, Japan.
Tanaka K; Department of Integrative Center of General Surgery, Gunma University Hospital, Gunma, Japan.
Wei F; China National Environmental Monitoring Center, Beijing, China.
Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Su J; Guangdong Lung Cancer Institute, Medical Research Center and Cancer Center of Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Kim YH; Department of Internal Medicine, Division of Oncology/Hematology, College of Medicine, Korea University Anam Hospital, Seoul, Republic of Korea.
Oh IJ; Lung and Esophageal Cancer Clinic, Chonnam National University Hwasun Hospital, Hwasun-eup, Republic of Korea; Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Song F; Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Su WC; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen YM; Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Chang GC; School of Medicine, Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Chen KY; Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Huang MS; Department of Internal Medicine, E-Da Cancer Hospital, School of Medicine, I-Shou University, Kaohsiung, Taiwan.
Chien LH; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.
Xiang YB; State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Park JY; Lung Cancer Center, Kyungpook National University Medical Center, Daegu, Republic of Korea.
Kweon SS; Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea; Jeonnam Regional Cancer Center, Chonnam National University Hwasun Hospital, Hwasun-eup, Republic of Korea.
Chen CJ; Genomic Research Center, Academia Sinica, Taipei, Taiwan.
Lee KM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Department of Environmental Health, Korea National Open University, Seoul, Republic of Korea.
Blechter B; Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Li H; Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Gao YT; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Qian B; Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Lu D; Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Liu J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore; Department of Human Genetics, Genome Institute of Singapore, Singapore; School of Life Sciences, Anhui Medical University, Hefei, China.
Jeon HS; Cancer Research Center, Kyungpook National University Medical Center, Daegu, Republic of Korea.
Hsiao CF; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Sung JS; Department of Internal Medicine, Division of Oncology/Hematology, College of Medicine, Korea University Anam Hospital, Seoul, Republic of Korea.
Tsai YH; Division of Pulmonary and Critical Care Medicine, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.
Jung YJ; Department of Thoracic and Cardiovascular Surgery, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
Guo H; Department of Occupational and Environmental Health and Ministry of Education Key Lab for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Hu Z; Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Wang WC; The Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Chung CC; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research Inc, Gaithersburg, MD, USA.
Burdett L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research Inc, Gaithersburg, MD, USA.
Yeager M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research Inc, Gaithersburg, MD, USA.
Hutchinson A; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research Inc, Gaithersburg, MD, USA.
Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Wu W; Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China.
Pang H; School of BioMedical Sciences, The University of Hong Kong, Hong Kong.
Li Y; Cancer Prevention Institute of California, Fremont, CA, USA.
Choi JE; Cancer Research Center, Kyungpook National University Medical Center, Daegu, Republic of Korea.
Park KH; Department of Internal Medicine, Division of Oncology/Hematology, College of Medicine, Korea University Anam Hospital, Seoul, Republic of Korea.
Sung SW; Department of Thoracic and Cardiovascular Surgery, Seoul St Mary's Hospital, The Catholic University of Korea, Republic of Korea.
Liu L; Department of Oncology, Cancer Center, Union Hospital, Huazhong University of Science and Technology, Wuhan, China.
Kang CH; Department of Thoracic and Cardiovascular Surgery, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
Zhu M; Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Chen CH; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Yang TY; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Xu J; School of Public Health, Li Ka Shing (LKS) Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Guan P; Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China; Key Laboratory of Cancer Etiology and Intervention, University of Liaoning Province, Shenyang, China.
Tan W; Department of Etiology & Carcinogenesis and State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wang CL; Department of Pulmonary and Critical Care, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Hsin M; Department of Cardiothoracic Surgery, Queen Mary Hospital, The University of Hong Kong, China.
Sit KY; Department of Cardiothoracic Surgery, Queen Mary Hospital, The University of Hong Kong, China.
Ho J; Department of Medicine, The University of Hong Kong, China.
Chen Y; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Choi YY; Cancer Research Center, Kyungpook National University Medical Center, Daegu, Republic of Korea.
Hung JY; Department of Internal Medicine, E-Da Cancer Hospital, School of Medicine, I-Shou University, Kaohsiung, Taiwan.
Kim JS; Division of Medical Oncology, Department of Internal Medicine, College of Medicine, Korea University Guro Hospital, Seoul, Republic of Korea.
