- Tytuł:
- Acquisition of chromosome 1q duplication in parental and genome-edited human-induced pluripotent stem cell-derived neural stem cells results in their higher proliferation rate in vitro and in vivo.
- Autorzy:
- Źródło:
- Cell proliferation [Cell Prolif] 2020 Oct; Vol. 53 (10), pp. e12892. Date of Electronic Publication: 2020 Sep 12.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Chromosomes, Human, Pair 1/*genetics
Gene Editing/*methods
Induced Pluripotent Stem Cells/*metabolism
Neural Stem Cells/*metabolism
Brain/metabolism ; Brain/pathology ; Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Gene Duplication ; Genetic Vectors/genetics ; Genetic Vectors/metabolism ; Humans ; Induced Pluripotent Stem Cells/cytology ; Karyotype ; Neural Stem Cells/cytology ; Proto-Oncogene Proteins c-akt/metabolism ; Zinc Fingers/genetics
Czasopismo naukowe