Yoon HI; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Lin CC; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Park IK; Department of Thoracic and Cardiovascular Surgery, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
Xu P; Department of Oncology, Wuhan Iron and Steel Corporation Staff Worker Hospital, Wuhan, China.
Wang Y; Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
He Q; Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China.
Perng RP; Chest Department, Taipei Veterans General Hospital, Taipei, Taiwan.
Chen CY; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Division of Thoracic Surgery, Department of Surgery, Chung Shan Medical University Hospital, Taichung, Taiwan.
Vermeulen R; Division of Environmental Epidemiology, Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, the Netherlands.
Wu J; Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Lim WY; Agency for Integrated Care, Singapore.
Chen KC; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Li YJ; Genomic Research Center, Academia Sinica, Taipei, Taiwan.
Li J; Qujing Center for Diseases Control and Prevention, Sanjiangdadao, Qujing, China.
Chen H; Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Yu CJ; Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
Jin L; Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Chen TY; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Jiang SS; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.
Liu J; Department of Oncology, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, China.
Yamaji T; Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Hicks B; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research Inc, Gaithersburg, MD, USA.
Wyatt K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research Inc, Gaithersburg, MD, USA.
Li SA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research Inc, Gaithersburg, MD, USA.
Dai J; Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Ma H; Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Jin G; Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Song B; Department of Oncology, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, China.
Wang Z; Department of Oncology, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, China.
Cheng S; Department of Oncology, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, China.
Li X; Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China; Key Laboratory of Cancer Etiology and Intervention, University of Liaoning Province, Shenyang, China.
Ren Y; Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China; Key Laboratory of Cancer Etiology and Intervention, University of Liaoning Province, Shenyang, China.
Cui P; Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Iwasaki M; Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Shimazu T; Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Tsugane S; Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Zhu J; Shanghai Pulmonary Hospital, Shanghai, China.
Chen Y; Department of Thoracic Surgery, the Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Yunnan Cancer Center, Kunming, China.
Yang K; Department of Thoracic Surgery, the Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Yunnan Cancer Center, Kunming, China.
Jiang G; Shanghai Pulmonary Hospital, Shanghai, China.
Fei K; Shanghai Pulmonary Hospital, Shanghai, China.
Wu G; China National Environmental Monitoring Center, Beijing, China.
Lin HC; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Chen HL; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Fang YH; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Tsai FY; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.
Hsieh WS; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Yu J; Department of Oncology, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, China.
Stevens VL; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA.
Laird-Offringa IA; Department of Surgery, Department of Biochemistry and Molecular Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Marconett CN; Department of Surgery, Department of Biochemistry and Molecular Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Rieswijk L; Environmental Health Sciences Division, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Chao A; Center for Global Health, National Cancer Institute, Bethesda, MD, USA.
Yang PC; Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Wu T; Department of Occupational and Environmental Health and Ministry of Education Key Lab for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Wu YL; Guangdong Lung Cancer Institute, Medical Research Center and Cancer Center of Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Lin D; Department of Etiology & Carcinogenesis and State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chen K; Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Zhou B; Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China.
Huang YC; Department of Thoracic Surgery, the Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Yunnan Cancer Center, Kunming, China.
Kohno T; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.
Shen H; Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.
Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Rothman N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Lan Q; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
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Źródło :
Genomics [Genomics] 2020 Mar; Vol. 112 (2), pp. 1223-1232. Date of Electronic Publication: 2019 Jul 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma of Lung/*genetics
Lung Neoplasms/*genetics
Tuberculosis, Pulmonary/*genetics
Adenocarcinoma of Lung/epidemiology ; Asian Continental Ancestry Group ; Female ; Genome-Wide Association Study ; Humans ; Lung Neoplasms/epidemiology ; Mendelian Randomization Analysis ; Non-Smokers/statistics & numerical data ; Tuberculosis, Pulmonary/epidemiology
Czasopismo naukowe
Tytuł :
Prognostic Value of Site-Specific Metastases and Surgery in De Novo Stage IV Triple-Negative Breast Cancer: A Population-Based Analysis.
Autorzy :
Gu Y; Department of Oncology, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, Guangdong, China (mainland).
Wu G; Department of Oncology, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, Guangdong, China (mainland).
Zou X; Department of Oncology, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, Guangdong, China (mainland).
Huang P; Department of Oncology, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, Guangdong, China (mainland).
Yi L; Department of Oncology, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou Hospital Affiliated to Sun Yat-sen University, Meizhou, Guangdong, China (mainland).
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Źródło :
Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2020 Feb 11; Vol. 26, pp. e920432. Date of Electronic Publication: 2020 Feb 11.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Neoplasms/*mortality
Brain Neoplasms/*mortality
Liver Neoplasms/*mortality
Lung Neoplasms/*mortality
Mastectomy/*statistics & numerical data
Triple Negative Breast Neoplasms/*therapy
Aged ; Bone Neoplasms/prevention & control ; Bone Neoplasms/secondary ; Brain Neoplasms/prevention & control ; Brain Neoplasms/secondary ; Breast/pathology ; Breast/surgery ; Chemotherapy, Adjuvant/statistics & numerical data ; Female ; Humans ; Kaplan-Meier Estimate ; Liver Neoplasms/prevention & control ; Liver Neoplasms/secondary ; Lung Neoplasms/prevention & control ; Lung Neoplasms/secondary ; Mastectomy/methods ; Middle Aged ; Neoplasm Staging ; Prognosis ; Retrospective Studies ; Risk Assessment ; Risk Factors ; SEER Program/statistics & numerical data ; Treatment Outcome ; Triple Negative Breast Neoplasms/diagnosis ; Triple Negative Breast Neoplasms/mortality ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Efficacy, safety, and biomarker analysis of ensartinib in crizotinib-resistant, ALK-positive non-small-cell lung cancer: a multicentre, phase 2 trial.
Autorzy :
Yang Y; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
Zhou J; Department of Respiratory Disease, Thoracic Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Zhou J; Department of Respiratory Disease, Thoracic Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Feng J; Department of Medical Oncology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Zhuang W; Department of Thoracic Oncology, Fujian Provincial Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou, China.
Chen J; Department of Medical Oncology-Chest, Hunan Cancer Hospital, Changsha, China.
Zhao J; Department of Thoracic Oncology, Beijing Cancer Hospital, Beijing, China.
Zhong W; Department of Pulmonary Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Zhao Y; Respiratory Department of Internal Medicine, Henan Provincial Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
Zhang Y; Thoracic Medical Oncology, Zhejiang Cancer Hospital, Hangzhou, China.
Song Y; Division of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Hu Y; Department of Oncology, Chinese PLA General Hospital, Beijing, China.
Yu Z; Department of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Gong Y; Department of Thoracic Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Chen Y; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ye F; Department of Medical Oncology, Cancer Hospital, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, China.
Zhang S; Department of Medical Oncology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Cao L; Respiratory Medicine, The First Affiliated Hospital of the University of Science and Technology of China, Anhui Provincial Hospital, Hefei, China.
Fan Y; Thoracic Medical Oncology, Zhejiang Cancer Hospital, Hangzhou, China.
Wu G; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Guo Y; Pulmonary & Critical Care Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhou C; Respiratory Medicine Department, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Ma K; Cancer Center, The First Hospital of Jilin University, Changchun, China.
Fang J; Department of Thoracic Oncology, Beijing Cancer Hospital, Beijing, China.
Feng W; Department of Head and Neck and Thoracic Medical Oncology, The First People's Hospital Of Foshan, Foshan, China.
Liu Y; Oncology Medicine, The First Hospital of China Medical University, Shenyang, China.
Zheng Z; Oncology Department, General Hospital of Northern Theater Command, Shenyang, China.
Li G; 2nd Department of Thoracic Surgery, Yunnan Cancer Hospital, Kunming, China.
Wu N; Department of Diagnostic Radiology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Song W; Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Liu X; Department of Pulmonary Oncology, The Fifth Medical Centre Chinese PLA General Hospital, Beijing, China.
Zhao S; Department of Diagnostic Radiology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Ding L; Betta Pharmaceuticals, Hangzhou, China.
Mao L; Betta Pharmaceuticals, Hangzhou, China.
Selvaggi G; X-covery Holdings, Palm Beach Gardens, FL, USA.
Yuan X; Betta Pharmaceuticals, Hangzhou, China.
Fu Y; Betta Pharmaceuticals, Hangzhou, China.
Wang T; Hangzhou Repugene Technology, Hangzhou, China.
Xiao S; Hangzhou Repugene Technology, Hangzhou, China.
Zhang L; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China. Electronic address: .
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Źródło :
The Lancet. Respiratory medicine [Lancet Respir Med] 2020 Jan; Vol. 8 (1), pp. 45-53. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Neoplasms/*drug therapy
Piperazines/*administration & dosage
Protein Kinase Inhibitors/*administration & dosage
Pyridazines/*administration & dosage
Anaplastic Lymphoma Kinase/drug effects ; China ; Crizotinib/therapeutic use ; Female ; Humans ; Male ; Neoplasm Metastasis/drug therapy ; Piperazines/adverse effects ; Piperazines/pharmacology ; Protein Kinase Inhibitors/adverse effects ; Protein Kinase Inhibitors/pharmacology ; Pyridazines/adverse effects ; Pyridazines/pharmacology
Czasopismo naukowe
Tytuł :
The Emerging Role of Radiomics in COPD and Lung Cancer.
Autorzy :
Refaee T; The D-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands, .; Department of Diagnostic Radiology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia, .
Wu G; The D-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Ibrahim A; The D-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.; Department of Radiology and Nuclear Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.; Division of Nuclear Medicine and Oncological Imaging, Department of Medical Physics, Centre Hospitalier Universitaire de Liège, Liège, Belgium.; Department of Nuclear Medicine and Comprehensive Diagnostic Center Aachen (CDCA), University Hospital RWTH Aachen University, Aachen, Germany.
Halilaj I; The D-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Leijenaar RTH; The D-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Rogers W; The D-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.; Department of Thoracic Oncology, IRCCS Foundation National Cancer Institute, Milan, Italy.
Gietema HA; Department of Radiology and Nuclear Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Hendriks LEL; Department of Pulmonary Diseases, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Lambin P; The D-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.; Department of Radiology and Nuclear Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Woodruff HC; The D-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.; Department of Radiology and Nuclear Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
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Źródło :
Respiration; international review of thoracic diseases [Respiration] 2020; Vol. 99 (2), pp. 99-107. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Image Processing, Computer-Assisted*
Machine Learning*
Lung Neoplasms/*diagnostic imaging
Pulmonary Disease, Chronic Obstructive/*diagnostic imaging
Artificial Intelligence ; Data Mining ; Decision Support Systems, Clinical ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Lung Neoplasms/therapy ; Neoplasm Staging ; Prognosis ; Pulmonary Disease, Chronic Obstructive/therapy ; Treatment Outcome ; Workflow
Czasopismo naukowe
Tytuł :
Real-time tumor motion monitoring and PTV margin determination in lung SBRT treatment.
Autorzy :
Liang Z; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang J; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu H; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yin Z; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang S; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Peng H; Department of Medical Physics, Wuhan University, Wuhan, China.
Wu G; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło :
Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2019 Dec; Vol. 58 (12), pp. 1786-1789. Date of Electronic Publication: 2019 Aug 09.
Typ publikacji :
Letter
MeSH Terms :
Lung Neoplasms/*diagnostic imaging
Lung Neoplasms/*radiotherapy
Radiosurgery/*methods
Radiotherapy Planning, Computer-Assisted/*methods
Algorithms ; Female ; Four-Dimensional Computed Tomography/methods ; Humans ; Lung Neoplasms/physiopathology ; Male ; Respiratory Mechanics/physiology
Opinia redakcyjna
Tytuł :
Combination of Metformin and Gefitinib as First-Line Therapy for Nondiabetic Advanced NSCLC Patients with EGFR Mutations: A Randomized, Double-Blind Phase II Trial.
Autorzy :
Li L; Department of Respiratory Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Jiang L; Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Wang Y; Department of Respiratory Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Zhao Y; Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Zhang XJ; Department of Pulmonary Medicine, People's Hospital of Henan Province, Zhengzhou, China.
Wu G; Department of Respiratory Medicine and Respiratory Intensive Care Unit, Xinqiao Hospital, Army Medical University, Chongqing, China.
Zhou X; Department of Respiratory Medicine, Southwest Hospital, Army Medical University, Chongqing, China.
Sun J; Cancer Institute, Xinqiao Hospital, Army Medical University, Chongqing, China.
Bai J; Department of Medical Oncology, People's Hospital of Shanxi Province, Xi'an, China.
Ren B; Cancer Center, Chongqing Three Gorges Central Hospital, Chongqing, China.
Tian K; Department of Respiratory Medicine, General Hospital of Chengdu Military Region of PLA, Chengdu, China.
Xu Z; Department of Respiratory Medicine and Respiratory Intensive Care Unit, Xinqiao Hospital, Army Medical University, Chongqing, China.
Xiao HL; Department of Pathology, Daping Hospital, Army Medical University, Chongqing, China.
Zhou Q; Department of Oncology, Fuling Center Hospital, Chongqing, China.
Han R; Department of Respiratory Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Chen H; Department of Respiratory Medicine, Daping Hospital, Army Medical University, Chongqing, China.
Wang H; Department of Thoracic Surgery, Southwest Hospital, Army Medical University, Chongqing, China.
Yang Z; Department of Oncology, Daping Hospital, Army Medical University, Chongqing, China.
Gao C; The Medical Department, 3D Medicines Inc., Shanghai, P.R. China.
Cai S; The Medical Department, 3D Medicines Inc., Shanghai, P.R. China.
He Y; Department of Respiratory Medicine, Daping Hospital, Army Medical University, Chongqing, China. .
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Źródło :
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2019 Dec 01; Vol. 25 (23), pp. 6967-6975. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Adenocarcinoma of Lung/*drug therapy
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Carcinoma, Non-Small-Cell Lung/*drug therapy
Carcinoma, Squamous Cell/*drug therapy
Lung Neoplasms/*drug therapy
Adenocarcinoma of Lung/genetics ; Adenocarcinoma of Lung/pathology ; Adult ; Aged ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/pathology ; ErbB Receptors/genetics ; Female ; Follow-Up Studies ; Gefitinib/administration & dosage ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Male ; Metformin/administration & dosage ; Middle Aged ; Prognosis ; Survival Rate
Czasopismo naukowe
Tytuł :
Shenqi Fuzheng Injection Ameliorates Radiation-induced Brain Injury.
Autorzy :
Chen LJ; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zhang RG; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Yu DD; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Wu G; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Dong XR; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
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Źródło :
Current medical science [Curr Med Sci] 2019 Dec; Vol. 39 (6), pp. 965-971. Date of Electronic Publication: 2019 Dec 16.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Injuries/*drug therapy
Brain Neoplasms/*radiotherapy
Brain Neoplasms/*secondary
Drugs, Chinese Herbal/*administration & dosage
Lung Neoplasms/*radiotherapy
Radiation Injuries/*prevention & control
Adult ; Aged ; Animals ; Brain Injuries/etiology ; Brain Injuries/metabolism ; Brain Neoplasms/metabolism ; Cognition/drug effects ; Cytokines/metabolism ; Down-Regulation ; Drugs, Chinese Herbal/pharmacology ; Female ; Humans ; Injections ; Lung Neoplasms/metabolism ; Male ; Middle Aged ; Radiation Injuries/metabolism ; Random Allocation ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The effect of ionizing radiation on the subcellular localization and kinase activity of protein kinase CK2 in human non-small cell lung cancer cells.
Autorzy :
Li Q; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li K; Pharmacy Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang S; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhou Y; Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hong J; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhou X; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li Z; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu B; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu G; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Meng R; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Pokaż więcej
Źródło :
International journal of radiation biology [Int J Radiat Biol] 2019 Nov; Vol. 95 (11), pp. 1462-1471. Date of Electronic Publication: 2019 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Radiation, Ionizing*
Carcinoma, Non-Small-Cell Lung/*enzymology
Gene Expression Regulation, Enzymologic/*radiation effects
Gene Expression Regulation, Neoplastic/*radiation effects
Lung Neoplasms/*enzymology
Casein Kinase II/metabolism ; Cell Cycle ; Cell Line, Tumor ; Cell Nucleus/metabolism ; Cell Survival ; Cytoplasm/metabolism ; Cytosol/metabolism ; Genotype ; Humans ; Naphthyridines/pharmacology ; Phosphorylation ; Signal Transduction
Czasopismo naukowe

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